Busch Lab

ZMP

myhb

Ensembl ID:
ENSDARG00000001993
ZFIN ID:
ZDB-GENE-081124-1
Description:
LOC100002040 protein [Source:UniProtKB/TrEMBL;Acc:A7E2L9]
Human Orthologues:
MYH6, MYH7
Human Descriptions:
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Mouse Orthologues:
Myh6, Myh7
Mouse Descriptions:
myosin, heavy polypeptide 6, cardiac muscle, alpha Gene [Source:MGI Symbol;Acc:MGI:97255]
myosin, heavy polypeptide 7, cardiac muscle, beta Gene [Source:MGI Symbol;Acc:MGI:2155600]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa31534 Essential Splice Site Available for shipment Available now
sa25345 Nonsense Mutation detected in F1 DNA Not yet available
sa18118 Nonsense Available for shipment Available now
sa17247 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa31534
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026257 Essential Splice Site 684 1939 17 39
Genomic Location (Zv9):
Chromosome 6 (position 40682742)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 40754342
GRCz11 6 40751878
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AATGATCATCCTCTCTAAAACAATGATTTATTATTAACTCTCTTTATTTT[A/G]GGTCTTATGGAGAACTTTCTGGTCATCCACCAGTTGCGTTGTAATGGTGT
Long Flanking Sequence:
CATACTGTTACGATTACAACATTAGGATTCAAATATTTTTTTTGTTATGTATAAATTTCTGTTAAAGATAATTTCTGCTTGATTTCGGTACATGGTATTGTTTACCAAGATTATTTACTTATTTCTTTATCGACAGCTGAATCTGGTGGCAAAAAGGGTGGAAAAAAGAAGGGAGGCTCCTTCCAGACTGTGTCTGCTTTGTTCAGAGTAATGAAATGATTCACTTTTAGCCTTGAAATATTTAAGGTGCACTGTGTGTTTATAGTTTAACTGTTTATTCTACAATTAACAGGAAAATTTGGGCAAATTGATGACCAACCTGAGAAGCACTCATCCACATTTTGTGCGCTGCTTGATTCCAAATGAGTCAAAGACTCCAGGTCAAATTTTTGACACAACTTTTTTTAAAATACAGAAAAGCATGTGACATATACTCTTTGTTAAAATAACAATGATCATCCTCTCTAAAACAATGATTTATTATTAACTCTCTTTATTTT[A/G]GGTCTTATGGAGAACTTTCTGGTCATCCACCAGTTGCGTTGTAATGGTGTGCTGGAGGGAATCAGAATTTGCAGAAAGGGTTTCCCCAGCAGAATCCTCTATGGTGACTTTAAGCAGAGGTAATTAATGTGCATGACTTGTATTTCACTTGTCTTTGGTGAATTTAATATGTAAAATTGTGTGCATGGGCATTACCTGGATTATTGTACAGTGAATGTTGAGCATGTGCCCAACTCTATTAATCTTGATAAAATATCTCGGCTTTCTTTAATACACATGTCTGTCTAAATAAATGGAAACACACACAGTATGCAGATTGTGTGTACAAAGGCATGTGGATCTTCACAAGTATAGTGAATAAGACTGAGTCATATCTTCACTTTAGATACAAAGTATTGAATGCTAGTGTCATCCCTGAGGGTCAGTTCATTGACAACAAGAAGGCTTCAGAGAAGCTTCTTGGCTCTATTGATGTGGATCATACCCAGTACAAGTTTGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25345
