si:dkeyp-89c11.1

Ensembl ID:

ENSDARG00000069292

ZFIN ID:

ZDB-GENE-041210-201

Description:

Novel protein containing an Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransfer

Human Orthologues:

ACOT1, ACOT2, ACOT4, ACOT6, BAAT

Human Descriptions:

acyl-CoA thioesterase 1 [Source:HGNC Symbol;Acc:33128]
acyl-CoA thioesterase 2 [Source:HGNC Symbol;Acc:18431]
acyl-CoA thioesterase 4 [Source:HGNC Symbol;Acc:19748]
acyl-CoA thioesterase 6 [Source:HGNC Symbol;Acc:33159]
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) [Source:HGNC Symbol;Acc:9

Mouse Orthologues:

Acnat1, Acnat2, Acot1, Acot2, Acot3, Acot4, Acot5, Acot6, Baat

Mouse Descriptions:

acyl-CoA thioesterase 1 Gene [Source:MGI Symbol;Acc:MGI:1349396]
acyl-CoA thioesterase 2 Gene [Source:MGI Symbol;Acc:MGI:2159605]
acyl-CoA thioesterase 3 Gene [Source:MGI Symbol;Acc:MGI:2159619]
acyl-CoA thioesterase 4 Gene [Source:MGI Symbol;Acc:MGI:2159621]
acyl-CoA thioesterase 5 Gene [Source:MGI Symbol;Acc:MGI:2384969]
acyl-CoA thioesterase 6 Gene [Source:MGI Symbol;Acc:MGI:1921287]
acyl-coenzyme A amino acid N-acyltransferase 1 Gene [Source:MGI Symbol;Acc:MGI:2140197]
acyl-coenzyme A amino acid N-acyltransferase 2 Gene [Source:MGI Symbol;Acc:MGI:2444345]
bile acid-Coenzyme A: amino acid N-acyltransferase Gene [Source:MGI Symbol;Acc:MGI:106642]

Allele Name	Consequence	Status	Availability
sa10802	Nonsense	Available for shipment	Available now
sa20291	Nonsense	Available for shipment	Available now
sa7319	Essential Splice Site, Missense	Mutation detected in F1 DNA	Not yet available
sa16197	Nonsense	Available for shipment	Available now

Allele Name:

sa10802

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

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Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100693	Nonsense	26	229	2	6
ENSDART00000100714	Nonsense	63	450	3	14
ENSDART00000100717	Nonsense	84	470	3	12

Genomic Location (Zv9):

Chromosome 4 (position 24742630)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	25666299
GRCz11	4	25655497

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TCATAAAGAATTTACTGCCAAATCAAGAGGTAAYGCTRCACTCTCTACAT[C/T]AGTCTGAAGATARGGACTKCTGGGAGGCTTTTGGACACTATATYAGTGAT

Long Flanking Sequence:

GGATGCATAAACAGCCACCGATTTTTTTAAAAAGTTGCCGTTCTTGCCTACTGTACATATTACTTCTGAAGCAAGGTTAGTGAGTGAAAAACAAACCAAAATTGTTGAAACAATGCATTATTCAATGAAAATCTTAACATCCACATATGTTGGCGTGCTCATTTGCTTTATGTTTCTGCATTTTAAATAATTTTTATTTTAACTATTCATTTAATTTACTTTTTTTGCCTTAAACTTAGTTTTGAGATATAATATTATTTATATCTGCCACTCAACTATAATGCGAATAGACGTGAATTCCTAAAAGTGGTATATAATTGGGAAAACAAGACATACACGTTGCTGTCTTTCATTTATTTGTCTCTAGAACTGTGAGCACTGAAAGTAGGAGATGTCCTCTGTTAACTGTTCAGCCATGTCGAGGAATGGTGGACGAGAAGTTTCAGGTCGTCATAAAGAATTTACTGCCAAATCAAGAGGTAACGCTACACTCTCTACAT[C/T]AGTCTGAAGATAAGGACTGCTGGGAGGCTTTTGGACACTATATCAGTGATGAACATGGAACAGTAACAGGTGTGTACGACTTTTTGATACATAAAAAATACCACTGTAGACATCTCCGACATACTGTAACATAGACATAAATTCTGATTAAACACTTCACACCTTTCTCTTTCAAAACCTTATCCACTTACGACTCTATCTCAGATTGTCTCCATTGACTGCTTGTATAAAAATGACTCATTTTTACAGTTACAGTAGTAGGTACAGAACTGGCTCATATTCTGCACAGAAGATGATGATAAAGAACTTGCTTTGACAAACTAAAGATAATATGAAATTAATTTTAGCTGAATGTTCCTGCTGGGTACCAAAATGTACAATGCACAGATCTATCTATTAAAATTAAGGATTAAACATTAATAAACTAAAACAATGGTTCAAAATCCATGTATGACCTTATGACTACATGTATCCTGCTGAAATAGTGGCAAAAGATGAAA

