Busch Lab

ZMP

ndrg3b

Ensembl ID:
ENSDARG00000010052
ZFIN ID:
ZDB-GENE-030131-5606
Description:
N-myc downstream regulated family member 3b [Source:RefSeq peptide;Acc:NP_956091]
Human Orthologue:
NDRG3
Human Description:
NDRG family member 3 [Source:HGNC Symbol;Acc:14462]
Mouse Orthologue:
Ndrg3
Mouse Description:
N-myc downstream regulated gene 3 Gene [Source:MGI Symbol;Acc:MGI:1352499]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa24278 Nonsense Available for shipment Available now
sa32432 Essential Splice Site Available for shipment Available now
sa18512 Essential Splice Site Available for shipment Available now
sa10361 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa24278
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010258 Nonsense 6 371 2 16
ENSDART00000144965 Nonsense 6 371 2 16
ENSDART00000147799 Nonsense 6 148 2 7

The following transcripts of ENSDARG00000010052 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 15030229)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 15162162
GRCz11 23 14918239
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCTCTTTCTAGTGACGGGCAGCTGTCAGGCTTGATGATGGATGAGTTA[C/T]AGGATGTGCAGTTGACCGAGATCAAACCCCTCTTGACGGACAAGGTGAGT
Long Flanking Sequence:
CGTTTAATACACCGGCCAAGCATTCGTATCTGCTTTTGCTCGCTTTCTTTCTGCACAAGCACAATGATATTTTAACTTCTGAAGGAGAACAGAAGACACACAACCTTTTTTTTTTTTGTGACACCAAGCTTCACCAAGTCACCCAGCGACCATTATAACCGTGACATAAGCCTACATAATGTCCTTACTGAAACAGTTGCATGCATTGACCTTCAGGATGACCACGGAGAGTTAAATCATGAATTAAACATGCGCTCATCTGAATTCTGTTAACAAGGACAATGGCGGTTATTACACAGGGTGTTAAACATCAATTCTCTCTCTCTCTCTTTCACTCTCTCACACACGCTGTGCCCTGTTTACTGTAATCCTGTATTCATGAGCATTTGGCTGGCAGGTCAATAAATCAGCCCTCACTGTAATGATGTACTAATCCATTCCTGCCCTGTCTTTCTCTTTCTAGTGACGGGCAGCTGTCAGGCTTGATGATGGATGAGTTA[C/T]AGGATGTGCAGTTGACCGAGATCAAACCCCTCTTGACGGACAAGGTGAGTTTACACACATCATACAAGCATCTTATTGCCAACGTCAGCATTTCTCTTCTCCGTCTTTAACCGCGATTCGACCCTCCACTCCAGTTCTTTCACTCTGATTGGCACTACTGGATTGGGGCTCATCAAAGTGCTCGTCTTAGGGCCTGTTCCCTTGGAGACCGAGCCGTACCGGAGCAATGAGATCAGAGAGATGATGTATGAATGTCCTCAGATCCTAATCTCGCAGCTGCTGATATCACTAGCAGCAATGAGATGGTGTTAGAAAAATCTTCCTGACAGAGGTCAAGAACAAGAGATTGTTTGTTTGTTTTTGCTTGGATTAACCCTGTAAAGCAGAGAAGAGTATAAACTGAGCTCGGAGCCAGCTCCAATTGAGTGGGATTTGAGCTCCAAGCGAGATCCTAGGGGTTTTGTTTGTTTAATGTCTTGTACATGACACTGAGTTCAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32432
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010258 Essential Splice Site 253 371 None 16
ENSDART00000144965 Essential Splice Site 253 371 None 16
ENSDART00000147799 None None 148 None 7

