Busch Lab

ZMP

itgb3a

Ensembl ID:
ENSDARG00000056767
ZFIN ID:
ZDB-GENE-071207-1
Description:
integrin beta 3a [Source:RefSeq peptide;Acc:NP_001032312]
Human Orthologue:
ITGB3
Human Description:
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) [Source:HGNC Symbol;Acc:6156]
Mouse Orthologue:
Itgb3
Mouse Description:
integrin beta 3 Gene [Source:MGI Symbol;Acc:MGI:96612]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa18375 Essential Splice Site Available for shipment Available now
sa18576 Nonsense Available for shipment Available now
sa40040 Nonsense Mutation detected in F1 DNA Not yet available
sa40041 Nonsense Mutation detected in F1 DNA Not yet available
sa33142 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa40042 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa18375
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025358 Essential Splice Site 377 820 7 15
Genomic Location (Zv9):
Chromosome 3 (position 19517869)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 19480904
GRCz11 3 19630644
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TATCAACCYCATCTTTGCTGTAACCAGCAATGTGGCTCCACTGTATCGTG[T/C]RAGTTTCTGCAMTTTGTCTAWCATCTGTCTATATAACANTTACACMCGTT
Long Flanking Sequence:
TCACTTTACAAGCACAAGTCCTTTGACAGACACCCATATGCTTCATACTAACTTCTTGATTGTTCTTCATTTGATTCAAAATGAAGAGCCTGATGTATGTGGTATATCTTTCAAAAACAGAAATAATGATTGCAAATTTGCCCTTTTTAGTCATCAAACTCAGAGCACAGCTAAGGCTGTTTAATTGTGTTGTCTTACAATAAATATACAGTAAATGTAAGTTAAAGTGTCACTGACATAATCTGTTCACTTTGGCAATGAGGTCTTAAAATGTATGAAAAGTGTCTTTAAAAGGTTTTTAAAAGGTATTAAATTTATCTTAATGATTCCTGTATATACCGTTGGATGGATGGTTGGATGGTTGGATGGATGTCTGATAGTGCACATATTTTTGTATTTGTAGGACTACCCTTCAGTTGGCATGATCACGGATAAGATATCTGAGAACAATATCAACCTCATCTTTGCTGTAACCAGCAATGTGGCTCCACTGTATCGTG[T/C]GAGTTTCTGCACTTTGTCTATCATCTGTCTATATAACATTTACACACGTTTATGGGAAATGTCCTGTTTCTCACAGAACTACAGTGAGCTGATTCCAGGCTCAACAGTGGGAACGCTCACTAAAGACTCATCAAATGTTGTGCAACTCATTCTGGAATTGTATGCGGTAAGTCACTGCGCCAGGAGTTATACCTCGGTGTGAGTTCTGAGAATTGGTTACTTTTTACAACATTTTAGCAAATTTTAAAGTTACTTTTATTAAGTTTTATTAAGGTTTTTTCTTTTCTTTTTTTCAGTTTATATGCTATGGTAATAACACCAGTAGTACTTAATAGTTAAGTAAATCCCATTATATCAATCAGCATTATAAGATATTGGGGAAATAAATCCCAGAAAAGGCTCACTTGAGGAAGAGAAACAAATAAAACAGCATAAAAAGGTGGGGGGTGCGTTGAAAGAGAAAAGAAGTGAATAAAGAGGAGAAAATATTAGGAAACATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18576
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025358 Nonsense 406 820 8 15
Genomic Location (Zv9):
