Busch Lab

ZMP

gad1b

Ensembl ID:
ENSDARG00000027419
ZFIN ID:
ZDB-GENE-030909-3
Description:
glutamate decarboxylase 1 [Source:RefSeq peptide;Acc:NP_919400]
Human Orthologue:
GAD1
Human Description:
glutamate decarboxylase 1 (brain, 67kDa) [Source:HGNC Symbol;Acc:4092]
Mouse Orthologues:
AC101882.1, Gad1
Mouse Description:
glutamic acid decarboxylase 1 Gene [Source:MGI Symbol;Acc:MGI:95632]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa15783 Nonsense Available for shipment Available now
sa17561 Essential Splice Site Available for shipment Available now
sa2304 Nonsense Available for shipment Available now
sa13138 Nonsense Available for shipment Available now
sa900 Essential Splice Site Available for shipment Available now
sa20613 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa15783
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
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Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003008 None None 587 None 17
ENSDART00000122348 Nonsense 290 613 9 17

The following transcripts of ENSDARG00000027419 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 3665244)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 3689548
GRCz11 6 3850368
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTTAAACACAGCGGCTGTCTCCCTCTAGAGGACAGCATTATTAATGCGG[G/T]AAAGTGGATCTGTTTTGGACCATTTGATTGATGGCCGKCCATTWCTTTTT
Long Flanking Sequence:
TAAACTGATCACAAATTCAATTCAATTCACCTTTATTTGTACAGGGTATATTATACTACAAAACACCACATATTACTGTAAAAACTACAGTCCCTTATATTATAATATTTAATACAGTTTACTATAGTTAATACAGCATGATGTAACATTCATTAACAAGTAGTTGTGAATACTATAATTTATACAGTATAATATACTTCACATGGTTCAAAAACTCTAGCACATAGTATCTTTTCATGTTGGATGTATCCGGGAAAGCAGTTGATGCTAAACGCAGTCGTCTTTTCACAGGTGGTGCCATATCAAACATGTACAGTGTGATGGTTGCGCGGTATAAATATTTCCCTGAAGTCAAAACCAAAGGCATGTCTGCGGCTCCGCGGCTCGTGCTGTTCACATCTGAACATGTAAGTGCACACAGACTGTAGAATACATGTAAGTGTACATTACTGTTAAACACAGCGGCTGTCTCCCTCTAGAGGACAGCATTATTAATGCGG[G/T]AAAGTGGATCTGTTTTGGACCATTTGATTGATGGCCGGCCATTTCTTTTTTCGCAGAGTCATTACTCAATCAAGAAGGCAGGAGCTGTTCTTGGATTTGGCAAAGAAAACGTCATTCTCCTGAAGACAGATGAGAGGTATGGCGTACAGTGTATACCTGACATGTTTATTATAATTTTGTAATTATGAATGTATGGAAACTTCAAAGAACATAGCACAGTTTATTTGAAATAAAATAATGACAATGGATAATAATGTTACTGATGAGGGCAAAATTATTAGCCCTCTTGTGAAATATTGATTCTTTTTCAACTATATTTTTCAATGGAGCAAGGACATTTTCACAGTATTTCCTATAATAATATTATTTCTTCTGGAGAAAGTCTTATTAGTTTTATTTTGGCTGGAATAAAATATGTTAAGGTCAATATTATTAGCCCCTTTAATATTTTTCCCAATTAGTTACAGAAATGTGTTGGAAAAAACCTCTCCATTAACAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17561
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003008 Essential Splice Site 309 587 None 17
ENSDART00000122348 Essential Splice Site 335 613 None 17