The following transcripts of ENSDARG00000010052 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 14965171)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 15097104
GRCz11 23 14853181
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGAGAGGCCCGTTCTGGGAATGAACGAAAATGCAGTTAAAACGCTGAAG[T/C]AGGTTCATTGGTTGTCTTTTTCTTTTTAGGGTGTCTTTTAAAATGTCTTC
Long Flanking Sequence:
ATGTGCTTCTGGTTTTACCTCTGAAGTTGTAGTATACCATACATGCGCGTACCTGTTTTCATTGAATTATATGCTTTATCAGAAACCAACTAAATAAAATTATTTAAAAATCAAAGAGCATAGTAATTAAAGCCACTTAATTTAAAGTGGGACCCAAAAGCTATGTAATAACCTGCAGTACCACTCCATGATTTCCTCAATAAGTATTTCAATCGTTGCCCTATAAAGAGTTAAAGACTACGCTTTTCTTCCTCAGGATGAGCTGACGGAGAACCAGGAGATTATCCAAACATACCGCCTGCACATCGCTCAGGACATCAATCAGGATAACCTGGCGCTCTTCTGCCAGTCCTACAACAGGTGACAGGATCAAAACACATTGATTATTGGCAAATGAGCTGATCTTAACTGGATTTTCTTCTCTTTACTGCAGTCGTCGAGATCTGGAGATTGAGAGGCCCGTTCTGGGAATGAACGAAAATGCAGTTAAAACGCTGAAG[T/C]AGGTTCATTGGTTGTCTTTTTCTTTTTAGGGTGTCTTTTAAAATGTCTTCAATTTGCTGAAATATTGTGTTGTAGGTCATAAATGTCCCTTGAAGTATAATGTCCATTTTTATTTGATGTTTGATGAATTCTCAACCGAAACCAAAGAGAGTGTGGGATATGGTGGAGCTTCTACCCTTTAAAAAAAACAAAATACATTTTTATATCAGTTTTATATCTTCTAAAGGAGAATTTGTCACTGTTTTGTCACTGCCCTATTTTTCTAATTGAAAACCTTAGAAAATCTAAACATTTTTGTGCTGATAGGCTTCAAAATCCATTGCATGTTAAGGGATAAACTATTATTTTACTGCTTATTTGTATATACATACAGATGCCATTAAACCAGGCTGGAGCTCATATATATATAAAAAAAAAAAAAATATATATATATATATATATATACATAAAATCTGAAAGGTTGAACAGAAGTGCTGCAACATGTTGCAAAAAGCAATGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18512
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010258 Essential Splice Site 270 371 None 16
ENSDART00000144965 Essential Splice Site 270 371 None 16
ENSDART00000147799 None None 148 None 7
ENSDART00000010258 Essential Splice Site 270 371 None 16
ENSDART00000144965 Essential Splice Site 270 371 None 16
ENSDART00000147799 None None 148 None 7

The following transcripts of ENSDARG00000010052 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 14963568)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 15095501
GRCz11 23 14851578
KASP Assay ID:
2261-7465.1 (used for ordering genotyping assays)
KASP Sequence:
TCCTGCCYTGCTGATTGTTGGAGACACATCACCAGCGGTAGAGGCTGTGG[T/G]GAGTGACTAATCAAAAAANTGACCTGTTACGTCTACTGGCAMKGAGAAAG
Long Flanking Sequence:
ATAGTCGATATTGTGTTCAAAGATGTGTAAGAAATTGTTCAAAATGATCATTTATCCCTCAAGCAGTTAAGTTTTTAAATTCCTCTTCTCCTAGTAGCAGTTGATGGCCAGTAGACTGGATGTTGTATACTGTAAATAAAATTTCCCTACAGGGACAAATTAAGTTAACTAACTAATTAGAGTTTGCTTGTTTTCACACATGATTAAAAAAGAGGCTAAGAAATATCGAAATTAGATTTTTTGGAAGGGATTCCAATTAACAATCTTTTCCACTGGCCATTAGAAAAAAATCCTTAAGTGTTTAGTAATGTAAAGTCTGATTTTTTTTTTTCATGATGGTCTTGAAGGTCTTAAAAAGTCTTAAATTTGACTTGTTTGACCCTGTTTGTTATTGTTTTGATAATGCCTATACTTACACTGTGAGGCCTGTCTTCCTCTGCTGTTTAGGTGTCCTGCCTTGCTGATTGTTGGAGACACATCACCAGCGGTAGAGGCTGTGG[T/G]GAGTGACTAATCAAAAAAATGACCTGTTACGTCTACTGGCAATGAGAAAGAACATGTTGTGCTTCCTGAAAGAGTGTGCACTGACATCACGTCTTAAAAGAGCAGATAGCATGTTTTGCAATTTGTGTTTGTTTATGCTAGTGCATCACTTATGACAAGAAATGTCACATATGGGTCAAAGGTGATAAGGTTTTAATGTAATAATAATGTTAAATAATAATAATGTTAAACACAGCTTTTCTTTTAGTGCATGTGTGCTGCAAAATATAATGACTCAGGTTAGTCTCACTCAGTAGACATCAAGTCAAATAGAAATCATGAAGCAAGAAGAATTATATAACCTGATAAGTGTTTATTTAGGAATGACAATGTAGCCCTAAAATATTATTATTATTATTTTTAGTCTTTTTTTTAAGTAAAGCTCAAATTATGTGGTTTAATTTGTACATAAATGCATTGTTCGTGTTGAATGATGATTGGATATAATTGTATCTATGTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10361
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000010258 Essential Splice Site 270 371 None 16
ENSDART00000144965 Essential Splice Site 270 371 None 16
ENSDART00000147799 None None 148 None 7
ENSDART00000010258 Essential Splice Site 270 371 None 16
ENSDART00000144965 Essential Splice Site 270 371 None 16
ENSDART00000147799 None None 148 None 7

