Busch Lab

ZMP

mcm3ap

Ensembl ID:
ENSDARG00000021402
ZFIN ID:
ZDB-GENE-040715-1
Description:
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein [Source:UniProtKB/TrE
Human Orthologue:
MCM3AP
Human Description:
minichromosome maintenance complex component 3 associated protein [Source:HGNC Symbol;Acc:6946]
Mouse Orthologue:
Mcm3ap
Mouse Description:
minichromosome maintenance deficient 3 (S. cerevisiae) associated protein Gene [Source:MGI Symbol;Ac

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa41485 Nonsense Mutation detected in F1 DNA Not yet available
sa41486 Nonsense Mutation detected in F1 DNA Not yet available
sa8980 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13572 Nonsense Available for shipment Available now
sa34707 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa17895 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa41485
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008053 Nonsense 71 2118 1 30
ENSDART00000056051 Nonsense 71 1820 2 26
ENSDART00000142512 Nonsense 71 2082 2 31

The following transcripts of ENSDARG00000021402 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 39510791)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38648687
GRCz11 9 38458482
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACACCACAGCCTCCAGTCTTCACACCCACTTTTGGCCAAACCGGCGGGT[T/A]ATCTCAAGGATCGGGGCAAACATCATCATTTTCCTTTTTGGGAACACACC
Long Flanking Sequence:
ATATAGACTTGAAACACATACACATATTATAGGTTTTTAGGTAGTTCGTTTTGGAGTTAAACAAGTAATCGGCATTCAGCTCTCAGATCGCCATTTGTTTTTAACGATGTCCCACTTGAGCTTTTAACTTTACATTTAATAACTTCTGTCATGTGACTTCTAATAGATAAAATGGTAAAACATTGGTAACTTTTCTGTCTTTGTTTTGCAGGATTCGTTGGTAATGACTAGCTCACGATCAGATCAGTAACGTTAAATCTTAACGATTGTTTTTCTTGCCTCATCCATTATGAATCCTTCAAACATCTTTGGCAGACCACAAGCTGCCTTTCAGGCACCGAACACTAATCAGTCTGGAAACCTATTTCAGACTTTTGCCCAGCAGAAACCAACACAGGGTGTTAGTTTTGGCCAACCTTCTGCTTTTAGTCAGCCAGCTTTTGTTCAGCCAACACCACAGCCTCCAGTCTTCACACCCACTTTTGGCCAAACCGGCGGGT[T/A]ATCTCAAGGATCGGGGCAAACATCATCATTTTCCTTTTTGGGAACACACCCTGCCTTTGGGCAGCCAAGTTTAGGTCAGGGGGGCACACTTGGATTTGGACAACCACCACCACCTTCATACTCTCAAGCTACGGGACAGACTCAGAACTCAGCTTTCGGTCAGCCGTCTGCATTCAGCCTTCCCTCCTATGTCTCGCAGTCCTCCTCAACCAGCTTCAGTAGCACTGTTACTAGTCAGCCTAGTTTTGGTCAGCTCTCTGGTCTTCCTGTACCAGCAGCAACATCCATCTCCTCAATAAGCGGCAGGGCTGAGAATCCCACAGGTGGGAATCAGTTTTCTTTCAAACCACCAAATGAAGCAGTCTTCAAGCCTATTTTTAGTGTCAGTCCGGAACCAACAAGCACGAATATGTCTTCTGCTTCAGAAACTGCTGGATCCTCTAAGGTGGTGGATAATTCCTCTGGTGGTTCACTGTTTTCATGCGTAAAACCAAGCGCTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41486
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008053 Nonsense 105 2118 1 30
ENSDART00000056051 Nonsense 105 1820 2 26
ENSDART00000142512 Nonsense 105 2082 2 31

The following transcripts of ENSDARG00000021402 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 39510892)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38648788
GRCz11 9 38458583
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGCCTTTGGGCAGCCAAGTTTAGGTCAGGGGGGCACACTTGGATTTGGA[C/T]AACCACCACCACCTTCATACTCTCAAGCTACGGGACAGACTCAGAACTCA
Long Flanking Sequence:
TAACGATGTCCCACTTGAGCTTTTAACTTTACATTTAATAACTTCTGTCATGTGACTTCTAATAGATAAAATGGTAAAACATTGGTAACTTTTCTGTCTTTGTTTTGCAGGATTCGTTGGTAATGACTAGCTCACGATCAGATCAGTAACGTTAAATCTTAACGATTGTTTTTCTTGCCTCATCCATTATGAATCCTTCAAACATCTTTGGCAGACCACAAGCTGCCTTTCAGGCACCGAACACTAATCAGTCTGGAAACCTATTTCAGACTTTTGCCCAGCAGAAACCAACACAGGGTGTTAGTTTTGGCCAACCTTCTGCTTTTAGTCAGCCAGCTTTTGTTCAGCCAACACCACAGCCTCCAGTCTTCACACCCACTTTTGGCCAAACCGGCGGGTTATCTCAAGGATCGGGGCAAACATCATCATTTTCCTTTTTGGGAACACACCCTGCCTTTGGGCAGCCAAGTTTAGGTCAGGGGGGCACACTTGGATTTGGA[C/T]AACCACCACCACCTTCATACTCTCAAGCTACGGGACAGACTCAGAACTCAGCTTTCGGTCAGCCGTCTGCATTCAGCCTTCCCTCCTATGTCTCGCAGTCCTCCTCAACCAGCTTCAGTAGCACTGTTACTAGTCAGCCTAGTTTTGGTCAGCTCTCTGGTCTTCCTGTACCAGCAGCAACATCCATCTCCTCAATAAGCGGCAGGGCTGAGAATCCCACAGGTGGGAATCAGTTTTCTTTCAAACCACCAAATGAAGCAGTCTTCAAGCCTATTTTTAGTGTCAGTCCGGAACCAACAAGCACGAATATGTCTTCTGCTTCAGAAACTGCTGGATCCTCTAAGGTGGTGGATAATTCCTCTGGTGGTTCACTGTTTTCATGCGTAAAACCAAGCGCTCTGGGCTTCAGCTTCTCTCAGCCGGCTGCAGCTCCTTCTGTTTCTCTCTCTAATTCTAATTTTTCACAAAAGGAGACAGTTGGTGGTGGCGGCAGTAGCATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8980
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008053 Essential Splice Site 718 2118 6 30
ENSDART00000056051 Essential Splice Site 718 1820 7 26
ENSDART00000142512 Essential Splice Site 718 2082 7 31

The following transcripts of ENSDARG00000021402 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 39516735)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38654631
GRCz11 9 38464426
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACACGCAACCAACTGAGTGTCTTTGAGGTSGTTCCAGATACTGAAAAGG[T/A]TTGTGATAATATGCAGTGTCTAATAATGSCTATGTTCACNTTTTTTYTGC
Long Flanking Sequence:
AAAGAAATCCTCTATTGCTAAAACTCTCCAGTTTGAAAGTGAGGGACCGTTTGAGTCTGTCTCAGAGGAGCGAAGCATAGAACGGCCCATAAATATCTTGCCCTCAGTTCTGCAGCCTCTGGTTGGTCAGGTGGCTGAATGTGCAGAGGAGAGGTATCGCCTCCTAGAACAGAGAGATAAAATCTTACGTCAAGGTAAAGCCTAAAGTTGCTTTGATGCTTAATTTTATTACAGTAACTTTAATATAAAATTGTATCTCAAAAATAATTATTAACTGTTACTCCGAATAGTAAGATGGTGTTTGTTTTATTTGTTGTAATAGTGTACACATTTATAATAATAAGCTTTTGTCTCTGAAGCTCGACCCAAAAGAACAGACCTGGATATGTCTAAAGTATTTGTGGGAACATGCCCTGATATGTGCCCTGAGAAGGAACGGTATATGAGAGAAACACGCAACCAACTGAGTGTCTTTGAGGTCGTTCCAGATACTGAAAAGG[T/A]TTGTGATAATATGCAGTGTCTAATAATGCCTATGTTCACATTTTTTCTGCCGTTTTTATCTAAAATTAAGATTTAATGTCAGAGTTTGGTCATATTGTAGGTAGTAGGTAATATTACTTAGTGTTAGCTTATCCAAAAATGAAAATTACTCGCCCTCATGTCACTTCAACCCCCTGAGAACTTTATTCGTATTCAGAAAACAAATTAAAATATTTTAGATGTGTTCCAAGAGCTTTTGTCCACATTCTTCATAGATCGCATGGTTAACGTCTGAGTCAAAGTTCAGAAAAGAAACTGAAAATCATCCTCAAAACAGTTCATGTGTCTTCAGTGATACAATCAGAATATTTTCAAGCTACAAGAATACTTATGTGCGCATAATAAAGAAAAATAACTTTATTTAACAGTTTCTTCTTACAGTCAGTATACGGTGGATGTTTATGTTTCTCATATTACCTCAGATGTGCATGTGCTTAGTTTTAAACAGAGAATAAACTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13572
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008053 Nonsense 722 2118 7 30
ENSDART00000056051 Nonsense 722 1820 8 26
ENSDART00000142512 Nonsense 722 2082 8 31

