ZMP
im:7150991
Ensembl ID:
ZFIN ID:
Human Orthologue:
WFS1
Human Description:
Wolfram syndrome 1 (wolframin) [Source:HGNC Symbol;Acc:12762]
Mouse Orthologue:
Wfs1
Mouse Description:
Wolfram syndrome 1 homolog (human) Gene [Source:MGI Symbol;Acc:MGI:1328355]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa17104 | Essential Splice Site | Available for shipment | Available now |
| sa18290 | Essential Splice Site | Available for shipment | Available now |
| sa1914 | Nonsense | Available for shipment | Available now |
| sa16422 | Nonsense | Available for shipment | Available now |
| sa31975 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa17104
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000112427 | Essential Splice Site | 235 | 895 | 5 | 7 |
| ENSDART00000112427 | Essential Splice Site | 235 | 895 | 5 | 7 |
Genomic Location (Zv9):
Chromosome 14 (position 15174744)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 14 | 17036730 |
| GRCz11 | 14 | 17342383 |
KASP Assay ID:
2260-7376.1 (used for ordering genotyping assays)
KASP Sequence:
CCAATACAGAAACAAAGAAAGATTTTGGAGAGTTTGGTGTCAAGAGATGG[T/A]AAATGCATCATTATCTTTCNCNTTTAGAGTCTGTTTAGTTCTATACYGGTAT
Long Flanking Sequence:
ATAGACATGCATGCATAAAGTGTAGTGCAAATATAAATACCCATTTTTTACCCATAGGCCGTTAAACAAAGAGAAACGGTTGGACGTGATGACTTTAGTAAGATGCAAATTGACGTATGATGTAATCTAGCAACATTTAGTGACTTTTCGGGCAGAGTTTGGCACCTTTTCATTGAAAATAGTTGGCAACACTGGTCTAACAGTCCAAAAATGGGCTAGCCTTCAGAAAGACAGAAATTTGCATGCATAGGGGTGTTCATGAGGGTTTTAGGGCGAATGAAACAACAGAAACTGCTACAATTGACTTAAATATGTCTTTATTTGTTTTCCTAATTTAAACAAACAGGGTATGTATTTGAAATGACATAAAGGTTATTAAAGGAGGTTTACTAAAACTGACATGTGATGTGTCCCCCTGTAGATGGCGCTTCCCGCAGCCCTCTCTCCAGCCCAATACAGAAACAAAGAAAGATTTTGGAGAGTTTGGTGTCAAGAGATGG[T/A]AAATGCATCATTATCTTTCCTTTAGAGTCTGTTTAGTTCTATACTGGTATTATTTATGTGATAAAAAAACAATATATTAACCTGAATTTGTGTATTTGTGCTTTGGCAGAGACTGATTGCATTGGTGTAGAAGAGTTTGTTGAGAATACCAAACAATACGCTGAGGGTATTTCACCATCCATGGAAGGGGTAGCAGGGGATGATGATGACGATGATGAAGAGCCAGTAAAACATCCAGATGAGCTGCCTTTGCACCAGAAGGTGATCTTATGTTTTTGTTTGGATGTTAAAACTTGCAGAGCTGATTCATTGTGGACTGCCTATGTGGTGAGCTGTCCACACAAATGGTAACCAAAGTGAAACTGATTATAATTGTGAAATACTCTTTATAATCCTTAAGATTGAATGGGAACAAACTGTGTAAAACACATTTTTTACTCAAGATTCTAAATTAATTGTTATATAAAAACCTTAGGCTATATAAAGTTTTTCAAGTCAAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa18290
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000112427 | Essential Splice Site | 235 | 895 | 5 | 7 |
| ENSDART00000112427 | Essential Splice Site | 235 | 895 | 5 | 7 |
Genomic Location (Zv9):
Chromosome 14 (position 15174744)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 14 | 17036730 |
| GRCz11 | 14 | 17342383 |
KASP Assay ID:
2260-7376.1 (used for ordering genotyping assays)
KASP Sequence:
CCAATACAGAAACAAAGAAAGATTTTGGAGAGTTTGGTGTCAAGAGATGG[T/C]AAATGCATCATTATCTTTCNCNTTTAGAGTCTGTTTAGTTCTATACYGGTAT
