Busch Lab

ZMP

lmbrd2b

Ensembl ID:
ENSDARG00000017312
ZFIN ID:
ZDB-GENE-030131-7197
Description:
LMBR1 domain-containing protein 2-B [Source:UniProtKB/Swiss-Prot;Acc:Q6P4P2]
Human Orthologue:
LMBRD2
Human Description:
LMBR1 domain containing 2 [Source:HGNC Symbol;Acc:25287]
Mouse Orthologue:
Lmbrd2
Mouse Description:
LMBR1 domain containing 2 Gene [Source:MGI Symbol;Acc:MGI:2444173]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa8907 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa18217 Essential Splice Site Available for shipment Available now
sa10053 Essential Splice Site Available for shipment Available now
sa32345 Nonsense Available for shipment Available now
sa23925 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa8907
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
Genomic Location (Zv9):
Chromosome 21 (position 21364480)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22375973
GRCz11 21 22412609
KASP Assay ID:
554-7933.1 (used for ordering genotyping assays)
KASP Sequence:
GGATTCTGYCATATCCCACCAAGCAAAGAAGCAGACRGCATACACCTCTG[T/A]GAGTCTTTCAGCATTATGTACGATKATTTTAATATGCYAGCAAAAGCAAT
Long Flanking Sequence:
TTTATCTTCATATGAATATACTGAATATATATAGATATTGAACATTTTGTTCCTTTTTTAATTATTCAAATGTAATTTTGTTAATTTGGTCTGTTTTATTTAATTTCAATACACCAATGCTTAGAGTCTAACCTGTTGTTCATAATGTGATTTTGGCCTGTAGATGGCGTGCTTCATCACCATCTTTTTCCTCTGTACCTGCGTCTACTCTACTGTGTTTCGCATCCGAGTCTTCAACTACTATTACCTGGCCTCACATCACCAAACTGACGCCTACAGCCTGCAGTTCAGCGGCATGTGCGTTTCACAGATAAACAGTATTGTGAATGAATTAAGCTGAATTGTATTGTTCGTGTTTTCTCTGAAGCACAACACCTGTGTGATGTTTACTAGGCTTTTTTGCCGTTTGACTCCACCACTATGTCTAAACTTCCTGGGACTGATTCACATGGATTCTGCCATATCCCACCAAGCAAAGAAGCAGACGGCATACACCTCTG[T/A]GAGTCTTTCAGCATTATGTACGATTATTTTAATATGCCAGCAAAAGCAATCAGGCCATTTGAGATGTCTAATTATTATGCTTAATTGAATGTCATAGATCATGGGTTCCATGCGGGTCCTGTCCTTCATTGCCAATGGCTTCTACATCTATTACCCGATGTTGATCGTCATTCTCTGCATTGCTACATACTTCAGGTGTCTAATATTTTCTCAGAATCACCCAATGGTTTCATGTAACATGTGTATTATGAGTCAGATGTTATATGTAATGCGTATTATGTGTCAGATGTAATTTCTGACTGATTTATAGTAATTCTTTTTTATTACCGTCCAGTCTTGGCACACGCTGTCTGAACCTCCTGGGTTTCCAGCAGTTCATGGGAGAAAATGAAATGACCTCAGACCTCATAGATGAAGGCAGAGAACTCTTGCGCAGAGGTATACATTTATAAAGCATATATATAAAAATGTATATATATTTGAAAATTATGTTGTTTCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18217
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
Genomic Location (Zv9):
Chromosome 21 (position 21364480)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22375973
GRCz11 21 22412609
KASP Assay ID:
554-7933.1 (used for ordering genotyping assays)
KASP Sequence:
GGATTCTGYCATATCCCACCAAGCAAAGAAGCAGAMRGCATACACCTCTG[T/A]GAGTCTTTCAGCATTATGTACGATKATTTTAATATGCYAGCAAAAGCAAT
Long Flanking Sequence:
TTTATCTTCATATGAATATACTGAATATATATAGATATTGAACATTTTGTTCCTTTTTTAATTATTCAAATGTAATTTTGTTAATTTGGTCTGTTTTATTTAATTTCAATACACCAATGCTTAGAGTCTAACCTGTTGTTCATAATGTGATTTTGGCCTGTAGATGGCGTGCTTCATCACCATCTTTTTCCTCTGTACCTGCGTCTACTCTACTGTGTTTCGCATCCGAGTCTTCAACTACTATTACCTGGCCTCACATCACCAAACTGACGCCTACAGCCTGCAGTTCAGCGGCATGTGCGTTTCACAGATAAACAGTATTGTGAATGAATTAAGCTGAATTGTATTGTTCGTGTTTTCTCTGAAGCACAACACCTGTGTGATGTTTACTAGGCTTTTTTGCCGTTTGACTCCACCACTATGTCTAAACTTCCTGGGACTGATTCACATGGATTCTGCCATATCCCACCAAGCAAAGAAGCAGACGGCATACACCTCTG[T/A]GAGTCTTTCAGCATTATGTACGATTATTTTAATATGCCAGCAAAAGCAATCAGGCCATTTGAGATGTCTAATTATTATGCTTAATTGAATGTCATAGATCATGGGTTCCATGCGGGTCCTGTCCTTCATTGCCAATGGCTTCTACATCTATTACCCGATGTTGATCGTCATTCTCTGCATTGCTACATACTTCAGGTGTCTAATATTTTCTCAGAATCACCCAATGGTTTCATGTAACATGTGTATTATGAGTCAGATGTTATATGTAATGCGTATTATGTGTCAGATGTAATTTCTGACTGATTTATAGTAATTCTTTTTTATTACCGTCCAGTCTTGGCACACGCTGTCTGAACCTCCTGGGTTTCCAGCAGTTCATGGGAGAAAATGAAATGACCTCAGACCTCATAGATGAAGGCAGAGAACTCTTGCGCAGAGGTATACATTTATAAAGCATATATATAAAAATGTATATATATTTGAAAATTATGTTGTTTCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10053
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
ENSDART00000021682 Essential Splice Site 520 704 12 18
ENSDART00000134592 Essential Splice Site 552 736 12 18
Genomic Location (Zv9):
Chromosome 21 (position 21364480)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22375973
GRCz11 21 22412609
KASP Assay ID:
554-7933.1 (used for ordering genotyping assays)
KASP Sequence:
GGATTCTGYCATATCCCACCAAGCAAAGAAGCAGACRGCATACACCTCTG[T/A]GAGTCTTTCAGCATTATGTACGATKATTTTAATATGCYAGCAAAAGCAAT
Long Flanking Sequence:
TTTATCTTCATATGAATATACTGAATATATATAGATATTGAACATTTTGTTCCTTTTTTAATTATTCAAATGTAATTTTGTTAATTTGGTCTGTTTTATTTAATTTCAATACACCAATGCTTAGAGTCTAACCTGTTGTTCATAATGTGATTTTGGCCTGTAGATGGCGTGCTTCATCACCATCTTTTTCCTCTGTACCTGCGTCTACTCTACTGTGTTTCGCATCCGAGTCTTCAACTACTATTACCTGGCCTCACATCACCAAACTGACGCCTACAGCCTGCAGTTCAGCGGCATGTGCGTTTCACAGATAAACAGTATTGTGAATGAATTAAGCTGAATTGTATTGTTCGTGTTTTCTCTGAAGCACAACACCTGTGTGATGTTTACTAGGCTTTTTTGCCGTTTGACTCCACCACTATGTCTAAACTTCCTGGGACTGATTCACATGGATTCTGCCATATCCCACCAAGCAAAGAAGCAGACGGCATACACCTCTG[T/A]GAGTCTTTCAGCATTATGTACGATTATTTTAATATGCCAGCAAAAGCAATCAGGCCATTTGAGATGTCTAATTATTATGCTTAATTGAATGTCATAGATCATGGGTTCCATGCGGGTCCTGTCCTTCATTGCCAATGGCTTCTACATCTATTACCCGATGTTGATCGTCATTCTCTGCATTGCTACATACTTCAGGTGTCTAATATTTTCTCAGAATCACCCAATGGTTTCATGTAACATGTGTATTATGAGTCAGATGTTATATGTAATGCGTATTATGTGTCAGATGTAATTTCTGACTGATTTATAGTAATTCTTTTTTATTACCGTCCAGTCTTGGCACACGCTGTCTGAACCTCCTGGGTTTCCAGCAGTTCATGGGAGAAAATGAAATGACCTCAGACCTCATAGATGAAGGCAGAGAACTCTTGCGCAGAGGTATACATTTATAAAGCATATATATAAAAATGTATATATATTTGAAAATTATGTTGTTTCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32345
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021682 Nonsense 645 704 17 18
ENSDART00000134592 Nonsense 677 736 17 18
Genomic Location (Zv9):
Chromosome 21 (position 21372538)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22384031