The following transcripts of ENSDARG00000027419 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 3665382)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 3689686
GRCz11 6 3850506
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCTTGGATTTGGSAAAGAAAACGTCATTCTCCTGAAGACAGATGAGAGG[T/C]ATGGCGTACAGTGTAYACCTGACATGTTTATTATAWTTTTGTAATTATGA
Long Flanking Sequence:
TGATGTAACATTCATTAACAAGTAGTTGTGAATACTATAATTTATACAGTATAATATACTTCACATGGTTCAAAAACTCTAGCACATAGTATCTTTTCATGTTGGATGTATCCGGGAAAGCAGTTGATGCTAAACGCAGTCGTCTTTTCACAGGTGGTGCCATATCAAACATGTACAGTGTGATGGTTGCGCGGTATAAATATTTCCCTGAAGTCAAAACCAAAGGCATGTCTGCGGCTCCGCGGCTCGTGCTGTTCACATCTGAACATGTAAGTGCACACAGACTGTAGAATACATGTAAGTGTACATTACTGTTAAACACAGCGGCTGTCTCCCTCTAGAGGACAGCATTATTAATGCGGGAAAGTGGATCTGTTTTGGACCATTTGATTGATGGCCGGCCATTTCTTTTTTCGCAGAGTCATTACTCAATCAAGAAGGCAGGAGCTGTTCTTGGATTTGGCAAAGAAAACGTCATTCTCCTGAAGACAGATGAGAGG[T/C]ATGGCGTACAGTGTATACCTGACATGTTTATTATAATTTTGTAATTATGAATGTATGGAAACTTCAAAGAACATAGCACAGTTTATTTGAAATAAAATAATGACAATGGATAATAATGTTACTGATGAGGGCAAAATTATTAGCCCTCTTGTGAAATATTGATTCTTTTTCAACTATATTTTTCAATGGAGCAAGGACATTTTCACAGTATTTCCTATAATAATATTATTTCTTCTGGAGAAAGTCTTATTAGTTTTATTTTGGCTGGAATAAAATATGTTAAGGTCAATATTATTAGCCCCTTTAATATTTTTCCCAATTAGTTACAGAAATGTGTTGGAAAAAACCTCTCCATTAACAGCACTTGGGTGAATTTTTATTTAGAAAATTATAATGTACACAATAAGATTACTAATTCTGATTTCAACTGTTCTTTGCTGAAAAATTTCTCCTTCTTTTGTTTTTTGACAGTACTTACTGCAAACTTATGGACCTCTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2304
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003008 Nonsense 439 587 14 17
ENSDART00000122348 Nonsense 465 613 14 17
ENSDART00000003008 Nonsense 439 587 14 17
ENSDART00000122348 Nonsense 465 613 14 17

The following transcripts of ENSDARG00000027419 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 3671259)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 3695563
GRCz11 6 3856383
KASP Assay ID:
554-2874.1 (used for ordering genotyping assays)
KASP Sequence:
ATGTGCGCAGGTTACCTCTTCCAGCCGGACAAACAGTACGACGTGACCTA[C/A]GACACCGGAGACAAGGCCATCCAGTGCGGCAGACATGTGGACATCTTCAA
Long Flanking Sequence:
CATCGTCACAAGCTGAGCGGCATTGAGAGGTCTGTATGTGACAATGACTAAAACTAATGTAAATCACAATACAGCTGCAGTGAGAGCTGAAAACCCACTTATCTGTGTGTGTTTCAGGGCAAACTCCGTCACGTGGAACCCTCATAAGATGATGGGTGTGCCTTTACAATGTTCAGCCATCCTGGTCAGAGAGAAGGTGAGACCTGAAAAGTTATCACAATGATATTTGCTTTTCAAATATTTCCAAAATCCATCCATAAATTTGGTTGTTAACCCTTTATAGTATATGAAACTTATTGAAATACTTTTACTGGAGGTTACTGCAAGACCTTTGAACTTTTATGACATAAACGTGTCAAAAATCAGGTGGGCAGGTGAATAAGAGTTAAATATGATAAAATAAGGATGTCTGCTCTTCTGTTCCAGGGCATTCTCCAGGGCTGCAACTCCATGTGCGCAGGTTACCTCTTCCAGCCGGACAAACAGTACGACGTGACCTA[C/A]GACACCGGAGACAAGGCCATCCAGTGCGGCAGACATGTGGACATCTTCAAATTCTGGCTCATGTGGAAGGCCAAGGTTGGTCACAGTAGCACATTAAATCTGGTCCTGATACACATCATAGCTAAACAGCTTAAAGAAATATCTATGTTAATGTTTACAATGTCTTAACATGATTTAGTCACAATGAGCATACATTTATATGAATTTTGTGATCTAATTAATCTATATACAGTATAATTTTTTCTATTAAAAATAAAAGTATAATATGTTAAGGATAAAGTACATCCAGGAGGTTTTGAATCACAGAATAAAGCCATTGTTGAATAAAACTGAAGGCCTTTACTCTGTGAAAACAGCCATCCTGAATGTTCTTTGTCTCACTGATTACACTGCTACTTGCTCACAAAACATACAAATTAATCACAAGCCATTGTTCTGTACTGCTATAAAGCTGACAGAAACAAAAACAGCTGATGGAGGATACACTATCCCGCGCATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13138
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003008 Nonsense 439 587 14 17
ENSDART00000122348 Nonsense 465 613 14 17
ENSDART00000003008 Nonsense 439 587 14 17
ENSDART00000122348 Nonsense 465 613 14 17

The following transcripts of ENSDARG00000027419 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 3671259)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 3695563
GRCz11 6 3856383
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGTGCGCAGGTTACCTCTTCCAGCCGGACAAACAGTACGACRTGACCTA[C/A]GACACCGGAGACAAGGCCATYCAGTGCGGCAGACATGTGGACATCTTCAA
Long Flanking Sequence:
CATCGTCACAAGCTGAGCGGCATTGAGAGGTCTGTATGTGACAATGACTAAAACTAATGTAAATCACAATACAGCTGCAGTGAGAGCTGAAAACCCACTTATCTGTGTGTGTTTCAGGGCAAACTCCGTCACGTGGAACCCTCATAAGATGATGGGTGTGCCTTTACAATGTTCAGCCATCCTGGTCAGAGAGAAGGTGAGACCTGAAAAGTTATCACAATGATATTTGCTTTTCAAATATTTCCAAAATCCATCCATAAATTTGGTTGTTAACCCTTTATAGTATATGAAACTTATTGAAATACTTTTACTGGAGGTTACTGCAAGACCTTTGAACTTTTATGACATAAACGTGTCAAAAATCAGGTGGGCAGGTGAATAAGAGTTAAATATGATAAAATAAGGATGTCTGCTCTTCTGTTCCAGGGCATTCTCCAGGGCTGCAACTCCATGTGCGCAGGTTACCTCTTCCAGCCGGACAAACAGTACGACGTGACCTA[C/A]GACACCGGAGACAAGGCCATCCAGTGCGGCAGACATGTGGACATCTTCAAATTCTGGCTCATGTGGAAGGCCAAGGTTGGTCACAGTAGCACATTAAATCTGGTCCTGATACACATCATAGCTAAACAGCTTAAAGAAATATCTATGTTAATGTTTACAATGTCTTAACATGATTTAGTCACAATGAGCATACATTTATATGAATTTTGTGATCTAATTAATCTATATACAGTATAATTTTTTCTATTAAAAATAAAAGTATAATATGTTAAGGATAAAGTACATCCAGGAGGTTTTGAATCACAGAATAAAGCCATTGTTGAATAAAACTGAAGGCCTTTACTCTGTGAAAACAGCCATCCTGAATGTTCTTTGTCTCACTGATTACACTGCTACTTGCTCACAAAACATACAAATTAATCACAAGCCATTGTTCTGTACTGCTATAAAGCTGACAGAAACAAAAACAGCTGATGGAGGATACACTATCCCGCGCATTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa900
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003008 Essential Splice Site 501 587 16 17
ENSDART00000122348 Essential Splice Site 527 613 16 17

