ZMP

med12

Ensembl ID:

ENSDARG00000056800

ZFIN ID:

ZDB-GENE-060125-1

Description:

Mediator of RNA polymerase II transcription subunit 12 [Source:UniProtKB/Swiss-Prot;Acc:Q2QCI8]

Human Orthologue:

MED12

Human Description:

mediator complex subunit 12 [Source:HGNC Symbol;Acc:11957]

Mouse Orthologue:

Med12

Mouse Description:

mediator of RNA polymerase II transcription, subunit 12 homolog (yeast) Gene [Source:MGI Symbol;Acc:

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa18291	Nonsense	Available for shipment	Available now
sa6342	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa18291

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000079327	Nonsense	17	302	1	5

Genomic Location (Zv9):

Chromosome 14 (position 24569812)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	14	23369420
GRCz11	14	23666665

KASP Assay ID:

2260-7516.1 (used for ordering genotyping assays)

KASP Sequence:

TCATGCAGTAYGCTCCAGGCATGACCCCTGATCTCCCACTGAGCATGGGA[C/T]AAACAAACATGTCATATCGAATGGGCTACCAAGCTCCAATGAACATGTAT

Long Flanking Sequence:

GTATCAACTAAGCAGAAGATTTCTCCATGGGATGTGTTCGAGGGACTAAAGCACTCTGCTCCACTCTCCTGGGGCTGGTTCGGAACCATACGGGTCGACCGAAAAGTCACTAAGTTTGAAGAGCAGCAGCGGCTCCTGCTTTACCACACACACATCAAGCCCAAGCAACGCAGTTACTACCTGGCGCCCCTCAACCTGCCCCAAGAAGAAGAGGAACCACTCACTCCTGTGCCTCCCGAGCCAGACAAGAAGCTGGACACAGCGAAAGTGGAGAAAAGCGTCTCCAGTGTCCCGACTAAGAAAAAGAAAAAGAAACCTGCATCGACAGTTAAACAAGAGGTACAACCAGAACCAATTGTTTTTTTTCTGCAACATATTTATGAGGTATTCATTTGATGCAAACCCAGACATTGTTTTCTGTGATCTAGGACTACAAGCCACACAACACAGTCATGCAGTACGCTCCAGGCATGACCCCTGATCTCCCACTGAGCATGGGA[C/T]AAACAAACATGTCATATCGAATGGGCTACCAAGCTCCAATGAACATGTATGCCCAGAACCAGCCTTTACCACCAGGTCAGCACAAATCATAGAATGTCTGAAGCTCTTGTTCTAACTTTTCTTTAAATAAAAGACAGAAGTTGTGACCTTTGACCACAAAACCATCTAATTTTGATTATCAATGCACATTAATTTCGATTTATTCAAATTTTGTACATCCGTGTTTCTTAATTTAATTCGCCAAACACATGACATGACAATTTGTCCACAACACGTGACAGGTAAGAGCTTGCTTTCTCTGATGAATCAAGTGTTTTCATTTCACCTATTTTGTGGTTACGATGAGTGCCGCAAGGAATCCATGTCTGATGCCATTAATCTTACATTTCTTTTTAACTTCGGCAAATCGATCTCTGCTTTAACACTTCCGTTGTCAGGTCTCGAAGGTTATGCACTTTTGTACCTTTATATTCCAAAGATTCCAACTTCATGATTAATTA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa6342

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000079327	Essential Splice Site	106	302	2	5

Genomic Location (Zv9):

Chromosome 14 (position 24572000)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	14	23371617
GRCz11	14	23668862

KASP Assay ID:

554-4509.1 (used for ordering genotyping assays)

KASP Sequence:

AACCCATGCCCAACATGGCTCAGGGGCAGATGCTCCGTCATCAGCTACAG[G/A]TCAGACTGGTGAGTCTGATTTTACTGATCAAGACCCCAGACCAAAAACAC

Long Flanking Sequence:

TTCTCTATGTGCCCCAGAACCGGAAGTACATCAATGCAGATTAATAATCAAAAGTTTTGTTTTTTTATTTTTATGGTCCAAAATGTATAAAAGGTTTCGAAAGAACATGATTTTTACCTAATATTCTAATGCATTGTTGGCTATTCATAGAATTATACACTTTCAATGGAAGACTAATTTTGTGGTCCAGGGCTACAATTCATGAAGCATTTGTTTTACTACTTTTAGTAATATAATATTCACATTGGACATCTGATCCTTATTTTTTTAATGTATTTCCTTCTATTTCCTTTTTTCCACCCTTAGGAGGTCCTGGTTTGGAGCCACCTTTTCGTCCTAGGGTTCCTATGAATAAAATGCCTCCACGTCCCAACTACACTATGCCTAATATGCAGACCGCTGGCATGGGCAACCTAATGGGAATGGAGAAGCAGTACCAGATGAACTATAAACCCATGCCCAACATGGCTCAGGGGCAGATGCTCCGTCATCAGCTACAG[G/A]TCAGACTGGTGAGTCTGATTTTACTGATCAAGACCCCAGACCAAAAACACACACGGTTTCCTTGTTTAATGTGTCTTACTGTTTCATGTGATTTGCAGTTTTGCATTTGAATTAGTGGTGCTTGTCATGACAGTGATGCTACACACAATTTAAACGCACATTTTGAAGTAAAATTATTTCACCAATAGAAACTTTCTCTAACAGACTCTGTTATTAAGGGTGTACTCACACTAGGCTATCTGAACCGTGCTCAGGCACGTTTGACTACCATTTCCCGATGCGTTTGACAACTATGAGTGTTTCGAATCAGGCCCAGATGTGGTTCAGTTGGCTGACTCTGGCCCAGTTAGAAGATGTGTGCCAAAGCGTGATTTAGTTGGGCTTTGGCCCGGTACGCTTGTAATGTGAGTACAAATCACACCTAAGTTTGAAGTCTGAAAACTGAAGCCCCGACATCAACTTTAAGGGACTATTTCATATGGATTTATGATTCATTATTA

Associated Phenotype:

Not determined