ZMP
cnot6
Ensembl ID:
ZFIN ID:
Description:
CCR4-NOT transcription complex, subunit 6 [Source:RefSeq peptide;Acc:NP_997825]
Human Orthologue:
CNOT6
Human Description:
CCR4-NOT transcription complex, subunit 6 [Source:HGNC Symbol;Acc:14099]
Mouse Orthologue:
Cnot6
Mouse Description:
CCR4-NOT transcription complex, subunit 6 Gene [Source:MGI Symbol;Acc:MGI:2144529]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa1905 | Essential Splice Site | F2 line generated | Not yet available |
| sa43683 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa415 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa1905
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000030330 | Essential Splice Site | 194 | 566 | 6 | 12 |
| ENSDART00000031028 | Essential Splice Site | 185 | 557 | 6 | 12 |
Genomic Location (Zv9):
Chromosome 21 (position 31539379)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 32738849 |
| GRCz11 | 21 | 32772107 |
KASP Assay ID:
554-1895.1 (used for ordering genotyping assays)
KASP Sequence:
ACCTCGCTCATGGATACCACTGCAGGAGCCAGACAGAACACGGCCAGCAG[G/A]TGAGCAGGTTTCAYTTTAGCTCTGATTGTTACAGACTTTCGCTGCTGCAT
Long Flanking Sequence:
ATGCCATGTTCTGATTCCATAATTTTGCACGTTCCTGAGACATTTCATGCTTCATGTTTGGTGATTCTGTAGGAAACCCTCTTGCACAAGAAATCTTGAACCTCTATCAAGAGCCTGATGGGACCCGTCGGCTTCTCAACTACCTGCTGGACAATCTCGCAGGCACCAAACGCGGTGAGTCAACCATCATAAAGCTGCCCCGCTTGTGTGGTATTATCTGAAAAGCATCTATTCTTGTACACGCTCTTTTTACAGCAGATTAATTTCATGCAATCAAATGAGTCACAGCATTGTTGTCTGAACTCTCTTTTGATTAGTTCTGAATTACTGTGGGAATAATTACGATGTTCTTGCACTGCAGTGTGGCAGTCGGTCTGTTTTTGAGGTTTAATCACTGACATTTGTTTTTATTTCATTTTTATCCCCTGTAGCACCTATAGAACAACCTCCACCTCGCTCATGGATACCACTGCAGGAGCCAGACAGAACACGGCCAGCAG[G/A]TGAGCAGGTTTCATTTTAGCTCTGATTGTTACAGACTTTCGCTGCTGCATCTATTCTTTCACTTCACTTTTATACTGCTGTAACAGTTTCGAGAATTGTTTGCAAAAAATAAAGTGAATTAAAACGTAGTTTGGATTGAGGCAGTTTTACTTGATGAGGGATTGCACAGTTAATCAAATATTCCAAAATAGGAGGGAAATAAACGGAATAGAAATTTGTTAAATTAGCAGTATTAGTGTTTTATTCTTGGTGGTAGTGTTTTTCATGCTCTTCTTTTTTTATGTACTTCAAATAACTGAACTAATATCTAAATCCTTAGCCATAGTTATTGTTAACTGCTGCATCAAATTAACCACCTTCAACAACAGTCTAATATGCATGCAAGGTAAAAAAAAAAACACTTTCATTGACTTATAATATGCATTTATTTTTACCTAATTATCCTAGAGACTCCCATATGATTCGTTCAGCGGTTCATCAGTTCCCAAACCCCTCCTTAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa43683
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000030330 | Nonsense | 291 | 566 | 8 | 12 |
| ENSDART00000031028 | Nonsense | 282 | 557 | 8 | 12 |
Genomic Location (Zv9):
Chromosome 21 (position 31537039)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 32736509 |
| GRCz11 | 21 | 32769767 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCCGAGCCAGGACCATGTCTGAATCTGACCGCAAACATGTGGACGGCTG[T/A]GCAGTTTTCTACAAAACAGACAAGTGAGTCTATCATAAGAACATCGCTGA
