ZMP

arhgef11

Ensembl ID:

ENSDARG00000052482

ZFIN ID:

ZDB-GENE-070604-1

Description:

rho guanine nucleotide exchange factor 11 [Source:RefSeq peptide;Acc:NP_001027010]

Human Orthologue:

ARHGEF11

Human Description:

Rho guanine nucleotide exchange factor (GEF) 11 [Source:HGNC Symbol;Acc:14580]

Mouse Orthologue:

Arhgef11

Mouse Description:

Rho guanine nucleotide exchange factor (GEF) 11 Gene [Source:MGI Symbol;Acc:MGI:2441869]

Alleles

There are 6 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa20855	Nonsense	Available for shipment	Available now
sa15205	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa20855

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000017140	Nonsense	35	1406	2	40
ENSDART00000136594	Nonsense	46	524	3	19

Genomic Location (Zv9):

Chromosome 7 (position 6311663)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	5346001
GRCz11	7	5467648

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TCTACTCATCTTTATATTTTCTGTTCCTCCTGATTTGACAGGAACGGGTT[T/A]GGTCCAAAGATGCGTGGTCGTGCAGAGGGACAATCTGGGGTTTGGCTTCA

Long Flanking Sequence:

TAGGACTCACACAGACCACAGGTTGAGCGCCCCCTGCTGGCCTCACTAACACCACTTCCAACAGCAACCTATTGTTCCCTAGTGGTCTCCCATCCAGGTACTGACCAGGCTCAGCCCTGCTTAGCTTCAGTGAGTAACCGGTCTTGGGCTGTAGGGTGATATGTCTGTGATTGAAAAAAAGTGTATGGATACAGCTAGAGCTTGCTTGTTTTTACACAAATATCTAAAACATAATTTTTTTTATTATTTATTTATTGCTGTGTTATTAAATGTATTTAAATTATAATCATTTTTTGATAGGGCAAATAAAAATCTTTTTACATTTGTGCCATTCTTTAGCATTTAGCCCTTCATGAGTCTAAAATTTCATTCGTAATTGTCTTAAAATGTCATTTAAAAGTCTTAAATTTAACTCAGTGAAACCCTGTTATATTTATCTGTTTATATTCATCTACTCATCTTTATATTTTCTGTTCCTCCTGATTTGACAGGAACGGGTT[T/A]GGTCCAAAGATGCGTGGTCGTGCAGAGGGACAATCTGGGGTTTGGCTTCACGGTGTGCGGAGAGAGAATCAAACTGGTGCAGAACGTCCGGCCGGGTAACAAACACTCTTTGTTTTGGGTCAATAAGATTTTATTTGAAGTTACATTAACACTTTAATTTAATGTGAGTTTGTTAAATTGATCAAAAGTTATAGAGTGCAGATTTTTAAGATTTCAGATAAATGCTGATTTTCATCCAGAAATCTTGAAATACATATATCACAGTTACCACAAAGGTTTACTAATAATTGTTTTGTACATTGATATTAATGAGACATGTGCAGCCAGTCATTATATTAGAAAGATTTCTGAAGAACAGTGTGATATTACAACATGATCTCACGGCAATTCGTAATTTTTTATGGAGACAGATAAGACTCATAAGTAATTCACGCAAAAGACACGATATACACATGCGTAGCCAAATTCACGTGCGTAAAATATTTATTTATATTCACAAA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa15205

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000017140	Essential Splice Site	801	1406	26	40
ENSDART00000136594	None	None	524	None	19

Genomic Location (Zv9):

Chromosome 7 (position 6256699)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	7	5291127
GRCz11	7	5412843

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

CAGAGAATCAGTGATMGTTCAGGGCATTGGAGACATCATGCTGGCCAGAG[T/C]GAGTCTCATTTCTCTGTCTTCATCTCWGGATTTCKGTCTGTGTTGGTGAA

Long Flanking Sequence:

CTTGATAATTTTATTCATGTCTATATTCTAAAGGTTTTTACTGAAGGGTTTGTTCATATATAATTTGAGTCATTTTAGGGAACATTTTATACATCATAACCTGATCAAAATGTGTTTAATTCTGGCTTTAATATTTTATTTTTCTAAAACTTTCAACACTATTTAAAATTCATTCTATTAAAACCTTTATTGCTAATATATCAACAAAATTACTTACTACAATGACTTAATTCATTGTTATGCATTATTTTGTGTACATTTTCTCAAAATATTCTGATTTAACTTTACAGCATATGTAATCATGCAAAAAATGCCATCATCAATGTAATAAATCAGTTAAATTAACCATATTCTTGTCTGAAGTCCTGCGCCAATACTAATGTTGATTTTGGTATTTAAATCTTAATTTTTTTGTCTTTCAGCAAGTTTATGTGAGTCCATGAAGAAGTGCAGAGAATCAGTGATAGTTCAGGGCATTGGAGACATCATGCTGGCCAGAG[T/C]GAGTCTCATTTCTCTGTCTTCATCTCTGGATTTCTGTCTGTGTTGGTGAAGTGTGTGTTTTTACCAGTGTTTGTGTGTGTTAGTTTGAGGGAGAGGCTGGAGATCAGTTTGAGGAGCAGGTTTCGCATCTGTGCAGTCAACAGAGTCCAGCGCTGGAGCTCATCAAGAACAAACAGCGAAAAGACCCTCGATTCGCCCACCTCATACAGGTAATTCAACGGCACAGTTTATTTGCACTGATTATCTGAAGTAATTTAATCTGATGGCAGATCTGTTTACATGGACTCTAAACATTGTAATCTCATTCAAGCATCCATCTATGATATATATTCTGATTAAAACTTTAGCATTTAATAATGTTTAAGTTCAACGCAGGGGTAAGCAGAATGATCTTGTTTTGCTTTGACATAGCATTTGGTCACACTTTATTCTGATGGCCTGTTTGTTGAATTTATTTTTCTGTGTTTCTGTGGTGTTTTTCAGGAGTGTGAGGCCAGTCC

Associated Phenotype:

Not determined