Long Flanking Sequence:
ATAGACATGCATGCATAAAGTGTAGTGCAAATATAAATACCCATTTTTTACCCATAGGCCGTTAAACAAAGAGAAACGGTTGGACGTGATGACTTTAGTAAGATGCAAATTGACGTATGATGTAATCTAGCAACATTTAGTGACTTTTCGGGCAGAGTTTGGCACCTTTTCATTGAAAATAGTTGGCAACACTGGTCTAACAGTCCAAAAATGGGCTAGCCTTCAGAAAGACAGAAATTTGCATGCATAGGGGTGTTCATGAGGGTTTTAGGGCGAATGAAACAACAGAAACTGCTACAATTGACTTAAATATGTCTTTATTTGTTTTCCTAATTTAAACAAACAGGGTATGTATTTGAAATGACATAAAGGTTATTAAAGGAGGTTTACTAAAACTGACATGTGATGTGTCCCCCTGTAGATGGCGCTTCCCGCAGCCCTCTCTCCAGCCCAATACAGAAACAAAGAAAGATTTTGGAGAGTTTGGTGTCAAGAGATGG[T/C]AAATGCATCATTATCTTTCCTTTAGAGTCTGTTTAGTTCTATACTGGTATTATTTATGTGATAAAAAAACAATATATTAACCTGAATTTGTGTATTTGTGCTTTGGCAGAGACTGATTGCATTGGTGTAGAAGAGTTTGTTGAGAATACCAAACAATACGCTGAGGGTATTTCACCATCCATGGAAGGGGTAGCAGGGGATGATGATGACGATGATGAAGAGCCAGTAAAACATCCAGATGAGCTGCCTTTGCACCAGAAGGTGATCTTATGTTTTTGTTTGGATGTTAAAACTTGCAGAGCTGATTCATTGTGGACTGCCTATGTGGTGAGCTGTCCACACAAATGGTAACCAAAGTGAAACTGATTATAATTGTGAAATACTCTTTATAATCCTTAAGATTGAATGGGAACAAACTGTGTAAAACACATTTTTTACTCAAGATTCTAAATTAATTGTTATATAAAAACCTTAGGCTATATAAAGTTTTTCAAGTCAAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa1914
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000112427 | Nonsense | 253 | 895 | 6 | 7 |
Genomic Location (Zv9):
Chromosome 14 (position 15174907)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 14 | 17036893 |
| GRCz11 | 14 | 17342546 |
KASP Assay ID:
554-1904.1 (used for ordering genotyping assays)
KASP Sequence:
CTGATTGCATTGGTGTAGAAGAGTTTGTTGAGAATACCAAACAATACGCT[G/T]AGGGTATTTCACCATCCATGGAAGGGGTAGCAGGGGATGATGATGACGAT
Long Flanking Sequence:
ACCTTTTCATTGAAAATAGTTGGCAACACTGGTCTAACAGTCCAAAAATGGGCTAGCCTTCAGAAAGACAGAAATTTGCATGCATAGGGGTGTTCATGAGGGTTTTAGGGCGAATGAAACAACAGAAACTGCTACAATTGACTTAAATATGTCTTTATTTGTTTTCCTAATTTAAACAAACAGGGTATGTATTTGAAATGACATAAAGGTTATTAAAGGAGGTTTACTAAAACTGACATGTGATGTGTCCCCCTGTAGATGGCGCTTCCCGCAGCCCTCTCTCCAGCCCAATACAGAAACAAAGAAAGATTTTGGAGAGTTTGGTGTCAAGAGATGGTAAATGCATCATTATCTTTCCTTTAGAGTCTGTTTAGTTCTATACTGGTATTATTTATGTGATAAAAAAACAATATATTAACCTGAATTTGTGTATTTGTGCTTTGGCAGAGACTGATTGCATTGGTGTAGAAGAGTTTGTTGAGAATACCAAACAATACGCT[G/T]AGGGTATTTCACCATCCATGGAAGGGGTAGCAGGGGATGATGATGACGATGATGAAGAGCCAGTAAAACATCCAGATGAGCTGCCTTTGCACCAGAAGGTGATCTTATGTTTTTGTTTGGATGTTAAAACTTGCAGAGCTGATTCATTGTGGACTGCCTATGTGGTGAGCTGTCCACACAAATGGTAACCAAAGTGAAACTGATTATAATTGTGAAATACTCTTTATAATCCTTAAGATTGAATGGGAACAAACTGTGTAAAACACATTTTTTACTCAAGATTCTAAATTAATTGTTATATAAAAACCTTAGGCTATATAAAGTTTTTCAAGTCAATTTGAGCTTGTGGTAAATGTTGTGTGCAATACAAATACATCAAAGTAACACAATCAGTGTTATATCATTTCTCTACAGGCAAAAGTTACCTTGTTTAATACAAATACAGGGATTGTATTTTAAAGTTCAAATCTAAACCCCAAAAAATGTAAACTGATTCAAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16422
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000112427 | Nonsense | 493 | 895 | 7 | 7 |
Genomic Location (Zv9):
Chromosome 14 (position 15179912)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 14 | 17041898 |
| GRCz11 | 14 | 17347551 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGGGTCGTATAATTGGCGGYGCTTGGTTCAGCATGCGCCTTGGTGACTG[G/A]TTGGTAATGCATGTAGGTGTGCCTTGTGTTCTCTATCTCTACCTMYTGTT
Long Flanking Sequence:
TTCTTCTTCATCATTTCCAACCTCACCCTGGAGTTCTTTGTCCTCGTCATCCCCCTAATTATATTCTACCTCTCCTTTGTGTCAATGGTCATCTGCACCCTACGAGTCTTCCAGAACAGCAAGGCATGGGAGAACTTCAGAGCGTTGACCGTCATGTTGTCTCATTTTGAGCCGGGGATTGACCTGGAGCAGGCCGAGTCTAACTTCACATGGAATCACCTTGAGCCATACCTCTACTTTCTCCTTTCTACGCTTTTCCTTATCTTTTCGTTTCCTGTGGCTGACAAGTCCTGGTTGCCATGTTCAGAACTGGCTATGGTTGCAGTCTTCTTCACTGTAAGCAGCTACTTGAGCCTGCGACCATCGGCACAACAGCATGCCAAATTTGCTCTGCTTTCCCAGGTTGCCTCCGCCATTTTTACATTCATTAATCGGTTGCTGGGAGGCTGGGTGGGTCGTATAATTGGCGGCGCTTGGTTCAGCATGCGCCTTGGTGACTG[G/A]TTGGTAATGCATGTAGGTGTGCCTTGTGTTCTCTATCTCTACCTACTGTTCTTGTGTACCCGTATGGCCACAGCAGGTGGTGCACGTGGCACCTACTGTGTGCTTCTTCCCAACCTAGTGTGCTTCATCTGGTGTGAAGTGTGTGTTACGCTGCTGCAAGAGTCCACTGTATTGGGGCTAATGCGCTCAGTTGTGGGCTACCTACTTTTTTTCTTTGCTCTGCCCGTGCTGTCGCTGGCTCTAGCAGCTGTAATGCTGGTTCAGCTGGTGCAGTGGTTCCTCGCCCTGGAACTGACCAAAATGATCGTAACAGTGTGCATCTGCGTGCTGCCTGTCCTGCTTCGCTGGTGGACTCGTTTTAGCGTGTCGCCTTTGGCAGTGCTTCGCTCTTTGCGTCGTAGCAGTGTGGTGAAGTTGATCCTTGTGTGGATTTCAGCGCTGGTGCTCTTCAGCTGGTTCTACGTGTACCGTTCGGAAGGGATGAAAGTATACAACTCCAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa31975
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000112427 | Nonsense | 851 | 895 | 7 | 7 |
Genomic Location (Zv9):
Chromosome 14 (position 15180984)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 14 | 17042970 |
| GRCz11 | 14 | 17348623 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCTTAAAGCCTTGAACTGCAAGACTTGTGCCTCACCTCTTATACCAATA[C/T]GACGACAGGTCAAGATCGAGCAGGATTGGAGGGTTAATGCCAGAAATGCC
Long Flanking Sequence:
AGATCATCTGCAGCCACTTAGAGGGACACCGAGTGACGTGGGAGGGACGGTTCAAGTATGTTCGTGTCACTGAGATTGAGAATGGGGCACAAGCTGTCGTCAATCTTCTACCAGTCTTGATAGCAGACTGGGTCCGATGTCTGTATGGAGAGGAGTACCCTGCTTGTGATGAGAATCAGACGGGACCTGCTGAACCTCTGTGTCAGCTCAAGACACTTGCAAAGCACAAGTGTCATGTCAAACGTTTTGACCACTACAAGTTTGAAGTGACCATGGGGATGCCCCAGAAGGGGCGCAATGGGGCACAAGATTTTGATGATGGCACAAAAGACATTGTATTGCGGGCAAGCAATGAATTCCGGAGAGTCCTGCTGGTGCTCAGCTCAGGCAGTGTGGTGGAGTTCAGTACAGTTCTCGAGGGCAGACTGGGCAGCAAATGGCCAGTGTTTGAGCTTAAAGCCTTGAACTGCAAGACTTGTGCCTCACCTCTTATACCAATA[C/T]GACGACAGGTCAAGATCGAGCAGGATTGGAGGGTTAATGCCAGAAATGCCTTAGCATTTGCCTTCAATTTTGTTTTCCATCCTCTACTTTCAGCTGAGATGGATGCTACTGCAGCTACTACAGAAGTATCTGTGTAAAAGGACATTTGGCATACACTGCAGTATTAGACTAAATTTTTATGTGCAAGAGACTGTTGATATTTGATAAAGTGCTTTTGATGAAGGCATGATCAAAACGCCAAAGGCGTTGTCATCTTGTTTTGTCCATTTCCTATTTGAAAATGAACAAAGATGTAATCAGAGCCTTAATATATCCTAGGGATACACTACTCTACACATTTGGTAATTCTTTTTTACACTCAGTTAATGGAGCTCTTTCCTAATGTGCTGTTGATCTAAATCAATTTAGTTAAATAGGCTGCTATACATACTAACTGTGCAGAGTGGTGGCTCCTTAGGACTGAAATTTAAAACCTTTGCTGTAGCAAGCAGTGTCCAATA
Associated Phenotype:
Not determined