ZMP
cobra1
Ensembl ID:
ZFIN ID:
Description:
cofactor of BRCA1 isoform 2 [Source:RefSeq peptide;Acc:NP_956462]
Human Orthologue:
COBRA1
Human Description:
cofactor of BRCA1 [Source:HGNC Symbol;Acc:24324]
Mouse Orthologue:
Cobra1
Mouse Description:
cofactor of BRCA1 Gene [Source:MGI Symbol;Acc:MGI:1931035]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20444 | Essential Splice Site | Available for shipment | Available now |
| sa17245 | Nonsense | Available for shipment | Available now |
| sa12379 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa20444
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000051433 | Essential Splice Site | 34 | 591 | 1 | 15 |
| ENSDART00000051471 | Essential Splice Site | 34 | 583 | 1 | 13 |
| ENSDART00000133949 | Essential Splice Site | 34 | 577 | 1 | 13 |
Genomic Location (Zv9):
Chromosome 5 (position 31198145)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 28959502 |
| GRCz11 | 5 | 29559655 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACTCTGACTAACTGTACTGAACCTCTCAAAGCAATCGACCAGTTTCAGG[T/C]TAGATCTTTACAAACGTACACATGTCCTGTCTGTCATGTTCGTGATTACA
Long Flanking Sequence:
CCCTGAATACCGACATGCGCTGGAACCCACATTAAATGAACTATTACTCCCATATGTGTTAGATTATTAAACTTGATCATAATTTCTGTTAGAATGTCATTTCTTTTCGATTCCATTGTCTCAGATCGACCAGCACCTGCAATTGCCTTTACACACAGGAAGTAGTCCACACAGAGGCTTTGATCTTGAAAGCGCAACTAGGAACCTTTCTGAACCGGAACCTTTGACGATGTATCAGAAACAAGAGTCTGTTGACGAGGCTGCACGGCCAGGAAGTGTGCGATTTACAGATAACGAGCAATGCACATCTAGCCAACATTTATGTTATTTCTGCTGTCAATGCATGTAATTTGATATCGTTTTGAAAGTGGAGCCTTCACTTAGAGAGCGTGTGAAAATGTTCGCCGGGTTACCGGAGCTGGGAATATCCAATGGAGAGGATCTGAAAGAAACTCTGACTAACTGTACTGAACCTCTCAAAGCAATCGACCAGTTTCAGG[T/C]TAGATCTTTACAAACGTACACATGTCCTGTCTGTCATGTTCGTGATTACATTTTTCATCAGATGTCTTGCATTAGCCATAAAGCACCTCACGCTCGTGCTGCAGTCTTCTTCATTGTTTATAATGGGAGGATCTAATGTCTGCCAGCGCAATTCATCATTTGACAACCTGTTACCATACATATTGCCATATATAACATAACTAACATAATATAATATTAATATTAACTAATAATAAAACATATATAATAACCTCCCCGCAATATATCTCTTGAGCTCGTTTTAGTTACGTTACTCCTAAGCAGTTCCTTTTAGGACCTCATAACTTGAACGTACTGATAACTAAAAAAAAAGTATTAATACTTAATGCTTACTCTTGTTAAAAAAAAGTATTTAGGCTTAAGAGGTAAGATTGGGTCTTAATATAAAAAAAGGGGTCCTGCTTTTCTCTTAAAGCTCTTAAATACTTGGTGTCATTGCTTGATAATGGTGATGTTTTATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17245
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000051433 | Nonsense | 293 | 591 | 6 | 15 |
| ENSDART00000051471 | Nonsense | 293 | 583 | 6 | 13 |
| ENSDART00000133949 | Nonsense | 293 | 577 | 6 | 13 |
Genomic Location (Zv9):
Chromosome 5 (position 31192395)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 28953752 |
| GRCz11 | 5 | 29553905 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTAAACGGGCCMGAGAGTTACAAGGCTTTTTGGATGGTGTGAAGAAAGGC[C/T]AGGAGCAAGTGTTAGGGTATGAGATTCAWWTTTAATTCTACAGACAAGAG
