Busch Lab

ZMP

ric8b

Ensembl ID:
ENSDARG00000005972
ZFIN IDs:
ZDB-GENE-030131-6435, ZDB-GENE-030131-6435
Description:
Synembryn-B [Source:UniProtKB/Swiss-Prot;Acc:Q6DRJ9]
Human Orthologue:
RIC8B
Human Description:
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) [Source:HGNC Symbol;Acc:25555]
Mouse Orthologue:
Ric8b
Mouse Description:
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) Gene [Source:MGI Symbol;Acc:MGI:

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa36603 Nonsense Mutation detected in F1 DNA Not yet available
sa1716 Nonsense Confirmed mutation in F2 line Not yet available
sa36602 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13369 Essential Splice Site Available for shipment Available now
sa17855 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa36603
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019818 Nonsense 139 536 3 10
ENSDART00000091428 Nonsense 139 282 3 5
Genomic Location (Zv9):
Chromosome 18 (position 14907152)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15352570
GRCz11 18 15321082
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGCCCTTAAGTGCCTGTGCAACGTAGTGTTCAATAGCGTGCCGGCACAG[C/T]AGATGGGAGGTGACTTGCAGTTAGCGGAAGGCCTATGCCCCCGCTTGCAT
Long Flanking Sequence:
AGTTTGATCAGGGGTGTTTAATTAGGGTTGGGACTAAGCTGTGCAGAGCTGCAGCTCTTCAGGAACTGGACAGCTGTGCTCTATACGATGATCTGTTGGTGCCAAATCAATCATTTTCCTTTGTTGTTGTTGACATTAAGGTTATTATTTCATAAACATATTTCCATTCTAAGTTATTCACATTTTAATGCACTTCGTCTTTCTTGTCTTGTTTGCAGAAATTATGTCAGGGTCTTCTTACAGTCCTCCGTCGGTCAGATCTTCCACTTTGCCAAAGCACCTGCCTGGAGACCCTGCGCATCTTGTCCAGAGACAAGCATGTGCTTGGACCCGTAGCCACCAAAGAAGGAATGCTTACTTTAGCAGGACTTGCCCGGATCTGTGTGGCGGGCCATGAAGGCGAGCCATTAGAGGAGGCGCAGTCAGCAGAAGAGGAGAGGGTTGTGGTGGAGGCCCTTAAGTGCCTGTGCAACGTAGTGTTCAATAGCGTGCCGGCACAG[C/T]AGATGGGAGGTGACTTGCAGTTAGCGGAAGGCCTATGCCCCCGCTTGCATTTGGTCAGCGCGTCACATCATGAAGTGGGCTTATTTTCCCTCCGGCTGCTGTTTTTGCTTTCGGCTCTGCGGACGGATGTGCGCTCCACGCTTCAGAAGGAGGCAGGCGCGGTGAAACTACTCACTAATGTGTTGGAACGCACTCTTGATGTGCGTTGGGTTGGGCCATATGAGGCTGCACCTCCTGATCCAGAAGCTCCACCCATTCCACCAGAAAACAACGAGCTTACCATGGAAGCCCTCAAAGCCCTGTTCAACCTCACCATGTCTGATTCCTGTGATAAGGTGAGAGTGTCAGTATGTGTAGAACAGCAATATAATCTAGTATCTATTCTGTGGTGTCGAACTTGCTATATTATTCAACTCCAAATTGTACTATTTTATGCATAAGTTAGCATGCACACATTGTTGAATGCACCTTCAAAACACTTTCAAAGTATATTATATTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1716
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019818 Nonsense 200 536 3 10
ENSDART00000091428 Nonsense 200 282 3 5
Genomic Location (Zv9):
Chromosome 18 (position 14906968)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15352386
GRCz11 18 15320898
KASP Assay ID:
554-1662.1 (used for ordering genotyping assays)
KASP Sequence:
CTCCACGCTTCAGAAGGAGGCAGGCGCGGTGAAACTACTCACTAATGTGT[T/A]GGAACGCACTCTTGATGTGCGTTGGGTTGGGCCATATGAGGCTGCACCTC
Long Flanking Sequence:
TTAATGCACTTCGTCTTTCTTGTCTTGTTTGCAGAAATTATGTCAGGGTCTTCTTACAGTCCTCCGTCGGTCAGATCTTCCACTTTGCCAAAGCACCTGCCTGGAGACCCTGCGCATCTTGTCCAGAGACAAGCATGTGCTTGGACCCGTAGCCACCAAAGAAGGAATGCTTACTTTAGCAGGACTTGCCCGGATCTGTGTGGCGGGCCATGAAGGCGAGCCATTAGAGGAGGCGCAGTCAGCAGAAGAGGAGAGGGTTGTGGTGGAGGCCCTTAAGTGCCTGTGCAACGTAGTGTTCAATAGCGTGCCGGCACAGCAGATGGGAGGTGACTTGCAGTTAGCGGAAGGCCTATGCCCCCGCTTGCATTTGGTCAGCGCGTCACATCATGAAGTGGGCTTATTTTCCCTCCGGCTGCTGTTTTTGCTTTCGGCTCTGCGGACGGATGTGCGCTCCACGCTTCAGAAGGAGGCAGGCGCGGTGAAACTACTCACTAATGTGT[T/A]GGAACGCACTCTTGATGTGCGTTGGGTTGGGCCATATGAGGCTGCACCTCCTGATCCAGAAGCTCCACCCATTCCACCAGAAAACAACGAGCTTACCATGGAAGCCCTCAAAGCCCTGTTCAACCTCACCATGTCTGATTCCTGTGATAAGGTGAGAGTGTCAGTATGTGTAGAACAGCAATATAATCTAGTATCTATTCTGTGGTGTCGAACTTGCTATATTATTCAACTCCAAATTGTACTATTTTATGCATAAGTTAGCATGCACACATTGTTGAATGCACCTTCAAAACACTTTCAAAGTATATTATATTTTACAGCGTGCATGCTCAATAGAGCTGTGGCAAAAAATAGTTTGAGAAATTGATTCTGCATAGATTCTGAGATTTTCAAAATGCATCGCTATTCTTTTTTGAATCCACTCTTAGCCTAGTTTTTAACAGCAGATAGATTTTAACTGTGTACTTAAAGTGGAAGGCCATTACTTTTAATTTATCTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36602
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019818 Essential Splice Site 282 536 4 10
ENSDART00000091428 Essential Splice Site 282 282 4 5
Genomic Location (Zv9):
Chromosome 18 (position 14904589)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15350007
GRCz11 18 15318519
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCTAATGCTGAAAACACACACTGAAGAAAAAACTGAGGAGACTCACAGG[T/C]ACTTCCAAACTAGGGCTGCACGTTATTGGAAAAATCTGATATTGCCATCC
Long Flanking Sequence:
GGCTCAAAGCTGTCAGGTTGTTATTTGTAAATCAAGTTCTAAACTCTGTATCAGAGTATTTCTATCAAATTTCAAATAAATTTTACTGCTTACTTTCTGATAGTTCTTTTGAAGTTAGCATATCTATTTCTAGCAAAATATCAAAACATATTATTATTATTACTAGTAAGAGTTTTTAAACAAAATAAATCCGTCTTCTGTACCTTTTATTTTCATACAAATAATATTCTTTATTTATTTTCAGAGTTATTTATTTACATTACTATAACTTTAGATTAAAAAAAATGCTTTTGGCAAAATTTTCTTTAAAGCTCAAAATTGTTTTGGTATTTTCCTTTTTAAAAGCTGCCCCAAATGCACTGTGAAAATGAACACTGACATCATTTTCCCTTTTATTTGAATAGGACAGTCTCCACAAACTTCGGCTGATTGCAGGCATCATGAGACACCTCCTAATGCTGAAAACACACACTGAAGAAAAAACTGAGGAGACTCACAGG[T/C]ACTTCCAAACTAGGGCTGCACGTTATTGGAAAAATCTGATATTGCCATCCCCCCCCCCCCCCCCCCAAAAGATGGTTTGAATAGCACTATTTGATGTTCTCTGGGGGGCTAACAGTATTCAGTATTGAATAATCACAGTATTGAATAATCACCATGCAAAAAAAATGCTTTTCTTGCTTTTTTATTGTCTATTTTTTCTAGTCCAAGTATTCAAAAATTCTTAAACCAAGTAAAAATATTGTTTTAGTTTTCACCGTCAGTAGAAGTAAGTGAAAATTAAGAGTTTTTTTGCTTGTTTTAAGGAAATGATCAGCCAGTGAGGTAAGTGAAATAGTCTTGTTTTAACTTTGAAATGTAGATATTTGGACTAGAAACAAGACAAAAATTCTAAATAAAAAATGTTTTTTTTGCATAACTTGTGTAAATTCCATGCAAATGCAGTGATTAAATACAGTTCTGTAGTTCCTGGTCAACTATAATTCATACTGGACATTACATGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13369
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019818 Essential Splice Site 413 536 7 10
ENSDART00000091428 None None 282 None 5
Genomic Location (Zv9):
Chromosome 18 (position 14897642)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15343060
