Busch Lab

ZMP

xrn1

Ensembl ID:
ENSDARG00000091652
ZFIN IDs:
ZDB-GENE-040426-1203, ZDB-GENE-040426-1203
Description:
5'-3' exoribonuclease 1 [Source:RefSeq peptide;Acc:NP_957327]
Human Orthologue:
XRN1
Human Description:
5'-3' exoribonuclease 1 [Source:HGNC Symbol;Acc:30654]
Mouse Orthologue:
Xrn1
Mouse Description:
5'-3' exoribonuclease 1 Gene [Source:MGI Symbol;Acc:MGI:891964]

Alleles

There are 11 alleles of this gene:

Allele Name Consequence Status Availability
sa31269 Nonsense Available for shipment Available now
sa19713 Nonsense Available for shipment Available now
sa19714 Nonsense Available for shipment Available now
sa32874 Essential Splice Site Available for shipment Available now
sa19715 Nonsense Available for shipment Available now
sa19716 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa31269
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000121772 None None 504 1 18
ENSDART00000125413 Nonsense 7 1697 1 42
Genomic Location (Zv9):
Chromosome 2 (position 16417717)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16928544
GRCz11 2 16597134
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTATTTTTATTTGAAGACTTACACGAGACGATGGGAGTGCCTAAGTTTTA[T/A]CGATGGATATCAGAGCGGTATCCGTGTCTGAGTGAAGTTGTCAAAGAGCA
Long Flanking Sequence:
AAACCTTGAAGGACTAGTTGACAAAATGTACCGCCGGTGAACTGCACTTCACCTTGGCCAAGAGTGTCGGAATGTTTTCGTGTCAAATGGCCTCTTCTCTCACATTACATCACACACAGCTCAGCCCTAGCGGTGGGGTTTGTTTCTACCGGAAGGCTGTTCTGGTCGTAATAGATTTTGGGCAACATTAAACGAGTTAACTTTAAAAAGTACTAGTACATTTTTTAGAAATACATTTGTTTATTGTTTCATGGCGTTCGGTTAATTTAATAGACGTGTTTTAGTGTTTTATGAGTGACGGAACGGCGTTACATGAGGTTACATCATGCGAGTTTCCACACGGAGGTTTTATTAGCTGGACCGTAACAGCTCATACAGAAACAAAACCGACTAGCAACACCAGTCTATGAAATTCTGATCACCTTGACTTCTGCATAGGTTACTTCATCACTATTTTTATTTGAAGACTTACACGAGACGATGGGAGTGCCTAAGTTTTA[T/A]CGATGGATATCAGAGCGGTATCCGTGTCTGAGTGAAGTTGTCAAAGAGCATCAGGTGAGCTAGTTTGGCTAAATATAACAGGCCGCATAGAGATCATTACAGATCTGAGAACAGAAAATCTGCCTTTACACTTTACCAAGCTACAAAACACTACAATTATTTTGCCTTCGCCCTTAACATGTTACGTGTAAAGTAAATTTTATCATTTTATAAAAACTATTTTTTTCTCCGATGTACAACAACATAATGACTGCTTCAAAGATTTTGAGAACTGTCTTATCTAGTCAGACAACATTTTATGATATGAAGCCTAGAGGTTATGGCATAGAGGTAAAGTTGGTTTTATATTCGGATATTCAGACATTCTTCTGAACTATATAATTTCAGAAAAGTATTCTTTGCAAGTTCTAAATAGGGAAACCATGATAGCAGCCAATGACTATCAAAGTACAACATTGTTCACAGTGAACTCGATAATGTTAATGTTGTTTAGAAGTCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19713
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000121772 None None 504 None 18
ENSDART00000125413 Nonsense 67 1697 2 42
Genomic Location (Zv9):
Chromosome 2 (position 16420327)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16931154
GRCz11 2 16599744
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGCACTTCCGTATTTCTGAAGAGAAGATATTCGCTGACATTTTTCACTA[T/A]CTGGAAGTGCTCTTTCGCATCATTAAGCCAAGGAAAGTGTTCTTCATGGC
Long Flanking Sequence:
GTATGGAAAATGTGCAAGTATTTTATTGCAGTAATAAACTAGGGCTTGACGATTTGGCCTAAAATCTAAATCTTGATTAATCGGAACGTTTTAGCTCGATTACAGTTAATAAACGATTATTTTACTTATGGTAAACAAATATGTGATAGTTATCATTTTTGTCCCAGAAAATTAAACAGAACTTAAATGTATATATAAATGACCATTATCATGTTTGTATTGTGTTGACTTCGCTTGCAATCAAATTGTTATCTTAAAGTTGCATCTATGTAATGCAGTTGAAGCTGTTTTTTCAATTATCACTTTATTGTTTGTGACATTATTAGGTTTTGTCAAGATGACACAAGCTTACATGTGTTCTCTCCACCTTCACAGATCCCAGAGTTCGACAACCTGTATTTAGACATGAACGGGATCATCCACCAGTGTTCGCACCCAAATGATGAGGATGTGCACTTCCGTATTTCTGAAGAGAAGATATTCGCTGACATTTTTCACTA[T/A]CTGGAAGTGCTCTTTCGCATCATTAAGCCAAGGAAAGTGTTCTTCATGGCCGTCGATGGAGTCGCACCCAGAGCCAAAATGAACCAGCAGCGTGGGAGAAGATTCAGGTATAGCAAAATCTAGAAGCTGTCGACATGCTTTAACATGTTATAAGCATGATCTCTAGTACATTAAGATGTTGCTAAAGTGTTATTTTTATCACATTGCTGTAAATTTATTTTAATTTTAAACATGTTGCTCATGTTTTAACACATTACTAGCATGGTATAGCATATTTTAGAATGATTATTGTATGTTTTAGCATGTTACTAGTAGGTTTTAACAAGTATTAGTTAACATAGTAATAACAACACATATTAGCACATTTTAGCATGTTTTAACACACTGCTATCGTATTTTAGAGTACTGCTATCATAACGTTATAGGTTTTGTCATGTTAACATTACTAGCGTTTTTTTGTTAATATGTCGATAACATGTTTCTGGAATGTTTAAAATATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19714
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000121772 Nonsense 38 504 4 18
ENSDART00000125413 Nonsense 127 1697 3 42
Genomic Location (Zv9):
Chromosome 2 (position 16421250)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16932077
GRCz11 2 16600667
KASP Assay ID:
2259-1799.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAAAATCAAGAAGGCCTTGGAGAAGGGAGAAGTTTTGCCCACAGAGGCC[C/T]GATTTGACTCTAACTGCATCACTCCGGGTTTGTGTTCATTTATCGCTTAC
Long Flanking Sequence:
TAGGTTTTGTCATGTTAACATTACTAGCGTTTTTTTGTTAATATGTCGATAACATGTTTCTGGAATGTTTAAAATATTGCTAGGACGAAAAAAAGTGTTAGCTTGTTTTAGCACCTAAATTAGCATGTTGTCAACATAACTCAAGCAAGGTTAGCACAATGTTTGCATGTTTCTAGTGTGAGGTAACATGTTGCTACCAGCATGAATTAATGTTAGCTAATATGTTTCTTGCCTGGTTAACATCGTTAGCATTACTAAAAGTTGTTAGCATGTCCTAGACTTGTTACTCACCTTTACTAACCATAGTAAACTTTAATATTTGAGTCTTTTGACGCCGTCAGTGAAAGTCTATGGGATTTTCATAAGCTCTTAAAGCCAACAGCTCATTTAGAAAGTCACAACTCACAACTTGTTTGTGTGTGTTTTAAAGGTCAGCAAAAGAGGCAGAGGAGAAAATCAAGAAGGCCTTGGAGAAGGGAGAAGTTTTGCCCACAGAGGCC[C/T]GATTTGACTCTAACTGCATCACTCCGGGTTTGTGTTCATTTATCGCTTACATATTGTCTTAGTGATGTCAAATGTATTATTCATCATTATCTGCAGGGTACATAAAAACTTCAGACTATTGATTTTGTTATGGGGATTCACAGTAGCACTGTAATAAAGGGAACTGTTCTCTCAATTAATTAATTGCTTATTAATGTGCTTGTTATTAACATATTATATAATGTGCTTATTATTGAAATATTATTTATAACATGGTTATAAAGTGCAAAGTTTGCATGATCATATTCTACATCCATTATCTTACTTAATATCTAAATTTCACTACTTAATAAGCAGCAAATTCTGAGTTGATTAAGGCAAAACTCATCATTATTGTTTTGTTAATAGTGAGTGAATTTACCTTTAAAATAAAGTCTAAACAAGTTTTCTTGAGGATCTTAACCTTTATTTTATGTGATTGTTGTAGGAACGGATTTCATGGCCAGGCTACAGGAACAGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32874
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000121772 None None 504 None 18
ENSDART00000125413 Essential Splice Site 1067 1697 27 42
Genomic Location (Zv9):
Chromosome 2 (position 16452040)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16962867
GRCz11 2 16631457
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGATGCTGGTATTGTGGAGAAGATTGAGGAGGAGCTGGAGAAAACGAAGG[T/G]GAGGATCACATACAAAAATTGACAATCACAGTTACTGTTGCTGGCATTAC
Long Flanking Sequence:
GAACTAATAGCTGAATACCTAGAACGGTGTGTTTGTGTATTTGTGGTCATAGTTAAAACTTCCACATTACCACCAGCACCTAAGTTTTTTTATGTCTTTATTTTTGTCATAGATTTTCAGAGGTGTTTGACCATGTAGCACGAAACAGCCACGATGACATATTTTACGAAGACGACATCTGGCCGGGAGAGGATGAGAATGGGTGTGTATGCAAACCAGCAGTCGTGCATGGAATTCATATGCAATGTCCTACTTTATTTCCATTACAAATTTTTACAGAAAGCTGCACTTAATAGTATGCCAGAGTTAATGATTATAATTTGACTGTTTCTTATTGTGATGCTTAAAAATAAATTAATAAAGAGTGGAAAAGGTCCAAGAGATCCAGGGCTGGTTGAAAACGCATCCAGTGAGCTCCATCTCCAGAGCATCATGTGATCTGCAGATCCTGGATGCTGGTATTGTGGAGAAGATTGAGGAGGAGCTGGAGAAAACGAAGG[T/G]GAGGATCACATACAAAAATTGACAATCACAGTTACTGTTGCTGGCATTACGTTAACAATGTGTTGATTTCTGGATTACAGGCAAAGAAGATGAACAAGAAAGTGCGGGTCACCGTGAAGCCCCATCTGCTTTTTAGGGTTTGTGTCTGTGTGTCAGTGTGTATGCTTAAGGAATGTGATATCTATGTATTGACATGCAAAGCCCTAATTGCACATGTAAATTACAGAGACGTCTAATTGATGTGTATGTTTTCATCTGGTATACATAGGGTTTATAATCTGCAATGTGTCTCTGAGACATTTCCTGTCAGAAGATGTTAAATAGATGTTTAGAATGTGTTTAACATGGTTAGGTCAGATTGTTGGTTTTCACACAATGCACTTTTTAAAATGCATTTTGCAAACGCATGCGTGCTCTCTTGAGTATAGCAGCCTAAACTATAGCTGTCTAAACTAGCTATACATCAAATAAGTTAGTATGTCTGTGTAGCTGCTTAACAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19715
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000121772 None None 504 None 18
ENSDART00000125413 Nonsense 1488 1697 39 42
Genomic Location (Zv9):
Chromosome 2 (position 16463553)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16974380
GRCz11 2 16642970
KASP Assay ID:
2259-1800.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCATATCATTTGCTCTTTTCTCTATGTTCTGCAGAGTCTGATCTTGTG[T/A]CAGGTGAAGTTGTCGAATGGTCTGATGGTTCACGGCCCTCAGTGTCAGTC
Long Flanking Sequence:
AGTCAATGTGTGTTTTTGATTTCATTTGTTAAAAGTTGATGTTCATTAAATAATCATAGATAGTGGATCGAGTGTGTTTCCTTCAATTAATTTATAATCAAGTAATGCACACTTCATATAAAAATCTCTCGCATGTAATATGTGAGCGTATTTACTGTACAAAACCTCTCAGTGAACTATGCGGGCAAATATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAATATTCATTTATTAATGGTAATCGAGTTAAAATGTTCAAATCCAAACCAGCCAAATCGCCCAGCCCTACCACAGTGTGCACGAAATTTCTTCATCATATGTAACAGAGTTCAGTTTTGAATTTGGTTAGGTGTTTTTAAATTAACTTTTCTCAGAAACTGGACGAATGATAACAATATACATATAATGGCCTTGTTTTGCTCCATCTTTTCATATCATTTGCTCTTTTCTCTATGTTCTGCAGAGTCTGATCTTGTG[T/A]CAGGTGAAGTTGTCGAATGGTCTGATGGTTCACGGCCCTCAGTGTCAGTCAGAAACCGAAGCTAAAGAGAAAGCTGCTCTCTTCACCCTTCAACGATTGGTAACTCGCTGATCATAATGTTGTAATATTCCTAATGAGCAAGCTCATGAAGAGTTAAAGTCAAAATTATTATTGTTAGAATTATTATTAATTTTTTTCTTTTCTTTTTTGAATATTTCTCAAATTATGTTTAACAGAAAGGAGAGTTTGTAGCAGAACAGAAAAGGAGTTTGTAATATTATTTAAAACCATTTTAAGGTCAATATTATTAGCCCCTTTAAGCAATATTTTTTTGATCGTCTATAGAAGAAACCATCGTTATACAATAACTTGCCTAATTTCCTGCCTAGTTAACCTAATTAACCTAGTTAAGCCTTTAAATGTCACTTTAAGCTGAATACTAGTGTATTGAAAAATAACTTGTAAAATATTATTACTGTCATCATGGTGAAGATAAAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19716
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000121772 None None 504 None 18
ENSDART00000125413 Essential Splice Site 1607 1697 41 42
Genomic Location (Zv9):
Chromosome 2 (position 16464644)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16975471
GRCz11 2 16644061
KASP Assay ID:
2259-1801.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGTGCCATCAGCAGCCGGCGGATCCCATAACCAGTTTGTTCCCCTTCAG[G/A]TAATGATTTGCGTCTAGACATGCACACGGAAATCAGTGGCTGTGTTTACA
Long Flanking Sequence:
ATATACAAGGGGGCTCATAATTCTGCCTGTATGTTAGTAGCAGCACTATATGTCATGATTAAATACAGTCAAGTCTGCAGTAAGTTTTAGTGCATAACTCTTTGTCCACTGCTGAATGAAGTCTGGTTTTCTGCAGAACTCGCTGGGCTCTTTCCCATTGCCTCCTCCCATATTCCCTGGAGTCCAGCAGATGAGACCGCTTGCACCTCATCCCTCCATGTTCGGACAGCCAGGAGGTCTGAGTCACTGCGTTGTCAATTTTCTCTTATTCTCTACAGTTGTTGTTTTAATGCAGATGTCCTCATGTTTACACTTGATATGACGCATTATTTATTTACACAGGTGGGTTTCTGATGCCCCCTCAAGGGTACGGGCCTCTTCCCTGGGGGATGCAGTTTCCCCATCAGGGGCAGCCGTTCTTTGGAGGAACTTTTCCTGGAGCACGAGGCCCTGTGCCATCAGCAGCCGGCGGATCCCATAACCAGTTTGTTCCCCTTCAG[G/A]TAATGATTTGCGTCTAGACATGCACACGGAAATCAGTGGCTGTGTTTACACTTAGCATAGATAACATTTTGTTAGAATGTGAAATCTGAAAGGTCCCGTGAAGTGCTTTGAAATGTGCATTTTTACTCTGTTTCATGTAATCGAACTGAATCACGAAGAGAGGGTGGGACGTAGAGTAGCTTCTCCCCTCTTAAAAGCTAGCCAATAGCTTTTTATTTTATTACAGCACTGCCAGTGAGAGGGGTTTAGATTAAGTGCATCAAAGTTCACCTTCAGTGCACCTTAAGTTCACGTGTTTCAAAACAAGGTATTTTAAAGAAGGTTGGAAAATTGTTACCATTGACTTCAAAAGCATTTCTCCTCTACTATGGATGTCAATGGCTGCCGCTTTCAAGCACTCTTCAGAATATGGTCTTTTGTTTTTTAACATTAAAAATTGAACAATATCAAGTTAGAAACAACTTGAGGTTGAGTAAATACTGAAAAACTTTTTTTTTTGG
Associated Phenotype:
Not determined