Associated Phenotype:

Not determined

Allele Name:

sa20291

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

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Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100693	Nonsense	141	229	4	6
ENSDART00000100714	Nonsense	178	450	5	14
ENSDART00000100717	Nonsense	199	470	5	12

Genomic Location (Zv9):

Chromosome 4 (position 24743554)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	25667223
GRCz11	4	25656421

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACCAGGTGTACAGAGGGTGGACATAAGAGAGAACGGAGTTCAAGGAACTT[T/A]ATTTCTTCCCCCAGGTAAAATACGATTCATGCGATATTTAAGTTCACATA

Long Flanking Sequence:

ACTAAAACAATGGTTCAAAATCCATGTATGACCTTATGACTACATGTATCCTGCTGAAATAGTGGCAAAAGATGAAAGTTTGGGAGGCACATATGAAGGGACAGAGCAGATGGGTTTGTTGTGGAGCCTGAGGCCTGTACCAGGAAGTCGACCTGCAATCAGGTACAATAAGTCACTGTAAAATGATGGTGGTTTTACTGTAGTCTGTTTTATAAAGTTTAAATACCATTTTTTCTAAAAAAAATAAAAAAAAAAAAAGTGAAGCCAAAGTCATTATTTTTATTTATTCCTACACTTTTTGTCCTTCATCTCTTTTTATTTAAGGTTGCGCAAAACGAATTTACTCACACCAATGGTAGTTAATATATCAGTCTACAGTGGGCATACTTCTCAAGGATTCAGTCAGACTTCAGCGCTGGCCACTACTGTCACAGAGCGCTGGTACATGGCACCAGGTGTACAGAGGGTGGACATAAGAGAGAACGGAGTTCAAGGAACTT[T/A]ATTTCTTCCCCCAGGTAAAATACGATTCATGCGATATTTAAGTTCACATAAAAATTTAAATATCCCTCTTTAAAAGATGTCTGATTTATTTATTTGTATAGTTTTTTTATACAATACAACTTTTACGGTACCTTTTCCAAAGGGTACCAAAAAAAGAAGAGCTAGACACGCAGCTGAACGCTATTGGTTTACAGAGAACTTCACTAGTGTGTACACAAGCCATGAGAATGAAAACAAAGGAAGTGCTATTTTTAAATACTCAGCCGAGATATTACACCGTAATATATATAATAACGAGCCATGGTTGACCCGAGTTCAAACTAGTTGGTTGGGTGAAGTACCAAAACCCAGACTTGCTTTTTTCTTTCTTGTTTTTTTTTTTTTTTTGACACTTAAATGACAGAGCTGTCAACTGAAATAAGGGGTGTGTGTTTTTTGTTTTGTTTTGTTCTTGTTTTAAGAATAATTTTAAGGACTGATTTAACATAGCAAGTTATTGC

Associated Phenotype:

Not determined

Allele Name:

sa7319

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site, Missense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100693	None	None	229	None	6
ENSDART00000100714	Essential Splice Site	401	450	11	14
ENSDART00000100717	Missense	423	470	11	12

Genomic Location (Zv9):

Chromosome 4 (position 24749109)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	25672778
GRCz11	4	25661976

KASP Assay ID:

554-4479.1 (used for ordering genotyping assays)

KASP Sequence:

CTGGTCATTTGATTRAACCTCCATACACACCTCACTTCAGAGCAACTAAY[G/T]TYCTCCTGCATAAAAAGGAGAAAGGCAAGCATACATGATCCATTCYATTG

Long Flanking Sequence:

TCCAACATTCTTTCAAATATTGGCTTTTCTAATCAAAGTAAACAAAAAAAGGGGGCAGGGGCAGGGGCTCGTAGTTGAAGGGGGGGGGGGGGTGATGTGATCAGAAAGTGAAGGGGGAGGGTTGAATTAAAGTTTGGTAAATTTTGGTATAAAAAACTTTTTATATTTCAGCATTGTTTCCTCTGCTAGATCACAGAAATATCCTCACTGGAACCCTTTAAAACTTTTAATCCCAATGGCATTTAAGCAAAATGTTAAACTTTTTTTAATTTTTCAAATTCATTGTTAAGGGTTTTTTTTTACTCACCCACGGAAATTACCTTTAAATAGCAGTGTAGTGTTCTCACCAATGACATAGAGCCTTGATATGATTCATTTACGCACAGATTGAGATGATAATGGAGAAAGCAGGAAATCGGCACCTGCTGACTGTCTTCACATACCCTGACGCTGGTCATTTGATTGAACCTCCATACACACCTCACTTCAGAGCAACTAAC[G/T]TCCTCCTGCATAAAAAGGAGAAAGGCAAGCATACATGATCCATTCCATTGTTGCCTTCTGATTGTATTTTTCATATCCACCTTTTTCCTCACATGACTGCTTCGTTTAAATTATGAGCTGCACTTCCAGACAGGGGAACATCCATTCCACTTAAACTTATCTTTTAAAATAATAAGGCTGTGTTATAATATTCAATATGATATAAGGCTGTAGTTACACGATAATGAGGTAGCAAAAAATGGAATAGTTTTTGCGTTTTTACAGTTTCTCGTATGCACAACATTTTACAGATAATCTGTGTTTACAAATATCAGCACAGGGGATTGGTATGTATTTAGATTTTGCCTGTTATAAATAAAGTGTGTCACAATCACCAGCGATCTAATCCTTGCAGATCACTGGTAAACTCACAGATAGTATAGAACTACAAATCTACCGGTATATGGACTACAAGATCCAGTCAAACACACACCTGCTGCAAGTCTCCATTGATTAGAATC

Associated Phenotype:

Not determined

Allele Name:

sa16197

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
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Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000100693	None	None	229	None	6
ENSDART00000100714	None	None	450	None	14
ENSDART00000100717	Nonsense	427	470	11	12

Genomic Location (Zv9):

Chromosome 4 (position 24749121)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	25672790
GRCz11	4	25661988

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TTRAACCTCCATACACACCTCACTTCAGAGCAACTAAYKTYCTCCTGCAT[A/T]AAAAGGAGAAAGGCAAGCATACATGATCCMTTCYATTGTTGCCTTCTGWT

Long Flanking Sequence:

TCAAATATTGGCTTTTCTAATCAAAGTAAACAAAAAAAGGGGGCAGGGGCAGGGGCTCGTAGTTGAAGGGGGGGGGGGGGTGATGTGATCAGAAAGTGAAGGGGGAGGGTTGAATTAAAGTTTGGTAAATTTTGGTATAAAAAACTTTTTATATTTCAGCATTGTTTCCTCTGCTAGATCACAGAAATATCCTCACTGGAACCCTTTAAAACTTTTAATCCCAATGGCATTTAAGCAAAATGTTAAACTTTTTTTAATTTTTCAAATTCATTGTTAAGGGTTTTTTTTTACTCACCCACGGAAATTACCTTTAAATAGCAGTGTAGTGTTCTCACCAATGACATAGAGCCTTGATATGATTCATTTACGCACAGATTGAGATGATAATGGAGAAAGCAGGAAATCGGCACCTGCTGACTGTCTTCACATACCCTGACGCTGGTCATTTGATTGAACCTCCATACACACCTCACTTCAGAGCAACTAACGTCCTCCTGCAT[A/T]AAAAGGAGAAAGGCAAGCATACATGATCCATTCCATTGTTGCCTTCTGATTGTATTTTTCATATCCACCTTTTTCCTCACATGACTGCTTCGTTTAAATTATGAGCTGCACTTCCAGACAGGGGAACATCCATTCCACTTAAACTTATCTTTTAAAATAATAAGGCTGTGTTATAATATTCAATATGATATAAGGCTGTAGTTACACGATAATGAGGTAGCAAAAAATGGAATAGTTTTTGCGTTTTTACAGTTTCTCGTATGCACAACATTTTACAGATAATCTGTGTTTACAAATATCAGCACAGGGGATTGGTATGTATTTAGATTTTGCCTGTTATAAATAAAGTGTGTCACAATCACCAGCGATCTAATCCTTGCAGATCACTGGTAAACTCACAGATAGTATAGAACTACAAATCTACCGGTATATGGACTACAAGATCCAGTCAAACACACACCTGCTGCAAGTCTCCATTGATTAGAATCTCATAGCTGATT

Associated Phenotype:

Not determined

ZMP

Alleles

Mutation Details

Mutation Details

Mutation Details

Mutation Details