Busch Lab

ZMP

aox3

Ensembl ID:
ENSDARG00000071475
ZFIN ID:
ZDB-GENE-001205-2
Description:
Novel protein similar to vertebrate xanthine dehydrogenase (XDH) [Source:UniProtKB/TrEMBL;Acc:Q1LW04
Human Orthologue:
AOX1
Human Description:
aldehyde oxidase 1 [Source:HGNC Symbol;Acc:553]
Mouse Orthologues:
Aox1, Aox3, Aox3l1, Aox4
Mouse Descriptions:
aldehyde oxidase 1 Gene [Source:MGI Symbol;Acc:MGI:88035]
aldehyde oxidase 3 Gene [Source:MGI Symbol;Acc:MGI:1918974]
aldehyde oxidase 3-like 1 Gene [Source:MGI Symbol;Acc:MGI:3529596]
aldehyde oxidase 4 Gene [Source:MGI Symbol;Acc:MGI:1919122]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa574 Nonsense Available for shipment Available now
sa18330 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa574
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Nonsense 670 1241 18 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14236357)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14067465
GRCz11 22 14092242
KASP Assay ID:
554-0484.1 (used for ordering genotyping assays)
KASP Sequence:
TCTACATGGAAACTCAGGGAGTGATTGCAATTCCTACAGGAGAAGCAAGT[G/T]AAATTGAGCTATATGTTGCCAGTCAGCATGCAGCTTACACTCAGGTTTGT
Long Flanking Sequence:
TCATTTCAGGTCATTTGTGTGGGGCAGATTATTGGTGCGATTGTAGCTGAGACTAGAGAACAAGCTAAACGAGCAGCTCAGCAAGTAGACATTACTTACCAGGATATGCAACCTGTCTTTTTCACAATTGAGGTATTTCAATGCATAAGTATATCCATAAAACACTTCATAATGGGGAAATAAATGTTTATCACACACATCTAATCATACTAATCAAAAAAATTTTTTTTTTAATTCTAGGAGGCTATTGAACACGAGTCATTTTTTGACCCCAAGAGAAAGCTGGAAAGAGGAAATGTGGAAGAAGGTTTTGCAAAGGCAGACCAAATTCTAGAGGGTTTGTGTAAACCTGATTCGAAGTCCTTTTAAAACTGTGCTTTGACTTTTAGCTCAACTGTGCATAATCGTATTATATCACAGGTGAGATGTATATGGGTGGCCAGGAACACTTCTACATGGAAACTCAGGGAGTGATTGCAATTCCTACAGGAGAAGCAAGT[G/T]AAATTGAGCTATATGTTGCCAGTCAGCATGCAGCTTACACTCAGGTTTGTATTATGATTCACTATAAATATATTAATGTTTTAGATAATATGAATATTTAAGGAGAATCCTATAAAAAACAACAACAGAATTTACAATCTTCGGGCTAATTTTCTTTTAAAACAGGAAGTGGTGGGAATCACTCTCGGCATTGACTCCAACAAGATCACGTGTCATGTAAAGAGGCTGGGAGGTGGTTTTGGTGGTAAAGTCATGAAGATTGCATCATTATCTGCTATCGCTGCTACGGCTGCCATAAAGTAAATCAAACTAAGACCCTTACCTTTTTTACAGAATCGTTTCATTTCATTCTATTGAGCATTCACTTGTATTGCTTATATCATGCATTGTTGGGAAGAAAAGTTTTCTATGGCTTATAAAAATATGAAATGTTCAATGCTAATGCTATTTATTGACTGTATATTAAAAATTTAACCACAGGACTGGCCATGCTGTGCGAT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa18330
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000105717 Essential Splice Site 758 1241 20 32

The following transcripts of ENSDARG00000071475 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 22 (position 14235788)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 14066896
GRCz11 22 14091673
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGACATGCTCATCACCAGTGGAAGATCTCCTTTCTTGGGGARGTACAAG[G/A]TAATGAGATGTTATGAGTGATATYTGTGATTGAACAGCTGTGCTGCATCA
Long Flanking Sequence:
TATATTAATGTTTTAGATAATATGAATATTTAAGGAGAATCCTATAAAAAACAACAACAGAATTTACAATCTTCGGGCTAATTTTCTTTTAAAACAGGAAGTGGTGGGAATCACTCTCGGCATTGACTCCAACAAGATCACGTGTCATGTAAAGAGGCTGGGAGGTGGTTTTGGTGGTAAAGTCATGAAGATTGCATCATTATCTGCTATCGCTGCTACGGCTGCCATAAAGTAAATCAAACTAAGACCCTTACCTTTTTTACAGAATCGTTTCATTTCATTCTATTGAGCATTCACTTGTATTGCTTATATCATGCATTGTTGGGAAGAAAAGTTTTCTATGGCTTATAAAAATATGAAATGTTCAATGCTAATGCTATTTATTGACTGTATATTAAAAATTTAACCACAGGACTGGCCATGCTGTGCGATGTGTACTAGAACGTGGAGATGACATGCTCATCACCAGTGGAAGATCTCCTTTCTTGGGGAGGTACAAG[G/A]TAATGAGATGTTATGAGTGATATTTGTGATTGAACAGCTGTGCTGCATCACAACGGTATAATTCCTGCCTTTTTCCTACAGATTGGCTATATGAATGACGGAACAATCCTGGCTGCTGATATCACATACTACAGTAATGGAGGATGCACTCTTGATGAATCCTCTTTTGTATGTTGGTTTTTAAGAAATTTAACATGTATAAATTGGTAATAGCTGATGAAATGTTGATACAAGTTAACATGTATCAAAGTACATGTAATTCCCAAGTAGATCAGTCTCCAAATCACAAACGGTGTATTTATATGTAATTTATGACCAGATTATGGAGAAAGCTCTTCTTCACATGGATAATGGCTACAAGATCCCTAATCTACGTGGACGTGGACTGGTGTGCAAGACCTTCTTACCTTCATACACAGCCTTCCGTGGATTTGGTGGACCTCAAGGGTTGACCATTATTGAGAGTGTGCTACATGAGGTGGCGGTCAAGTGTGGCCTAC
Associated Phenotype:
Not determined