ZMP
unc45a
Ensembl ID:
Description:
unc-45 homolog A [Source:RefSeq peptide;Acc:NP_001017671]
Human Orthologue:
UNC45A
Human Description:
unc-45 homolog A (C. elegans) [Source:HGNC Symbol;Acc:30594]
Mouse Orthologue:
Unc45a
Mouse Description:
unc-45 homolog A (C. elegans) Gene [Source:MGI Symbol;Acc:MGI:2142246]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa15522 | Essential Splice Site | Available for shipment | Available now |
| sa18626 | Nonsense | Available for shipment | Available now |
| sa44243 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa15522
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000039786 | Essential Splice Site | 126 | 218 | 3 | 6 |
| ENSDART00000103033 | Essential Splice Site | 126 | 935 | 3 | 20 |
| ENSDART00000130466 | Essential Splice Site | 126 | 935 | 3 | 19 |
Genomic Location (Zv9):
Chromosome 25 (position 8885556)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 25 | 8580621 |
| GRCz11 | 25 | 8657689 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAGCTTTCCAGGATCTKCTTAGACAGCTCGGAGCTCAGATCCAGCAGAAG[G/T]TGTGGGTTAWGAGTGATGCTCGCACTGTTAATATTAATGATSTGAAAATA
Long Flanking Sequence:
TTCCACGTATATTTTTTCTGACTGTGTAGATGTCCCAGGACTCCTCTGCACTGAGGGAGGAAGGAAACAACCATTTTAAAGCCGGCGATGTCCAACAAGCTCTGACCTGCTACACAAAAGCCCTGAAGATCAGCGACTGTCCATCCGAGAGTGCAGTCCTGTACCGCAACCGCTCAGCATGTTATCTTAAACTCGAGGACTACACCAAAGCAGAAGAAGATGCCACAAAATGTAAAAAAGAAGAACACATAAGTATGTGGATTTTCATCACAAACACATCTCCTAACTAAATCGTCTGTTTCTTTGTTTTTTTTTGCTCTCAAGCTTTGGATGTTGATCCAGGTGACATCAAGGCCCGGTTTCGTCGAGCGCAGGCTCTGCAGAAGCTCGGGCGGCTGGATCAGGCGTTCATGGACGTTCAGAAATGTGCACAGCTCGAACCCAAGAATAAAGCTTTCCAGGATCTGCTTAGACAGCTCGGAGCTCAGATCCAGCAGAAG[G/T]TGTGGGTTATGAGTGATGCTCGCACTGTTAATATTAATGATGTGAAAATAACCCCATATTTGTGTTTATATATGTGTATAGGCAACACAGCTCTCCTCCACAGACTCACGGGTTCAACAGATGTTCAAACTCCTCCTGGATAGTTCAGCACCAATTGCAGACAGACAGAAGGTGGGTAAGACTTAAACGGATAGTTCACCCAAAAATGAAATCTGCTTACTATTGACTCACACGCAGGAATTTCTTTCTTCTGTTGAACACAAAACAAGATATCCTGAATAATGTTGGGGGAAAATACAGTCATTGGCGTCCATTGTATGAACACAAAATACTATAGAAGTCAATAGCTGTTTTTTCTAATAGTGTATCCTCCTTTATGTTTAGCAGAAGAAAGCAACTCAGACAGATTTAGAGCAAGTTGAGGATGAGTGAATGATGGCTGAATTTTACGCTGGGGTGATAGTAGGGTTGTAACGGTATGAATTTTTCACGGTATGATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa18626
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000039786 | None | None | 218 | None | 6 |
| ENSDART00000103033 | Nonsense | 574 | 935 | 12 | 20 |
| ENSDART00000130466 | Nonsense | 574 | 935 | 12 | 19 |
Genomic Location (Zv9):
Chromosome 25 (position 8870163)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 25 | 8565228 |
| GRCz11 | 25 | 8642296 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTGTTTTGATTGCAGTCCGAGGACAAAACTGTGTTGTTTGCGGTGGGAT[C/A]GACACTGGTAAACTGCACCAAYAGCTACGATGTRGAGAAGCCAGACCCGC
