ZMP

si:ch211-142p3.1

Ensembl ID:

ENSDARG00000067634

ZFIN ID:

ZDB-GENE-070705-36

Description:

Novel protein similar to vertebrate Rho guanine nucleotide exchange factor (GEF) 12 (ARHGEF12) [Sour

Human Orthologue:

ARHGEF12

Human Description:

Rho guanine nucleotide exchange factor (GEF) 12 [Source:HGNC Symbol;Acc:14193]

Mouse Orthologue:

Arhgef12

Mouse Description:

Rho guanine nucleotide exchange factor (GEF) 12 Gene [Source:MGI Symbol;Acc:MGI:1916882]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa17710	Nonsense	Available for shipment	Available now
sa20550	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa17710

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > G

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000087610	Nonsense	947	1336	27	35
ENSDART00000144670	None	None	248	None	8

Genomic Location (Zv9):

Chromosome 5 (position 60181911)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	5	58043529
GRCz11	5	58713238

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GCTGGAGGATATATTGGTGCTACTTCAAAGGCAGGATGAGAAGCTGATCT[T/G]AAAATGCCACAGTAAGAATCTGGCRGGCACCGCTGAGACCAAACACAWCT

Long Flanking Sequence:

TATGTAAAAACTAACTAACAATAGTTATTATACCCTTTTATGTGTTGCAGGCATATTTAAATGTTAAGACATCTGCTAATTTAACAAATATCATTTACCATTTTATATCTATTTCATGATTTTTTTTTCTCTCCATGTCCAGAGCTTGGACTTGACCAAGAGGAAGATGGTGCACGAGGGGCCGCTGTCCTGGAAGGTCAACAAAGACAAAACCATTGGTGGGTGTGGCTTTTTTACAGAATTAATATATATAGACCAAACTCACAGTAGGTCAATATCCTAAAGATCTCTTACAGGTGCAGTAATTCTGAAGAAGAAAATCACTTTTGACTGTGTTTTCCACAAAGCGACATCAAGGCAAAACCGAATGCTGTGAACGAGTGATGTCTTGTAATGTCATTGTGAAATGATTTCATGTGCGTGTGTGTTTTCAGAGCTGTACACGTTGCTGCTGGAGGATATATTGGTGCTACTTCAAAGGCAGGATGAGAAGCTGATCT[T/G]AAAATGCCACAGTAAGAATCTGGCGGGCACCGCTGAGACCAAACACATCTTCAGCCCCATCATCAAGCTCAGCACTGTGATGGTGCGCTCCGTTGCCACCGGTACGATAACAGAGATGTTAAAATCTGACAATGTGAATGCTTAAAGCTGTAGTTCACGGAACAATTTTTCAAATGATCTTATAATTATCAAAAAACAGAGAAATATTCTGTAGCATTTTCTTTAAAGGTGCAGTAGGTGATCTGCCAGAATGCTAGCGTTAGCATAATAGCTTACGTCCCTTCACTGCCATCAAATACCATGGAACCCGCACCGAATAGATGATGAACTGATGATGATAGACAACCTTATATAGCTCTAGACCATGTCATTCACCAGTTAGAAAAATCTTTGAAGACACACACTTTGTCCAGCATAGTTGTTGACAGCCCGGGGGGTGCAGGAAATGTATTTCCCCAAAACTGGCATTGGGGTAAAGTTGGTTTTATATTGGCACAATT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa20550

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000087610	Essential Splice Site	981	1336	27	35
ENSDART00000144670	None	None	248	None	8

Genomic Location (Zv9):

Chromosome 5 (position 60181808)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	5	58043426
GRCz11	5	58713135

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGCCCCATCATCAAGCTCAGCACTGTGATGGTGCGCTCCGTTGCCACCGG[T/C]ACGATAACAGAGATGTTAAAATCTGACAATGTGAATGCTTAAAGCTGTAG

Long Flanking Sequence:

TATATCTATTTCATGATTTTTTTTTCTCTCCATGTCCAGAGCTTGGACTTGACCAAGAGGAAGATGGTGCACGAGGGGCCGCTGTCCTGGAAGGTCAACAAAGACAAAACCATTGGTGGGTGTGGCTTTTTTACAGAATTAATATATATAGACCAAACTCACAGTAGGTCAATATCCTAAAGATCTCTTACAGGTGCAGTAATTCTGAAGAAGAAAATCACTTTTGACTGTGTTTTCCACAAAGCGACATCAAGGCAAAACCGAATGCTGTGAACGAGTGATGTCTTGTAATGTCATTGTGAAATGATTTCATGTGCGTGTGTGTTTTCAGAGCTGTACACGTTGCTGCTGGAGGATATATTGGTGCTACTTCAAAGGCAGGATGAGAAGCTGATCTTAAAATGCCACAGTAAGAATCTGGCGGGCACCGCTGAGACCAAACACATCTTCAGCCCCATCATCAAGCTCAGCACTGTGATGGTGCGCTCCGTTGCCACCGG[T/C]ACGATAACAGAGATGTTAAAATCTGACAATGTGAATGCTTAAAGCTGTAGTTCACGGAACAATTTTTCAAATGATCTTATAATTATCAAAAAACAGAGAAATATTCTGTAGCATTTTCTTTAAAGGTGCAGTAGGTGATCTGCCAGAATGCTAGCGTTAGCATAATAGCTTACGTCCCTTCACTGCCATCAAATACCATGGAACCCGCACCGAATAGATGATGAACTGATGATGATAGACAACCTTATATAGCTCTAGACCATGTCATTCACCAGTTAGAAAAATCTTTGAAGACACACACTTTGTCCAGCATAGTTGTTGACAGCCCGGGGGGTGCAGGAAATGTATTTCCCCAAAACTGGCATTGGGGTAAAGTTGGTTTTATATTGGCACAATTACAATAATATAAATTCGGAAAAGTACTGTTTGCAAACTCTACATAGTGAAATCATATAATCAGCCAATGACTATAAAATACAACATCGTTTACTGTCAATAGT

Associated Phenotype:

Not determined