Busch Lab

ZMP

si:dkey-74f15.3

Ensembl ID:
ENSDARG00000012914
ZFIN ID:
ZDB-GENE-070912-575
Description:
Novel protein similar to vertebrate Rho guanine nucleotide exchange factor (GEF) 4 (ARHGEF4) [Source
Human Orthologue:
ARHGEF4
Human Description:
Rho guanine nucleotide exchange factor (GEF) 4 [Source:HGNC Symbol;Acc:684]
Mouse Orthologue:
Arhgef4
Mouse Description:
Rho guanine nucleotide exchange factor (GEF) 4 Gene [Source:MGI Symbol;Acc:MGI:2442507]

Alleles

There are 13 alleles of this gene:

Allele Name Consequence Status Availability
sa32868 Nonsense Available for shipment Available now
sa13647 Nonsense Available for shipment Available now
sa19710 Nonsense Available for shipment Available now
sa17428 Nonsense Available for shipment Available now
sa12665 Nonsense Available for shipment Available now
sa19709 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa32868
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057216 Nonsense 1139 3063 3 16
ENSDART00000133708 None None 665 None 10
Genomic Location (Zv9):
Chromosome 2 (position 16091459)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16602286
GRCz11 2 16270876
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTCAACAGTACACAGCCAATCACAAACTTCAGTGGGACAAAGCCAATCC[C/T]AGGATTTGGTAGAACAAAGTCGATCACCAGCTGCAGCCGAAAACAGTCAA
Long Flanking Sequence:
AATCACATGATTTAATAGAACACTTCAAATCACTAGACAACACAGAGCACAAGCAATCAGACATGAGTTATATAAACTGCAGTCAATCACAGGCCTCAGTAGAAATCTTGCAATCACACGAGTCTGTTGAACACAGCCAATCAGAACAGTCAGTAAAACACAGCCAGTCACAAGACACTGACAATTTTAGCCAGACACAGGATTTAATTAAGCACAGCCAATCACAGACTTTCATAAAATGCAAACACAACCAATCACTGGATGGCGTACAATATGATCAGTCAAAGATCTTAATAGAACAAACCCAATCACAGGATTCCGTAAAGGACAATCCATCCCAAGATCTTGTCAAACATAGCCAATCACAGGACACAGTAGAACCGAGTCAATCACAGGTCTCAGTAGAACACATCCAATCACAGGATTCCCAAGACTGCAGCCATTCACAGAACTCAACAGTACACAGCCAATCACAAACTTCAGTGGGACAAAGCCAATCC[C/T]AGGATTTGGTAGAACAAAGTCGATCACCAGCTGCAGCCGAAAACAGTCAATCACAGACTTCAGTGGAACACAGCCAATCACTGGATTCAGTGGAACACATGAAATCTCAGACTTCGGTGGAACACAGGCAATCACAGGTTGAATTGATTAAGGCACATTCCATGAACACCCGGTGGATGGTGACTGAGTCAGACACAGTAGCGTTTTATGACAAGGTGCGATTAAAACAAGACTGCATGGATGTTTGCGCAGATTGTGAAGTCGTTGAATCCTTGGGAGTTTTATCAAAACATGCTGACAATTTGAACTTCGAAAATAACGAAAGACTAAATTTCAAAACACAGGACTTAAATGACACTTCACCTGTTGTTTCTGAATACGAGTGTTTCCCACATGTGCCTAATGCATCTTCTATTGGAGTGCCAGATTCACTGCATCAGTGCACGATTAGCAATTCACCCTCAGACCTGCAGGTTAAAACTCAGCAGAGTTGGCCAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13647
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057216 Nonsense 1240 3063 3 16
