Busch Lab

ZMP

LOC570630

Ensembl ID:
ENSDARG00000061268
Human Orthologue:
EIF2C2
Human Description:
eukaryotic translation initiation factor 2C, 2 [Source:HGNC Symbol;Acc:3263]
Mouse Orthologue:
Eif2c2
Mouse Description:
eukaryotic translation initiation factor 2C, 2 Gene [Source:MGI Symbol;Acc:MGI:2446632]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa23583 Essential Splice Site Available for shipment Available now
sa23584 Essential Splice Site Available for shipment Available now
sa196 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa23583
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087187 Essential Splice Site 86 873 3 20
Genomic Location (Zv9):
Chromosome 19 (position 42456878)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 41899892
GRCz11 19 41484947
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTATGAAATAGACATCAAGCCTGAGAAATGCCCACGGAGAGTTAACCGG[T/A]AAAATCTTTTGACTCAACCTAAAATTTCCTACTAATTGTTTGGGTGCTCT
Long Flanking Sequence:
CATGTGATGCGATTTCCTAGGTCAGAATTCACCAAGCTTGAACTTTCCAATGCAGCAAACTGCAAACTTGTCGCATGAACTTTCGTTTCCGTTCTGACGCATTCACATGCGTATGAATGGAAATCTATGGGGAGAAAAGGGCAGTGTGACCGCAGCTTTAATAAAGGTACTAGAAACCTACTGAAAGGTGTGTTGAAGCAAGATGGAGCTAAACTCAGCAGGACACCGGCCCTCCAGGACTGAGTTTGGACACCCCTGATATAAATCATTGAATGCATTTGAAAAACCTGACTAATTTGTGCATGTGTCCTGCAGCTCCCGCGTCTCCTCCAGCACCACAAGAATATGTCTTCAAACCACCTCAGCGGCCAGACTTTGGCACAATGGGTAGGACAATCAAGCTTCAGGCCAACTTCTTTGAAATGGAAATTCCCAAGTTGGAGGTTTATCATTATGAAATAGACATCAAGCCTGAGAAATGCCCACGGAGAGTTAACCGG[T/A]AAAATCTTTTGACTCAACCTAAAATTTCCTACTAATTGTTTGGGTGCTCTGTACTTACTCGCTTGTTTTTTTTCTTTCTTTAGTGAAATAGTTGAGCACATGGTCCAGCACTTTAAAACGCAGATCTTTGGAGATCGAAAGCCTGTGTATGATGGGAGGAAGAATCTCTACACTGCCATGCCTTTACCCATTGGAAGAGACAAAGTATGCACCATTGAAGTCTATGTTAGCTTCATTACTCTAAATGCTACTTAAAATGCTGCACTGAAATCTTTACACCGTATAGATGATCATATATCACTGATGTGCCAAACTGCTCTGTTTAGGTGGAGCTGGAGGTCACGATTCCTGGGGAGGGAAAAGACAGGAGCTTTAAAGTCGCTATAAAGTGGATGTCCTGTGTCAGTCTGCAAGCTTTGCATGAAGCACTCTCTGGACGGCTACCAAACATCCCTTTCGAGACCATTCAGGCTCTGGATGTTGTCATGAGACATTTGCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23584
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087187 Essential Splice Site 438 873 12 20
Genomic Location (Zv9):
Chromosome 19 (position 42464350)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 41907364
GRCz11 19 41492419
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGCATTTGGTTGAATCCCTGTCTAATTTGGTCATGTCTTTGGCTGTTTC[A/G]GAACAAAGCAATAGCAACCCCAGTCCAGGGCGTGTGGGACATGAGGAACA
Long Flanking Sequence:
