Busch Lab

ZMP

myhc4

Ensembl ID:
ENSDARG00000035438
ZFIN ID:
ZDB-GENE-030131-6206
Description:
myosin heavy chain 4 [Source:RefSeq peptide;Acc:NP_001018321]
Human Orthologues:
MYH6, MYH7
Human Descriptions:
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Mouse Orthologues:
Myh6, Myh7
Mouse Descriptions:
myosin, heavy polypeptide 6, cardiac muscle, alpha Gene [Source:MGI Symbol;Acc:MGI:97255]
myosin, heavy polypeptide 7, cardiac muscle, beta Gene [Source:MGI Symbol;Acc:MGI:2155600]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa31457 Nonsense Available for shipment Available now
sa20460 Nonsense Available for shipment Available now
sa20461 Nonsense Available for shipment Available now
sa31458 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa31457
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051362 Nonsense 661 1937 17 40
ENSDART00000077471 None None 105 None 4
ENSDART00000125917 Nonsense 659 1935 18 41
ENSDART00000131133 Nonsense 659 1078 18 25
Genomic Location (Zv9):
Chromosome 5 (position 33864879)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31627111
GRCz11 5 32227264
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTGAATACAAATCAGAAACTTTTCATGACTAAACAGGAGAACTTGGGC[A/T]AGCTTATGACCAACTTGAGGAGCACTCACCCTCACTTTGTGCGTTGTCTG
Long Flanking Sequence:
GCCTCAAAAAGGCAAGGCTGAGGCTCACTTCTCCCTGGTCCACTATGCTGGAACTGTGGACTACAACGTTAATGGCTGGCTGGACAAGAACAAGGATCCACTGAACGAGTCTGTTGTGCAGCTGTACCAGAAGTCTTCTGTCAAACTGCTGGCTACTCTCTACCCACCTGTTGTTGAGGGTAAAAAAAGTTTTGATATGATAATTTACATAAACTTAACCAAACTTAGATTTCCCCTTGTTATTACATTATGTAATCCTATGTATTTTTATATGAATAGAGACTGGCGGCGGAAAGAAGGGAGGCAAGAAGAAGGGTGGTTCCATGCAGACTGTGTCTTCTCAGTTCAGGGTATATTAATTCTATATCAATAAAGAAACAACTTAAAGTAGGCACTGTATATGACCTTGTTTTATTTTAGGTAAGGGAAATGATAAATAAAAAATTAAAAATGTGAATACAAATCAGAAACTTTTCATGACTAAACAGGAGAACTTGGGC[A/T]AGCTTATGACCAACTTGAGGAGCACTCACCCTCACTTTGTGCGTTGTCTGATTCCCAACGAGTCCAAGACTCCAGGTAATAAAATAAATGGCCTACAGGGGTACTGACATAAACACAATGTTTAATGTTTTTTTCCAAAATAATGTTAATAATTACCAAGCTCATGCTGTATAATTTTACAATTAGGTCTTATGGAGAACTTCCTGGTTATCCACCAGCTGAGGTGTAACGGTGTACTGGAGGGTATCAGAATCTGCAGAAAGGGTTTCCCCAGCAGAATCCTCTATGGTGACTTCAAGCAGAGGTAAATGGGACTTTATATAAACATGTAATTTATTTACTGTAAGAGTAATTTAATTAAAATTTATAAAGTATTTAATACATTTTCAACAGATACAAGGTGTTGAATGCCAGTGTTATCCCAGAGGGACAGTTCATTGACAACAAGAAGGCCAGTGAGAAACTCCTGGGATCTATTGATGTTAATCATGATGAGTACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20460
