Busch Lab

ZMP

pdcd8

Ensembl ID:
ENSDARG00000058088
ZFIN ID:
ZDB-GENE-030826-11
Description:
apoptosis-inducing factor 1, mitochondrial [Source:RefSeq peptide;Acc:NP_956396]
Human Orthologue:
AIFM1
Human Description:
apoptosis-inducing factor, mitochondrion-associated, 1 [Source:HGNC Symbol;Acc:8768]
Mouse Orthologue:
Aifm1
Mouse Description:
apoptosis-inducing factor, mitochondrion-associated 1 Gene [Source:MGI Symbol;Acc:MGI:1349419]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa1710 Essential Splice Site, Missense Confirmed mutation in F2 line Not yet available
sa33579 Nonsense Mutation detected in F1 DNA Not yet available
sa40408 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa1710
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000080882 None None 613 None 16
ENSDART00000080886 Essential Splice Site 241 750 6 19
ENSDART00000131889 Missense 242 750 6 19
ENSDART00000147513 None None 263 None 7
Genomic Location (Zv9):
Chromosome 5 (position 24347848)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 22060720
GRCz11 5 22564520
KASP Assay ID:
554-1656.1 (used for ordering genotyping assays)
KASP Sequence:
TGTAGTCAGCACCGAGCATGTTCCAGAGGCTTCATCTGTTTCTGAGAGTG[G/A]TAAGAGTCCAGGTTTCACTGGATGGGAATCAGTTCTGCAGATTAAACACG
Long Flanking Sequence:
TACTCATTCTGTGGAATTAGAACCTGTTGCTGAAGAACCAACTCTGATAGAACCCGCTGTTGAAGAATCTCCAGTAACAGAAGATATTGTGGAGTCACCTGAAGCTGTGGCAGAACCTATTGTAAAATCGTCTATTCCAGAACCCGCTGTGGAAATTGCAGTAACAGAACCTGTTGTCGAAGCCTCTGTTCCGGAATCCGTTATTGAATCCCCATTAATGGAACCCGTTGTTGAAGCCTCTGTTCAGGAACCCATTATTGAAGCTACAGCAACGGAAACTGTTGCAGAAGCTCCTGAAGTTATACAGAGTGAAGAGCCAATAGCTCCTGTGGTTGAGAGTGGTAAGCTTGACACATCTGAATGGAAATCCAGGATTGTTTTTTTATTTTGAAATTGAGGTTAACGTCTTTCCTCTCCTCTTACATTGGGATTATAAACAGAGCCTGTACCTGTAGTCAGCACCGAGCATGTTCCAGAGGCTTCATCTGTTTCTGAGAGTG[G/A]TAAGAGTCCAGGTTTCACTGGATGGGAATCAGTTCTGCAGATTAAACACGTAATCGATAAAGATAGTTATAAGTACTTCATACACATATGGACACCTTTATTTTTTGGTCATTTTTCTTTTTTCATTTAAGATCTTTTATTATTTTTGACTATATAAACCACATTGTCATCTCCTCTTTTGAAAGATGTCCTTTTCTCAGTCACTTCATTTCTTTGAAAGGTTGTTTTGTCATAGTGTGACTGTTGTAATGCTAATGACTAAAGCTAATGGTACAAGGTCACACACTAAAGGCCTTGAAATACATCAAATTAAATTGAAAAACAAACCTTTTTTGACAAATCAAGTTGTAAATACATTCAGCGTGGTCTGTGGTGATTATGGAATTGGTAGGCCCCACCTTCTTTTATTTTGAAATCGAGAGCTTGATACTTGAAACAACTTAATACATAATTTAATGCTTGTAGTAAGTACGTTGTTTCAGCAGTAGGTGTATAATATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33579
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000080882 Nonsense 334 613 10 16
ENSDART00000080886 Nonsense 471 750 13 19
ENSDART00000131889 Nonsense 471 750 13 19
ENSDART00000147513 None None 263 None 7
Genomic Location (Zv9):
Chromosome 5 (position 24338698)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 22051570
GRCz11 5 22555370
