Busch Lab

ZMP

cacna2d4a

Ensembl ID:
ENSDARG00000026855
ZFIN ID:
ZDB-GENE-041210-213
Description:
Novel protein similar to vertebrate calcium channel, voltage-dependent, alpha 2/delta 3 subunit (CAC
Human Orthologue:
CACNA2D4
Human Description:
calcium channel, voltage-dependent, alpha 2/delta subunit 4 [Source:HGNC Symbol;Acc:20202]
Mouse Orthologue:
Cacna2d4
Mouse Description:
calcium channel, voltage-dependent, alpha 2/delta subunit 4 Gene [Source:MGI Symbol;Acc:MGI:2442632]

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa15879 Essential Splice Site Available for shipment Available now
sa31396 Nonsense Available for shipment Available now
sa20268 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa15879
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048023 Essential Splice Site 193 1091 6 39
ENSDART00000136069 Essential Splice Site 142 743 4 24
Genomic Location (Zv9):
Chromosome 4 (position 19225939)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 20569274
GRCz11 4 20290249
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AATACGCAGCAAAGCGWCGTACAAGTGCCCACAAATGTTTATAAYAAAGG[T/C]ACGTGCCATAAGTGATATTTTACCCCTTAATTAGGAACTGAACATAAAGC
Long Flanking Sequence:
ATGGTGAAGGAATTTGCTGAGGAAATGGAGAACATGCTGGGCAGAAAAATGAAATCAGTTAAGGTCAGATATTTCAATGTTTTGTAATAATTACTATTGCACTAAATAATCATTTCGTTTATTTGTTGAAAGCTTTTTTTAATATAAGAGTGATTTAAATTTTTTTTTATTTCATGTCATTTATAGAGAATGGCAGAGACAGCAGAAGACGCAGATTTTTATCATGAATTTAATGCCACATTAGAGGTGAGTTATCCAGCAGTCCTTCGATCGATCTCCCTCACCTCCATTCATTTATTATTATACATTTAATTTTTCCTGCTTTTACTTTTGCAGTTTGACTACTACAATTCCATGTTGATTAACACATTAAATGAAGATGGAAACAACATAGAGCTGGGGGGTGAATTTCCTTTGGAGGAGAATGAACACTTCAACAATCTGCCTGTCAATACGCAGCAAAGCGTCGTACAAGTGCCCACAAATGTTTATAACAAAGG[T/C]ACGTGCCATAAGTGATATTTTACCCCTTAATTAGGAACTGAACATAAAGCTAATCTTTCCTTGTCACTTAGATCCTGATATCCTGAACGGGGTGTTTATGTCAGAAGCACTGAATGACATATTTATCAGTAACTTTGAGAAGGACCCGACTCTAACCTGGCAGTACTTCGGCAGTTCAACTGGATTCTTTAGACTTTACCCAGGTAATCAGAACAAAAACAGCCTTACCACTTCAAATTCACCAGTGCAGTGTACCAAACATGTACATTTGCTCATTCACACACAGAGAGCTGAGAGTCTGATTGACAAAGTGTAATTACTGGTGTAATTACTGGTGACAGTGACTCAGGCTTTTCTATCTGCCTCTCTCATTCATCATCATGTCTTCTGAGTACACACACAGAAACCAAACCAAAAAACTCAGGCTCTCCGCATCAAACAAGAATTCTCTCTAAAGGAAATATTTTTATATATTTTTTCTAAGGTATTAAGTGGACACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31396
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048023 Nonsense 522 1091 16 39
ENSDART00000136069 Nonsense 466 743 14 24
Genomic Location (Zv9):
Chromosome 4 (position 19210062)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 20553397
GRCz11 4 20274372
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGTGGTTGGCACTGATGTTCCCTTGAAGGAGCTCATGAGATTGGCTCCT[C/T]GATACAAGGTGCCTTAATAATATCATCAGTTCTCTGTTGATCACATCTAA
