Busch Lab

ZMP

ash2l

Ensembl ID:
ENSDARG00000060392
ZFIN ID:
ZDB-GENE-030131-494
Description:
ash2-like [Source:RefSeq peptide;Acc:NP_001103575]
Human Orthologue:
ASH2L
Human Description:
ash2 (absent, small, or homeotic)-like (Drosophila) [Source:HGNC Symbol;Acc:744]
Mouse Orthologue:
Ash2l
Mouse Description:
ash2 (absent, small, or homeotic)-like (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1344416]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa17333 Essential Splice Site Available for shipment Available now
sa17111 Essential Splice Site Available for shipment Available now
sa21633 Essential Splice Site Available for shipment Available now
sa21632 Nonsense Available for shipment Available now
sa31760 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa17333
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085031 Essential Splice Site 38 590 2 17
ENSDART00000124356 Essential Splice Site 38 463 2 12
ENSDART00000131749 Essential Splice Site 36 277 2 10

The following transcripts of ENSDARG00000060392 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 2813210)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 2758847
GRCz11 10 2786018
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
WCTGACCRCAAACATGGAGACCGAGTCGTCCAGTGGAAAGGAGACTATGG[T/C]ACTGWAGGATATTTGACACATGAGGAGTTGAACTTTCTAYAATTTCMACA
Long Flanking Sequence:
AAATTCAGATTTACTATTTTATGGAACGCAAAAGGCAGAATGTGCGAATTTAAAAATAACTTTACCTCAGTTTGGCAAAGCTGTAAAATTATTGATTAAAATTTTTGACAGCTCTGGTTTTCCAAAGACATGCGCTATACAGTAGGTAAATTAAATAAACTTGGTTATACATAGTGTATGAGTGTGTGTGTGTGTGAATGAAACATGCTGGAATAGTTGGCGGTTCATTTCACTGTTGTTGCGACCCCTGAACAGACTACGCTAGAGCAAAATGAATGAATTGATGATATATTTATAATTGACTTATTATTTATTTGGGCTGGGCTGTTTATATGTAAATGTGAGCGCATAATGAGCTGGTGTTTAAGAATGAATTACAGAGAATTTTCCGTCAGTTTCTGTGTCTCATTTTTGTGTGTGTGTGTATTGCAGAGATGCCTCTTTTGGAGATCTGACCACAAACATGGAGACCGAGTCGTCCAGTGGAAAGGAGACTATGG[T/C]ACTGTAGGATATTTGACACATGAGGAGTTGAACTTTCTACAATTTCCACAATGTTTTCAAAGTTTTTCAGTAGAGCTGTTAACCTACTCTAGTCTCACGGTTCGGTTACGATTATCATGCCATCGATTCGGTTCAATTCGATATCTCGGTGCATCACGGTGCATTGACGGTGCTTTCCATACACAGTTTTATATTTTCTTCACAGCAGCATTTCTTGTATTAAAATGTAAGAATATATTTACATTTATATACTATTTGTAATACAATTTTGTCATTTAATGCAAACAGTCAGATATATAAACTGTAACTTTAAACAAAACGAGCATTTAGCAAATAATATAAACAAATATAAATATCCAGCTCAATTTCTGATCCTTGTCTAGTTCTCTTACACCTCTTTGATTGGTCACACCCTCAACAAAAACGGTTGCGATTGGCTCTTGCGCGCTGCGCTCTTCACAGATGAGTGACACTGATAAGTCGCAGTGGCGATCTCCCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17111
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085031 Essential Splice Site 180 590 6 17
ENSDART00000124356 Essential Splice Site 180 463 6 12
ENSDART00000131749 Essential Splice Site 178 277 6 10

The following transcripts of ENSDARG00000060392 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 2805812)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 2751449
GRCz11 10 2778620
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCAGAGACCCGGCAAACTAACATGGCCAAATAACATCGTCAAAAYCATGG[T/G]GAGTTATTTGAATCTTTTATTATTTTATTRTCRGTCAATAATTTGGTTTA
Long Flanking Sequence:
TAAATGTCACTTTAAGCTGAACACTAGTATCCTGAAAAATATCTGGTAAAATATTATGTACTGTCATCTTAAAGAGAAAATAAATCAGTTGTTAGAAATGAGTTATTAAAAATCATGTTTAGAAATGTGCTGAAAAATCTTTCTGTTAAACAGAAATTGGCTAATAATTAGTCTAATATTAGGCTAATAGGCTAATAATTCTCACCTCAACTGTACAAACTCTACAAACTTTGTTGTCTGTTATGTCTATTGTTTGGGACATTGTGCATTTATAAAGGTGAATTTATAAAGTATCGATGTGAATTTGCAGGTTTATACATGCTGTGAGACGCAATGCAAATATTCAGAAAGAAATCCAGCAATAAAATATAACTGAAATAAATCATGTTCTTTGGTTGTAAAGGACATCATACCTTTCATTGACAAATATTGGGAGTGTATGACGACCCGCCAGAGACCCGGCAAACTAACATGGCCAAATAACATCGTCAAAACCATGG[T/G]GAGTTATTTGAATCTTTTATTATTTTATTGTCGGTCAATAATTTGGTTTAATAGTGTTTAATAAAAGCTGTGTTGTTTGACCTCAGAGCAAAGAGCGCGATGTTTTCCTCGTGAAAGAACATCCTGATCCTGGCAGCAAAGACCCTGAAGAGGACTATCCTAAATTTGGTTTGCTCGATCAGGTTTGACCTTTGACCCTATTCAACCGAATTTTGATGTTTCATGTACTTTGGAGACACAGATGTTTTTATTTAAAAGAGATACTTGAGGGATATTCTGGTCATACTGCGTTTTCTCATGATGGTGTTGATTTTAAAACTGTTGTAGTATTTTAATATCCATCATTGGCTGTCTTATACATTTTAAGAAGATCGAAATAATACTTTTATACTTATTGTTTTATATTTTGCCAAATTCTAAAAGATCTAAAAAGATCTAAAGTGTGTTTCCTGAAAAAAGACAAGGCTGGTTATGTTTCAAAGCTGTCTTTCTTTTTTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21633
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085031 Essential Splice Site 244 590 None 17
ENSDART00000124356 None None 463 None 12
ENSDART00000131749 Essential Splice Site 248 277 None 10

The following transcripts of ENSDARG00000060392 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 2802788)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 2748425
GRCz11 10 2775596
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTTCCTGTAAAGCTGTGCGTTGTATTCCAGGTGGATCAACCTTTTCAGG[T/G]GACTATGAGGTGTTTTACATGTGGCTTTTGAAACGGGAGGCTGGTGTTTG
Long Flanking Sequence:
CGCTCTTGGTTAGGGAAACGGGTTTGTTTTGGTCTAATGAAAAATCTATTATAGTTTCTCAAAATAGCAACGCGCCAGCGGTCCGCCTCAGAACGCCTTCCTTTTTAGACCAGAACGCCTATGGGCGCACATATGAGCGCTAATGCATTTGCTATTTAAACAGCGTAGCGCAACGCCTCAAAACCACTCTTGCGCCAAGCTGAAACTACCAAAAGACTACTGCACCATGCCTTGCGCCAACCTGCGCAGGGTGTATGATAGGGCCCCTTGTCTTTATTGTTAACAATGTTCTGTGTTTGGTTTTACCCAGGATCTGGGCAACATCGGACCGTCGTATGACAACCAGAAGCAGATGACCACAGTCACGGGTGCTGGAGGATTGAACGGTAAGACTGACGACCCCCTCATTGAAATGCTTCCAGTTGCATATTTGATTGTCATTGTAAAGGCAGTTCCTGTAAAGCTGTGCGTTGTATTCCAGGTGGATCAACCTTTTCAGG[T/G]GACTATGAGGTGTTTTACATGTGGCTTTTGAAACGGGAGGCTGGTGTTTGGTGCTCCTTTAACTTCCCCTCGCTTTGCATTGATCTTTGCGCTCTTGGTTGATTTGCTTGCTCCTCCTGGTCACTTTCCCCTCAATCTGCAGCCGGATGCTGGCACTAATGTTCGTTTCTGTGTGCTTGCACCCTGTCTTTTCCCTTTTAGACTCTATCTAACCATCATGGCTTTTGGCATTGAATGTACGGAGGTTTTTACGTGCTTAATTGTTGTCTGTCGAAAGCCATGGTCATTCGGTTGAACTCAGTCCCCGATCAACACTGTAATCTCTGCTAATGTTGAACTTTAAAGGTGCTGTATGTATGTTTTTGACTCTTCTAAAGCATAAAAATACCATGATGTGCTTGCAGATATTTTAGAAACATTGTAAGCATACTTGTTTATCTAAAAAACTATAATAATTATGATAAAGTCAGTTTTGTCCTTTGAAAATGTGCATTGTCCTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21632
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085031 Nonsense 495 590 14 17
ENSDART00000124356 None None 463 None 12
ENSDART00000131749 None None 277 None 10

The following transcripts of ENSDARG00000060392 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 2792240)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 2737877
GRCz11 10 2765048
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTACTTATACTTTGAAGAGAAAGATTATGTGGACAAGGCTGAGAAGAACT[T/A]GAAACCCACCAGTACCAGCAGAGTGAGTCATTCAAGACATTTTTTATATT
Long Flanking Sequence:
AATGACTACTTCAAAAACTGGATATAAAAAAGGAATATTACAGAAAACAATACAATATTTGTAAAACTACAATAGAGTTTTCAAATGTGGGAGAGAGAGCAGATAATCCAACAGCAAGTATTTTTTCTAAATCTGAGAAACTGTTAATAGTTGTTCTCATAGAGGTGATTAAAGTCATGCAAAATTATATTCAAGCTGAATAGATTTTAATGTTGTTTTATCCTAATATAGAAGCACTGGCCCGTTTTAACATTCAGTAGATGTCATGGAAATTAAGCTTTTAGTCAGTGAAAGTCGGGGAAGTTGATGTTTGGTAAACGTGGAAACCCTACTTTTTTTCACAACCATTTATGTCTTATTTTGTGCTTGTGTACTACAATTTTATTCTGTTATTTAGTTTATGTGGTATTGTTGTTTATTTTTCTCCAAGGCACTGATCAAATTCAAAAGCTACTTATACTTTGAAGAGAAAGATTATGTGGACAAGGCTGAGAAGAACT[T/A]GAAACCCACCAGTACCAGCAGAGTGAGTCATTCAAGACATTTTTTATATTTCTGTGTGTGTGTGTGCATGCGTGCGTGCGTGCGTATATAGAGGCGTTGGACTATAAAACTGAAACACTGACCAGTAGAGTGTTTGGGGTTTCATGGCTAAATTTGACCAGCCTGGTCTTCTGGTCTGATCTTCATTGATTGCACATTCCACCATTTTTATATATTTTTTACATTTATTTAATTATTTATTTGTGTGCATGTTTGTTTGTGTTCTATTTAAACATTATAATTAGGGGTGTAACGGTTCACGGTTGTTCTGTGATTCGTACTGATCTCAACCCACAGTTCTGAACACACGTGACCCGCAGATTAATACATTTTTTACATTTGTAGATTAATCCTAAATTTGTAAGAATCTCAGAGATTGCCTCTCACATCATTCAAATCCCATTTATAAGAGGGTATATATATGATGGGTTTCTTAGGTTATTAAAGGTGTTTTCTGTAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31760
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085031 Nonsense 584 590 17 17
ENSDART00000124356 None None 463 None 12
ENSDART00000131749 None None 277 None 10

The following transcripts of ENSDARG00000060392 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 10 (position 2786607)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 2732244
GRCz11 10 2759415
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACACACTGGCTGATATGCTGTACCACGTGGAGACTGAAGTGGACGGCCGA[C/T]GAAGCCCTCAATATGAAGGTTAATCACAAGCATCTGAAAACACTGACTGA
Long Flanking Sequence:
GGGAAACGAAGGACGCATTTTAAGACTGGGTTTGAAGGAGCCTTCGAATTTTTTTTAAAAATAAGACCACCTTCGTCACGCCGCGATGACCCAGCGCACTTCGAATGCATCCTTCGGAGGACACTGCTATTGATTCAATTTCAGGCGCATGTGCAACCAAAGTTGTCTCTATTTCAAGTGTGTGTGTGCGTTCGTTCGTTCGTTCTATTCGGACGTTCTATTCGGACCACTTGAATATATTTCAGCTTACTGAAGTGTGCTTGCCCAAAAGGCTGCCAGGGATTGTTGCGAGCTCCGAGTACACCAGGCCATTGATAATTAAATTTAAGAAAGCCGTCATGTTATTGCTCTATATTGAACATCATAATTGTAATGTTGGATCACCTGATTGGTATTTTGCATGTGTGTGTCTTCAGATGAGCGATATGGGTTGGGGTGCAGTCATCGAGCACACACTGGCTGATATGCTGTACCACGTGGAGACTGAAGTGGACGGCCGA[C/T]GAAGCCCTCAATATGAAGGTTAATCACAAGCATCTGAAAACACTGACTGACACACATCCACCAAATACAGACGCTTCCCTGCACCATTCTCAAACACACACACATAAAGCAGTTTGGCTATTATTTTGATTTGCAGTGCTCTTCTTTCCGTGTGCTGCTTTGTTTTCCGATTAAAAAAGTCAGCGGGTATTCGTCTCGTGTTTCACGTTTCTTTTAAGGAAACCTCAAACTGCACCCGACTGTGATGTTTGATCATTCAATCCAGTAAAACTAAATTAAATGACTCGAGCTGTAGAGTATTTGTATGTTTCCATTCGGTTAATAGTTTCCTCATACTGCAGATTTACCTTTGTATCCGTCATACTATTTTATTTCCTTCATACAATATCCTGACCGGCAGATTTCCTCTTAGCTGGTGTCAAGTGTGTGTGTGTGTGTGTCTCCGCCGTCTCGTTGTGCTTATCATCTGTTGTCTACTCCATCATGGGTTTGTAGTTATC
Associated Phenotype:
Not determined