ENSDART00000133708 None None 665 None 10
Genomic Location (Zv9):
Chromosome 2 (position 16091155)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16601982
GRCz11 2 16270572
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTGTGAAGTCRTTGAATCCTTGGGAGTTTTATCAAAACATGCTGACAATT[T/A]GAACTTCGAAAATAACGAAAGACTAAATTTCAAAACACAGGACTTAAATG
Long Flanking Sequence:
CCAATCACAGGATTCCGTAAAGGACAATCCATCCCAAGATCTTGTCAAACATAGCCAATCACAGGACACAGTAGAACCGAGTCAATCACAGGTCTCAGTAGAACACATCCAATCACAGGATTCCCAAGACTGCAGCCATTCACAGAACTCAACAGTACACAGCCAATCACAAACTTCAGTGGGACAAAGCCAATCCCAGGATTTGGTAGAACAAAGTCGATCACCAGCTGCAGCCGAAAACAGTCAATCACAGACTTCAGTGGAACACAGCCAATCACTGGATTCAGTGGAACACATGAAATCTCAGACTTCGGTGGAACACAGGCAATCACAGGTTGAATTGATTAAGGCACATTCCATGAACACCCGGTGGATGGTGACTGAGTCAGACACAGTAGCGTTTTATGACAAGGTGCGATTAAAACAAGACTGCATGGATGTTTGCGCAGATTGTGAAGTCGTTGAATCCTTGGGAGTTTTATCAAAACATGCTGACAATT[T/A]GAACTTCGAAAATAACGAAAGACTAAATTTCAAAACACAGGACTTAAATGACACTTCACCTGTTGTTTCTGAATACGAGTGTTTCCCACATGTGCCTAATGCATCTTCTATTGGAGTGCCAGATTCACTGCATCAGTGCACGATTAGCAATTCACCCTCAGACCTGCAGGTTAAAACTCAGCAGAGTTGGCCAGTATTACAAATACACACCGAAAAAGACGATTACTCAGTTAGTAGGTATCACATGGATGGTTACTGTTTGCAGGACAGTGAGCAAACAGAGTTTTACAAAACCTACCAGTGCCCTAACAGTACCATTAATTTTAATACACAGGGTGAGTTCACTGAAGCTCGGAAGGTTGTATCAACTGAAGGTGTATTTACTAGAGGTTGTATCAACACCAAACTTTTTGATGGCAAAAGTGTTGACATTGTAGGAGGACCGCAGAAGGACAGCAACAAGCATCACGTTATGAAAGGGAAAGAATGTACAATAGTTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19710
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057216 Nonsense 1576 3063 3 16
ENSDART00000133708 None None 665 None 10
Genomic Location (Zv9):
Chromosome 2 (position 16090148)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16600975
GRCz11 2 16269565
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAATAATAACATTAAAGCCATTACTTTAGAAGAGTGTGCCTCGGGAGTA[C/T]AAATGTCATTGCCTAGTTCATTGCAGAAATACAGTAGGTTTACAAATAAT
Long Flanking Sequence:
TAGAGCAGTCAGTAATTTACTCTGACAGTTCAGGATGCATAGAATATAAAAGGCCCAAAACGTTGAGCATTGCTTGTCCTGACATGACGACTGCTGAATCTGAAGGGTGTCCTGTAGACAGTCCTGTTGAATCACTTTCTACACTGTTTGAGATTCCACATGACAGATCTACAGTCAGCCCCACAGACATTTGCTTTGAGTTTAGTGATGGCCCTCATATGAACTGTACACAAGTAGCACAGAGTGTTATAGAATATTCAGATGCCCCCAAACTATTTCACCAGTTTGACACCCTGTCTGACAAACAAAGAAGACCTAATGAGTCAGCTGAAGCAATTGCGTCGAATGTTGATATTTTGTCTGGTGCACGTTCCGATCCTTTCACAAATGCACAGACTCCTTTTGATTATTCCCAGGTGAACAGCAGGAACTATACACAGAGCTCAGACACAAATAATAACATTAAAGCCATTACTTTAGAAGAGTGTGCCTCGGGAGTA[C/T]AAATGTCATTGCCTAGTTCATTGCAGAAATACAGTAGGTTTACAAATAATGCTGAATGCTTAGTCTCAAAAAGGGGTGATTACAAAAACATTGATTCTTTTAGTGCTCGTAATACTCTGGCTACCCCCTTCAAAGCACCTGAAATGAAGACTGAAGTGAACAGCAGAGAAAATGTTGTGAAATCTAGCAGTCACATAGATGTTACACAGAGGAAGCTCTGTGATTGCTGCGGTGGAAAGGAGTGCCAGCTGCAGACAGCGGGTGTATTTCAGTTCAAGGGCACAGACGCCATCAGTCAGCGCAGAACTGCAGTGTTGCAAACCTTGAGTCCCCTCCACACAGATGACAGCACACATGAAGCGGTAAAAGTAGACTCTACAAGCTGTGAATTTTCACATATGGTCAGTTTGCTTACACACAAACATCCGAATCTTGTCCAAGAAGACTTCGTATTACCACTGACTGGAGCTCATAAGGCTGATGATACTCATGTATTAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17428
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057216 Nonsense 2133 3063 3 16
ENSDART00000133708 None None 665 None 10
Genomic Location (Zv9):
Chromosome 2 (position 16088477)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16599304
GRCz11 2 16267894
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACGAAGCAGAACTTTGCAAAAGAACTCNNNCTGTTCCTGGGACGGTCTGTGAC[A/T]AGTGCATAMATCAGAGCCAAATTGATTGTGYYTTCTGTGCTTATCAGAAC
Long Flanking Sequence:
AACAAGATGAGATGAAGAACAACAGGTCACCCACATGCAGCAAATCTCACTCTTCACTGTACAAGACCCCTATATCTCAAAGTGCAGATCACCTTACTGATATTACAAAGCATTCTGACCACTCAAATGATGATGTTTTTGAAAGGGCTTTTGCTTTAAATGTGCAAAATAGAGAGAAACACATGCAACCTCAACACCCGTTTGAGCAGCAGCAGCAGAAAGATGGAGATGCACTCAGTTTTAGAGCTGGCCAGACAACAGAGGGGTTGCAACAAAAAAGATGCAAGAGCATTGATAACTTAAACTTACGCATGAAGCTGGCATTGGCTCACAAGTCTATTTCTAGCCTGTTTGAGACCAGATATCCTGAGAGGGACCAAGAGCAAATCTTACAGTTAGAGAATGAGGATGGGAAAACCAAGCAATCATGGAGAAAGACCAAACGATGTAACGAAGCAGAACTTTGCAAAAGAACTCCTGTTCCTGGGACGGTCTGTGAC[A/T]AGTGCATACATCAGAGCCAAATTGATTGTGCCTTCTGTGCTTATCAGAACCGGTCCATATTAACCAACTTACCAAATGTCCAAGCAAGATTGAAGAACACGTGCCATTCTGACCCGCAGAGTTTGAAATCTGCACCTCAGGAAGGGTTTGAAGATGGTAAATATCTGGAGGAAGGTGAGCAGCCTTGTGGTGCTTTCTCAGATTCAGACCAAGCATCGGTAGATGGTTTTGAGTCCAGTGTAGAGGACAGGTCGCTGTCACCTGCACACCCCACTGTTCTTGCACTTTCAAACCAAATGTCACCTACCTGGACAAGGTCCCTAAGCTGCTTCGAGACAACTGATACACCGACAAGGCCCATGAGCCCCAAACCACACAGTCCTGGTCTGGGCTGGACACAGCGGAGGAGCTTCCGCTACCCCTCAAGATCTGTTGCATCTTCTCTCTGCTTGCTTGGTCAGGGAGTGAGCACTGACGGTCTCTTAGACCCACCTCAGAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12665
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057216 Nonsense 2502 3063 6 16
ENSDART00000133708 None None 665 None 10
Genomic Location (Zv9):
Chromosome 2 (position 16077693)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16588520
GRCz11 2 16257110
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCTCTCCACAGAAACGAACCTCAGCGCMCCGGAAAAAGAGGCACATGGA[C/T]AGGTYGCACCTCTCGGTGAGTTTACTTTCTCAGCTAAATCTTGANNNNNAACACA
Long Flanking Sequence:
CAAAATATGTGAACAAAACTCATAAGGTATGCTTACACAACTACTTATTTAATCCTGTTAGAATAGCGTAAAATGGACTAAGCAGTGAACTCGTTGATCTCTAATATTGATTCTTTTCTGAAACTCTCATCTGAACTAAGACTTCTTGATCATTTGTGTTTTACTGTTCAGTTTATTTATGTAAAACATTCCTCCCACTATTGAAGCCATGACATGCTTTGTGTGTTTTGCAAGGCCTCTGAAAGCACTGCCTTATGAAATATGGATTCAAATGAGGAGAAAGACACAATGACCTCGTTTTGCTACTTGCTGACATCATGCCCCCTCTACAACCTTACTTTACACCACATGACAAGCCAAAGGGGCATTTCTTTTTCAGTTATGCTCATCTAGATCTTGAATCTTAACTTGTTTTTTTAGTACAGGAGAGAAACTAACTCTGATACATGCTGCTCTCCACAGAAACGAACCTCAGCGCACCGGAAAAAGAGGCACATGGA[C/T]AGGTCGCACCTCTCGGTGAGTTTACTTTCTCAGCTAAATCTTGAAACACAGTATGAGCTTGTACTTTTAAGAAATACAGTGCTGGTGTGTTGAAGATATACAGGAAGAGTGGAACAGTTGATCCTGGTGATTTGACTGATGGGTTTAACATATTTTCTTTACTCTTTTTATGAATATTGTTTATTATGGCTTAACTTGTGGATTCATTTTATGTATGATTTAAACCAGAGATAATATATAGTTCTCAGCATATATAAGTACACCCCTCACAATTCTACCTTTTAAATTTATATGTTTAATAGGAATCTATACAATATTACATTTGTGTATATACATTAGATTAGTCAGTACTGAAGCCAAATCTGGAGCTTACCTAACAAAATAACCTACGAGAACGGTCCAAAAACTAGTACAGCCAAATGTATATGTTATAGAAAAATATTAAATACTACCAAAAAAAGGAAAAATCAAAAGAAATAGAACAATTGAAAAATTTAGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19709
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057216 Nonsense 2984 3063 14 16
ENSDART00000133708 Nonsense 542 665 9 10
Genomic Location (Zv9):
Chromosome 2 (position 16027325)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 16538152
GRCz11 2 16206742
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGGCTGAGAGCCTTCACAGATGAGCGGGAGCAGGTCCAGCATGACCTC[G/T]AGACAGGTGAACGGCGCTTCTGGAGCTGTATAAAAACACTGCTTTTGCTG
Long Flanking Sequence:
GTGGTCTCACGGTCTCTTTCTCATTTCATTAGGGTGAAGACGTCTTGAGCAGGAGCTCTGATCTGATCTTTTCTGGAGACCTGACCAAGATCTCCCAGCCACAGGCTAAAGGCCAGCAGAGAATGTTCTTCCTCTTTGACCACCAACTGGTTTTCTGTAAGAAGGTCAGTCACTTGATGTGCCAGTGAGAGCAGTCACTGTTAGTCACGGCAGATGGTGTTCATGCAGGTATTAAAGTTTTACCGTCTTTTTAAAAACCACAGGATCTGCTTCGGAGGGATATCTTGTACTACAAGGGTCGGTTAGACATGGATGAGATGGAGGTGGTGGATGTGGAGGATGGGAAGGATAAGGACTTTAATGTGAGTGTGAAGAATGCCTTGAAATTGTGTTCTCCTGGAGGAGAGGAGGTTCATCTCCTGTGTGCCAAGAAGCCCGAACAAAAGCAGCGCTGGCTGAGAGCCTTCACAGATGAGCGGGAGCAGGTCCAGCATGACCTC[G/T]AGACAGGTGAACGGCGCTTCTGGAGCTGTATAAAAACACTGCTTTTGCTGTTCATAGCTAGTCTTTAAATTGATTATTTAATTATTATTATTTCCTTTATTTTACACTCTTAGTTCATATCCAAAAACATTTAAACATATATAAATATCTTATTATCATTTAAAAAAACATACAAACATTATTTCAATGCTTCCAATACCAGGAGTAGTAATTAGTACCGCTTAGTGTGGGATAATTTGAAACCTTTATAAATGTATTTCTTGGGATATTCAATCGACACATACAATTATACATAGTTGGACTATCCATGATTATGTTTGCAGTTTATGATAAAACTTTATACAGAATCTTTGTTGTTAAATGACAAAAATAGTTAAGAATTCCATTATATACAGTAAATTCTTAGTTCTCCAAAAATATGTTCTACCATTCCAGGTTATAAACAATCTCGCTTTCTCTCATTGACACACACACACACACACACACACACACACACACAC
Associated Phenotype:
Not determined