Busch Lab

ZMP

lamc1

Ensembl ID:
ENSDARG00000036279
ZFIN ID:
ZDB-GENE-021226-3
Description:
Laminin subunit gamma-1 [Source:UniProtKB/Swiss-Prot;Acc:Q1LVF0]
Human Orthologue:
LAMC1
Human Description:
laminin, gamma 1 (formerly LAMB2) [Source:HGNC Symbol;Acc:6492]
Mouse Orthologue:
Lamc1
Mouse Description:
laminin, gamma 1 Gene [Source:MGI Symbol;Acc:MGI:99914]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa379 Essential Splice Site Available for shipment Available now
sa19814 Essential Splice Site Available for shipment Available now
sa9866 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa379
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004277 Essential Splice Site 325 1593 5 28
Genomic Location (Zv9):
Chromosome 2 (position 35675287)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 35971997
GRCz11 2 35954454
KASP Assay ID:
554-0359.1 (used for ordering genotyping assays)
KASP Sequence:
AATATTTTTTATAGGCACATTTTCTGACTGGTGTTTGTGTGTGTGTTTCA[G/A]CTTGTAACTGTAATGGAAAGAGCGCTGAATGTTACTTCGACCCTGAGCTG
Long Flanking Sequence:
TCTGATTGTTTGACATTAGAAAAATAAACATGTATAGCTAAGAGAACCTGAAAAGTTTTTCAAAATATGGAATCCCTATATAGGGTTTCTGAAGGAAGCTGAAATGAATCTTCTGTCCATATAACTTGTATCTTGTATCACCTGCTATTAATTTATCATTGTTTTGATACATTTATTTTGTATGTGTATGTACATGCATTTATTTATTTATATACTTGTAATGGAAATTTTTATTCTTTTTTTTATTTATTTATTATTATTTTTTTTTTTACTTTTTTTTAATATTCTTAACTGCGACCCTCTTACCGTTAGTTTACTATGAGGGACTGATGCACTGAAACAAAGCCCTGCCCCCTGTTAAATATTTAGTTTCAGTTGAAACTACATACAAAATACTGAAATAAAGTCTCAGTAACTTCCAGTTCACTTTAAACCTTCACTTTTCAGACTAATATTTTTTATAGGCACATTTTCTGACTGGTGTTTGTGTGTGTGTTTCA[G/A]CTTGTAACTGTAATGGAAAGAGCGCTGAATGTTACTTCGACCCTGAGCTGTATCGTGCCACTGGTCACGGAGGTCACTGCCGTAACTGTGCTGACAATACAGATGGGCCGAAGTGTGAGCGATGCCTGGCCAACTACTACAGAGAGGCCTCCGGTCAGCGCTGTCTGTCCTGCGGCTGCAACCCTGTTGGTGAGTAACAGCAATTCAGAAGGCTCAGGGTGGAAGATGCATCAATAGCCAAGCATATTATATTTTGCTTTGCTTTACTTTTTCCCCTTGGTTTTGTTGTTCATTTGTTTCTTTGTACATTCATGTAGTTTTGCTAGGTGTTTTTTTTTTTTTTGTCGTCTTTGTTTTTGTTTTCTCAACTTTTTTTTTCTTTTGTTTTTGGTTCTCAGTTGTTTCTTTGTACATGCGTGTTTGACGGTTTTGTTTTGTTTTTGTCTTCATTTGTTTTGTTTTCTTTTTTTCTCAACTTTTTTATCTTTTGTTTTTGTTAT
Associated Phenotype:
This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.
Control; 24 hpf
Control; 24 hpf
Mutant; 24 hpf
Mutant; 24 hpf
Stage Entity Quality Tag
Pharyngula:Prim-5
ZFS:0000029		 brain
ZFA:0000008		 quality
PATO:0000001		 abnormal
PATO:0000460
Pharyngula:Prim-5
ZFS:0000029		 extension
ZFA:0000106		 quality
PATO:0000001		 abnormal
PATO:0000460
Pharyngula:Prim-5
ZFS:0000029		 eye
ZFA:0000107		 quality
PATO:0000001		 abnormal
PATO:0000460
Pharyngula:Prim-5
ZFS:0000029		 notochord development
GO:0030903		 disrupted
PATO:0001507		 abnormal
PATO:0000460
Pharyngula:Prim-5
ZFS:0000029		 somite
ZFA:0000155		 quality
PATO:0000001		 abnormal
PATO:0000460

Mutation Details

Allele Name:
sa19814
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004277 Essential Splice Site 427 1593 7 28
Genomic Location (Zv9):
Chromosome 2 (position 35676756)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 35973466
GRCz11 2 35955923
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGGACACTTCTGAAATTGCTGTGTCTAAAGATTCCTCTTTTTCTCTTCAC[A/T]GACCGTGCTCTTGTAATCCAGCCGGAAGCACACAGGAGTGTGATGTCCAG
Long Flanking Sequence:
GTAAAAAAGTTTCACAAAACAAATCCAATTTATAATATAATTTTTGTGATTTGTTTATTTGTTTGTTTGTTTGTAAAATACATTAGAGGTAAGATAATTACAGATAGATTGTCAGACACCTGAAACAATAGGGGTAAAGTTTTCCTTTGCTTTTAATTTGAAGTAAAGAACTTCATTTGGTACCATCATTTTCTATGAATTGGTTATAAATACAAAATATATTACCTGAAAATGGCTTTGTTTTGTAACCATTTGTCTGATTTGCATCTGCAGGGTCTCTCAGCACTCAGTGTGATAACACTGGCAGATGCAGCTGTAAGCCAGGAGTGATGGGAGACAAGTGTGACAGATGCCAACCTGGATACCACTCGCTCTCTGAGGCAGGATGCAGGTAAAGATGTCTTTAACAACCAACCTGGAACACTTTGAACTTTTAAAGCACCTCAGATGCGGACACTTCTGAAATTGCTGTGTCTAAAGATTCCTCTTTTTCTCTTCAC[A/T]GACCGTGCTCTTGTAATCCAGCCGGAAGCACACAGGAGTGTGATGTCCAGACCGGACGCTGCCAGTGCAAGGAAAATGTGGACGGATTCAACTGTGACCGGTCAGACTCATTACTAGAGCAAATATCCGTGCACATGTTCACACACAGTAGCAACTGTTGGGGCTTTTTAAAGTCCCCTGTGCTGTTAGCGATGTCCACACTTGACATGTTCACAAGGACAAAAGCGTATAATTGCTTGATTTGTTTTAAAAATGTTCTCAAATTAGAAGCAAATGGTCAGCAGAATTAACCTGAACATCAACACTCCAGCAGCCCCATAAAGACCGTCCGGCTTTCAGCTCCTGCTCTGTTATGAGGACGTCTGCTGGAGCTTTAGAAACAGACATTTATAAGGGGCTTCTGACGTCTACACTGTTTTTCTTTCGGAAAGTCCCTGTGTGGGTGACACACGGAGGATCTGAGGCCCAGCCTGTGTGTGTGTTTTGTGTGTGTGTCTGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9866
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000004277 Nonsense 969 1593 17 28
Genomic Location (Zv9):
Chromosome 2 (position 35692130)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 35988840
GRCz11 2 35971297
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATTTGGTTTTCCTGCGTTGACGCTTGGAATGTTTGTACAGCATGTGACTG[T/A]GACCCAGAAGGCTCAGAATCAGCTCAGTGTAARGAGGACGGCCGCTGTCA
Long Flanking Sequence:
CAACTTCTTCGGATTCAGTTCATCGGGTTGCAAACGTACGGTGCCTTATCATTGGCTTACTGTAGTCTCAAATTTCACAACCAAACTTTAGGTCTTAAATTCACTGAAGTATTGTTTATAGGTCCCAGAGAATGTGTGTTATGTGTTATTTTGTTTTGTCTAGTCTTGATTGTGGTGTTTGTTTGTTTTTCCACATATAATTCACTTTATTAGGACTACAAATGTGATCATCATCGTGATGTAGGCCTTAAGTTCAATTCTCAAAGTCTTAGATTTGACTTTGTAATACAGAAATCCTTGTCTAGCAATTGTGCTAGATGCAAAATTAATCATTAAAAGTCATAAATTACAAAAATTATATTTTAGGTGTTAAACATTTATTTTGGATTTCACTGTATTAAGACTACAAATAAATCCAACAGTCATGATATAGGTCTTTGTGCTATATGCATTTGGTTTTCCTGCGTTGACGCTTGGAATGTTTGTACAGCATGTGACTG[T/A]GACCCAGAAGGCTCAGAATCAGCTCAGTGTAAGGAGGACGGCCGCTGTCATTGTCGGCCAGGTTTTGTGGGCTCTCGCTGTGATATGTGTGAGGAAAACTACTTCTACAACCGCTCGACACCTGGCTGCCAGCAGTGCCCTAACTGTTACAGCCTGGTCAGAGACAAGGTGAGCCATTTTCTCATGAAACTAGAATGATTCGTTTTAGAGCATGAAGCAACTTCTAATACACCTGTTGCATTCCTGTACAGGTAAACCAGCAGAGACAAAAACTGCTTGACCTGCAGAATTTGATTGATAGTCTGGACAACACTGAGACGACAGTGAGCGACAAGGCCTTTGAGGACAGACTGAAGGAGGCAGAGAAAACTATAATGGACTTGCTGGAAGAGGCTCAGGCTAGCAAAGGTATAGATTCTTGTTATAGATTACAACAGCTCACTGTGTGATGAAGCCATTGAATGTAGTTATATGTCCAAAAAATTCAAGATATTGAGAAA
Associated Phenotype:
Not determined