Busch Lab

ZMP

lrp2

Ensembl ID:
ENSDARG00000060649
ZFIN ID:
ZDB-GENE-050119-2
Description:
low-density lipoprotein receptor-related protein 2 [Source:RefSeq peptide;Acc:NP_001181916]
Human Orthologue:
LRP2
Human Description:
low density lipoprotein receptor-related protein 2 [Source:HGNC Symbol;Acc:6694]
Mouse Orthologue:
Lrp2
Mouse Description:
low density lipoprotein receptor-related protein 2 Gene [Source:MGI Symbol;Acc:MGI:95794]

Alleles

There are 17 alleles of this gene:

Allele Name Consequence Status Availability
sa17023 Essential Splice Site Available for shipment Available now
sa21599 Nonsense Available for shipment Available now
sa21600 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa17023
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085697 Essential Splice Site 3366 4632 50 77
ENSDART00000129237 Essential Splice Site 1826 3092 23 50
Genomic Location (Zv9):
Chromosome 9 (position 49660743)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 48915939
GRCz11 9 48613424
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACACCAACGACAAACTCTACTGGTCTGAYGCTCATCTCAACTACATTGAG[T/C]AAGACTCGCTCAGGYTTATATTCTGGGTGATTTAGTTAAATTCAATTYAT
Long Flanking Sequence:
GACTAAGCTGAAGGAAAATGAATGAATGAATGAATTGTTAAGTACAGTAAGGACTTTCATAACACTACGTACAGTATGCTGGGATATAAATTACAAATGTGCTTTATCTGAAATGAAAGGTGCTTTAAAAAGTGCTTGAGAGTCCTGTTCATGAAAGAGTGGGAGCCCTGCTTTTAGTAGCGATTGTTTAGTAAGTGATATGATCATTAATACTTGTTTTAATTTTTTTTAATACTGTTTTAGGTTATGGGCTTGCCAATGTAATTTCAGCTTATCTGTTTTCATGTCTAATGTAATGTACTGTACATCTTATGTCCTATTTGTGCAGGTATGTGTACTGGACTGACTGGGGAGAAAGAGCGTTCATTGGTCGTGTTGGAATGGATGGAAATAACAAGTCTGCCATCATCACTACCAAGATCGAGTGGCCAAATGGTCTGACCATCGACTACACCAACGACAAACTCTACTGGTCTGATGCTCATCTCAACTACATTGAG[T/C]AAGACTCGCTCAGGCTTATATTCTGGGTGATTTAGTTAAATTCAATTTATTTACATTGATTACATTGAATCTGACAATGACTTGGTTGTTGATTTGCATTTGTCTCTTCAAGTTGTTGTTTTGATCATTTTAAAACATGAAACATTATATAAACCTTAAAGTTTTGATTATGATTTTAATGTAAAATTTTGTATGAATTATAGAGAAAATTGATAAGAATGTAATACATTTCAGCGCCAATAGCCTAGTGGTTAAGTGTGTCGACATATAGAACCGTGGTGCTCAGTGACCCGATTCTCGGCTTGAGGTCCTTTGCTGACCCTTCCCCTCTCTCTGCTCCCAATACTTTCCTGTCTGTCACCTCCACTGTCCTATCCCAATTAATGGTGAAGAAATGTAATTTAATACATTTATATTTTGTATGATATTTATATTTAAAGATGTATGTTAAGTTTATATTTATTAATTGAGTTGCATGTTTTTAAAGTTTTTATTATCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21599
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085697 Nonsense 3825 4632 59 77
ENSDART00000129237 Nonsense 2285 3092 32 50
Genomic Location (Zv9):
Chromosome 9 (position 49688919)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 48944115
GRCz11 9 48641600
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCACACGCTACCCGAACAGCACCTACTGTCCACCCTTCCTGTTTGAGTG[T/A]AAGAACCATGTGTGTGTGCAGCAGCACTGGATATGTGATGGAGATAATGA
