ZMP

Ensembl ID:

ZFIN ID:

Description:

dual specificity tyrosine-phosphorylation-regulated kinase 1A [Source:RefSeq peptide;Acc:NP_0010741

Human Orthologue:

DYRK1A

Human Description:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A [Source:HGNC Symbol;Acc:3091]

Mouse Orthologue:

Dyrk1a

Mouse Description:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a Gene [Source:MGI Symbol;Acc:MGI:13

Allele Name:

sa27522

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100073	Essential Splice Site	75	734	None	11
ENSDART00000141723	Essential Splice Site	75	226	None	5
ENSDART00000144722	Essential Splice Site	71	222	None	7

The following transcripts of ENSDARG00000063570 do not overlap with this mutation:

• ENSDART00000131783
• ENSDART00000147674

Genomic Location (Zv9):

Chromosome 10 (position 210310)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	73478
GRCz11	10	73478

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

Flanking Sequence:

Long Flanking Sequence:

Associated Phenotype:

Allele Name:

sa15575

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
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Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100073	Nonsense	621	734	11	11
ENSDART00000141723	None	None	226	None	5
ENSDART00000144722	None	None	222	None	7

The following transcripts of ENSDARG00000063570 do not overlap with this mutation:

• ENSDART00000131783
• ENSDART00000147674

Genomic Location (Zv9):

Chromosome 10 (position 220539)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	63550
GRCz11	10	63550

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

Long Flanking Sequence:

Associated Phenotype:

Allele Name:

sa21625

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100073	Nonsense	623	734	11	11
ENSDART00000141723	None	None	226	None	5
ENSDART00000144722	None	None	222	None	7

The following transcripts of ENSDARG00000063570 do not overlap with this mutation:

• ENSDART00000131783
• ENSDART00000147674

Genomic Location (Zv9):

Chromosome 10 (position 220545)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	63544
GRCz11	10	63544

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

Flanking Sequence:

Long Flanking Sequence:

Associated Phenotype: