Busch Lab

ZMP

lrch2

Ensembl ID:
ENSDARG00000075580
ZFIN ID:
ZDB-GENE-080114-1
Description:
Novel protein similar to human and mouse leucine-rich repeats and calponin homology (CH) domain cont
Human Orthologue:
LRCH2
Human Description:
leucine-rich repeats and calponin homology (CH) domain containing 2 [Source:HGNC Symbol;Acc:29292]
Mouse Orthologue:
Lrch2
Mouse Description:
leucine-rich repeats and calponin homology (CH) domain containing 2 Gene [Source:MGI Symbol;Acc:MGI:

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa20480 Nonsense Available for shipment Available now
sa33655 Nonsense Available for shipment Available now
sa10513 Nonsense Available for shipment Available now
sa12170 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa20480
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112312 Nonsense 288 742 6 21
Genomic Location (Zv9):
Chromosome 5 (position 38799237)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 36598921
GRCz11 5 37199074
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGGATAAAAAGCCTGACACACTTGACCTGCCTTCTCTGGGAAAACGCTG[T/A]TTACCTCAGCAGCTGACTGACAGGTCCATACAGCCTTTTGCCATCTATTT
Long Flanking Sequence:
ATGATTCATACCCTTATAAAATCAGCCCCAATCGATCCTAATTAATGATTTCTTTCCAAATAGAGCTATACCACAATATATATTGCACAAAATCAAAATATCTCAATGTCAGATTTTTCCAATGTGTTGCAGCCCTAGTAAGAAACATCAGTAGTTTACAGAATGAAATAAAAAAAATTGCATTTGGCTCAAACACACAACCATAAATTGCAAATCCAGAAAAAAGTGAAAATTTCAAGTGGTCTCTTAAATCGTTCCACTCCTGTATTTCTTTGACATGTCTTTGATGAATAGAATTCAGTAAAAAAAAAAAAAGACAGCGGTTTTGTGACATCTCATCTTTTGTTAGTTTGTTAATTAATATATAATAATAAATATCTTTTTTGCTTTCAGATCTGCCTGAAGGGAAAGATCCACATCTTCAAGTATCTGAACCTGCAGGCATGTCGTCTGGATAAAAAGCCTGACACACTTGACCTGCCTTCTCTGGGAAAACGCTG[T/A]TTACCTCAGCAGCTGACTGACAGGTCCATACAGCCTTTTGCCATCTATTTATTGCGATTTCATCTACCAACAACACCAATTTTATAGCCCCAATGAATCATGTCATAAACACGTATTTCACAGAAATTCACAGAAACACTTTTTTACTCTTCCATTTTTTAATGTCACTGAAACCTTATCTACTTTTATCTATAATTCGTTGTTTCTGTTTATAGCTACATCATATTTTACATCATATATATGTTTGATTGGGAGCAATGTATAGCAGATGCTGACATGAGCCGGGTTACCATCCTCTGAAGCAAATCTTTTGAAAGTTCGCCAAAAAAGAAAAAATCTCAAATTTGAATGAGGTGTTTTTTTTCCCCCCAACGAGTTGTTAGAGCAGCTGACTGTAGTATTAGTAATCCAACAGTAAACAAGGCAAGCATAAAGCAGACAGGACTGCAGTTAGAAATGGTTGGGCAAGTTATAATTGTAAAGTATATATTCAAAAAGGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33655
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112312 Nonsense 337 742 8 21
Genomic Location (Zv9):
Chromosome 5 (position 38794074)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 36593758
GRCz11 5 37193911
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCTCCTGTTCCGCAGCCATCTGATGATGACACCATGAGTCTCCACTCT[C/T]AAGTGTCAGAAACGGCACGGGCTGACGCACACATTCTGCTCACAAAGCTT
Long Flanking Sequence:
ATTGAGAGTTTTTTTAGCCATTTAGTGGGATACTTAACCTGTACATCTTACACAAAGTACAAACTGTCACTCTTTTTTCACAAGGAAGTCTTCGCTCACAGAACAAAACAGGCATTCATTAAACTAAAACCTAGTGTGACTAATGAAATGAAAGTCTTGCACATTCACAGAAAAGATCTAATTTCCGCATTGCAAAATAAGGTGGATAGTACAAAGAAGATCTGTAAATACAAAGAATACTGTTTTTCACTTGATGAAAAAAGATACCACACGTTAGCACAAAAGCTCTTGAATAGTTGAGCTGGAAACACCAGTTGAGCATGACGAAAGATAATCTAGTAGGATGATCGAAGAATTTTGTTGTGGGAGTAAAACAACTGTCAATAATGTAAAGAGTTTTCCAGCAGGTGTGTCTTACAAAACAGACAAAAAAAAATCTTGTGTTTTCTCTTTCTCCTGTTCCGCAGCCATCTGATGATGACACCATGAGTCTCCACTCT[C/T]AAGTGTCAGAAACGGCACGGGCTGACGCACACATTCTGCTCACAAAGCTTGACTCAAACAAAGGTGTGTTTTCAGCATTAGTATTATTAACCATAAATAATTTTTCATAAAAGATGTTTTGTTGTGTTGTGTACCATAGTAATAACTTCATAATAGAAACTATACATTGAAACTAGACAAACAGATCTGTGTCAAACAGATACCTATATCATACCTATGTCAGTGTACAGATTTATGTCCTGATATGACACAAAAACACATACACACAGACACACACACACACACACACACACATACACACACACACACACACACACACACACACACACACACACACACATATGCACACAGTTAGGTCTATAAATATTTGGACATGGACACAATCGCAACATTTTTAGCTCTATACAACAGCACAATGGATTTGAAATGAAACAAACATTAAGTGCTTTAACTGCAGACTGTCAACTTTACTTTGAGTATCCAAATCAGGTGAACGTTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10513