The following transcripts of ENSDARG00000010052 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 14963568)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 15095501
GRCz11 23 14851578
KASP Assay ID:
2261-7465.1 (used for ordering genotyping assays)
KASP Sequence:
TCCTGCCYTGCTGATTGTTGGAGACACATCACCAGCGGTAGAGGCTGTGG[T/G]GAGTGACTAATCAAAAAANTGACCTGTTACGTCTACTGGCAMKGAGAAAG
Long Flanking Sequence:
ATAGTCGATATTGTGTTCAAAGATGTGTAAGAAATTGTTCAAAATGATCATTTATCCCTCAAGCAGTTAAGTTTTTAAATTCCTCTTCTCCTAGTAGCAGTTGATGGCCAGTAGACTGGATGTTGTATACTGTAAATAAAATTTCCCTACAGGGACAAATTAAGTTAACTAACTAATTAGAGTTTGCTTGTTTTCACACATGATTAAAAAAGAGGCTAAGAAATATCGAAATTAGATTTTTTGGAAGGGATTCCAATTAACAATCTTTTCCACTGGCCATTAGAAAAAAATCCTTAAGTGTTTAGTAATGTAAAGTCTGATTTTTTTTTTTCATGATGGTCTTGAAGGTCTTAAAAAGTCTTAAATTTGACTTGTTTGACCCTGTTTGTTATTGTTTTGATAATGCCTATACTTACACTGTGAGGCCTGTCTTCCTCTGCTGTTTAGGTGTCCTGCCTTGCTGATTGTTGGAGACACATCACCAGCGGTAGAGGCTGTGG[T/G]GAGTGACTAATCAAAAAAATGACCTGTTACGTCTACTGGCAATGAGAAAGAACATGTTGTGCTTCCTGAAAGAGTGTGCACTGACATCACGTCTTAAAAGAGCAGATAGCATGTTTTGCAATTTGTGTTTGTTTATGCTAGTGCATCACTTATGACAAGAAATGTCACATATGGGTCAAAGGTGATAAGGTTTTAATGTAATAATAATGTTAAATAATAATAATGTTAAACACAGCTTTTCTTTTAGTGCATGTGTGCTGCAAAATATAATGACTCAGGTTAGTCTCACTCAGTAGACATCAAGTCAAATAGAAATCATGAAGCAAGAAGAATTATATAACCTGATAAGTGTTTATTTAGGAATGACAATGTAGCCCTAAAATATTATTATTATTATTTTTAGTCTTTTTTTTAAGTAAAGCTCAAATTATGTGGTTTAATTTGTACATAAATGCATTGTTCGTGTTGAATGATGATTGGATATAATTGTATCTATGTTT
Associated Phenotype:
Not determined