ZMP

zgc:56306

Ensembl ID:

ENSDARG00000037099

ZFIN ID:

ZDB-GENE-040426-975

Description:

insulin receptor substrate 2 [Source:RefSeq peptide;Acc:NP_956609]

Human Orthologues:

IRS1, IRS4

Human Descriptions:

insulin receptor substrate 1 [Source:HGNC Symbol;Acc:6125]
insulin receptor substrate 4 [Source:HGNC Symbol;Acc:6128]

Mouse Orthologues:

Irs1, Irs3, Irs4

Mouse Descriptions:

insulin receptor substrate 1 Gene [Source:MGI Symbol;Acc:MGI:99454]
insulin receptor substrate 3 Gene [Source:MGI Symbol;Acc:MGI:1194882]
insulin receptor substrate 4 Gene [Source:MGI Symbol;Acc:MGI:1338009]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa18282	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa18282

Status:

Available for shipment
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Availability:

Order Allele From ZIRC
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Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000053924	Nonsense	357	1032	1	2

Genomic Location (Zv9):

Chromosome 1 (position 28143406)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	28408833
GRCz11	1	29212764

KASP Assay ID:

2259-0667.1 (used for ordering genotyping assays)

KASP Sequence:

AAGCCCAATGACTGTTGGCCGGMACCACATGAGTAGATCTAATACWGTTT[C/A]AGTAGGCTGTCGGACATCAGAACCATCACTACTWAATCACAGCAGGTCCA

Long Flanking Sequence:

TTTTGTGAAACTTAACTCCGAGGTGGCATCAGTTACCCTACAGTTGATGAATATTCGTAGGTGTGGGCACTCTGATAGCTTTTTCTTTATTGAAGTTGGAAGATCAGCCTCTACTGGACCTGGAGAACTGTGGATGCAAGCAGACGATTCTGTGGTGGCACAAAATATACATGAGACAATTTTAGAAGCTATGAAAGCAATGAAAGAGCTGTCAGAGTTCAGACCCCGCAGCAAAAGTCAGTCATCAGGATCAAACCCCATTTCTGTACCCACTCGTCGGAACCTAAACAATTTACCTCCAAGTCAAACAGGGCTAGTGAGGAGGTCAAGGACGGACAGTACAGCAGCCACATCTCCCGTGACCAAATTTTCTTCTTGTCGAATACGGACTGCAAGTGAAGGGGAAGGTACCATGATCAGGCCAGTCTCTGTATCAGTATCTGAGAATGGAAGCCCAATGACTGTTGGCCGGCACCACATGAGTAGATCTAATACTGTTT[C/A]AGTAGGCTGTCGGACATCAGAACCATCACTACTTAATCACAGCAGGTCCATGTCTATGACCATGTACCACTCTCCCCCATCTGTTGTAAGTCCACTAAGTTTGTCTTCAATCAGTATGAATGGTTCTATCTCAAACAAAGCACACAGACCTTCCAGCTGTAGTGGTTCTGTTTCTGGGTCACCAAATGATTTTGGCTTTTTAACGTGTGAGGATTACAGTTCCAGCCCAGGGGATGTGAGGTACAACCTAGCAAACAGGAGTGACACTCCTTCTTCTCTGTCCAGCACACCACCCTTACGAGAAACCAGTGAACTCCATAGTTATATGGTGATGGACAGGCCATCCAACTTTTCACAGAACAAGACTAGCAGAGACATGTTGGATGTGGAGACATACAGGAAGAGGACATATTCTCTAACAACCCCACGGCAACAGATGGCACACTCCCAGTTATCTTCAGCGTCACTTGATGAATACATGTTGATGAGGGCTGCGAACA

Associated Phenotype:

Not determined