The following transcripts of ENSDARG00000027419 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 3673829)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 3698133
GRCz11 6 3858953
KASP Assay ID:
554-0807.1 (used for ordering genotyping assays)
KASP Sequence:
AGCTAATACTGCTGCTAATGGGTTTTTTATTGCTTTCCTCTGCTCTCCAT[A/T]GCCCCAGCACACTAATGTTTGCTTCTGGTATATTCCACCGAGTCTGCGTG
Long Flanking Sequence:
TAAAAGGGTGGCTGATATTATACTTACATTTTGTGATCGAGTAATTTTTTTTCTATATAATGTAATTCGGTTTATGAGGGATAAAGCTGGAAATAAAATAATAAACATCCAGTTATAGTGTTGTGCAATAAACCAGATGGTAAATATTATAATCACACGAGTCTACTTTATATATGCAGATGAAGTAGAATGTTTTATACAGCCATTTTCCGCTATCAAATCAGTGATGTGGCTTTAGCAATAAGTATTTAGCTGAGAAAAGAGCTTCATTGGGATTGTTGAATTTGATTTGTGCAGGGCACGATTGGGTTCGAGCAGCACATTGACAGATGTCTGGAGCTTTCTGAATATCTCTACAATAAAATCAAGAACCGTGAGGGATATGAAATGGTCTTTGAGGGCCAGGTTTGTATCTGGAACATACACATTTATTGATTCGAAGAAGTGCTTAGCTAATACTGCTGCTAATGGGTTTTTTATTGCTTTCCTCTGCTCTCCAT[A/T]GCCCCAGCACACTAATGTTTGCTTCTGGTATATTCCACCGAGTCTGCGTGGCATGCCGAACGGAGACGAGCGAAGGGAGAAGCTGCACAGGGTACGTCGTCTCATCAAATTGGAATGAATGAATGAATGAAAAAGTATGAATGAAAGAATGATGAATAAATTAATAATTAATGAATGAAAAAGAAAGAAATATGAAACAATAAATGAATGAATTAATTAATTCATTCATTAAAAAGTATAAATAAAAGAATGACGAATAAATTAATAATTAATGAATAAAAAAGAAAAATATGAAGAAATAAATGAATGAATTAATTAATTATTTAATGAAAAAGTATGAATAAGAGAATGACGAATACATTTATAATTAATGAATAAAAAAGAAAAATATGAAACAATAAATGAATTAATTAATTAATTAATTAAAAAGTATGAATAAAAGAATGACGAATAAATTAATAATTAATGAATGAAAAAGAAAGAAATATGAAACAATAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20613
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000003008 Nonsense 542 587 17 17
ENSDART00000122348 Nonsense 568 613 17 17

The following transcripts of ENSDARG00000027419 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 6 (position 3675554)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 3699858
GRCz11 6 3860678
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGACTCTCCTGCAGGTGGCGCCAAAAATCAAAGCAATGATGATGGAGTG[C/A]GGCACCACCATGGTGGGTTACCAACCACAGGGAGACAAAGTCAACTTCTT
Long Flanking Sequence:
AATTAATGAAAAAGTATGAATAAAAGAATGACGAATAAATTAATAATTAATGAATGAAAAAGAAACAATAAATGAATTAATTAATTAATGAAAAAGTATTAATAAAAGAATGATGAATAAATTAATAATTAATGAATGAAAAAGAAAGAAATATGAAACAATAAATGAATGAATGAATTAATTAATTAATTAATGAAAAAGTATGAATAAAAGAATGATGAATCTTCATTTGCATAAAGTTGAAGGATTCTCAACTTTGTCGTGTCGCTCGACACGCCGACCTGGTTGCCAACAATGGCCGTTGCTCTCATAGACATAGTCGTACAGAGGTCGCTTACTCTATGCTGAAATAAACAGTCGCTTTTTGCTCTGCCTTTGCAAGTCGCTCATATTGTGAATGAGGCTTAAGACTCCCTATTGAAAAAATGTGGGCTCTCATTAAAACCCTCTGTGACTCTCCTGCAGGTGGCGCCAAAAATCAAAGCAATGATGATGGAGTG[C/A]GGCACCACCATGGTGGGTTACCAACCACAGGGAGACAAAGTCAACTTCTTCCGAATGGTGGTCTCCAATCACGCCGTCACCAAGTCGGACATCGATTTCCTCATCGATGAGATCGAGCGGCTCGGTCAGGATCTGTAAAACATCTATAATAGAGGCTCATTGGTCGCCTACGCGTTTAACGGCTATGTTTCGACGTTGTGTAGTTCTGTCCTTTCTTCTCAATGTCTTTAGATCTTTATATTACAGATTGCATAGCCTGTATAGCTACACAGTCACCTTACGACATATAGTCCATTGGGATAACAGCCGGTGCTTGTAAATACTATGAAGTCGAGCAAAAGCACAGCACTCTTTTAACGAAGCCCCTTTCGGTGTAATAGTGGGGTCTGTGTGTAAACCAGTGGTGGGTCTGTATTTTAGTGTTGTGTTTTTTAGATCTTCCCTTGTCGTAGGTCTTGTAAAGTGTTTAATCAGCACCTTTGTGAGGTGAAACATAAGTA
Associated Phenotype:
Not determined