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026257 Nonsense 1579 1939 32 39
Genomic Location (Zv9):
Chromosome 6 (position 40678338)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 40749938
GRCz11 6 40747474
KASP Assay ID:
554-7299.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTTCGCGTTCAGCTTGAACTGAACCAAGTGAAAGGAGAGATTGATCGG[A/T]AATTGGCCGAGAAGGATGAGGAGATTGAACAGATTAAGCGAAACAGCCAG
Long Flanking Sequence:
ACTTAGCACGGAACTTTTCAAAATGAAAAATTCTTATGAGGAGACTTTGGATCATCTAGAAACTCTTAAGAGAGAGAACAAGAACCTTCAGCGTATGTACAATTAAGTGCAGAACTATATGTTGTTGTTTTTTTTTTTGCTTTTTAGACGTAAATAGTGCATTTCACCCAATTGTTGGTCATGTTTTTGCATATACAGAGGAAATCACAGATTTAACCGAACAGCTTGGCGAGACTGGAAAGACCATCCATGAGCTGGAAAAAGGAAAGAAAACTGCAGAAATCGAAAAATCTGAAATCCAAGCTGCTCTTGAAGAAGCTGAGGTAACACCTAGGCCCTAGTGCTTAAAGTTTTTTTTTTATTCCCAATATCACCACTAAACTTCCAGCGAACAATACACTACACACCATCCTATTTTTCAGGCCACCTTAGAGCATGAGGAATCCAAGATTCTTCGCGTTCAGCTTGAACTGAACCAAGTGAAAGGAGAGATTGATCGG[A/T]AATTGGCCGAGAAGGATGAGGAGATTGAACAGATTAAGCGAAACAGCCAGAGGATCATCGACTCTATGCAGAGCACTCTGGATGCGGAAGTCAGAAGCAGAAACGATGCTCTGAGAATCAAAAAGAAGATGGAAGGAGACCTGAACGAGATGGAGATTCAGCTAAGCCATGCAAACCGGCAGGCAGCTGAAGCTCAGAAGCAGCTCAGGAACGTCCAAGGGCAACTCAAGGTTTGTTCCTTTAGAGTAGTATAGCAGTATATCTTGATTTGACTAACTAGATCAAACAATCTAATTGAAACTTGATTGCTTCAGGATGCTCAACTCCATCTTGATGAGGCTCTGAGGGCTCAAGAGGACATGAAAGAACAAGTTGCAATGGTTGAACGCAGGAATAACCTGATGCAGGCAGAGATCGAGGAGCTGAGAGTTGCTCTGGAGCAGACCGAGAGAGGCCGCAAAGTGGCTGAGCAGGAACTGGTGGATGCCAGTGAGCGAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18118
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026257 Nonsense 1624 1939 32 39
Genomic Location (Zv9):
Chromosome 6 (position 40678203)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 40749803
GRCz11 6 40747339
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CKGAAGTCAGAAGCAGAAACGATGCTCTGAGAATCAAAAAGAAGATGGAA[G/T]GAGACCTGAACGAGATGGAGATTCAGCTAAGCCATGCAAAYCGGCAGGCA
Long Flanking Sequence:
TTTGCTTTTTAGACGTAAATAGTGCATTTCACCCAATTGTTGGTCATGTTTTTGCATATACAGAGGAAATCACAGATTTAACCGAACAGCTTGGCGAGACTGGAAAGACCATCCATGAGCTGGAAAAAGGAAAGAAAACTGCAGAAATCGAAAAATCTGAAATCCAAGCTGCTCTTGAAGAAGCTGAGGTAACACCTAGGCCCTAGTGCTTAAAGTTTTTTTTTTATTCCCAATATCACCACTAAACTTCCAGCGAACAATACACTACACACCATCCTATTTTTCAGGCCACCTTAGAGCATGAGGAATCCAAGATTCTTCGCGTTCAGCTTGAACTGAACCAAGTGAAAGGAGAGATTGATCGGAAATTGGCCGAGAAGGATGAGGAGATTGAACAGATTAAGCGAAACAGCCAGAGGATCATCGACTCTATGCAGAGCACTCTGGATGCGGAAGTCAGAAGCAGAAACGATGCTCTGAGAATCAAAAAGAAGATGGAA[G/T]GAGACCTGAACGAGATGGAGATTCAGCTAAGCCATGCAAACCGGCAGGCAGCTGAAGCTCAGAAGCAGCTCAGGAACGTCCAAGGGCAACTCAAGGTTTGTTCCTTTAGAGTAGTATAGCAGTATATCTTGATTTGACTAACTAGATCAAACAATCTAATTGAAACTTGATTGCTTCAGGATGCTCAACTCCATCTTGATGAGGCTCTGAGGGCTCAAGAGGACATGAAAGAACAAGTTGCAATGGTTGAACGCAGGAATAACCTGATGCAGGCAGAGATCGAGGAGCTGAGAGTTGCTCTGGAGCAGACCGAGAGAGGCCGCAAAGTGGCTGAGCAGGAACTGGTGGATGCCAGTGAGCGAGTGACTCTCTTACACTCCCAAGTAAGAAGAATGATTTATTTTGAAGAATGTTTTAAAGAATAACTGTTAAACAACATTACCTTTAACTTGATCTCAATGTCCGCAGAACACCAGTCTTATTAACACCAAGAAAAAGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17247
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000026257 Essential Splice Site 1765 1939 34 39
Genomic Location (Zv9):
Chromosome 6 (position 40677608)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 40749208
GRCz11 6 40746744
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCCAGGAAGCTCRAAATGCTGAAGAGAAGGCAAAGAAAGCTATAACTGAT[G/T]TAAGTAAATCTGTTCATGGATAATTNNNNNNNAAGTTTTCAAGATGTTGCATGTAAA
Long Flanking Sequence:
GGTTTGTTCCTTTAGAGTAGTATAGCAGTATATCTTGATTTGACTAACTAGATCAAACAATCTAATTGAAACTTGATTGCTTCAGGATGCTCAACTCCATCTTGATGAGGCTCTGAGGGCTCAAGAGGACATGAAAGAACAAGTTGCAATGGTTGAACGCAGGAATAACCTGATGCAGGCAGAGATCGAGGAGCTGAGAGTTGCTCTGGAGCAGACCGAGAGAGGCCGCAAAGTGGCTGAGCAGGAACTGGTGGATGCCAGTGAGCGAGTGACTCTCTTACACTCCCAAGTAAGAAGAATGATTTATTTTGAAGAATGTTTTAAAGAATAACTGTTAAACAACATTACCTTTAACTTGATCTCAATGTCCGCAGAACACCAGTCTTATTAACACCAAGAAAAAGCTGGAAGCAGATCTTGTTCAGATTCAAGGTGAGATGGAGGACGTGGTCCAGGAAGCTCGAAATGCTGAAGAGAAGGCAAAGAAAGCTATAACTGAT[G/T]TAAGTAAATCTGTTCATGGATAATTAAGTTTTCAAGATGTTGCATGTAAACTAAAAACTGGGTTAAAAAAATATATCAGGCCGCCATGATGGCAGAGGAGCTGAAGAAGGAGCAGGACACAAGCGCTCACCTTGAGAGGATGAAGAAGAATCTGGAGGTTACAGTCAAAGACCTGCAGCACCGTCTGGATGAGGCTGAGAGTCTGGCTATGAAGGGTGGAAAGAAGCAGCTCCAGAAGCTGGAGGCCAGAGTATGTGACTGCTCACACTGTTCATTGATTTACCTCACCGTAAGTCAGGAATAACCTCAGTTAAACTTGTGCGTCAGGTTCGTGAACTGGAGAGTGAAGTCGAAGCTGAACAGAGACGTGGTGCTGATGCTGTGAAAGGAGTCCGCAAATATGAAAGAAGAGTGAAGGAACTGACTTATCAGGTAATAATAATCACACAAATAAACGTATATAGGTGTTATAAGTCAAATACAGTCAAATCAAAATGGTT
Associated Phenotype:
Not determined