Long Flanking Sequence:
GCTAACCACTGAGCCACTGTTGCCCTGTTTTAGTTTTTAGTCTTGGTAATTAATCTTTTAATTTAAAATTGAGGAGTGTTTACTAATCAAAGAGTCAGATCTATCAATTGAAATCATTGTCGTTTAGTTTTTGTAGCTCCAGCAAACGCATCTATTTGTGCATGTGTTTACATGTAATACATATTAAGTCCATTTAGCATGTGCATGTGGCTGTCTTTTTCTCTTTCCCAGATGGCTCTGCAATGAATCTCTTCCTCCAGCATCGCGGCGCTGGGCCATCGAGGGTCTGGCTTACCTCACGCTGGACGCCGATGTCAAAGAGGACCTGGTTGAGGACAAGAAAGCTCTTCAGGCCATGTTTGAGCTGGCCAAGGTTTCGCTTTTTCTGCAGTTTTGGAGATAAACGTCCGCTTATTATGCTAATCCTCCTCGGCTCCTTAAACTCGTGTTTTTGTTTTGATTGCAGTCCGAGGACAAAACTGTGTTGTTTGCGGTGGGAT[C/A]GACACTGGTAAACTGCACCAACAGCTACGATGTGGAGAAGCCAGACCCGCAGATGGTGGAGCTAGCTAAATATGCTAAACAACATGTACCAGAGGAGCATCCAAAGGTGATTTATGCGGATAGGATTGTTATGTTGGTCAAAAATGAACTTATTGTTATTAATAATTTATGCTTGTTAAGTTTTAAAATCCATATATTGTCTTTTTTAGGATACAGCAAAATTATTCAGTGGCTGTTAAGCTCCAAAAAGCAGCATAAATGTAACACTTTAAATTAATTAACAAAAGTCGATCGTTATTTTGAACTACTTGTTTCCTTTATTTTTTGTTATTTTTATATATTTCATGTAATTTATTTGGTCTTAGTAATTGATTTATTATTTGTTATGTCATAGATTATTTAATATTTAGTTTGCTTTGGCAATGCTTTAATACATATGTATATATACAGTTGAAGTCAGAATTATTAGCCCCCTTTTGAATTTTTTTACTTTTTAAAAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa44243
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000039786 | None | None | 218 | None | 6 |
| ENSDART00000103033 | Nonsense | 601 | 935 | 12 | 20 |
| ENSDART00000130466 | Nonsense | 601 | 935 | 12 | 19 |
Genomic Location (Zv9):
Chromosome 25 (position 8870083)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 25 | 8565148 |
| GRCz11 | 25 | 8642216 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTGGAGAAGCCAGACCCGCAGATGGTGGAGCTAGCTAAATATGCTAAA[C/T]AACATGTACCAGAGGAGCATCCAAAGGTGATTTATGCGGATAGGATTGTT
Long Flanking Sequence:
TACTAATCAAAGAGTCAGATCTATCAATTGAAATCATTGTCGTTTAGTTTTTGTAGCTCCAGCAAACGCATCTATTTGTGCATGTGTTTACATGTAATACATATTAAGTCCATTTAGCATGTGCATGTGGCTGTCTTTTTCTCTTTCCCAGATGGCTCTGCAATGAATCTCTTCCTCCAGCATCGCGGCGCTGGGCCATCGAGGGTCTGGCTTACCTCACGCTGGACGCCGATGTCAAAGAGGACCTGGTTGAGGACAAGAAAGCTCTTCAGGCCATGTTTGAGCTGGCCAAGGTTTCGCTTTTTCTGCAGTTTTGGAGATAAACGTCCGCTTATTATGCTAATCCTCCTCGGCTCCTTAAACTCGTGTTTTTGTTTTGATTGCAGTCCGAGGACAAAACTGTGTTGTTTGCGGTGGGATCGACACTGGTAAACTGCACCAACAGCTACGATGTGGAGAAGCCAGACCCGCAGATGGTGGAGCTAGCTAAATATGCTAAA[C/T]AACATGTACCAGAGGAGCATCCAAAGGTGATTTATGCGGATAGGATTGTTATGTTGGTCAAAAATGAACTTATTGTTATTAATAATTTATGCTTGTTAAGTTTTAAAATCCATATATTGTCTTTTTTAGGATACAGCAAAATTATTCAGTGGCTGTTAAGCTCCAAAAAGCAGCATAAATGTAACACTTTAAATTAATTAACAAAAGTCGATCGTTATTTTGAACTACTTGTTTCCTTTATTTTTTGTTATTTTTATATATTTCATGTAATTTATTTGGTCTTAGTAATTGATTTATTATTTGTTATGTCATAGATTATTTAATATTTAGTTTGCTTTGGCAATGCTTTAATACATATGTATATATACAGTTGAAGTCAGAATTATTAGCCCCCTTTTGAATTTTTTTACTTTTTAAAATATTTTCCAAATGATGTTTAACAGAGCAAGGAAATTTTCACAGTATGTCTGATAATATTTTTTCTTCTGGAGAAAGTCTTA
Associated Phenotype:
Not determined