The following transcripts of ENSDARG00000021402 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 39517611)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38655507
GRCz11 9 38465302
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGACTTTTGAGTGGATTACATTATCACCTTCTGCTTAGGTGGATCATTA[T/A]GCTGCTAKCAAAGAGTATAGCAGGTCTTCAGCTGATCAGGAAGAACCTTT
Long Flanking Sequence:
GCATAATAAAGAAAAATAACTTTATTTAACAGTTTCTTCTTACAGTCAGTATACGGTGGATGTTTATGTTTCTCATATTACCTCAGATGTGCATGTGCTTAGTTTTAAACAGAGAATAAACTGTTGAATAAAGTAGTTATTTTTGTTTATGTGCACACAAAAGTATTACTGCTCTAGGCATATGGTATGTTTTGAGGGTGTTTTTGGTAACCTTCTGCACTTTAAACCAGTTAGGAACCTACATATGTATATGGAGGATGAGGGAGCTCTCACCTAAAGTAGCTTAATTTGTATTCTAAAGATGAACAAAGCTCTCAGCGATTTGGAATGACATGAGGGTGAGTAATTAATAACAAAATTATAATCAATTTGGTTATTACTACCTTTAAATGCTTGGATACCTTCAAAGATTTGTGTAGTCATTTGTGTGACAAACTTTGTGTGTCTTTGGTGACTTTTGAGTGGATTACATTATCACCTTCTGCTTAGGTGGATCATTA[T/A]GCTGCTATCAAAGAGTATAGCAGGTCTTCAGCTGATCAGGAAGAACCTTTACCTCATGAGCTTAGACCCCTTCCTGTGCTAAGCATGACTATGGACTACCTGGTGACTCAGATTATGGACCAGGGTGAAGGCAATTGCCGTGACTGGTATGACTTTGTCTGGAACAGAACCAGAGGCATTAGGAAGGTGGGCATTTAATTGCTTTTAATTGCTTCATTTACTATTGATTTGATTGTATTATTCATTTAAATATAAAAACTAATTGATTTAATATAAACTTCTTCTCTGTATTAAGTTTGTTACAATTTCTTCTTTTCTTGCAGGACATTACCCAGCAGCATCTGTGCGATCCAGAAACAGTATCTCTCATTGAGAAATGTACTCGTTTCCACATTCACTGCGCCCATCACCTCTGTCAGGAACCTATGATGTCTTTCGATGCCAAGATCAACAATGAGAATATGACAAAATGCCTGCAGAGTCTAAAGGAGATGTATCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34707
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008053 Essential Splice Site 1177 2118 13 30
ENSDART00000056051 Essential Splice Site 1141 1820 14 26
ENSDART00000142512 Essential Splice Site 1141 2082 14 31

