Busch Lab

ZMP

brap

Ensembl ID:
ENSDARG00000008560
ZFIN ID:
ZDB-GENE-040718-168
Description:
BRCA1-associated protein [Source:RefSeq peptide;Acc:NP_001002466]
Human Orthologue:
BRAP
Human Description:
BRCA1 associated protein [Source:HGNC Symbol;Acc:1099]
Mouse Orthologue:
Brap
Mouse Description:
BRCA1 associated protein Gene [Source:MGI Symbol;Acc:MGI:1919649]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa21638 Nonsense Available for shipment Available now
sa6156 Nonsense Mutation detected in F1 DNA Not yet available
sa17070 Splice Site, Nonsense Available for shipment Available now
sa34813 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa21638
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109148 Nonsense 105 578 3 12

The following transcripts of ENSDARG00000008560 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 3350268)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3342462
GRCz11 10 3342766
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGACGTCAGCCAGACAGATGTGAACATGACACCCGACTCTCCCTCCAAA[C/T]AGCTGCCGGATCAGATCTCCTTTTTCAGTGGAAACCCATCGGTGGAGATC
Long Flanking Sequence:
CGCACAGATTTCGTGTGGGCCTACTGATTACCCTAACATGCCTAAGATATTTTTCAAGATACTAGTATTCAGCTTAAAGTGACATTTAAAGGCTTAACTAGGTTAATTAGGCAAGTTAGGGTAAATATGCAAAGCATTGTATAATGATGGTTTGCTCTTTAGACAATCAGAAACAAAAATGTTTCTTAAAGGGGCTAATAATATTGACCTTAAAATGGTTTTAAAAAAATAAAACAGCTTTTATTCTAGCCGAAATAACACAAATAAGACTTTCTCCAGAAGAAAAAACATTATAGGAAATACTGTTAAAAATTCCTGAATCGGTTAAATGTCATTTGGGAAATATTTGAGAAAAAAACTTTAAAAATTCTGACTTCAACTGTATTTCGACACCAGTTGGCCAGTAATGAGTGACTGTTATTAATTCAGGAGCTGAGGAAGGTAAAGAAGGTGACGTCAGCCAGACAGATGTGAACATGACACCCGACTCTCCCTCCAAA[C/T]AGCTGCCGGATCAGATCTCCTTTTTCAGTGGAAACCCATCGGTGGAGATCGTCCACGGCATCATGCACCTCTACAAAACTAAGTTAGTACTGTCTAGCTTTGCATCTATGCTAATACCCTCTCTTTTTTTTACTAGGTCTGGGTATCGATTCACATGTCCTGATTTGATTTGGTTTCACAAGCTCATGATATAATTAGATTTTTGATTCAATCCTCAAATCGATTCAGTGATTAAACATAAATGCTGTTGATATTTGGGAAAATAAGTAGTGAACACTTTATTACAGGTACTTAAAGGTCCTGTGAAGTGTTTTGTTTGTCATAATCTCTGAATATTAAACTGAAATATGAAATCACGTGTATTGCGTGATTTGTCGCTATTTTCAGACCAACTCAACTCTAATTTTTCCCATTTTGCGCCACATTCTTTAAATAGTAAATCCATTTGCGCCGCTCTGTGGACTCTTTGTGATACACAAATATCTTAACATATGAAAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6156
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109148 Nonsense 316 578 8 12

The following transcripts of ENSDARG00000008560 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 3361532)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3353726
GRCz11 10 3354030
KASP Assay ID:
554-5026.1 (used for ordering genotyping assays)
KASP Sequence:
ATYAATTATTAATATTTGTTCTYYTAGAATCTGTGGATCTGTCTCATCTG[C/A]GGTCACATCGGCTGCGGRCGTTACGTCAGTCGTCATGCTTACAAGCACTT
Long Flanking Sequence:
GTGCACTTCTTCTCCTGCAGGTGTCCTGTGTGCAGATACTGTCAAACTCCTGAACCCGTCGAGGAAAACAAGTGTTTCGAGTGTGGCGTTCAAGAGGTAACAGACCTGACTGATGTCTCATTCATGGCTATAATAGATGAATGATTATTGTAGATTAATAGTAATCAGCCAGTTACTTGCAGTTAAAGTCAAAACTATTCGCCCTGTGAATTTGTTTTCTGTCTTTGTTTGAAAGTATTTTCCAAATCATGTTTAACAGAGCAAGAACTTATTCACAGTGTTTCCCTTAATATTTTTTCAAAATCTGAATTTTTCCACCTTAGAAAAATTGTTAGGCTTCGTCCATTCTTAAACGTTGAGGCTTGATTACTGTAGTGCTCTTCCTCTTACAGCACATTCAGAATGTTCAGGGGCTGTAGTTTGGCATTCGCAAATGGATGTTTATGTGTTATTAATTATTAATATTTGTTCTCCTAGAATCTGTGGATCTGTCTCATCTG[C/A]GGTCACATCGGCTGCGGACGTTACGTCAGTCGTCATGCTTACAAGCACTTTGAGGAAACGCAGCACACTTACGCCATGCAGCTGACCAATCACAGGGTCTGGGACTATGCTGGAGGTGTGTGACATCTCAGTGCACTTGAGATGATGAAACGTGACCATAAATAATATTGCGTTCAATTTATTGCGTTAATGTCCATGCAGATATAATAATAGCTGTTATTTAAATTGTAAGTATCGTTTTCAGAGAAAAATAGTACATTGTAGAAAGAAGTTGCTAAGTTTTTAATATTTAAGATTTCGATATTTAAAATGATACTGTTTAATAGTAATACACTATTTAGAAATGATTAGATGTAGTTAATAATGTATTAAAATATTTTTATTTTGTTCGGACACTTAATTAGGTACACTTTACTAGTACTGGGTTGGCCCCCTTTTGCCCCCAAGAACTGCCTTAATCTTTCGTGGCATAGATTCATTAATGTACTGGAAATATTCCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17070
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109148 Splice Site, Nonsense 392 578 10 12

The following transcripts of ENSDARG00000008560 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 3363624)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3355818
GRCz11 10 3356122
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGTTAGATACTCTTCTCTCTCATATTTGAACRCTTTTCTGTYTCCAGTA[T/A]TCATATTTATTAACCAGTCAGCTGGAGTCTCAGCGCATWTACTGGGAGAA
Long Flanking Sequence:
TCAGATAACTACGTTCATCGGCTTGTTGCTAGTAAAACCGACGGGAAGATGGTGCAGTACGAGTGTGAGGGAGACACGTGTCAGGATGAGAAGATCGATGCGCTGCAGCTCGAGGTGTGTGTGTGTGTGTCTTTGTGCATTTGTGTTGTGTTCTTGTGTCTCTGTGTGCGTGTATGTATCTGTATGCGACTGCGTTCATGTGACTGTGTCTCTGTTCGTGTGTGTTTTTGTGTCTGTGAGTGCGTGCATGTACATTTGTATGTTTCTTTTGGGTGTGTGTATTTGTTCCTGTGTGTGTCAGGGCATATGCGTGAGTCTGTGCATGTGTGTATGTGTGTTTGTGTCTGTATAGGCATGTGTCAAAGGATGTATTTGAGTATGTGCGTGTGTGAATGTGTAAGTTTGTGTGCCTGCGTATCTGTGTGTGTGTGTGATATTGTAAGTTGTATTGTGTTAGATACTCTTCTCTCTCATATTTGAACGCTTTTCTGTCTCCAGTA[T/A]TCATATTTATTAACCAGTCAGCTGGAGTCTCAGCGCATATACTGGGAGAATAAAATCGTTCATCTGGAAAAAGACACAGCAGAAGAGGTGAGAACACATCCGTAATGCATTACCATGATCATAATAATCAGCCTGAAGTCAAATGAACAGCAGTGAAGCCGCTTCTCTTTGTGTTTTAGATCAACAACATGAAGGCCAAATTCAAGGAGACCATCGACAAGTGTGACAGTCTGGAGCGCAAACTCAACGAACTCGCCAAAGACAAACAGTCTATCGACAAGAAGTAACACACACTTTCAGCTTCATTCTGTTTACAACTGAAAAAGATTTAAATGTTTAAGAGTTCAGTTTTACATATAAAAACACATTTTTTTTTATTGTTATATATATATATATATATATTGTTAAAACCAGAAGTTCACATACACTGTATAAAAAGGCACATGACCATTTTAATAAAGTCAGATGTTAATGTGACTTAACTTCTTCACTTTTAGGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34813
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109148 Essential Splice Site 421 578 10 12

The following transcripts of ENSDARG00000008560 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 3363712)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3355906
GRCz11 10 3356210
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATACTGGGAGAATAAAATCGTTCATCTGGAAAAAGACACAGCAGAAGAG[G/A]TGAGAACACATCCGTAATGCATTACCATGATCATAATAATCAGCCTGAAG
Long Flanking Sequence:
AGAAGATCGATGCGCTGCAGCTCGAGGTGTGTGTGTGTGTGTCTTTGTGCATTTGTGTTGTGTTCTTGTGTCTCTGTGTGCGTGTATGTATCTGTATGCGACTGCGTTCATGTGACTGTGTCTCTGTTCGTGTGTGTTTTTGTGTCTGTGAGTGCGTGCATGTACATTTGTATGTTTCTTTTGGGTGTGTGTATTTGTTCCTGTGTGTGTCAGGGCATATGCGTGAGTCTGTGCATGTGTGTATGTGTGTTTGTGTCTGTATAGGCATGTGTCAAAGGATGTATTTGAGTATGTGCGTGTGTGAATGTGTAAGTTTGTGTGCCTGCGTATCTGTGTGTGTGTGTGATATTGTAAGTTGTATTGTGTTAGATACTCTTCTCTCTCATATTTGAACGCTTTTCTGTCTCCAGTATTCATATTTATTAACCAGTCAGCTGGAGTCTCAGCGCATATACTGGGAGAATAAAATCGTTCATCTGGAAAAAGACACAGCAGAAGAG[G/A]TGAGAACACATCCGTAATGCATTACCATGATCATAATAATCAGCCTGAAGTCAAATGAACAGCAGTGAAGCCGCTTCTCTTTGTGTTTTAGATCAACAACATGAAGGCCAAATTCAAGGAGACCATCGACAAGTGTGACAGTCTGGAGCGCAAACTCAACGAACTCGCCAAAGACAAACAGTCTATCGACAAGAAGTAACACACACTTTCAGCTTCATTCTGTTTACAACTGAAAAAGATTTAAATGTTTAAGAGTTCAGTTTTACATATAAAAACACATTTTTTTTTATTGTTATATATATATATATATATATTGTTAAAACCAGAAGTTCACATACACTGTATAAAAAGGCACATGACCATTTTAATAAAGTCAGATGTTAATGTGACTTAACTTCTTCACTTTTAGGTAAGTTGGGATTATTATATTGTTTCTGCTTAATAGCAGAATAATGAGAGATATTGTTTGAGAAATTGTTATAACTTTTCTTGAAAGTCAA
Associated Phenotype:
Not determined