ZMP
bcl11a
Ensembl ID:
ZFIN ID:
Description:
B-cell lymphoma/leukemia 11A [Source:RefSeq peptide;Acc:NP_001035481]
Human Orthologue:
BCL11A
Human Description:
B-cell CLL/lymphoma 11A (zinc finger protein) [Source:HGNC Symbol;Acc:13221]
Mouse Orthologue:
Bcl11a
Mouse Description:
B-cell CLL/lymphoma 11A (zinc finger protein) Gene [Source:MGI Symbol;Acc:MGI:106190]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa18 | Essential Splice Site | Confirmed mutation in F2 line | Not yet available |
| sa22311 | Nonsense | Available for shipment | Available now |
| sa38944 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa18
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000087426 | Essential Splice Site | 19 | 829 | 2 | 3 |
| ENSDART00000132521 | Essential Splice Site | None | 68 | 2 | 2 |
Genomic Location (Zv9):
Chromosome 13 (position 26080506)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25726166 |
| GRCz11 | 13 | 25856616 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCTGCTTTTCATTCCCTCTGTGTCGCATATGGATTCTTCCTGCGTGCA[G/A]CCGAGCCCCTGTCAGCCGTGGTCTCGGAGGAGAGGCAGGAACAGCGCGGG
Long Flanking Sequence:
AGTACTTTTACTCCAAGTGTGAAGCATGTATTGATGCTGCTGTGACTGTTTTGGTTTTGCTGGATATCTACACGTGTTGTACATGCAGTCATAATCCAGATGTGTGTGTGTGTGTGTGTGTGTGGTTGAGTGAAACAGTCAGTCTGAGATGTAGTTTTAAAAACCAAAACAGATATAACTTATGTTCATTTTAGTGTTATATTATCATGAATCAAGATGTCATGAACTTTTAAGGATTCATATTTTTATGATTGTGAAGTTTTGTTTTTACAAAATGTTTATTTTGTAAATTATTTTATGCTTAAATTATTATTATTATTTTTTTTTTACAATTTCTGAGGTAATCACCTTTATGATTCTGAAATTAAAAACTGAAGTTTGATTTGTAAAATATTTTTTGTGCTCCCTCATCTTGTCTGCGTTCATTACTACACCCAGTCTCTAATATTCTCTCTGCTTTTCATTCCCTCTGTGTCGCATATGGATTCTTCCTGCGTGCA[G/A]CCGAGCCCCTGTCAGCCGTGGTCTCGGAGGAGAGGCAGGAACAGCGCGGGCTGGTACAGGTAGCTCCAGAGGGAGACCAGGACCTGCTCACCTGTGGCCAGTGTCAGATGAACTTCCCTTTGGGAGACATCCTTATTTTCATTGAGCACAAAAGGAAGCAGTGCAATGGCACTTTGTGCATGGACAAAGCAGTGGATAAGCCCCCCTCGCCCTCGCACGGTGAGCTGAGGAGAGCCTCCAACCCGGTGGAAGTGGGCGTCCAGGTCACGCCGGAGGACGATGACTGCTTATCGACGTCTTCTCGAGGAATCTGTCCCAAACAGGAAAACATTACAGGTAACCTCACCCAACGTGATTTCTCTTTCATATTATAGCCTGTGTGTATCTGTTTGTGGTGAAGCAGAGTTGTTGTGTGGGCCACATATCGTAGACACATGTCCTTTCTCCATGGGGCGTCTTGGAGACGTATGAAGAGTGCTGAATATTTAAGAGCTGTGGCA
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |
Mutation Details
Allele Name:
sa22311
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000087426 | Nonsense | 371 | 829 | 3 | 3 |
| ENSDART00000132521 | None | None | 68 | None | 2 |
Genomic Location (Zv9):
Chromosome 13 (position 26147395)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25793055 |
| GRCz11 | 13 | 25923505 |
KASP Assay ID:
2260-6466.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACCAAGTCTTGTGAATTCTGTGGGAAGACCTTCAAGTTCCAGAGTAATT[T/A]AATAGTGCATCGACGCAGTCACACGGGTGAGAAACCATACAAGTGCCATC
