ZMP
ppp1r12a
Ensembl ID:
ZFIN ID:
Description:
Protein phosphatase 1 regulatory subunit 12A [Source:UniProtKB/Swiss-Prot;Acc:Q6DRG7]
Human Orthologue:
PPP1R12A
Human Description:
protein phosphatase 1, regulatory (inhibitor) subunit 12A [Source:HGNC Symbol;Acc:7618]
Mouse Orthologue:
Ppp1r12a
Mouse Description:
protein phosphatase 1, regulatory (inhibitor) subunit 12A Gene [Source:MGI Symbol;Acc:MGI:1309528]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20272 | Essential Splice Site | Available for shipment | Available now |
| sa25279 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa15933 | Nonsense | Available for shipment | Available now |
| sa20271 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa20272
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008940 | Essential Splice Site | 521 | 1049 | 11 | 26 |
| ENSDART00000033825 | Essential Splice Site | 521 | 1030 | 11 | 28 |
| ENSDART00000123424 | Essential Splice Site | 521 | 623 | 11 | 13 |
| ENSDART00000132923 | Essential Splice Site | 589 | 1117 | 11 | 26 |
Genomic Location (Zv9):
Chromosome 4 (position 20453608)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 21796943 |
| GRCz11 | 4 | 21517918 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACCGAGGAGACATGTTAGCACCTCAGACATCGATGAGAAGGAAAACAGG[T/C]AAAGAGAGCTTTGTGTTGTTAAGAGCGCCTCCTGCTGCTCTGTGGGCTGT
Long Flanking Sequence:
ATTATTATAATTTTTTTTAATTCAGTGTTTTTAATGTGTAAAATATAAATAGTAATAATAAAAATATGTAGAAGCAAAATAATTGGTTACTTTATTTTAATATGTTCTTGTCACAGTGTGAATATTTAACTACTGAGTATTAATAATTAACTACACATAGTTACTGAATGGTTAGGGTTAGAATGTTTAGCATGTTATTATGCATATTTGTTATTACTATAGTAAGTACATGGAACGTGGCAAGGACACCTTTAAAGTGTTAACAAATCATTTTTTAGATTAATTTTCTGCTTGATTTACATTGTTTTGATTTATATATATTGTATATTGCTTGATTTATATCTTTTCATAAACATTTTGAAGATTGGAGCTGTTTGTCATCTCATACTAGCTTGGTTTATTTACAACAGGAGAAGGAGAAAACACGCCTGGCATATGTTGCACCAACTATACCGAGGAGACATGTTAGCACCTCAGACATCGATGAGAAGGAAAACAGG[T/C]AAAGAGAGCTTTGTGTTGTTAAGAGCGCCTCCTGCTGCTCTGTGGGCTGTGTTGCAGTGTGAGGAGAATTACTCTACACACATTCAGATTACAGGAGAGATGAATATCACTGTCAAATATTTATGTCTTTTTCCAGTTGTGTAAAGTTAAAGGAAAGGTTCGTTCAAAAATAAAAAACATTTACTCACCATTTAGTCACACCCATGTGGCTTTAAACTTTTATGATATTATTTCATTTGTTAAACATGAAATAAGATATTCTGAAAAATGTTGGGGGGAAAGCACTATAGTCTAAACTGCCCTCTAACATTCTTCAGAGTTTTTTTTGTTTGTTTGTTTTTTTACAGAGGAAAGAAACTTAAATGGGTTTGGATTAGTAAATAATGACAGAATTTTCATTTTTAGAGTGAAATATCCCTTTAAGTTTGTTAGTGGAATAAATTTACATTTTTTAATGTATTTATTTGACAAGGACTTGAAATCGACCTAGAACATAGCAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa25279