GRCz11 18 15311572
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGAAACAGGGGGCTGCTGAGTTCCTGTTTGTGCTCTGCAAGGAGAGTGG[T/A]AAGTTCTGCTTCAYAATGGTGCAGTTTTATACATAATAGTTTTCATACTW
Long Flanking Sequence:
ATTATTTGTTGCTTTTACAACTGGGATCAATGACAAGACTTTTGTCAGGGATTGTACTCTGGCAGTGTGCTGTAATGCTATTGAAAATCCTGATTGTAATGTTTAAATCCCTGTCCAATCTCACACACTGATTCATGTGTAAATCATTCAAATATTTGTGTCTTGATGCAGCAATTTTCGATTTTGATTCTCTTTAATGTGATCTGACTAAGCAGTGGCCATCAACTACTATTTATAGAATTTTCTTTATTCAAAGGAACGAGCGTATTTATGCGACTCTTCATTTTCTTTTGCACTTTAATTATTGAGTTAAAGAGTCTTTAGTTGCTGATTAAAAGTGTACTCTTTGTACAGATCTTACCTCCTCTGAAGGATGTGAAGGAAAGGCCAGAAATTGGAGACACCATTCGAAACAAACTGGTGCGTCTTATGACGCATGTAGACATGGCAGTGAAACAGGGGGCTGCTGAGTTCCTGTTTGTGCTCTGCAAGGAGAGTGG[T/A]AAGTTCTGCTTCATAATGGTGCAGTTTTATACATAATAGTTTTCATACTAAATTTTTAAGAGCGCATATTACAGTGTTTCTCAGTCGCTTTGCTACATTGTTCAGATCAGAAATGGAGAAATGCACTTACTGTTTTGCAAATTTCAAACAACGTATACAGATAGCAAAATACCATGCATTAACTGCAAAACCGTCCTCTGCTCAAAATCTTTAGTTCATCCCTTATTTCTTTCTTTAGTTCATCAACTATATTTCTATGTCAATGAACATGTCAGTGCTTTGTGTCATTGTGTACCGATAAGACTTGGTCATAATAACTTGGTCATGTTGTCAATTTAACAGTGTACTCTTGAGGGGTGTTCGATTGTAAATTTTAGCAGCTGTTTGTATTGTAATTTGTTGACAGATCATGTCATTGTGATACAAAAAAAGAAAAATAAAGCACTGCATAGCACAAAGACAAAACAAAACAAAAGTAGAAATGTAAACAACAATCTCCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17855
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000019818 Nonsense 455 536 8 10
ENSDART00000091428 None None 282 None 5
Genomic Location (Zv9):
Chromosome 18 (position 14895553)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 15340971
GRCz11 18 15309483
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAGGAGAGACGCAGTACTCRTCTGATGAAGACTCTGACACTGAGGAGTA[C/A]AAGTCYGTCAAACCATTGTAAGTGCCTTTTTGTGTATGCATAACNTTCGA
Long Flanking Sequence:
CTGTATCTTTATCCAAAGGCTGCACAAAAAAACTGATACAACAAACACAGTCCCTATAATATTGCAGTGTTCATCGTGGCACTGGTAATTTGCAACACCATCTTTTGTGTGCGTTACCTCAGATAACACACTGTATTCCTTAAAATGTTTATCATTTAGGAGTCAAATATGCCTTATAGAACTGTTGTAACTAATCATCTTGTGACAATTCTGTCAAAAATTATTTTGGTTATGACACCTGGCATGAAAATGTGTTGATTATCCCTGACACCATCTCTTTTATACATTTCGAACTGTGATTTGTGACTTTATGCTATTTAACCAAGTAAAAAAATAATTTTATGCTTTGCTCATTCTTTCCCCCGTGATGCAGTGGATAATCTGCTGAAGTACACTGGATATGGCAATGCTGCTGGGCTGTTGATGGCACGAGGGCTGCTGGCCGGAGGTAGAGGAGAGACGCAGTACTCATCTGATGAAGACTCTGACACTGAGGAGTA[C/A]AAGTCCGTCAAACCATTGTAAGTGCCTTTTTGTGTATGCATAACGTTCGAGGTTACAGAAGTAACCCTTCGTTCCCCGAGGAGGGGAACGGAAGTGCCATGAATGGGAGGATTCGGATCAGAAGCCGCTTATCTGGAGAGTATTGAACGGGCCAATGAATGAAATTAATTGGCAGCGTAAGCTTGCGCAGGTGTGCGACATCTGCAATCATCTCAGCATATAAGCACACCTGAAGCCAGCAGACGCCATCCTTTTAAGCTGAAGAGACTTTCAAACAGCTAAGGGACAGTCATTATGGCGACGGAATATGGCACTTCCGTTCCCCTCCTCGGGGAACGAAGGGTTACTTCTGTAACCTCGAACGTTCCCCTTCGGTTGGGGAACTTCAGTGCCATGAATGGGAGAATATGGAAAGCGCCATAATGACTGCACCTTACCAACACCCCCGATGAGGAGATAGTCAAGCAAGCGTGACGCACCCACATCATGGGGGGCGCGGT
Associated Phenotype:
Not determined