Long Flanking Sequence:
CACAACTGAATTGAACTAAGGTTTTTGAATGGAATTGTAGGAGCCAGCTTTTATTAAATCTTTTTTTTTTTTTCTTCACACTTCAGCACTTTTCTCTGTGATGTGCTACAACGTGCTGTGTGATAAGTACGCCACGCGTCAACTCTATGGCTACTGTCCCTCATGGGCCCTCAACTGGGAATACAGGAAGAAGTCCATCATGCAGGAGATCCTCAGCTGCAGTGCAGACATCATCAGCCTACAGGTCTGTCAGCCTTTCTCATAAAGCCACAGCACTTCTGTTTCAAATAAACTCACAGCACAGTTTCATCCAGGTGGCCAATGAAATCAAATTGCTTCAAATGAATGGTGTCTTGTTGGGTGTAACAGGAAGTGGAGACGGAGCAGTACTACAACTACTTCCTGTTGGAGCTGAAGGAGCAGGGTTACGAAGGTTTCTTTAGCCCCAAGTCCCGAGCCAGGACCATGTCTGAATCTGACCGCAAACATGTGGACGGCTG[T/A]GCAGTTTTCTACAAAACAGACAAGTGAGTCTATCATAAGAACATCGCTGACTTTTAGTTTAGTGTTTCTCATTTCTATTTATCTTTTTCCTGCCATCCTTGGAGATTTGTGTAAACAGGGTTCTCACTATGCATGGGATGATAACCGGTTTCAAGGTTTACCACAGTTTTGAAAAGTCAAGATATTAAAAGCGCAAAAATATTTTGTATATATCTTCTATCTTCATTAAAGATGTATATATCTTTAGAAATGTCAGCTGTTTATTTTAATTGTTTTAATTATTATGACATTTTTACTGTTCCAAGATGTAAGGTGTGTTCTAATGTGTAATCTATTGTGTTAAATGGGGGGAAAAAGTAGTTTTTTTTTTTGTTTTTTTTTTAACTAAGTTTAAAAATAATTTTTACAGTAGTAAACAATACTGTGATATCGTGAAAGTGAAATTTTTATTTGAGGTTATCATACCATCAGAAACTTATACCGGCCCATGCCTAGTTCCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa415
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000030330 | Nonsense | 491 | 566 | 11 | 12 |
| ENSDART00000031028 | Nonsense | 482 | 557 | 11 | 12 |
Genomic Location (Zv9):
Chromosome 21 (position 31533607)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 32733077 |
| GRCz11 | 21 | 32766335 |
KASP Assay ID:
554-0275.1 (used for ordering genotyping assays)
KASP Sequence:
TTCAAACTGAAGAGTGCTTACGAGAACGGCCTGATGCCTTACACCAACTA[C/A]ACCTTTGACTTTAAGGTTTGACTTTTTTTTTTTTCATACAATACTTCTGT
Long Flanking Sequence:
GAAAGCCTCTGCATGGCATGGAGAAACAGCTCCTCCTGGTGGCCAACGCTCACATGCACTGGGACCCAGAGTACTCGGACGTGAAGCTCGTCCAAACCATGATGTTCCTGTCGGAAGTGAAGAACATTGTGGATAAAGCCACTCGCAGTCTGAAGCTCTCCTCAGTTTCTGGAGAAACCAATGCCATTCCTCTTGTCCTGTGCGCTGACCTCAACTCTCTGCCTGACTCAGGTGTGTATGCCTCCTAATGAATTGATTTATTTTTATATTTAATTCTTGCTTGATTCCTGAGGAGACTTTCTTGTGCTCGTAGGTGTTGTGGAGTACCTGAGCACAGGTGGAGTGGACGGCGCACACAAGGACTTTAAAGAGTTGCGCTATATTGACAGCTTGACCAACTTCAACTGCAATGGCAAGAATGGCACCTCCAGCACCAGGATCACACACGGCTTCAAACTGAAGAGTGCTTACGAGAACGGCCTGATGCCTTACACCAACTA[C/A]ACCTTTGACTTTAAGGTTTGACTTTTTTTTTTTTCATACAATACTTCTGTCATTCACTTCAGTAGCACTTTATATAAAGCGTTTATTTTGTTATCCAAGGGCGTAGATTCACTCTAACCATTGGTGGGGACATGCATCCCTAGAGTGCATGCATTAAACCTCACAAATTCTGTTATGCGCTTTTTAAAAACATGCTTAACCAGTTAAACTCTGCGTACCCGGTACCGGGAACAAAATGACGTCATCGGGAGAATAATTATAGATTTAAGAGGTCTTTCTGCATCAATAACACCATATGACCTGCTGGGTGAAAGTTAAAGCTGGAATTATACTCCCACCTGGCACCGCATCGCGCACCTCCACTGACTGCGCGCGCACCTCGCGAAACGACCGAGGCTTTTATACTCGCTTTTCTATACTTCTTTAAAACGACAGGGGGCGGTCAGAAGAAACCCACCGTAAAGTCAGATGGATAAACAGAGAGATGGAAAGTTTCCGGA
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |