Busch Lab

ZMP

MYLK (1 of 2)

Ensembl ID:
ENSDARG00000004753
Description:
myosin light chain kinase [Source:HGNC Symbol;Acc:7590]
Human Orthologue:
MYLK
Human Description:
myosin light chain kinase [Source:HGNC Symbol;Acc:7590]
Mouse Orthologue:
Mylk
Mouse Description:
myosin, light polypeptide kinase Gene [Source:MGI Symbol;Acc:MGI:894806]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa20669 Nonsense Available for shipment Available now
sa20668 Essential Splice Site Available for shipment Available now
sa1486 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa20669
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027684 Nonsense 425 966 7 17
Genomic Location (Zv9):
Chromosome 6 (position 13388060)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 13245339
GRCz11 6 13478874
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTCTTGGTATGGGCCCACTTATGATGGTGGCAGCATCGTCCAGTCGTA[C/A]AACCTGGAGATCTGGAACTCGGTGGACAACACATGGAATGACCTCACATC
Long Flanking Sequence:
CTCATTTGAGTACCTGACTTTAGTAGTATTAAAAAACACTATAGTACCATGATATGTTGGGCCACACTTTATTATAATGTATTCACACTATTTACCAAACCATTAACTAATACTTTTAGTTAAATAAACTAATTGTTAGTAAGGTAGTAGTTAGGTTTAAGTATTGGGTAACTTTAGAGATATAAAATAAGATCATACATTCTGGGGAAAAAACCCAGTTAAAGTCTTAATAACAAGCACCTAATAAGACAGTATAAATGATCTGAATTGTTACTTAAACTAGAGTGTTAACAACTTTATTATTAAATTAGATTATTCTATTTAATTTTGGGTTTGATCCCTTATTTCTTTCTATACCATTTATTTATTTTTATTTATTTTTTGTCAGATAAGCCGGACCCTCCAGCTGGTATCCCCGCTGCCTCTGATATCCGCCGGTCCTCGCTTACTCTTTCTTGGTATGGGCCCACTTATGATGGTGGCAGCATCGTCCAGTCGTA[C/A]AACCTGGAGATCTGGAACTCGGTGGACAACACATGGAATGACCTCACATCCTGTAACAGCACATCTTTCCATGTCCAGAACCTCCTCAGTGACCGTCAGTACAAATTCCGGGTTCGAGCTGTGAATGTGTATGGGGTTGGAGAGCCCAGTGCAGAATCTGGACCCATTGAAGTGGGAGCGGAGGAGGTTACAGGTGAGAACGAACATCTGCTTATGAATACTTTTTGTCATTATTGATCGAGAAAGAATCAGTCTGGTCAAAATGTCATGGAAACACCTTCAAGGAAAATTAAAATTGTAGGCAAAATTATTGTCTCAGCAGAATCGTTCATTACTTTTCATGCTTTTCCCATTTAACAGAAAAGGGACTTGTTTTCTGTAGCTTTTCCACAATTCGCGAACTCAATGCTCAGCCTTTGATAATCTGCCTCCAAATTCTTTCATTCATTCATTCATTCATTCATTCATTTTCTTGTCGGCTTAGTCCCTTTATTAATCCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20668
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027684 Essential Splice Site 603 966 10 17
Genomic Location (Zv9):
Chromosome 6 (position 13384541)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 13241820
GRCz11 6 13475355
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATGGACGCCTTCGAGGGAAAATCGGACATGGTCATGGTCATGGAGATG[T/C]GAGTCTCTAACCTAATCAAAAATCCGAAAGGCTAATGTGAAGCAGATTGA
Long Flanking Sequence:
GCTGTGTCTGATGATGGTACGAAGTTCAAAGCATTTAGCCCGCTGATCCATTCCTCACAAATCCAGAGTTTACTAACACGACTCCCACATGCTCTGTCTGATACATATCCTGTTAACTTCACAGATGAAGAGAAAGAGCCAGAATATAGAGATGTGGTCATTAAGAAAGACTGCAGCGTCAAGGACTTCTATGATATAGAGGACCGCTTAGGAACGTAAGAGTCTGCTATTTCCATCAATAGTCTGGCTGAATGGTATAAAATAGTACTCTTATAACCAATTTCTCTCTCTTTAGGGGTAAATTTGGTCAAGTCTTCAAACTAGTGGAGAAGTCCAGTAAAAAGGTATGGGCAGGGAAGTTCATCAAGGCATTCTCACAAAAGGAAAAGGAGAACGTGAGGCAGGAGATCGGCATCATGAACAGCCTCCACCACCCCAAACTGGTGCAGTGTATGGACGCCTTCGAGGGAAAATCGGACATGGTCATGGTCATGGAGATG[T/C]GAGTCTCTAACCTAATCAAAAATCCGAAAGGCTAATGTGAAGCAGATTGAAGGAATTCAGTTCAGCTCAGTTTATTAGCATAGAACTTTTCACAATACACTTTGTTTCCGCAAGAGATTCGTAATACTGACAAAAATATATTGTTTGAACCAACTTTTTGCCACTAGGGTGGTACCTTTTCAGTACAATTTTATATCCAAAGACTTCACAGTGGGAACTTAAAGGTACACATTAGTAACAGAATATTCAAAAGTTATGTTATTGCACTGTTTAGGTACCAGTGTCAGGGGCGGACTGGCCATCTGGTAATTCTGGCAAATGCTAGAAGGGCTGGACCATTTTTTAATGTGGGCCGATTAGTTTTTTATTTTAGTTTATTTTTTTAAATATGTATTGTTTTTACATGCAGTGAGCTTTTATCTCTTGCTAGATGTGATATTATGATGATGATGATTATAGAAATAACAATAATAACAATAATAATAAATGTTAAGCATTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1486
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027684 Nonsense 623 966 11 17
Genomic Location (Zv9):
Chromosome 6 (position 13379255)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 13236534
GRCz11 6 13470069
KASP Assay ID:
554-1411.1 (used for ordering genotyping assays)
KASP Sequence:
GCGGMGAGCTGTTTGAGCGAATCGTGGATGAAGATTTYGAGCTGACCGAG[C/T]GAGAGGTGATTAAGTACATGCTGCAGATCATAGATGGAGTCCAGTTCATC
Long Flanking Sequence:
CATCAGGTCAATTTGATGAACCTACTCTGCAATTCTTGTAGTTTTTGAACAGGTCGTGATGTTTGTTAGTTGTCTTCCAACACCTTTAAATCATTCCACCAGTTTAGCTATTTATGGTGTGGGTGGAATGCGAAATCCAAGAGTGTGTGATTGGAGATGCGCGTGTCACAAGCCCTTATATAGCTAGATGGAGAAACAAAGAGGTGGGGAGGGAAAAGTATGAATGCTCTCTTTCTCTGTTTGGCAGCCATGACGGAAAATAGCCCAGATTTAAATCTCCCTGACTGTAAGAGAATTGTTTAGCGCTCCAGGCAGAGACACTGTTCGTATGCTTGTTAAATGGAATGTGCATAAACAAGTTTAAAACGTTTCAATTGCAGTCTGACAGTGATTGGTTAGCATCACCAAATGATGATGTCACTGTGATCCCTATTGGCTGCAGGATTTCTGGCGGCGAGCTGTTTGAGCGAATCGTGGATGAAGATTTCGAGCTGACCGAG[C/T]GAGAGGTGATTAAGTACATGCTGCAGATCATAGATGGAGTCCAGTTCATCCACAAGCAAGGCATCGTCCACTTAGATCTTAAACCAGAGAACATCATGTGCATAAACAAGACCGGAAGCAAGATCAAGCTCATTGACTTTGGGCTTGCTCGAAGACTAGGTAAAGAAACACGAAAACAAACATGGTGTCTGGTTTTCTGGCACAGATTTATATGTTTTTATTTTCTGCTTACAGAGGATTCTGGCTCTCTGAAGGTTTTGTTTGGGACTCCTGAGTTTGTTGCTCCTGAGGTGATCAATTATGAGGCTATCAGCTACCCAACAGACATGTGGAGCATTGGCGTCATCTGTTACATTCTGTAAGTGACAAATCGGTACAACTCCTCCAACAGACCCTTAAGATCCGCGGCACGTAAAGACAAAGTAATCAATGCTGCAAACTGCAAACATTTCCTTTTATGGACTTCATAGAGTTTTTAGACAGCTTGCTTTTTCATTTTA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461