Long Flanking Sequence:
TATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTCATGTATCCGATTGGTATGTCATGTCATATACTGTATGTATGTAATTTTTTATTCATGTCTCCTCATAACTTTCAGTCAAAATACCTTCCCCTCCACCGTTTCAACATTATCTCTTTTCTGATAAACCTCATATCACTCATGTGAGATCCACTAATAGCGAACCACAATCATTTAATTAATTCGCCACAGAATTGCTTCATTTTTTATCTTTTTTGAGAAGCCATTCAGATATACAGCCCATTATCATAAACATCAGATTCTTGATTGCAGTGTTGGTCGCTTTTGTATGTTAAGTTTGATAAGCAAGTTTGTGCTGAGTTTGAGATGCTTGTGTTTATTTTTCAGCCACACGCTACCCGAACAGCACCTACTGTCCACCCTTCCTGTTTGAGTG[T/A]AAGAACCATGTGTGTGTGCAGCAGCACTGGATATGTGATGGAGATAATGACTGCGGGGACAATTCAGATGAGGAGCTGCATCTCTGCTGTGAGAAAAACACAGTCATCCGTCTATCCATCTATCCATTCAACTATTTATCCACCCATCTCTGATTACATTCACCTACCTGTACATTCATTCACCCATCCATTTATTTACCCACCCACCATCCATTCATCTGCTCATCCACCTTTTCACCAGCCACCATACATCCATCCATATTCACCACACATCCTTTCATTCATCTATTAATACATCCATCTCTCATTTACCCACTTATTCATAGATGATTCCATTCATCCATCCATCCACCTCTCCTTCCATCTTTACCTCATTCTATCCATCAATACATCCACGTATTCACCTGTCTGTCATTTCCATTCCCCAGTCCATGCATTCATCCACCCACCCACCGTCCATACATCCATTGAGCCTTCTCTCCATCCACCCATACATCCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21600
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085697 Nonsense 4536 4632 75 77
ENSDART00000129237 Nonsense 2996 3092 48 50
Genomic Location (Zv9):
Chromosome 9 (position 49712960)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 48968156
GRCz11 9 48665641
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGAACGTCAGTGCGGACCAGGTGGACAATAACTTCTCAAACCCCACATA[T/A]CAGCAGGCAGTGGAGGTGAAGAGCGAACAAGTAGAGGAGAAAAACACACA
Long Flanking Sequence:
TTATATTTATTAAAATATATACACTTATGCATATATATATTTATATATATATATATATATATATATATGTATGTTTATATATATGTTCATATAGAAATATATATGCAAATTAGCATGTTTAATTAAACATATGCTATCAACTAGACATGTTTATTTGCTGTTTAAAGTACCCAATTATTGACCGCTGCAATTCACTAATAAATATCATTCAATATTTACATTTTTTTATCTTGTTTCTCTGTTATTTATTATTAGGATGAGAATTTTGCAGACCCTGGACGACAGCCAATTACGTTTGAAAATCCTCTGTACTCGACTGCAGCCGCTCCGTCCAGTGATCCTGCAGTAATACACGCTACACAGGTATTGTTACCGCTACAGAACTCTCTAGAAATGGCTAACAGGTGCGGGTCTTTAGTTTTGTGTTTCTGTGCTTCACTAAAGGTCACTGTGAACGTCAGTGCGGACCAGGTGGACAATAACTTCTCAAACCCCACATA[T/A]CAGCAGGCAGTGGAGGTGAAGAGCGAACAAGTAGAGGAGAAAAACACACAGGTAAATAAAGTGACCACATTCATCATTTTAGCCATTATGTTAACACACTATTTTGTTTTGTTTTATTATGTTTTTAAAGATTTATTCATTATTTTATATTCATAATATATTTTCTTTTTAATTTTAATCTAAATTTGATTTCATTTATTTAATATTATTATTTGTTGTTTTATTTTGTTTTTATTTATTTTAGTATATTTTATAATTAATATTTTAATTTATATTATTTATTTTACATTTATACTTATTTATTGTTTATTTTTATTGTAATATTAGTTACAATTTGTACTTTATTTTATTATTTAGACTATCTAATTTTATAATTTGTTGTTTTATTATTTTTATAAAATATTTTATTTTATTTTATTTATTTTACATTTGATTTTAATTTTATTTAAAAATATATTTTATTTTATTATATAGATTATGTTTTAATTTATTTTTATGTT
Associated Phenotype:
Not determined