Long Flanking Sequence:
CCCGTTCAACCTTCTACGAATACCGAACTCTGGACGAGATGGGCCCCCTCTCCGAGAAGGGCGGTTTCCTCCTACGCCGCCTCTTTTTAGCCCTCCACCTCGTCACCACTTGGACCCTCATCGCATGGAGCACCTGAGCCCGGAGGAGCTGGCTTTGGCCACCCACCACCCGAGTGCCTTCGACAGGGTGCTACGCCTCAACCCCATACCCATGGATCCCCCAGCTATGGACTTCTCTCGTAGGTTGAGAGAGCTTGCTGGTAACACCTCAGGGTCAACTCCTCCTCTTTCACCTAATCGGCCCAGCCCTATGCAACGGCTACTACAACCATTCCAGTCAGGAACCAAGCCGCCCTTTCTCTCCACCCCTCCCCTACCTTCCATGCAATCTCCCTCTGGCTCCCAGTCTACCCCGACCCCTCTCAACCAACAGTCCAACACGCCCATGAAGACCAAGTCTTGTGAATTCTGTGGGAAGACCTTCAAGTTCCAGAGTAATT[T/A]AATAGTGCATCGACGCAGTCACACGGGTGAGAAACCATACAAGTGCCATCTGTGCGACCATGCCTGTACACAGGCCAGCAAGTTGAAAAGGCACATGAAGACGCACATGAACAAGTCATCGCCCACAACGGTCAAATCCGATGATGGCTTGTCCACAGCTAGCTCCCCTGAACCAGGAACCAGCGACTTGGTGGGTAGTGCCAGTAATGCCCTCAAGTCTGTGGTAGCCAAATTCAAGAGTGAAAATGACCGCATGATTCCAGAAAATGGAGAGGAGGAGGAGGAAGAGGAAGAAGAGGAGGAGGAGGAAGAAGAAGAGGAAGAGGAAGAAGAGGAAGGAGAAGAGGAGGAACTGGAAAGGGAAAGGGAGAGAGAGAGGGAGAGGGAAAGGGAGAGGGACAGAGATGGAGGGAGAAACAACTACCACTTCAGTCTCAACCTTCAAGCTGCACGACACCACGAGAACAATGGTGGGCGTCTGGGTGAGGATGGGATCCCGC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38944
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000087426 | Nonsense | 676 | 829 | 3 | 3 |
| ENSDART00000132521 | None | None | 68 | None | 2 |
Genomic Location (Zv9):
Chromosome 13 (position 26148309)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 13 | 25793969 |
| GRCz11 | 13 | 25924419 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGCTGCTTCTAGGCAGCTCAAGGACCCCTTTCTGAATTTTGGGGATTCC[A/T]GACAATCGCCTTTCGCCTCATCTTCAGAGCACTCCTCAGAGAATGGAAGC
Long Flanking Sequence:
GAAACAACTACCACTTCAGTCTCAACCTTCAAGCTGCACGACACCACGAGAACAATGGTGGGCGTCTGGGTGAGGATGGGATCCCGCGCTCACTGCCTGAGGTTATGCAGGGCATGGGCCTGGCTGCCAGCATGCAGCACTACAGTGAGGCATTTCACCAACACAAGCGGGGAGCTCTAAACTCCGACAATGATGCACATAGGGACATGTGTGATGAGGATTCGGCTCTAGAATCAGACAGAGTGGACGAGGGTTGCGGTTCAGCTATCAACGGCCGCGGCTCTTCTCCAAGCGAATCTGCCTCTGTAGGCTTGTCCAAGAAGCTCCTGCTTGGTAGTCCCAGTTCACTTAGCCCTTTCTCCAAACGAATCAAGCTGGAGAAGGACTTTGACCTCTCCACCCCTACAATCCCCAACACTGAGAATGTTTATTCCCAGTGGTTGGCTGGTTATGCTGCTTCTAGGCAGCTCAAGGACCCCTTTCTGAATTTTGGGGATTCC[A/T]GACAATCGCCTTTCGCCTCATCTTCAGAGCACTCCTCAGAGAATGGAAGCCTGCGCTTCTCTACGCCACCAGGGGACCTAGACGGCGGGGTCTCGGGCCGCAGCGGGACTGGCAGTGGCGGCAGCACGCCACATCTCGGGGGTCCTGGTCGGCCCAGCTCAAAAGATGGGCGACGTACTGACACCTGCGAGTTCTGTGGCAAAGTATTCAAAAACTGCAGCAATCTGACAGTGCACCGGCGCAGCCACACGGGCGAAAGGCCTTATAAGTGTGAGCTCTGCAATTACGCCTGCGCCCAGAGCAGCAAGCTAACACGGCACATGAAAACGCACGGGCAAGTGGGCAAGGACGTTTACAAATGTGAAATCTGTCAGATGCCTTTTAGTGTGTACAGCACCCTTGAGAAACACATGAAAAAATGGCACAGTGACCGCCCATTGAGCACCGAAATTAAAACTGAGTAGCGGTGGAGTGTGGTGGCTCACTTGCCTATTAACAGC
Associated Phenotype:
Not determined