The following transcripts of ENSDARG00000021402 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 39523036)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38660932
GRCz11 9 38470727
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCTCTGATGTAACGCGTTCAGCTGCTGAATATGTGTCCGCAGCCCTCAG[G/A]TAGGATGCTTTTCCTGTCACTTTAGGGTTAAAATTATTGAAGGTTAAAAT
Long Flanking Sequence:
AATGTATTACAGGAAATATCAGAATATTTGTGCTTACAAGTTCCTTTGTTCTTGGCAGCTCCTGCAGAAAGGCAGATTTTCATGGAGCCTGAACCCAGGCCTCAGGTGAAAACAAGGCTTTTAGCCGAACCACGGCTTTTCATGGGTCTCTCTGAGCCTGTAAAAGCTGATGACACAGAAGAAACAGGAGAGAAGTCTCAAACAGCAGAGTCAACTCTTCCTGTAGTGCAACAGCCTATTTTTCCACCCATACTAGCACCACAGCCGGTTCGACCCCCATCTCCTCCACCCAAACCAGAGCCAACCTACACGGATCAGGTGAGAGGCTTTTCAGTCTTAAGCACAAAATGAAGCAATCCTTCCCATAAATAAGCTCACCCATGACATCATCTATTGCAGGATATTATGGCAGAAGTGGATGCAGTGGTTAATGAGGTGTTGGAGGCTGAAGTCTCTGATGTAACGCGTTCAGCTGCTGAATATGTGTCCGCAGCCCTCAG[G/A]TAGGATGCTTTTCCTGTCACTTTAGGGTTAAAATTATTGAAGGTTAAAATCTAGCAAGTAGTATGATCATGCATTTCTTTAAAAAAAAAAAAAAAAAAAAAGCTTTATTAAAAACTTTATTGGGGCAATTCATTCTGACATAGTATGGTGCTTCACATATAAAATAAATGACACTTTACTCAATAAATTTCAACACTTAACATGAATAATAATTATAATAATAAACCATCAATCAACTACATTTATCTTGTAACCGAATTGTTTCAGGCACAAAAGTAAATATATAACAATTCGTGGAACATCTAATTGTCTTTAGATGTCCACCCAAGGGGCATCCAATCAAAATAATAGTTTAAGGGGTATGTGCAAACTCCTGTTATTTTATGTGCCATCCTCAACACCTGCTGTTCGTCAAAAGACTTTCCAGGGAAACTCCCAGAATTTTTAAGCACATATTTTGTTTTACTCCTTTAAACCAAGCATAATAGATCTCTATCATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17895
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008053 Essential Splice Site 1492 2118 20 30
ENSDART00000056051 Essential Splice Site 1456 1820 21 26
ENSDART00000142512 Essential Splice Site 1456 2082 21 31

The following transcripts of ENSDARG00000021402 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 39525917)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 38663813
GRCz11 9 38473608
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCTGACCAATATTAGGGGACAGACTCATGAAGTTTACATTTCTGTAAAGG[T/C]RAGCTTATAGWGTAAATANTTTGAAMAAATTTGATTATTATTTACTYCAT
Long Flanking Sequence:
CAGTTCATCAAATGAAAGTGTCCTATTACTACAATCTCTTAATGAGGTGAGGCACAGTGACAAGACGACTTGGAATAGATGTGCAGAATGCCGATAATTTATTTTTAATCTATGTGGCTGAATAATTGTTTGGCAGTGAGCGTGTATGGATGCCTCTTGACCTGCCCACACTTGTGGCAGAGAGCACTCCTAATGCACCTGACAGAATCTTCTGGAAAGCTACGCTTCTGATGCCAAGCAGCTGCGATAGTGACATAACCTTTGCCAGCAGGTGAGTATTGAAAAGATCGTAAAGTTTTTTAAAACACACAAGATAAAAACTGACTTGTGTTTGTTTCCATGCAGAATTCTGACAGATTGGCTTGAGGTTAAATTGGGTGGAGGAAATGAATCTGAAGAGAGTGAGAAACAATCAAAAGGGCAAGTGAAAACGCTGTGTGTCAGTCACAGCCTGACCAATATTAGGGGACAGACTCATGAAGTTTACATTTCTGTAAAGG[T/C]GAGCTTATAGAGTAAATAGTTTGAACAAATTTGATTATTATTTACTTCATTACATCAGTCCTACGCCTCAGTCACTTCAATATCACCATCATTAAGCTTGTGTGTGTGCATTTGCACAGGCATGCCATGGACCTTTGAGTGCAGAAGACCAGTGTCTGCTGGAGGAGCAGAAGGAGCTCCATGGTACCAATGCTCTGCTGATGCTGCTTCCCCCTGTTAACAGTGCTGGACAGGGGGAAGAAGAAGAAGAAGAAGAAGAGGAGGAGGACCTGCCACTGCTCTCTGCCCTCCTCCAGCTGAGGCAGGTACAGCAGGCCAGCTGCTGGCATTCTCCTCTACCACTGGCTGTGGTGGTCGCTGGCAACCAAATTGGTGATCAGGGTTTGGAACAAGGCAAGTAATAATCGAAAAGTTGGAAACACTTTATAATATCTACACACTATGAATCATTTGTTAAGCATTAGCAAATAGTTAATTCATTATCTGTTTAGCATTAACTC
Associated Phenotype:
Not determined