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112312 Nonsense 394 742 10 21
Genomic Location (Zv9):
Chromosome 5 (position 38789436)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 36589120
GRCz11 5 37189273
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CACAAAMCCAGCCTGTAAAAGATCTTCCCATCTCTCCTTCACAGGAGCTG[G/T]AGCGGGTCCTGAAAACACACCAAAGCAAAGACAAAGAGAACTGGAAAGAG
Long Flanking Sequence:
ACGTTTTTTTCGGTGAGTTTTATTTTACCTATGATTGACACTGCAACTGATAATTACAGTTATAACATTTACTGACATGCTAATCCTATACAAAGTCTACACTCCCAGCAATCTCACAAAATGCAAAACAAAGCCATTTTCTCTTCTCAAGAAGTGTAGCATCTTACATAGCCGGTGTGTCTAGTAGGCAATTAAAATATCATTTTACAAGAATAAAACCGCCTTGTCTCAATAAGATCTCATTGTGTGCAGATCAGGACCCGTATGACTTTATTGACCCCAATCCAGATGAAGAGGGCACTTTGTCTGAGGGCGATCTACAGCACAATGCACCTTATGTGTCATGTATAAAGGTATGTATAAACACATAGACCCTTATCTACATCCTATCTTTACTGTTTTTTTTTGTCATGCAAAGCAATCCCCCACCTGAATCCATAGTTACTAAAACACAAAACCAGCCTGTAAAAGATCTTCCCATCTCTCCTTCACAGGAGCTG[G/T]AGCGGGTCCTGAAAACACACCAAAGCAAAGACAAAGAGAACTGGAAAGAGGAGTCAGGGTAAGTCCATGATGTGAGATATTATGCAGGAATTTCCCACAAGTTGCACAAATACTTCATCCCACCACCTTTAGATTACTTCTATTATCATCAATGACCTTGGTTATACATACTACAAGTTAAAAACGAGTGTTTACTTACTCTTTCTTTAAAAGTACTGTTTTAAAAGGACAATGAATTGCCATCTTCAATACTGAATCTTAAAGGTAACTCGTTATGGTCATTTTTACAAGATGTGAAGTTCCTATGTCCCTAGAGTGTGTATGTGAAGTTTCGGCTCAAAATAATTTTTATAAATCTTTGAAACTGCCCCTTTGAGGCTTTGTTCTAAATTGTGTTGTTTTTCTGACTATCACTTCAAATTTTAATGAGATTGTCCTCACAGCCCTCTTTTCAGAAGGGGATGGAGCTATAAACGCCTATGTGTCAACATAGTGGCAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12170
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112312 Essential Splice Site 632 742 19 21
Genomic Location (Zv9):
Chromosome 5 (position 38734805)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 36534489
GRCz11 5 37134642
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGAATGGCTAATTTGCAAATGAAACAAACAGAGCCCTTGTGTGTGTTTGC[A/T]GAACCTCGAGTCAAGGTTAAAGGKTTTAYTGCCAGATGACGTGGGCGCTG
Long Flanking Sequence:
TCAAATATTATTTGTTATTCTGACAAAATGTTCTTTCGTAAAAATTTACATTTGAAAGACATGTCATCAGACCTTTAGAGAATTAAACAAATATTTCAATTCTACCAAATCCCATATCTAATGAATAAAAAAAAACAAAAAAAAAACAAAACAGAGAAATTAACAATTTTATGATGATCTTTTAAATTAGTCTATAGCTGTAATTAGATTACTCATAGAAATGCATTTAGATTTACATGTGTGGTGGAGTGATGTGGGGTTGACTGATCCTAAAGCAGCCATGTCTAATCTCACATCTTCCTTCACTTCAGCTTCTGCATCTGCTCTCCTTGGTGCTGAAGAGCCACTCATGTGATGCCTGAATCTCTAAACAAAGCACTTACAGAGCCTTATCTTGACATTTAGCCTATGGGTGATTCTTTGTTAACGTGACATACTTACCTGTTATTTGGAATGGCTAATTTGCAAATGAAACAAACAGAGCCCTTGTGTGTGTTTGC[A/T]GAACCTCGAGTCAAGGTTAAAGGTTTTATTGCCAGATGACGTGGGCGCTGCGCTGATGGATGGTGTCGTTTTATGCCATCTAGCCAATCACATTCGTCCCCGTTCGGTCGCCAGTATTCATGTACCCTCCCCTGCCGTGGTAAGTCGAATATCCTATATCAATAAAGGATATTTACCTCAGAACTTCAGTCAAATAAGATTGTATTATGTTTGAGCTCTTTTAAATATTCATTAGTGAATTTACAGCATTCAAATCAAGCAGGATTTTGATTGTTGATGCTCTACTTGCTATAACTTTTATGTGTTTCTACTTTTTCTAATAGCCAAAGCTAAGTATGGCCAAATGTCGGCGCAATGTGGAGAATTTCTTGGATGCTTGTAAAAAGCTTGGAGTGCCACAGGTGGGATTGAGTGTCTCTTTCTTCTGAATCCATGATATTTTAACACTATATGGACTATTAGCCAATATCTCTATGTTTTTTTTTATTTATTTATTGGTA
Associated Phenotype:
Not determined