Chromosome 3 (position 19518032)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 19481067
GRCz11 3 19630807
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACGCTCACTAAAGACTCATCAAATGYTGTGCAACTCATTCTGGAATTGTA[T/A]GCGGTAAGTCACTGYGCCAGGAGTTWTACCTCKGTGTGAGTTCTGAGAAT
Long Flanking Sequence:
AGCACAGCTAAGGCTGTTTAATTGTGTTGTCTTACAATAAATATACAGTAAATGTAAGTTAAAGTGTCACTGACATAATCTGTTCACTTTGGCAATGAGGTCTTAAAATGTATGAAAAGTGTCTTTAAAAGGTTTTTAAAAGGTATTAAATTTATCTTAATGATTCCTGTATATACCGTTGGATGGATGGTTGGATGGTTGGATGGATGTCTGATAGTGCACATATTTTTGTATTTGTAGGACTACCCTTCAGTTGGCATGATCACGGATAAGATATCTGAGAACAATATCAACCTCATCTTTGCTGTAACCAGCAATGTGGCTCCACTGTATCGTGTGAGTTTCTGCACTTTGTCTATCATCTGTCTATATAACATTTACACACGTTTATGGGAAATGTCCTGTTTCTCACAGAACTACAGTGAGCTGATTCCAGGCTCAACAGTGGGAACGCTCACTAAAGACTCATCAAATGTTGTGCAACTCATTCTGGAATTGTA[T/A]GCGGTAAGTCACTGCGCCAGGAGTTATACCTCGGTGTGAGTTCTGAGAATTGGTTACTTTTTACAACATTTTAGCAAATTTTAAAGTTACTTTTATTAAGTTTTATTAAGGTTTTTTCTTTTCTTTTTTTCAGTTTATATGCTATGGTAATAACACCAGTAGTACTTAATAGTTAAGTAAATCCCATTATATCAATCAGCATTATAAGATATTGGGGAAATAAATCCCAGAAAAGGCTCACTTGAGGAAGAGAAACAAATAAAACAGCATAAAAAGGTGGGGGGTGCGTTGAAAGAGAAAAGAAGTGAATAAAGAGGAGAAAATATTAGGAAACATTTCATTTTGTGGTGAAAGCAATAGGGAATCATTGAATCATTGACAGAAAAACATAAAGTCTGATACCCATACATACCCGAAGTGCCTAGTGACAATCTCCAGCCACAGTATCCCTCTTTGAGCCAACTAAATAACTCAGGCCACTGAGGTAAGACAAGCTATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40040
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025358 Nonsense 418 820 9 15
Genomic Location (Zv9):
Chromosome 3 (position 19520444)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 19483479
GRCz11 3 19633219
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGCCATTTGTCTTTGCAGAAAATCAGGTCTAAGGTTGAGCTGGAGCTGT[T/A]GAATGTGCCGGATGAGTTATCGCTGTCCGTCACTGCAACATGTCTGGATG
Long Flanking Sequence:
CACTGTGTCGATCATGTGACTCGATACTTGATTTAAAACTCAAAAGATGCAGCAACTGGAGCAAGAGCAGTGTCAATTGCAGCTTTCACCTGTTCTGCGATGGTAGAGGTTAGCTCGGTGATCAGAGTGGCACAGAGATTTTCTAGATCCAGCGGCAGCCTGCCGCCATGACTCTTTGTCGCAGCCGCCAACACTTTTTCTGCCTTTCAGACGCCATAAATCCTTCCAAACTGTATCTGTTTGATGCCCGATACAAATAGGAAACCACCAAGTGTGTTTAAAGATTCAAGCAGTCAGCTAAATATATTGAAAGACGAAATTGTTCGGGAGCTCACTTCAAGCGTGATTACCGACTCACAATCTTAACCGGATGTCGTTTCAGCTCATTTTAAATAAGTAGTTTGAACAAACAACAAACGTCATTTTTTTAAACGTATATTTGTATTGTTTGTGCCATTTGTCTTTGCAGAAAATCAGGTCTAAGGTTGAGCTGGAGCTGT[T/A]GAATGTGCCGGATGAGTTATCGCTGTCCGTCACTGCAACATGTCTGGATGATGAGGTCATTCCAGGAGTACGGTCCTGTGACGGACTCAAAATTGGAGATATGGTCAGCAACTGACGCATAAACACTGGAGAAAACCATGCTTGTTCCATTTACCAAAGTGCAGTGAGCCAAAGCAACACTTCATCAATATGTTTTATCTCTTATTTTTATTGAGTTGTGGTTAATAGTAAAAGTTAGTTTGTAAACAGACAAAAGTTTACAGTCATAACCTATAATGACAGACAAACCTGAAAGCTGCAACTGACCAATCAGGGTCAAGTATTTTAGAAAGCTGTGTATATGGGGTCGCACAACAGTTGAAATTATCGCACACCTGATGCACACATTTACATGTTATTTAAAATGAAACTATTCATATGGCACTCTGTGGTGTGGCAGGAATATGAACAGTGTTCTGAACCATTAATCCTAATCCTAAACCAAACCGTCATCCTAACGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40041
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025358 Nonsense 450 820 9 15
Genomic Location (Zv9):
Chromosome 3 (position 19520539)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 19483574
GRCz11 3 19633314
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGATGATGAGGTCATTCCAGGAGTACGGTCCTGTGACGGACTCAAAATT[G/T]GAGATATGGTCAGCAACTGACGCATAAACACTGGAGAAAACCATGCTTGT
Long Flanking Sequence:
TGCGATGGTAGAGGTTAGCTCGGTGATCAGAGTGGCACAGAGATTTTCTAGATCCAGCGGCAGCCTGCCGCCATGACTCTTTGTCGCAGCCGCCAACACTTTTTCTGCCTTTCAGACGCCATAAATCCTTCCAAACTGTATCTGTTTGATGCCCGATACAAATAGGAAACCACCAAGTGTGTTTAAAGATTCAAGCAGTCAGCTAAATATATTGAAAGACGAAATTGTTCGGGAGCTCACTTCAAGCGTGATTACCGACTCACAATCTTAACCGGATGTCGTTTCAGCTCATTTTAAATAAGTAGTTTGAACAAACAACAAACGTCATTTTTTTAAACGTATATTTGTATTGTTTGTGCCATTTGTCTTTGCAGAAAATCAGGTCTAAGGTTGAGCTGGAGCTGTTGAATGTGCCGGATGAGTTATCGCTGTCCGTCACTGCAACATGTCTGGATGATGAGGTCATTCCAGGAGTACGGTCCTGTGACGGACTCAAAATT[G/T]GAGATATGGTCAGCAACTGACGCATAAACACTGGAGAAAACCATGCTTGTTCCATTTACCAAAGTGCAGTGAGCCAAAGCAACACTTCATCAATATGTTTTATCTCTTATTTTTATTGAGTTGTGGTTAATAGTAAAAGTTAGTTTGTAAACAGACAAAAGTTTACAGTCATAACCTATAATGACAGACAAACCTGAAAGCTGCAACTGACCAATCAGGGTCAAGTATTTTAGAAAGCTGTGTATATGGGGTCGCACAACAGTTGAAATTATCGCACACCTGATGCACACATTTACATGTTATTTAAAATGAAACTATTCATATGGCACTCTGTGGTGTGGCAGGAATATGAACAGTGTTCTGAACCATTAATCCTAATCCTAAACCAAACCGTCATCCTAACGCTGATCTTATAGTAAGTAAATGTAGTTAATTACTTTTCATTTGGTACTTTATGTATGGTTAAACTGTAACAAGAACAAGGCGTGATGGCGCAGTGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33142
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025358 Essential Splice Site 453 820 10 15
Genomic Location (Zv9):
Chromosome 3 (position 19521800)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 19484835
GRCz11 3 19634575
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTACCATGTGAATTGACCTTTAACTTCTTTTTCTCACTCTCCATGAAA[G/A]GTTTCGTTCAGCATTGAGGCCAAACTTCACGGCTGCCCCAAACAGAAGAG
Long Flanking Sequence:
GTTAATCACACGACTAACACGTCTTGCGCCATATAACGCTAGGTGTATGATCGGGCCCTTTACTTTGGTCCACTTGAGTATTAGTAGACTGTCTGCTTAATACCTGTTGATATTCTCCTTTAACAGACATTTAACTGACTATAAGAAACTTTGCAAGTACATCTCAACATACACTAACCTCAACAGTCTACTTAAATCTAATGAGAATTAGCTGTAGATGCAATGTAACTTAAATTTGACAAACGAACCATCAAAATAAAGTGTGACCGAGACTGAATATTTATACATATAATGAACTATGTGGTCACATTTAGAGATTATTGATTTGAATCATTGTTCAATCATCAATTTTATTATTCATATTAAATGCTCTTATCCAAAGCACTTTGCATTTAAGCAGTACATTTTGTCAACCTCATAACTTCATCATTTTTTCTCCATCCTCTACTGTTTTACCATGTGAATTGACCTTTAACTTCTTTTTCTCACTCTCCATGAAA[G/A]GTTTCGTTCAGCATTGAGGCCAAACTTCACGGCTGCCCCAAACAGAAGAGTCAGACTTTTACAGTGAAGCCAATTGGTTTTAAAGACGCTCTTCAGGTCACTGTGGACTTTGCTTGCGATTGTACCTGTCAGCAGAACTCGGTGCCTGCCAGCCCATACTGTCATGAAGGCAATGGGACGCTGGAGTGCGGCACGTGCCTGTGCGACCCGGGCCGACTGGGCTCCCGATGCGAGTGCAGTGAGAGCGAATATAAACCCACTCAACAGGACAGCTGTAGCCCCAGTCCAGAGGCACGGACCTGTAGTGGACGTGGAGACTGTGTGTGCGGCCAGTGTGCCTGCCGCTCAAGCAATTTTGGAAAAGTTTGGGGTCCGTTCTGTGAATGTGATGACTTCAGCTGCCCTCGCTCTAAAGGACAACTGTGCTCAGGTGAAGCTGCAAACACACATAATTTTTTGTGCTTACATATACAACTCCAAATCAGAAAAAGTTAGACAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40042
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000025358 Essential Splice Site 596 820 10 15
Genomic Location (Zv9):
Chromosome 3 (position 19522232)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 19485267
GRCz11 3 19635007
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAATGTGATGACTTCAGCTGCCCTCGCTCTAAAGGACAACTGTGCTCAGG[T/C]GAAGCTGCAAACACACATAATTTTTTGTGCTTACATATACAACTCCAAAT
Long Flanking Sequence:
TTTCTCCATCCTCTACTGTTTTACCATGTGAATTGACCTTTAACTTCTTTTTCTCACTCTCCATGAAAGGTTTCGTTCAGCATTGAGGCCAAACTTCACGGCTGCCCCAAACAGAAGAGTCAGACTTTTACAGTGAAGCCAATTGGTTTTAAAGACGCTCTTCAGGTCACTGTGGACTTTGCTTGCGATTGTACCTGTCAGCAGAACTCGGTGCCTGCCAGCCCATACTGTCATGAAGGCAATGGGACGCTGGAGTGCGGCACGTGCCTGTGCGACCCGGGCCGACTGGGCTCCCGATGCGAGTGCAGTGAGAGCGAATATAAACCCACTCAACAGGACAGCTGTAGCCCCAGTCCAGAGGCACGGACCTGTAGTGGACGTGGAGACTGTGTGTGCGGCCAGTGTGCCTGCCGCTCAAGCAATTTTGGAAAAGTTTGGGGTCCGTTCTGTGAATGTGATGACTTCAGCTGCCCTCGCTCTAAAGGACAACTGTGCTCAGG[T/C]GAAGCTGCAAACACACATAATTTTTTGTGCTTACATATACAACTCCAAATCAGAAAAAGTTAGACAGTTTAGAAAACGCAAATAAAAAAGTAGTGCTTTCAAAAGTTACTTTGATTTTGTTCATTGCAGACAATACAACAAACATTATTTAATGTGTTCCTCGTGATTTTTTTTTATAATAAACACATATTTAAATTTTGATTCTCGCAACACATTTAAAAAAAACATTTTAAACATGAAAACATTTACGACTTTGTATTATTGCTGTTTTATTTCACAACATTTAAAAGACGTCTAGGGACTGACACCAAGTGATGAAGTGTTTCAGGTAAAGTTTTGTCCCAATTTTCCCTGCAAACAAGTCTGAAGTTGGCCAACAGAACAGGGTCTTTGTTTTTTTTTTTTTTTTGTTTTTTTGTTTTTTACACATTCTCTATTGAAGACAGGTTGGGACTGCAGGCAGGCCAGTTAAGTACCTGTATCCTCTGTCTTTTATTTTT
Associated Phenotype:
Not determined