ZMP

dbh

Ensembl ID:

ENSDARG00000069446

ZFIN ID:

ZDB-GENE-990621-3

Description:

dopamine beta-hydroxylase [Source:RefSeq peptide;Acc:NP_001103164]

Human Orthologue:

DBH

Human Description:

dopamine beta-hydroxylase (dopamine beta-monooxygenase) [Source:HGNC Symbol;Acc:2689]

Mouse Orthologue:

Dbh

Mouse Description:

dopamine beta hydroxylase Gene [Source:MGI Symbol;Acc:MGI:94864]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa21676	Essential Splice Site	Available for shipment	Available now
sa24865	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa21676

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000101089	Essential Splice Site	244	614	None	12
ENSDART00000123564	Essential Splice Site	None	192	None	11

The following transcripts of ENSDARG00000069446 do not overlap with this mutation:

ENSDART00000139403

Genomic Location (Zv9):

Chromosome 10 (position 10565416)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	10641282
GRCz11	10	10599520

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCATATCTATCAGCTCCCGCCAAATCTGCCCAAGAACCACATTGTCATGG[T/C]AACTTGAGAGCCACTCGCACATTACAAATAACCTTTCTATGTGAACTTTC

Long Flanking Sequence:

TGATTGGGCATTAAACATTGCTATTTCTAGGCTGATCAGTCAAGCTTTAAATGGGAAAAATATCTGATTATTTAAATTATTTGAGAAATGTTTGAGCAAGATGCTAATGGTCTAATCCTATTCAATGATTTATGCTAAGCTAAGTTAAAGGTGCTCTCACCAGACTTGCAGGTAGGTTGATTGGATTATACAATGGTAAAACTCAACTGTTTACCTAAAGATAATAATAAAATCTTTCCAGGAAGGCACTGTCCACATAATCTACACCATGCTGGAGCATCCCATCCTATCGTTGCATGAGCTCAATATATCCCGTCTCCAGCCTGGCGTCCAGCGAGTCCTGCTCCTGCGTCCAGACACCCCGTCCCCCCATCTCCCGAAAGATGTACGCACCCTGGAGGTCCTGGCCCCTGATGTCATCATCCCCACACAAGAGACTACTTACTGGTGCCATATCTATCAGCTCCCGCCAAATCTGCCCAAGAACCACATTGTCATGG[T/C]AACTTGAGAGCCACTCGCACATTACAAATAACCTTTCTATGTGAACTTTCAGAATGTTGTACCTATATAATTGAAGCATGTGAGGTACTTTGACCAATTATAATGCTCTTCAGTAAAACGCTAATGTAAGTGTGGGGTTATGGAAACTGAATCTGAATATAATTAGACTGAGTATGTGTGCGTTGGTGGTAAAGTGCTTGTGGAAGAGGCCTTCAGCCGCTTCTTTAGATGTGATGGTTTCAGGGTTTTACATGGAGGTTGGCAGCTCATTCCACCAGAGAAGAACAGAGAGGGTAAAGGTTTTCCTCACAATGAAGGAACAACAATGTTACAATGTAACAATGTTAACAATGTCAGTGACCTTAAATGCACAATGTAGAACTTATTGTTGTGTTTGAAGGCCATTTCACATTACACCAACACAAACCAACCTACCCTGCAGGCACAGGATGTCAACATGACGTCCTATTGACGTTGTACCCCAACGTATCCCAATGTCA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa24865

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000101089	Essential Splice Site	517	614	10	12
ENSDART00000123564	None	None	192	None	11

The following transcripts of ENSDARG00000069446 do not overlap with this mutation:

ENSDART00000139403

Genomic Location (Zv9):

Chromosome 10 (position 10539265)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	10615131
GRCz11	10	10573369

KASP Assay ID:

554-7864.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGCCACGTGGACACAGATTACCTGCAGAAATACTTCAGCCTCATCAACAG[G/A]TACAAAACACACACAACAACTACAGCAAACACAACCTTCCCCCGGTGAAG

Long Flanking Sequence:

CCTTTTATTTTATTATAACAATCATTAAATTTCAAAACTGCATAGAAAACATCAATAAAGGAACATTAAGGGGTACGTTCACCAAAAAAAAAAAAAAACAACAACAACAACAAAATAATCATTATCATTTACTCACCCACTTATATCATTCCAAACCTGTATGGCTAAATCAAAATGAGAAACAGCAAATCAAGTAAAGAGAAACTAAAGACTGACAGAAAAAGCATCATAACCTGTGCATTATGTTCTTATGAAGCCATTACTGTCAGTGTTGGAAAGAAATAATATATTACAATTTCTATCCAAACACTGATTACTGTATATATGAAAACACACTTCAAACCCATTGGCTACGCATTCTCTCATCCACAGGGTGGTTTTGGAATTATGGAGGAGATGTGCGTCAATTACGTCCATTATTACCCCCGAACGCAACTTGAGCTGTGCAAAAGCCACGTGGACACAGATTACCTGCAGAAATACTTCAGCCTCATCAACAG[G/A]TACAAAACACACACAACAACTACAGCAAACACAACCTTCCCCCGGTGAAGTCCAAAACACTTTCCAGACACTCTTTCATGAAAACCTTGAAAACATCAACAACAAACTGCAAACCTGAAACTAATGTCTGGCTTCAAGACTAACAGCCTGAGGACGAGAGGAGCACTTTCAATTCCTGCATCAAATCAGTCGGAAAAACAACCAAATATGTTTTCTTCTGCAATGCATAAACAAAAGAAAAGGCGATGGCATTTGTATTCATACATTTGGCGGCGACAAATTGCATTTTTCCAGCTTGTTTCTGTGACACTCCATATAGTGAAATCAGCCAATTCTGAAAGTCAAAAGACACTGCAGATGAATACCGTAGGTTTAAAAAAAATAATAATTTTATTATCATACTTCCCCAGTTGATTGTCAAGAATTTTTATGCAAATTAGTCATTGTTTTTAGCACAAAAATCTTACATTTAATGTTATTTTGACATATCAGAGTCAAAT

Associated Phenotype:

Not determined