ZMP
cyp46a1
Ensembl ID:
ZFIN IDs:
Description:
cytochrome P450, family 46, subfamily A, polypeptide 1 [Source:RefSeq peptide;Acc:NP_001018358]
Human Orthologue:
CYP46A1
Human Description:
cytochrome P450, family 46, subfamily A, polypeptide 1 [Source:HGNC Symbol;Acc:2641]
Mouse Orthologue:
Cyp46a1
Mouse Description:
cytochrome P450, family 46, subfamily a, polypeptide 1 Gene [Source:MGI Symbol;Acc:MGI:1341877]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa23632 | Essential Splice Site | Available for shipment | Available now |
| sa17707 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa23632
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000028039 | Essential Splice Site | 314 | 501 | 9 | 15 |
| ENSDART00000081351 | None | None | 296 | None | 9 |
The following transcripts of ENSDARG00000012137 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 20 (position 5156568)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 5071935 |
| GRCz11 | 20 | 5114848 |
KASP Assay ID:
2261-3927.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAAGATCTTGAGCAGATGTTGGACAATTTTGTGACTTTCTTCATTGCTGG[T/A]GAGTTAGTGCTCATGTCGATGAACTTGAAGTGCTTTTGTTGCATACACAC
Long Flanking Sequence:
GTGGCTTTTGCTGTCAAAAGCAAGTTGCATTTAGCCCTTTTACCAACAAACTGTTATTTCTGAATGGGCGTACGCTGCGATTTAGATGATTTGCAAATCTATTTGTTTATGGTGTACTACGTGTCTAAAGCATTCACTTGTCATTATCTCATTGTTGGCAGAAGTGCTGTTTTGCATCTGAACTCTTCATATATATATTTATATATTGCTTTGTCAAAGGGCCTTGATTCTTGATCTCCCTTCTTGATTTTATTCTGTTAACAATAGACTAGATTGAAATGATACCACACTTACAGGCCAAAAATATGCAAATAAAATGACTTCTGAAGTCACTTTTTAAAATGTCTCTCATTATTTATTCTTTCTTCACTGTAGACAGTATTATTTAACAGGTAGCCTAAGACTCTTGTGTTTTGTTTTCTTGCAGAGGAGGAAAATGTTAATAACACACAAGATCTTGAGCAGATGTTGGACAATTTTGTGACTTTCTTCATTGCTGG[T/A]GAGTTAGTGCTCATGTCGATGAACTTGAAGTGCTTTTGTTGCATACACACAACCCCGCCCATAACCCCACCCCTCACAGTGATGTCAGTAGCTCTGTTGATTGCATGTGTCTGAGACGGCTTGTCTCAGCTTGCATGTCTTGCAGCCAGATACTATTGCTTTATTCTTCTGCAGGCCAAGAGACAACAGCCAATCAGCTCTCATTTGCAATCATGGCATTAGGGAGAAATCCAGAGATCTATAAACGGTAAAACACTTGTTAGAAATGTGTCCCTGTTCTGTCAGACTTTTATTATAATACTATAGTTCAATATTCCTTTCATTTCCAGAGCTAAAGCAGAGGTGGATGAAGTCCTCGGAACCAAAAGAGAAATTTCAAATGAAGACCTTGGAAAATTGACTTACTTGTCTCAGGTTGGTTCATAGAGACTTTTACATGCTACAAACACAAATGCTTTTAAATCCATTTCTTTTAATGGTCTTTTGTGTTATTCAGGTGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17707
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000028039 | Nonsense | 446 | 501 | 14 | 15 |
| ENSDART00000081351 | None | None | 296 | None | 9 |
The following transcripts of ENSDARG00000012137 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 20 (position 5160771)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 5076138 |
| GRCz11 | 20 | 5119051 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCTTATCTAAAGGCCTTATTACTGCTACTACCCATTTTCACTTGGTCCA[C/T]GAACCTGTCTTGGCCAGGTCTTCGCACAGGTGATGAAACACACACATGCA
Long Flanking Sequence:
GATTTAAATCAGCCTTTAGGCTTGATAGGCTTGCTCATGTTGCTCCTCAATCTGGCAACCTGCCTGAATACCTATATAGGTAGTTCAACCACTAGGTGTCAAACTTACATACTGCACCTTTAAATTAGCGAATTAAGTGGAAATTTCAATTTTTAGGTGAACTTTTCCCTCAGTTTTTTGGGTGACCTATCCTTTTATGACATTAACAATAGTCCCATGTAGGATTTACTAAACAGAAATATAACAAGAGACCTGCTTAATTGAACAAGTGCAGTTTTTCTACTTAATGTTACAGCGGCAGGTTGATAGCAGCTCTTTAAAATTCAGATTTTACAATGTTTGAGTTGAAAATAACTAATCGTGAGTTTAAGAAGTGTGTCAGAATTGTATCACTTAAACACTACTTTATTTAATTACATTATAGCATGACAACGCTGATTTCAAATTGTTTTCTTATCTAAAGGCCTTATTACTGCTACTACCCATTTTCACTTGGTCCA[C/T]GAACCTGTCTTGGCCAGGTCTTCGCACAGGTGATGAAACACACACATGCATACATCCACATATTGGTTTTGGTGGATTATGAGGAATCTCCATTGGCATAATGTATTTTGAACATGCTTTTTTTATTGCCTTACCCTAACACTAAACCCGTCCCTCATAGGAATCCTGTTGCAAAAAAAAATAAATTTTATTTATTTTTTTTTACAATTTTGAATGTTGAGGACTCAAGGCATGTCCCCATAAACTACTTTAACATCGTAAGAGCAACATTGGCCCCTTTCACACATACAGACCTTTCCGGAAAATTACCAGCAATTTTCCGGAAAGGTCTGTATGTGTGAACAGGTCCTTTTTGAAAATACCGGTAAATTCGTTCTGGCTATTTTCCGGAAAGAGAAGTTGTAACATTACCGGCAATTTGCCGGAATGCTGCGCTGTGTGAACGCAGAAGGAAGATTGACGGAATAAGCGCGTGCACGTCTAGAACGTGCTGACGTGAG
Associated Phenotype:
Not determined