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051362 Nonsense 723 1937 18 40
ENSDART00000077471 None None 105 None 4
ENSDART00000125917 Nonsense 721 1935 19 41
ENSDART00000131133 Nonsense 721 1078 19 25
Genomic Location (Zv9):
Chromosome 5 (position 33865176)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31627408
GRCz11 5 32227561
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGAATCTGCAGAAAGGGTTTCCCCAGCAGAATCCTCTATGGTGACTTC[A/T]AGCAGAGGTAAATGGGACTTTATATAAACATGTAATTTATTTACTGTAAG
Long Flanking Sequence:
AGGGAGGCAAGAAGAAGGGTGGTTCCATGCAGACTGTGTCTTCTCAGTTCAGGGTATATTAATTCTATATCAATAAAGAAACAACTTAAAGTAGGCACTGTATATGACCTTGTTTTATTTTAGGTAAGGGAAATGATAAATAAAAAATTAAAAATGTGAATACAAATCAGAAACTTTTCATGACTAAACAGGAGAACTTGGGCAAGCTTATGACCAACTTGAGGAGCACTCACCCTCACTTTGTGCGTTGTCTGATTCCCAACGAGTCCAAGACTCCAGGTAATAAAATAAATGGCCTACAGGGGTACTGACATAAACACAATGTTTAATGTTTTTTTCCAAAATAATGTTAATAATTACCAAGCTCATGCTGTATAATTTTACAATTAGGTCTTATGGAGAACTTCCTGGTTATCCACCAGCTGAGGTGTAACGGTGTACTGGAGGGTATCAGAATCTGCAGAAAGGGTTTCCCCAGCAGAATCCTCTATGGTGACTTC[A/T]AGCAGAGGTAAATGGGACTTTATATAAACATGTAATTTATTTACTGTAAGAGTAATTTAATTAAAATTTATAAAGTATTTAATACATTTTCAACAGATACAAGGTGTTGAATGCCAGTGTTATCCCAGAGGGACAGTTCATTGACAACAAGAAGGCCAGTGAGAAACTCCTGGGATCTATTGATGTTAATCATGATGAGTACAGATTTGGACACACAAAGGTTCATTTTTGAATTTACAGTTTTATGAGATTCAGTGATCAGTGTAACTTAGATTAAACATCAATTTATTTTCCTTTTCTCTATTTAAATGAATTCAGGTGTTCTTCAAAGCTGGTCTGCTGGGTACTCTTGAGGAGATGCGTGATGAGAAACTGGCAACTCTAGTCACAATGACCCAGGCTCTCTGCCGTGCTTATCTGATGAGGAGAGAGTTTGTGAAGATGATGGAGAGGAGGTGAGGGAAAAGCATGAGTTATAATTGTGTGAATGGTAAAAAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20461
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051362 Nonsense 744 1937 19 40
ENSDART00000077471 None None 105 None 4
ENSDART00000125917 Nonsense 742 1935 20 41
ENSDART00000131133 Nonsense 742 1078 20 25
Genomic Location (Zv9):
Chromosome 5 (position 33865328)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31627560
GRCz11 5 32227713
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGTGTTGAATGCCAGTGTTATCCCAGAGGGACAGTTCATTGACAACAAG[A/T]AGGCCAGTGAGAAACTCCTGGGATCTATTGATGTTAATCATGATGAGTAC
Long Flanking Sequence:
AATGTGAATACAAATCAGAAACTTTTCATGACTAAACAGGAGAACTTGGGCAAGCTTATGACCAACTTGAGGAGCACTCACCCTCACTTTGTGCGTTGTCTGATTCCCAACGAGTCCAAGACTCCAGGTAATAAAATAAATGGCCTACAGGGGTACTGACATAAACACAATGTTTAATGTTTTTTTCCAAAATAATGTTAATAATTACCAAGCTCATGCTGTATAATTTTACAATTAGGTCTTATGGAGAACTTCCTGGTTATCCACCAGCTGAGGTGTAACGGTGTACTGGAGGGTATCAGAATCTGCAGAAAGGGTTTCCCCAGCAGAATCCTCTATGGTGACTTCAAGCAGAGGTAAATGGGACTTTATATAAACATGTAATTTATTTACTGTAAGAGTAATTTAATTAAAATTTATAAAGTATTTAATACATTTTCAACAGATACAAGGTGTTGAATGCCAGTGTTATCCCAGAGGGACAGTTCATTGACAACAAG[A/T]AGGCCAGTGAGAAACTCCTGGGATCTATTGATGTTAATCATGATGAGTACAGATTTGGACACACAAAGGTTCATTTTTGAATTTACAGTTTTATGAGATTCAGTGATCAGTGTAACTTAGATTAAACATCAATTTATTTTCCTTTTCTCTATTTAAATGAATTCAGGTGTTCTTCAAAGCTGGTCTGCTGGGTACTCTTGAGGAGATGCGTGATGAGAAACTGGCAACTCTAGTCACAATGACCCAGGCTCTCTGCCGTGCTTATCTGATGAGGAGAGAGTTTGTGAAGATGATGGAGAGGAGGTGAGGGAAAAGCATGAGTTATAATTGTGTGAATGGTAAAAAGTAATGATTATGGCATTTAATGATGAACTATTCACAGGGAGTCCATTTACACCATCCAGTACAACATCCGCTCATTCATGAATGTCAAACACTGGCCATGGATGAAGGTTTACTACAAGATTAAGCCTCTGCTGAAGAGTGCTGAGACCGAGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31458
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051362 Essential Splice Site 812 1937 21 40
ENSDART00000077471 None None 105 None 4
ENSDART00000125917 Essential Splice Site 810 1935 22 41
ENSDART00000131133 Essential Splice Site 810 1078 22 25
Genomic Location (Zv9):
Chromosome 5 (position 33865709)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 31627941
GRCz11 5 32228094
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTGAATGGTAAAAAGTAATGATTATGGCATTTAATGATGAACTATTCAC[A/T]GGGAGTCCATTTACACCATCCAGTACAACATCCGCTCATTCATGAATGTC
Long Flanking Sequence:
TAATTTATTTACTGTAAGAGTAATTTAATTAAAATTTATAAAGTATTTAATACATTTTCAACAGATACAAGGTGTTGAATGCCAGTGTTATCCCAGAGGGACAGTTCATTGACAACAAGAAGGCCAGTGAGAAACTCCTGGGATCTATTGATGTTAATCATGATGAGTACAGATTTGGACACACAAAGGTTCATTTTTGAATTTACAGTTTTATGAGATTCAGTGATCAGTGTAACTTAGATTAAACATCAATTTATTTTCCTTTTCTCTATTTAAATGAATTCAGGTGTTCTTCAAAGCTGGTCTGCTGGGTACTCTTGAGGAGATGCGTGATGAGAAACTGGCAACTCTAGTCACAATGACCCAGGCTCTCTGCCGTGCTTATCTGATGAGGAGAGAGTTTGTGAAGATGATGGAGAGGAGGTGAGGGAAAAGCATGAGTTATAATTGTGTGAATGGTAAAAAGTAATGATTATGGCATTTAATGATGAACTATTCAC[A/T]GGGAGTCCATTTACACCATCCAGTACAACATCCGCTCATTCATGAATGTCAAACACTGGCCATGGATGAAGGTTTACTACAAGATTAAGCCTCTGCTGAAGAGTGCTGAGACCGAGAAAGAGTTGGCAACCATGAAAGAGGACTTTGTCAAATGCAAAGAAGATCTTGTCAAGGCTGAAGCCAAAAAGAAGGAGCTGGAAGAGAAGATGGTGGCACTGCTGCAAGAGAAAAATGATCTGCAGCTGGCAGTGGCTTCTGTGAGTATTCTTAATTTAATAAAATCTCATCTCCATTAAAATTGGTTTGTTATGATTGAATGATGTGTTTTCCTAATAGGAAGCAGAAAATCTCTCAGATGCTGAGGAGAGGTGTGAGGGTCTGATCAAGAGCAAAATCCAGCTTGAGGCTAAACTCAAAGAGACAACCGAGAGACTGGAGGATGAGGAAGAAATCAATGCTGAACTGACAGCCAAGAAGAGGAAACTGGAGGACGAGTGCTC
Associated Phenotype:
Not determined