Busch Lab

ZMP

tie1

Ensembl ID:
ENSDARG00000004105
ZFIN ID:
ZDB-GENE-990415-55
Description:
Tyrosine-protein kinase receptor Tie-1 [Source:UniProtKB/Swiss-Prot;Acc:O73792]
Human Orthologue:
TIE1
Human Description:
tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [Source:HGNC Symbol;Acc:11809]
Mouse Orthologue:
Tie1
Mouse Description:
tyrosine kinase with immunoglobulin-like and EGF-like domains 1 Gene [Source:MGI Symbol;Acc:MGI:9990

Alleles

There are 9 alleles of this gene:

Allele Name Consequence Status Availability
sa9781 Nonsense Available for shipment Available now
sa14772 Essential Splice Site Available for shipment Available now
sa20737 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa9781
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003701 Nonsense 371 1122 8 23
Genomic Location (Zv9):
Chromosome 6 (position 33696580)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34014245
GRCz11 6 33998935
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAGCCACAAGATCACATGTTCTGCARCAGGCCATCCACTGCCTAGCCATT[T/A]GAGYATCGAGCTACGCAAGCTGGAAAGCACCGTTCTGAAGGTGAAAGACT
Long Flanking Sequence:
TAGATTAGACTAGAACAAGTAAACTTATGCAACAAGATAGTATGTAAAATGATGTTATAAAGTATTTCATATTTAATCGATAGAGTAAACAAGCCAAGTATACTTAAAATAAGTATATATACAAAAGATAACTACAAAGGATGTATAATTAATTATTATCATTATTATTTCGATAGCCTGTCTTGAAGGAATGTACGGTGCTGACTGTCTCCTAAGTTGCAACTGCAAGAACAAAGGCAAATGCAATCGATTTAGTGGCTGCCAATGTTCTACAGGCTGGAGAGGGCAATACTGTGAGAAATCAGGTCAGTCTTCAAGACTACTTTTCCATCTGCTTTAAAATCTGCATCGTTTGTTCCTCTTGGCGCCGCTGTCTAACCTTATCCCTCTTTCAGATCGCGCACCAGAGATTTTAGACATAGCCAGTAACCTGGAGGGAAACTTGAACTCAAGCCACAAGATCACATGTTCTGCAACAGGCCATCCACTGCCTAGCCATT[T/A]GAGCATCGAGCTACGCAAGCTGGAAAGCACCGTTCTGAAGGTGAAAGACTAATAGGTTTAAGAAGCTGCATATAAGGTGAAAGAGGGAATGTTTTAAAAAAAGTGTAAATATTGTTGTGTCTACAGATCTAATGTGGTGGCAGTCTTTTGATTCTCTACTGTTGATTACTTAGGCATTCCACACTATTTTGGACTCCAAAAAAAGCACAGCTCACTTTGAGATCCCACGTCTGTCTCCAGAGCACAATGGTTTGTGGGAATGTCGAGTCTCGACCAATGGTGGGCAGGATTCTTTGAAGTTTACCTTAACTGTGAAAGGTGAGATTACATTTTAATATTGTTTTGTTGAAACCCACATGAGCTTCATATTAGCTTCAGATGTGCAATCACATGTTCAAATCACATTCAAATGTGAAATATACGGAACAAGTTAAACGTGGCTTTCATGTGAAACTCATGTGAGCACCTGTGAACAAATGTTAAAAGTGTGGAAGTATGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14772
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003701 Essential Splice Site 723 1122 13 23
Genomic Location (Zv9):
Chromosome 6 (position 33692323)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34009988
GRCz11 6 33994678
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGKACCTGGAGAGTGGAGCAGCTTCGTACAAGCTCAGACACCTGGAGAAG[G/A]TAGGAGACTAGGAGAAAATACTGAAATAACAACATAAATTTGTTTTCTTA