Long Flanking Sequence:
TTTTTTACATTTTATAATGAACTTATTACAGTAAAAACTAAATTTCATTTATAACAGAATTACACTAGTTTTTGCCTTGATTTGCTTGCCGATGTTTTCTGCATTAGTCCTCTCTATTCATCGAGTGACAGGATTTGCATTTAAAAAAAAACTGATTAATTTACAACATTAAATTGAAACATTTCTTTTCAATTAGCTTTTTTGTAGCTCAGCAATAAAAAAAATAAAAAAGGTTACGTCAAATTACGTCAGTACATCAATCTCATTCTCCTCTCAGATGGGATGGTGGGCCAAATCAAAGGTTACAATTGGCTAACTTTGGCTTTGGTGAAATTTGTAGTAAAACCATGGTTAAATTCCACTAGAATACAGACTGAATGAGAATTTGTATTCAAAATGTAAATTTTGTTCTTTTTCTCACTGTGCAGCTCTCTCATGGCATCCTCCTCGGTGTGGTTGGCACTGATGTTCCCTTGAAGGAGCTCATGAGATTGGCTCCT[C/T]GATACAAGGTGCCTTAATAATATCATCAGTTCTCTGTTGATCACATCTAACTCTTTTCCATTCACAGAACAGACTGTGTCCATGGAGATTATTGCATACAGAGTGACTGATTGTTTAGACACCAGACTGAATAATAAATATGTGATTTTCCTGAATGATTTATTCTGATTTTTTTTCCATTCTCATTTCAGCTGGGGGTTCACGGCTATGCATTCTTAAACACTAATAATGGTTATATACTCTCTCATCCTGACCTTCGACCTCTGGTGAGCAGCTGCATACATTCCCTTTAGAGGTCTTTTGACTTACTATCATAATTTGCTGTTAATTTAATCACTTTCACACCATCCAAAATATAGGTGTTTGTTTTTTCCTCTTTGATAGAAATTTGAAGAGGCATTTAGCTAAAACATGATGCTTAATGATTCATAAAATAAGTCAATAGCACTTTGAGAGTCAGAAAACTATATTTAGGCAAAATAAAATTAATACCACTCAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20268
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048023 Essential Splice Site 882 1091 30 39
ENSDART00000136069 None None 743 None 24
Genomic Location (Zv9):
Chromosome 4 (position 19181674)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 20525009
GRCz11 4 20245984
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGTCATTGACAGTAATGGCTTCATCATCATCTCTAGGGACAAGGCTGATG[T/C]AAGAGCACTTAAAGTGACAGGTTAAGGCCAAATTAAAATGACATTCGCAA
Long Flanking Sequence:
GCCTGTGCAGATCATGTGATGGCTTAAAGGCAGAACAGTGATTTTATAAGCAGGAGTTTAGATCAAAGCTATCAGTCCTGAGCCAGTGATTTCACATCAATTAACATTTTACCATTTTTTCTCTGCTGCTTCATTTTATCCGGATGACCCTTAGCCGAACGACACAGATGTATGTACGCATTACAAGGATAAACATGATACCATAAAAACGGAATACATATAAATGCTCAGTTTCTCCATCTTCATGATTTTCTGTCTTTTTTTACAGTGTTCAGGCATAGAGGGGCTTTGTCCTTTAAGCTGTAGTGATAATCCGGTGAGCATCTTATTGCAGTTATAGTGCATAAGTTGTGGGTATCAAGATTACAGGCATATGTATGAAAATATGTTTTGCCATTCCTCATTTGAGCATGACGTGTTTTTTTTTTCTCAACAGGACATTAGCTGCTACGTCATTGACAGTAATGGCTTCATCATCATCTCTAGGGACAAGGCTGATG[T/C]AAGAGCACTTAAAGTGACAGGTTAAGGCCAAATTAAAATGACATTCGCAACCCACCAAACATCCGTAATGACGTAAAATGATTTATTTTCAAATGAAACGATATCCATTTAGAAACATGTAGGGCAAGATTGAATTTTTATCTTTTCAGCTAATTGATCGGACTGTGAAAATGGCTGATATACATCAAAATAAAGCCACATTTTAATGCAAGTAAAACTGTTGTTTTACTCTTAATTACATTAATCAATAGACAGTGTAACCAAAATGGCTTTAGTAGAAATGCAGCGCACTTGCAAGTTGTATTAGGGTTTTTATTTCTACATATTTGCTTTTTTAGAACAGTGCCTATGCAGTTAGCCTTTGCTAGACAAGGTTGTAGATTTTCATAACATGAAGGTCACCTTAAAACTGCCAAAAATACAGCAAAAAGTGTGATCAAGCTAAGTAGGTTAACTGTGTGTACTGTATATGTGTATATAAAATGAGATTTACTGAGGTA
Associated Phenotype:
Not determined