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008940 | Nonsense | 708 | 1049 | 16 | 26 |
| ENSDART00000033825 | Nonsense | 708 | 1030 | 17 | 28 |
| ENSDART00000123424 | None | None | 623 | None | 13 |
| ENSDART00000132923 | Nonsense | 776 | 1117 | 16 | 26 |
Genomic Location (Zv9):
Chromosome 4 (position 20445840)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 21789175 |
| GRCz11 | 4 | 21510150 |
KASP Assay ID:
554-7423.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTTTGTGTGTGTAGATCGTACCTCACTCCAGTACGAGATGAAGAATCT[G/T]AGTCTCAGAGGAAAGCCAGATCCAGACAGGCACGACAGTCCAGGAGATCT
Long Flanking Sequence:
TCCAAAATACATGTTTAGATGTTTCATTCATTTATTCAATTTATGTCTGTTAATTTATAATCACAATATATATTTAAATGCTTTTTTCTCAAATAGTTTTTAACATATTTTTTACATTTCTGTTACAAAGTGAATATTTGTTGTACTTATTTATTTGGTTCTTAATTAAAATGACAATAAACAACACGACATTCCATAACACAACCTAGGCAATAAGTGTGCAATCTGAACATCATTTTAGGAAAATTACGATAGTCAACAGAAAGCTTGCAAAGTACTTTTATGATTTGTACCAAGATTTGCTGATCATTAAACAACACATTGTTTTGTAGTTTCTAATAAAGTGGAAACTTTCCTACACATTCTTCCAAAGCCTTTTTTTATGAAAACTGCTTGAACATAAGCATGTGTTGCTTCAGCTGTGTTTAACCTGCAGGGCTGTGTGTGTGTGTGTTTGTGTGTGTAGATCGTACCTCACTCCAGTACGAGATGAAGAATCT[G/T]AGTCTCAGAGGAAAGCCAGATCCAGACAGGCACGACAGTCCAGGAGATCTACACAGGCAAGTCTAGACACTCATCTAATAATAGACACAAGTGCAGAACAGTTTACAAACCATTGGAAGATTTTATTGGGTTTAGCTTCAGCTTTTTAGTTTATTATAAACCAGGGTTTTGAAATGTGGTGGGAAACTATTGGACAAATTAGTGTTTATAATAGAGGAGAGATTGACCAGAAGCTTTAAAGAAAAATCACTAACTAAATGTAATAATTACCAGCTCTAAAAAACCACTATAAACATTACATTATACATGATTTACTTGTGTGTTACGTTATCATGTGGTAAGACCTATTTTTAGATAATGTAGGTAGTTAAATGTTTAAAATGTGAATCATCTTCCATCTTTATTGTACTTTTAGTTTTAATTCAATAAGTCTAATTATATTCATATTATTATTATTATGATTATCATTAATAATACAGATTGAAATTTACAACATCAGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15933
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008940 | Nonsense | 720 | 1049 | 16 | 26 |
| ENSDART00000033825 | Nonsense | 720 | 1030 | 17 | 28 |
| ENSDART00000123424 | None | None | 623 | None | 13 |
| ENSDART00000132923 | Nonsense | 788 | 1117 | 16 | 26 |
Genomic Location (Zv9):
Chromosome 4 (position 20445804)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 21789139 |
| GRCz11 | 4 | 21510114 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGATGAAGAATCTGAGTCTCAGAGGAAAGCCAGATCCAGACAGGCACGA[C/T]AGTCCAGGAGATCYACACAGGCAAGTCWAGACRCTCATCTAATAATAGAC
Long Flanking Sequence:
CAATTTATGTCTGTTAATTTATAATCACAATATATATTTAAATGCTTTTTTCTCAAATAGTTTTTAACATATTTTTTACATTTCTGTTACAAAGTGAATATTTGTTGTACTTATTTATTTGGTTCTTAATTAAAATGACAATAAACAACACGACATTCCATAACACAACCTAGGCAATAAGTGTGCAATCTGAACATCATTTTAGGAAAATTACGATAGTCAACAGAAAGCTTGCAAAGTACTTTTATGATTTGTACCAAGATTTGCTGATCATTAAACAACACATTGTTTTGTAGTTTCTAATAAAGTGGAAACTTTCCTACACATTCTTCCAAAGCCTTTTTTTATGAAAACTGCTTGAACATAAGCATGTGTTGCTTCAGCTGTGTTTAACCTGCAGGGCTGTGTGTGTGTGTGTTTGTGTGTGTAGATCGTACCTCACTCCAGTACGAGATGAAGAATCTGAGTCTCAGAGGAAAGCCAGATCCAGACAGGCACGA[C/T]AGTCCAGGAGATCTACACAGGCAAGTCTAGACACTCATCTAATAATAGACACAAGTGCAGAACAGTTTACAAACCATTGGAAGATTTTATTGGGTTTAGCTTCAGCTTTTTAGTTTATTATAAACCAGGGTTTTGAAATGTGGTGGGAAACTATTGGACAAATTAGTGTTTATAATAGAGGAGAGATTGACCAGAAGCTTTAAAGAAAAATCACTAACTAAATGTAATAATTACCAGCTCTAAAAAACCACTATAAACATTACATTATACATGATTTACTTGTGTGTTACGTTATCATGTGGTAAGACCTATTTTTAGATAATGTAGGTAGTTAAATGTTTAAAATGTGAATCATCTTCCATCTTTATTGTACTTTTAGTTTTAATTCAATAAGTCTAATTATATTCATATTATTATTATTATGATTATCATTAATAATACAGATTGAAATTTACAACATCAGTGCAAAATCAGCTTTTTATTATGCAATTTTATTTAAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20271
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000008940 | Essential Splice Site | 1021 | 1049 | 25 | 26 |
| ENSDART00000033825 | Essential Splice Site | 1002 | 1030 | 27 | 28 |
| ENSDART00000123424 | None | None | 623 | None | 13 |
| ENSDART00000132923 | Essential Splice Site | 1089 | 1117 | 25 | 26 |
Genomic Location (Zv9):
Chromosome 4 (position 20432096)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 4 | 21775431 |
| GRCz11 | 4 | 21496406 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAAGAGCTCTAGAAAGGAAGATCTCTGAGATGGAGGAGGAGCTGAAGG[T/A]AATTATGTTCTGCCCTTTGCTGTGCGTGTGGGTCACCATTATAAAACCAC
Long Flanking Sequence:
CTATTGTACTTCTACTACCACTACTAATAATAATTGACATTAATTATTCCTGAAACCTACACAATAGTTTTTACTTATTTTAAAACTGAATAATTGTATTACTTTAACAACTTTTCCTAGAATCTGTTTTATATGACTATAATTATATTAATACATGGGTAATTTAATTATAGTATAATATTAAATTCTAATATTTTTTTTATTAATAATAGAATGTTCTCAGAGCAGGTGTGAGCATGAGTAAACCAGACTGTATTTCTGCTCCACTAAGCAGTGTGTGTGGTTCTTTTCACCTTAATCACTTCCTTTAGTTTTGACGTTCATTCACCTGATGCCTCCACACGATTCTGTGTGTTTCTCTCTGTTTGCAGTGCTAGTGGATCATACAGTTGTGTATGTGTGTTTTATGGTCATTTGCTTGAACTTGTTAATGTTTGTGTGTCTGCAGGAAAGAAGAGCTCTAGAAAGGAAGATCTCTGAGATGGAGGAGGAGCTGAAGG[T/A]AATTATGTTCTGCCCTTTGCTGTGCGTGTGGGTCACCATTATAAAACCACTAAAATAGAAAATCTGTTGTTGTTTTTATTCATATTTTTTTTTCAAATGTTTATGTGATTTTTAAATCTGTTTTGGCCTGTTTTCTGTCAAAATGTTTGTTAAAATGTGTATTTGTTATGAATACAGTCAAATATAGATGATCTTAAAGTAACTAATAGACTAAAAGCTATAAAAATAGTTTTGTCTGGTTTGTAACTTCATTTGATTGTGATTCTGGTGTGACTGCAGTTAATGTTAAAAGCATGAAGTGGGAGCAGAAGTTTGTGTGGACTAGATTTTTTCAGACTTTGCTTTTTTTTGTTATTGTTTTATTTTTGCAACATTTTTCTTATTATTTTAGCATTTATCACTGAATTCACTCCAGTTAAGTATGGGAGTTTGTGTTTATTTCCAATTTTAGGATACATTTTCTTCATTATTAAACAAAATGTTTGACAGCTGGTAATGTT
Associated Phenotype:
Not determined