Long Flanking Sequence:
GCCTATATAAGCATGTATACATATGTATATTTATGTATATATGTATTATTATTATTATTATTATTTTTTTTTTTTCCCACTGGTTATATGTTTCTAAAAAAAAAAAAAAAAAGTATTTTTAAAAAGTCAGTTTTAAACTGTTTTAAAAGTGATTTTATATTCAAAATTAGGAAAGAAATGAAAATAAAGATTGGTAATAACCAAAAACAAGAAGCGAAAAACAAGTTCATTGGGGATTATCTGGAATGTTGAATGACTAGATTAATTTCTTACAAAGATATAGCAAATAAAATCTCATTCTTGTCAGTGGTCACTTTATAAACCTATGCTGTGCATCAAAAGCTTAACACGCAGAATCATACACAATCAGAAAAGTAACAGCGTTTCTGTTTGCTCTTTTGTAGTTTTCCTGGTGTTTGGATGCCTGCATCAGGGAGAAGTTTGTGGATGCTAAACGGGCCAGAGAGTTACAAGGCTTTTTGGATGGTGTGAAGAAAGGC[C/T]AGGAGCAAGTGTTAGGGTATGAGATTCAATTTTAATTCTACAGACAAGAGGCAACCCAGTGTATAGTAAACCTATAGAAGTTTACAATGTAACACTGTCTGTGTTTCCTCAGTGACCTTTCTATGATCCTCTGTGACCCCTTTGCCTGTAACACACTGGTGTTGAGCACTGTTAGGAACCTTCAGGAGTTGTTGAGTCAGGACGCCCTGCCCAGAGTAAGACCTCCAGCTTCATCTCTGCACTACACTACACATATTTCTTATTTCCATTGATTTTAGTGCTCTACAGTGTTGTTAATGTTAACTAAAATGTTGTACTGCACAATTTATTAACATGAACTAGTATCTTAATGATTTTTATTGTTAATATATAATATATTAATTAAATGTTAGATTAAATGAAAAGATTTGCTATTTCATTTACATAAACAAAAGTTATTAAATTTTATCATTTATATATGTATTATATGATTAATATAAATATAATGTATTGTGTTTGTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa12379
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000051433 | None | 378 | 591 | 9 | 15 |
| ENSDART00000051471 | Nonsense | 378 | 583 | 9 | 13 |
| ENSDART00000133949 | Nonsense | 378 | 577 | 9 | 13 |
Genomic Location (Zv9):
Chromosome 5 (position 31191412)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 28952769 |
| GRCz11 | 5 | 29552922 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTGCCTTCAGGATCTGGAGGTGGTGACACGCTTTCTGCCTGCCATGATGT[C/A]RATAGTGGTGGACGACTACACGTTTACWGTRGAGCAGAAACWGCCGAGCG
Long Flanking Sequence:
TAATGTATTGTGTTTGTTAATGGATTAGATAGTGTTGACAAATCACTGCTAATTTTAACACTAGAAAGACATAAGTATAAACATCCGGAAAAAAAAGAAATGTCTCATTAGTGGAAGTACTAACATTTCTAAAGCTGAATTAAAATAAAACTAATTATAAAACACAACAAAATTATTTAAAGTAAGTTAAAAACTGATAAAAACATCAAAGTATAAGCGATATGAACGCATACGGCAATAGTATATGTGTAATGCTGAAATATCTGTGCTTTGTGTGGATTTGCAGGACAGTCCTGACCTTCTCCTCCTGCTGCGGATGCTCTCTCTGGGGCAGGGCGCCTGGGACATGATCGACAGTCAGGTTTTCAAAGAGCCTCGAATGGTAAGATCAGCCCTCAACAGTCTAATGTTTGAAATGGATTTGTCCGGTTTACACAAGGTGGGTCTTGCTTGCCTTCAGGATCTGGAGGTGGTGACACGCTTTCTGCCTGCCATGATGT[C/A]GATAGTGGTGGACGACTACACGTTTACTGTAGAGCAGAAACTGCCGAGCGAAGAGAAGACTTCTCTCGCATACCCCAGCACCCTGCCTGAAACCTTCTCCAGGTGTCTGTTTTATCCCATGTTGCAACCAATAATAATTAAAAAACTATTATAAGAACTAAAACCACACACAGACTCCAGAATGTGTGACACTTATTGTGTTTTTAATGTTCATGAGGACAGAAAAATCTGAACTTTGTTTCATCATTTTATTTGAGAAAACTAGCATCATAAACACTGAAAGCAACGATCTTTTCAATATTTCATCTAAATAAAAGTGTGATTTAACTTGAAGTGTTTAAACAGTTTATTTAAGCAACTTATATGTGTAAAACTATGAAATGGTAATTAATAATCATATATTATACAGAAATTATTAAAAAACTTAATATTGATACAATTACAGTGCATAAATATAGTGCAAGTCAATATTCTAGTCAGGATTTTCCCATATGCACTTT
Associated Phenotype:
Not determined