GGGCGGGGGGCTCTGTTGGAGCAAAAATTATTTGTCGCTGTTTGTCAAATAATTTTGAAATTAATGTTTTATTGACCAATACATTAATAAAATTTTTTGGAAAAAGTACTGAATAATATTTACAACTGAATAGTATTGTATTTTCAATGGAGTTTCTGTGCTAGCCTGCTTTCATCGGAAGTTCATCATTGGCTGAACAACACTAGCTGTGCATATAGCCCATTGCAACACTGAAAATGGACATTAGTAACAGGTGTGAACCAGAGCATTAAATTTCACCCTTACCTTCATTTGTTTGCAACAGATGAGAAGTGCCAACTTCAATACAGATCCTTATGTGCGTGAGTTTGGAGTCATGGTAAGAGACGATATGACTGAAGTCAATGGTCGGGTTCTTCAAGCACCGTCGATTCTCTATGGTGGAAGGGTAAGAATCTCCTCTGCTCAACTCAGCATTTGGTTGAATCCCTGTCTAATTTGGTCATGTCTTTGGCTGTTTC[A/G]GAACAAAGCAATAGCAACCCCAGTCCAGGGCGTGTGGGACATGAGGAACAAGCAGTTCCACACAGGGATTGAAATCAAAGTTTGGGCCATTGCCTGCTTTGCCCCACAGAGGCAGTGCACAGAACTCCTGCTGAAGTAAGTCAACTTTAAAGTACACATGAACCAGAAGCTGCGTTCGCTTTTTTTTTTTCATATTGTGATGCAGTCGCTATAGAAACAGAATATTAAATAAGAAATCAGTTGCCGTGACTTGTTTTTTCTGCTGCAAGCTGATTGGATGTAGCAAAGTAGGCATTTCATTCAGAAAGATCAGGAAAGGGCTTCGGGAGAGTTATTATAATCTAACAGTCATCACCTCATCAGTTCTGTTGGCTGTCAAAATTGACAGCTGAAGGAGAGTTGAGTATGTTGGCCACGCCCAATACCTTAGACAAACGTAATCTGAGAAGTTAACCAAAAAACCAGGAAGTGCATTTTCAGATTTCAATTATTAATTATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa196
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000087187 Nonsense 530 873 13 20
Genomic Location (Zv9):
Chromosome 19 (position 42465556)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 41908570
GRCz11 19 41493625
KASP Assay ID:
554-0108.1 (used for ordering genotyping assays)
KASP Sequence:
ACAGTGTGGAGCCCATGTTCAAACACCTCAAGTACACTTATCAAGGGTTA[C/T]AGTTGGTGGTGGTCATCTTACCCGGCAAGACTCCTGTTTATGGTAATTTA
Long Flanking Sequence:
ACCTTCCAGCTGCAATCCATCTCTGGGAAACATCCCCACACACCCATTCATACACTACGGACAATTTAGCTTACTCAATTCACCTGTACTGCATGTCTTTGGACTGTGGGGGAAACCAGAGCACCCGAAGGAAACCCATGCGAACCCAGGGAGAACATGCAAACTCCAGGCTCAAATCAGTGACCCAGCGACCTTCTTGCTGTGAGGCGACAGTGCTACCTACTGCGCCACTACTTTGCCTGTTTTTATTTGTACCTTAATCTGCCTGTTTTGTCATAGAGAAATATTAGCATTTAAGGAAATTATTTTACAAAAGTAAATACTGACCCAGATTTTTATACTATGTTTGTATCCTCAGGGCCTTCACTGACCAGCTTCGTAAGATCTCACGTGATGCTGGGATGCCCATTCAGGGCCAGCCGTGCTTTTGCAAATATGCCCAGGGAGCAGACAGTGTGGAGCCCATGTTCAAACACCTCAAGTACACTTATCAAGGGTTA[C/T]AGTTGGTGGTGGTCATCTTACCCGGCAAGACTCCTGTTTATGGTAATTTAATTATTATTATTATTATTTTTTTTTTCATCTCATATCTTTAGTGTATTTTTTACACACTCTAAATGCTAAAATTCTTACAGCTGAGGTGAAGCGTGTTGGAGACACTGTTCTCGGCATGGCCACGCAGTGTGTCCAGGTGAAGAATGTGCAGAAGACCACACCTCAAACCCTTTCTAACCTCTGCCTCAAGATTAACGTCAAACTGGGTGGAGTCAACAACATTCTTCTTCCACAGGGCAGGTGAGGGCAGCTGTTACAAATGCCTTTGACATGCAGAAAGCTTGAGGCAATTTCTTGTTGTCCTTTACGTCCTTTGATGCTTTCCCATGAAACTCAAAGGGTTAGTTCACTCGAAAATATGTAGTCTGTCACCCATTGATCATTCCAAACCTGTAAGACTTGGGTTATTCTTGGGAACAAAATTATCTCACTTTATTTTGTTAAGCAAT
Associated Phenotype:
Not determined