Long Flanking Sequence:
CTAGTAAACTGTGGCAGCCATGGGCCCCCTTCAAGACCCCATCATATTCACATCTATAAGCAGGGTAACATAAATCTTCCATGTCCCCAAGTAGGCAAAAGAAGGATAGAACAGGAGATTAATGCTAGACAGGATGTAATGAAGCAAATATGCATACTATACTGTTCAATTAAACTGGAATAGTAAAATTGTGTATGATTCCTCTCCAGGCCCTTCTTCTCCACGAAACGTCCAGGCCGACGCCCTGTCCATTAGTGCAGTCAGGCTTCGCTGGCAGCCACCTGAAGATCCCAATGGAGGCATTGTAAAATACAGCATTGAATACCAGCCAGTGGGCCAGAGCAGCTTGCATCCTTGGGTAGACACAGACAATGGCAACAAAACCACAAAAGATGTAACATCCCTCAATGGGAGCACATTGTACCAATTCAGAGTGAGAGCTTTCTCTAAGGTACCTGGAGAGTGGAGCAGCTTCGTACAAGCTCAGACACCTGGAGAAG[G/A]TAGGAGACTAGGAGAAAATACTGAAATAACAACATAAATTTGTTTTCTTATTGTCCTTCTTATTGTCCTTCCTTAATTTCCCATGTATCAGGATTATCCAGCTTTATTCCCACCACTCAGCAAGTGGGACGGCCGTTGGCTGAGGATCATCAACTTCTTTTTGCTGTGGTTGGGTCAGTGGCTGTGACTTGTGTGACCATTCTACTGGCTCTTCTGGCCCTCTTTTACATTCGTAAATCTGTCCTTAAAAGAAGACGGACATTCACCTATCAGTCTGGATCTGTAAGTAGACATGTCATTACTTTAGACTCTACAAAATGCTGGGTCACTTTAAATTTGGATTGCATATGGACAAACTCAACTGCTAGGTTAAACTATATTTTTAACTCAACAGCTGGGTTCATCCACATTTGACCCTAATTTGAGGTGAAACAACCCAGCATTTTTTAGTGTAGTTTGATCATTTTTCAGTGTTTAAAGATCACCTATGATGAAAATCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20737
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003701 Essential Splice Site 1066 1122 21 23
Genomic Location (Zv9):
Chromosome 6 (position 33685173)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 34002838
GRCz11 6 33987528
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCCCAGGGATACAGAATGGAGCAGCCCAGAAACTGTGATGATGAAGTG[T/A]AAGCAGAAGATTGATCAACTGAAGCTGTAGTAATATTGCATTTATTATCA
Long Flanking Sequence:
AACATTTCTAAAAATTCTTGTTTATTTTGAAGTAATCTGCTTTACATTTAATTATTTCTCTGAAATGGGGCGAATTTGAACAAGGTGACTTTGTCAAAGGACAGAACAGATGTCAAATCCTATTATAGTCATTAATTAAATTTCAAACAAATATAGTATTTACTATGCAGTATGCATTTTGGATGTACTTTATATACATTACAGCTTCATCACAATTATGCTGATTATTCTTTAATTGAAATGTCTGCCTTTGGGCTTTCAGATGGTCTTTTGGAGTTCTTCTATGGGAAATAGTGAGTTTAGGTAAGTGTGTTACTAGTTTCAATGAATTGCTCTCCACTTCCTCTTTGCATATTAAGCATGTTCCAGCCAGGTGAATTAGATGAGTTTGTTCTCCTCTAGGTGGGACGCCATACTGTGGGATGACCTGTGCTGAGCTCTATGAGAAGCTTCCCCAGGGATACAGAATGGAGCAGCCCAGAAACTGTGATGATGAAGTG[T/A]AAGCAGAAGATTGATCAACTGAAGCTGTAGTAATATTGCATTTATTATCACTGATATATTTACAATTATCCATGCAGGTATGAACTTATGAGGCAGTGCTGGCGAGATAGACCTTATGAGCGACCGCCATTTTCACAAATATCTGTCCAGCTTAATAGGATGCAAGAGGCACGGAAGGTAAGCGAAAAACAGACAGATGTTTCACAAACTGTACTTAAAACATTTTTGGGGGGGAGTGGTTGCTGTATAGATATAGTAAGGTGAGCAGATTTCTGAAAAAGAAACCAGGGACATAATTCTATACAGTGGTCAAAATTTCACTCAAATCTGTTGTTCATTCATTCATTCATTTTCTTTTCAGCTTATAAGGTCTGATTTCTTTAAAAGTCAGTGAACTGTAGGTAACAAACAAGTCTCAATGAATCAAGTACTCTGATTAGGTGTTTAATGACGGTTGGAACTAAACTATGCAGAGCTGTGGCCCTTCAGAAACTGAGTTT
Associated Phenotype:
Not determined