GRCz11 21 22420667
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATGTGAAAGCACCCTAAGTGATTTTTTTTTTCCCCACAGAGGCAAAGTA[C/A]ACACGAAGTGGCAGCCAATCAGGACGAGACAGCATTGAGTTGTTACAAGA
Long Flanking Sequence:
TTGTTGCAAATAATTTATATATGTTGAGTTTAAACAAATTAAAGTTAGTAATGTTCGATTTATTTGTTTGTTTAAATTCAGCCCAAATAAATTGTTTACAACCACTTAACTTAAATAAATGTAGAAAATCCAAGGACTCATCTTTGTTACATTTTTTTCACTGCATTTAAATGACTTGCTTTTCTGACAAGCGTAACTGACGTGCTGCAAGCAGAAAGAATGTTTTATTGTTTGATCTGGTTTTTGCTCAACTTCAGCAGAAAACAACTCTCTTCTCATTTATTTGTACTTTTACGTGACAGTCATGATAAATAGACGCATGTGTTGCTCAGTGTTAGCACCGTGAAAATGAAACTACATTTTTAAAGTCCAAAGTTCAAACTAGAGACACGCAAGATGTGGTATACAGCAGTTTTGCAGCTTCTCCTGTGCCACACTTACCTAACAACAAATGTGAAAGCACCCTAAGTGATTTTTTTTTTCCCCACAGAGGCAAAGTA[C/A]ACACGAAGTGGCAGCCAATCAGGACGAGACAGCATTGAGTTGTTACAAGATGCCGAGCCACTGGATTTTAATGCTGAAACACTCACTGATGACCCATTGCAGTCCGACACTGGCAGGTCAGATTGAGTACATTAAAGCTCTGCAATCATCACGTATTTATTTTCTAAGGTCAACCCATAAGTTTGTATCACATTTAATTCCTCTATAAAATCCCAACAGGATTTTTTAAAGATTAAATAAAAAATTCAAAGGTTTGCAGTTTCTGCCTCAAAAATGCTGTTTTTGTGTAAACGAAGAGTCAAATGCGATAAGGATTTTCCATTTTTAGTTGAAAGTGGAAGTTAAAAATGCAAAGCTATTTCCAGGTATTACTCTTCAAAAAAAAAAGTGATCCCTGCAGCACTCTAGTCATAAGGTTTATTTGTGTACACGCATTTGATTTGTGCTCTTTTTATTTCTTTTCCCACAGACATGCTGGTGGAAGGTACCTCTCGATGTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23925
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021682 Nonsense 647 704 17 18
ENSDART00000134592 Nonsense 679 736 17 18
Genomic Location (Zv9):
Chromosome 21 (position 21372542)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22384035
GRCz11 21 22420671
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAAAGCACCCTAAGTGATTTTTTTTTTCCCCACAGAGGCAAAGTACACA[C/T]GAAGTGGCAGCCAATCAGGACGAGACAGCATTGAGTTGTTACAAGATGCC
Long Flanking Sequence:
TGCAAATAATTTATATATGTTGAGTTTAAACAAATTAAAGTTAGTAATGTTCGATTTATTTGTTTGTTTAAATTCAGCCCAAATAAATTGTTTACAACCACTTAACTTAAATAAATGTAGAAAATCCAAGGACTCATCTTTGTTACATTTTTTTCACTGCATTTAAATGACTTGCTTTTCTGACAAGCGTAACTGACGTGCTGCAAGCAGAAAGAATGTTTTATTGTTTGATCTGGTTTTTGCTCAACTTCAGCAGAAAACAACTCTCTTCTCATTTATTTGTACTTTTACGTGACAGTCATGATAAATAGACGCATGTGTTGCTCAGTGTTAGCACCGTGAAAATGAAACTACATTTTTAAAGTCCAAAGTTCAAACTAGAGACACGCAAGATGTGGTATACAGCAGTTTTGCAGCTTCTCCTGTGCCACACTTACCTAACAACAAATGTGAAAGCACCCTAAGTGATTTTTTTTTTCCCCACAGAGGCAAAGTACACA[C/T]GAAGTGGCAGCCAATCAGGACGAGACAGCATTGAGTTGTTACAAGATGCCGAGCCACTGGATTTTAATGCTGAAACACTCACTGATGACCCATTGCAGTCCGACACTGGCAGGTCAGATTGAGTACATTAAAGCTCTGCAATCATCACGTATTTATTTTCTAAGGTCAACCCATAAGTTTGTATCACATTTAATTCCTCTATAAAATCCCAACAGGATTTTTTAAAGATTAAATAAAAAATTCAAAGGTTTGCAGTTTCTGCCTCAAAAATGCTGTTTTTGTGTAAACGAAGAGTCAAATGCGATAAGGATTTTCCATTTTTAGTTGAAAGTGGAAGTTAAAAATGCAAAGCTATTTCCAGGTATTACTCTTCAAAAAAAAAAGTGATCCCTGCAGCACTCTAGTCATAAGGTTTATTTGTGTACACGCATTTGATTTGTGCTCTTTTTATTTCTTTTCCCACAGACATGCTGGTGGAAGGTACCTCTCGATGTCATCTT
Associated Phenotype:
Not determined