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGCTATTATTATTTTCTCTGTAGCTGCTGACCCTGGTTTAGAGGTGATG[C/T]AGCTCTTCCCAGAGAAGGGTAACATGGGAAAAGTGCTGCCTGAATACTTG
Long Flanking Sequence:
CCTGTCTACATGAATCTGTTTGTTCCAGAATGTAACCTTCATATGTTCTTTTTGGTAGATTGAAGATTTTAGATCTCTAGAGAAGATCTCCAGAGAGGTTAAGTCCATTACCATCATCGGTGGAGGTTTTCTCGGTAGCGAGCTTGCATGTGCCTTGGGTCGCAGATGTGAGTCCAAACACTCAGCTGTCACTCAGAGAAAAAGAAGGGGGGAAAAATCAGGTCATAGTGTTGAGATAGCAGGGGAAAGTGTGTGGGTATATATGTATATGTATGTATATGTGAATTAGTGAATAAATGTGTGTGTAATATATCAGTTTGATATAAACATTGTTAGTGCTTGCTTGTTAGTAGTAGGGTCATGACATACATGAGATTGTTATTGACGTGTATGTAATACTAGGTAATGTATTTATTCATATCATACAATAAAAAATATTAAAATGTTCTCATGCTATTATTATTTTCTCTGTAGCTGCTGACCCTGGTTTAGAGGTGATG[C/T]AGCTCTTCCCAGAGAAGGGTAACATGGGAAAAGTGCTGCCTGAATACTTGAGTAACTGGACCACTGAGAAAGTCCGGAAAGGTAAGAGAGTAAATAAATGATGTTTGTTTGAGAAGCCCGACAGCCTCAATAAATGTGGCATGTGTTTGTGTTCGGCAATGTTTGGATAACCTGTTTGAAACCTGTTGTACTTTTCAAATTCTGTTTAATGCAGGAGTTTGTTTGTTTATCCTTAATTGTCTGTATTAAATGTTGGTGATTTGGCGACAGCTAAGGTTTTTGTCTTTTCACAGAGGGTGTAAATGTAATTACGGATGCTGTAGTAAAAAATGTGACCTACAAAAATGACAAATTGGAGATCAAGCTAAAGGACGGACGACTGGTGAGTTTCCTTTTTCGTAAAACATTACTTTTGCTATACACAAAAGGGTAAACGTTTTATATAATAATATAGAGATAATATATAGAGATAATAAAGAGATGTATGGCATCAACATAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40408
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000080882 Nonsense 430 613 12 16
ENSDART00000080886 Nonsense 567 750 15 19
ENSDART00000131889 Nonsense 567 750 15 19
ENSDART00000147513 None None 263 None 7
Genomic Location (Zv9):
Chromosome 5 (position 24336738)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 22049610
GRCz11 5 22553410
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCTGGAAGTGGACTCTGATTTCGGAGGCTATCGGGTTAATGCTGAGCTC[C/T]AGGCTCGCTCTAACATCTGGGTGGTACGTAAGGCTATATTAGGGGGGGGT
Long Flanking Sequence:
CTATTTGGCAGGTGTGAGTGGAGGTGGTTGGAGCTAAAATCTGCAGAGCTGTGGCCCACCTGGAATTGAGTTTGAGACCCTTGCTTTAGTCCGAATAAAGTCATCAGAAATCTCTGTTTACATGGTAGACTCTTATTAAGAGTATTGTCTTATTAATACTAAAATTGGTGTGTTGGTGTCCATGAAAATGCAATCAGTGTTTTATTGAAAAGTTTGTGTAAACAGTTGAAGGCTCATATCAATGTTTTTTAATATTTATTCTTTTATGTTCACTTAGACGACTGATCCCTTAAGAAATGATTACTAGTCAAACAAGAAAACCTTTAGTTGAGGGCATCCCTATTAATAATGTAAATGCTTTTTTCTTTGTGTGTTTGATTTAGGTGAAAACAGACCACATAGTGGCAGCAGTTGGTTTGGAGCCCAGTGTGGAGCTTGCCAAATCAGCCGGGCTGGAAGTGGACTCTGATTTCGGAGGCTATCGGGTTAATGCTGAGCTC[C/T]AGGCTCGCTCTAACATCTGGGTGGTACGTAAGGCTATATTAGGGGGGGGTCTTATAATGTTACTGATATTAGCTCAATCCAGGAGACAGCATGAAGACAGATGGTTCTAAAAGAAAGAAATCCGTTTTTCTGAAAAGGTTTTAGCTGTAATAGATCTGATTGAATCAAGCACTTAAGTCAATATAATAGCAAATGTTTGTGTTTTAGGCAGGAGATGCTGCATGTTTCTATGACATTAAGCTGGGCCGCCGGCGTGTGGAGCATCATGATCACGCAGTGGTCAGTGGCAGACTGGCCGGTGAAAACATGACCGGAGCCAACAAACCCTACTGGCATCAGTCTATGTTCTGGTAAACACACCTTAAGCTCACTTTTTAACCCCTTCAGACCCTGCGTCCATTACAATGGATGCCACATGACATCCCATTTTTCTGAAATTTGGAACTTAATTCAGGTCTGAAGAGGTTAAAATAGATAATTCACTACAAAATTTTTAATTA
Associated Phenotype:
Not determined