ZMP

si:ch73-190m4.1

Ensembl ID:

ENSDARG00000075785

ZFIN ID:

ZDB-GENE-090311-56

Description:

Novel protein similar to vertebrate hect domain and RLD 3 (HERC3) [Source:UniProtKB/TrEMBL;Acc:B8JLD

Human Orthologues:

HERC5, HERC6

Human Descriptions:

hect domain and RLD 5 [Source:HGNC Symbol;Acc:24368]
hect domain and RLD 6 [Source:HGNC Symbol;Acc:26072]

Mouse Orthologue:

Herc6

Mouse Description:

hect domain and RLD 6 Gene [Source:MGI Symbol;Acc:MGI:1914388]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa19588	Nonsense	Available for shipment	Available now
sa44513	Nonsense	Mutation detected in F1 DNA	Not yet available
sa482	Essential Splice Site	Confirmed mutation in F2 line	Not yet available

Mutation Details

Allele Name:

sa19588

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111114	Nonsense	332	992	8	24
ENSDART00000131544	Nonsense	332	350	8	8
ENSDART00000140883	None	None	408	None	10

Genomic Location (Zv9):

Chromosome 1 (position 51128099)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	49977190
GRCz11	1	50621016

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AACTGTAAACTAACTAAATGCTTCTCACACACAGAATATAATGACGAATA[T/A]ACAATTCAAAAACTTGTCGCGGGGGAGAATCATTCGTTTGCCTTGTATTT

Long Flanking Sequence:

ATTCTATGCAGAAAAAGCAAAAAATTTCCACAGATTCTGTTTGGCCCTAGCAAAAGGCAATTCAGAACAGCTGAGTTGTAAAGCTGAACTCTCAGTTCAGAGTTCAGCTTTATTTACTCAATAATTTCCCAAGTGAATTATTAATGACATTAAATAGTGAAGGTAAATTGAAATTCATACGCAACTCTGAAAAATGGCTCCAGCTGTGTTCAGTAATTTGACTTTTCATTTTTTCTGCATTAAGAAATCACACACTTGTATCGACTGCATCACCAAAGCTGATCTACTCATTTGGATGTGGGATGCAAGGGCAGCTGGGAAATGGAGAACAGGTCAAGCAGTCTGTGCCGTTACCAGTAGACCAGCCAACTGGTGACTTGGTTTTGTAGTAGCATAGTATTTTGTATATACATATATATTATATATATATTTATACATTAAGTAGATCAGAACTGTAAACTAACTAAATGCTTCTCACACACAGAATATAATGACGAATA[T/A]ACAATTCAAAAACTTGTCGCGGGGGAGAATCATTCGTTTGCCTTGTATTTCAAAGTAAGATGGATAGTTTTCATTCATAAATAGTTTGAAAGATAAATCACTGCTACACTGTGATGATTAATTATATGTTATGTTTTGTAGGAACTTGGAAATGAGGCTAATCCAGATCCAACCAGAGGGATTATGACATTTGATAACGGAATGATTGAACAATGCGAGTGTGGAAAAGATCCACGGAAAGCGATAAAGTGAATAAATGGCATCTTTATACTCTTTTCACTTGTTAGAAAATATCACAAACAATAATAAATAAATGGAAAATGACAATAATACAAGTTACAATTATAATTGTAATGCACTCTTTTAATAATTTCTGTTTCATTTTAAAAAATGTATATACACTCACCGGCCACTTTATTAGGTACACCTTACTAGTAGCTGGTTGGACCCCCTTTTGCCTTCAGAACTGCCTTAATCTTTCGTGGCATAGATTAAACAAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa44513

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111114	Nonsense	714	992	18	24
ENSDART00000131544	None	None	350	None	8
ENSDART00000140883	Nonsense	130	408	4	10

Genomic Location (Zv9):

Chromosome 1 (position 51135335)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	49984426
GRCz11	1	50628252

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTCAACGTGTTTAAGGAGCTTTGTGATCCAGCTTCTCAGCTCTTCATGTA[T/A]AACGACAACGAAACTATGATCTGGTTCCCCGCGAAGGTAAGGCAAAGACT

Long Flanking Sequence:

TCTCAGAGATAAATGGCTGTCGGTAAGCAACAAGAATGAGTTGCACACAGTACAGTGTTTGCATGTTTTGTTTTGATTTAATAACAAAGCAACAATTTAGTATGGAGGACAAATCCCTGCGGCTAGTTTCTTGATAGCTTGCTTCTTATCCAATTTTTAGTACTTCTAAAGCACATGTATTTATAATGCCTCATTCTGAATGCGTTTGTTAAAGCAATATAAATAAAATATAAATAAATAAAATGTAAATATAAACAAATAAATATAAATAAAATGTCAACCAACCTTAGTATAGGGAAGAATATTGCTTTGATAATCTGTCATGTTTGTGAAGGCTATTTATTAATTTCTTTTAATTTATAAGCTTTGGTATGAATTCATTTTTGGACACAGATTCTTTTCACTGAGAACGTGAGCAAAAGAACAGACGTCCACAAGAGGGACTTCTTTCTCAACGTGTTTAAGGAGCTTTGTGATCCAGCTTCTCAGCTCTTCATGTA[T/A]AACGACAACGAAACTATGATCTGGTTCCCCGCGAAGGTAAGGCAAAGACTTTTTTTATTATGTTAAAGGTTTATTTGTGATTGTTCCCATAACTCATTTTTACAGGATTATAGAATTATAGCACTATATGTACTTTTAATATTTAGATTAGTTCAGTGAAAATAAAATAAATAAAATATCTAATGATGCAAATTTAGATTTTTTTATTTAAATAACTTTTTGTTGTTGTTATTAATTTATAATCTACATTTTTATTATGATTTTATTATGATCACCAAAGATTTAGCAGTTGCAGATAGCTGGAGAACTACAAATCTTTAAATTTATCGAACTACAATTCCCATCATGCCTGGCACTCACACACCAGTTCTAGATCAGATTTTTGGAATTCACTTAGTGACCCCTACTCATTGTCCTGTGACCCCCACTTTGTGAACCACTGTTCTAGATTACCTCTTGATTTCACACTCACAGCTGCAGATCATCCTCATTGGTTACTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa482

Status:

Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111114	Essential Splice Site	726	992	18	24
ENSDART00000131544	None	None	350	None	8
ENSDART00000140883	Essential Splice Site	142	408	4	10

Genomic Location (Zv9):

Chromosome 1 (position 51135372)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	49984463
GRCz11	1	50628289

KASP Assay ID:

554-0333.1 (used for ordering genotyping assays)

KASP Sequence:

AGCTCTTCATGTATAACGACAACGAAACTATGATCTGGTTCCCCGCGAAG[G/T]TAAGGCAAAGACTTTTTTTATTATGTTAAAGGTTTATTTGTGATTGTTCC

Long Flanking Sequence:

GAGTTGCACACAGTACAGTGTTTGCATGTTTTGTTTTGATTTAATAACAAAGCAACAATTTAGTATGGAGGACAAATCCCTGCGGCTAGTTTCTTGATAGCTTGCTTCTTATCCAATTTTTAGTACTTCTAAAGCACATGTATTTATAATGCCTCATTCTGAATGCGTTTGTTAAAGCAATATAAATAAAATATAAATAAATAAAATGTAAATATAAACAAATAAATATAAATAAAATGTCAACCAACCTTAGTATAGGGAAGAATATTGCTTTGATAATCTGTCATGTTTGTGAAGGCTATTTATTAATTTCTTTTAATTTATAAGCTTTGGTATGAATTCATTTTTGGACACAGATTCTTTTCACTGAGAACGTGAGCAAAAGAACAGACGTCCACAAGAGGGACTTCTTTCTCAACGTGTTTAAGGAGCTTTGTGATCCAGCTTCTCAGCTCTTCATGTATAACGACAACGAAACTATGATCTGGTTCCCCGCGAAG[G/T]TAAGGCAAAGACTTTTTTTATTATGTTAAAGGTTTATTTGTGATTGTTCCCATAACTCATTTTTACAGGATTATAGAATTATAGCACTATATGTACTTTTAATATTTAGATTAGTTCAGTGAAAATAAAATAAATAAAATATCTAATGATGCAAATTTAGATTTTTTTATTTAAATAACTTTTTGTTGTTGTTATTAATTTATAATCTACATTTTTATTATGATTTTATTATGATCACCAAAGATTTAGCAGTTGCAGATAGCTGGAGAACTACAAATCTTTAAATTTATCGAACTACAATTCCCATCATGCCTGGCACTCACACACCAGTTCTAGATCAGATTTTTGGAATTCACTTAGTGACCCCTACTCATTGTCCTGTGACCCCCACTTTGTGAACCACTGTTCTAGATTACCTCTTGATTTCACACTCACAGCTGCAGATCATCCTCATTGGTTACTTGGACTATTTAAGCACCACAGCGACATTCATTTCTTGC

Associated Phenotype:

Not determined