Busch Lab

ZMP

ccne

Ensembl ID:
ENSDARG00000011133
ZFIN ID:
ZDB-GENE-980526-168
Description:
G1/S-specific cyclin-E1 [Source:UniProtKB/Swiss-Prot;Acc:P47794]
Human Orthologue:
CCNE1
Human Description:
cyclin E1 [Source:HGNC Symbol;Acc:1589]
Mouse Orthologue:
Ccne1
Mouse Description:
cyclin E1 Gene [Source:MGI Symbol;Acc:MGI:88316]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa17090 Nonsense Available for shipment Available now
sa25369 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa8454 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17090
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007883 Nonsense 191 410 7 12
ENSDART00000133570 None None 156 None 6
ENSDART00000136158 None None 156 None 5

The following transcripts of ENSDARG00000011133 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 47635020)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 45753131
GRCz11 7 46025497
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACTTTGATCGSTTCATGGCCACACAAGAAAATGTCCTGAAAACAACGCTA[C/T]AGCTTATAGGCATCTCCTGTCTCTTTATAGCTGCCAAAATGGAAGTAAGT
Long Flanking Sequence:
GGTTAGAAATCTGTGTTTTTGATACTACTGAAGTAAGTAAAAGTCAATGATTCATTTGAATTATTCAGCCTGACATGTTTACTGATCCAAAATATTTTAAATGTTTCTCAAAATAAAATATATTGTGTTCAAAGAGGGATATTCTTTTTATATGTTTACCCAGACATATCAAACAAATATATTTTAGAGCAGTAACCAAAATACCATGAAACCGTGATCTTTTTATCCAAGGTTATTATGCTGTCAAAATCTTATACCAGCCCATGCCTAGCTTGAACCCAAAGGACTCTTTCAGGAAACGAATAATCATGATTGGATTAGCATTTTTTTTATGGTATTTCATTTAATACTGAAGTGTTAAACGATTGACTAACTGACCTCTGTCTGCTGTCTTTCAGGTTTGTGAGGTGTACAAGTTACACAGAGAAACATTTTATTTGGGTCAGGACTACTTTGATCGGTTCATGGCCACACAAGAAAATGTCCTGAAAACAACGCTA[C/T]AGCTTATAGGCATCTCCTGTCTCTTTATAGCTGCCAAAATGGAAGTAAGTTTTACTTTCACATGCCCTTGCACTTCAACCTGAACTTTTGATAAGGGCTGTAATAGTGAGTGAATGAGTGTTGTTCTTGTTGTAGGGAAAATGCAGAATAATATAAACCTGTTTGCTTTTTTTTTTTTTTTTTTTTTTAAGGAAATTTACCCTCCTAAGGTGCATCAGTTTGCTTATGTTACTGATGGGGCCTGCACAGAGGATGACATTCTTAGCATGGAGATTATCATCATGAAGGTATATTGTCTTTATATCAGTTAACCTCAGTACCATGCCTAAACCTGCAGCTCCTGTGTAATATGATGAAATGGACTTGACTTTACTCCATTTGTTGTTTAGGAGTTAAACTGGAGTTTGAGTCCTTTAACCCCGGTTGCTTGGCTCAACATCTATATGCAGATGGCCTATCTAAAGGAGACTGCTGAGGTTCTCACGGCCCAGTACCCACAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25369
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007883 Essential Splice Site 237 410 8 12
ENSDART00000133570 None None 156 None 6
ENSDART00000136158 None None 156 None 5

The following transcripts of ENSDARG00000011133 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 47635309)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 45753420
GRCz11 7 46025786
KASP Assay ID:
554-7320.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCCTGCACAGAGGATGACATTCTTAGCATGGAGATTATCATCATGAAGG[T/C]ATATTGTCTTTATATCAGTTAACCTCAGTACCATGCCTAAACCTGCAGCT
Long Flanking Sequence:
TTTCAGGAAACGAATAATCATGATTGGATTAGCATTTTTTTTATGGTATTTCATTTAATACTGAAGTGTTAAACGATTGACTAACTGACCTCTGTCTGCTGTCTTTCAGGTTTGTGAGGTGTACAAGTTACACAGAGAAACATTTTATTTGGGTCAGGACTACTTTGATCGGTTCATGGCCACACAAGAAAATGTCCTGAAAACAACGCTACAGCTTATAGGCATCTCCTGTCTCTTTATAGCTGCCAAAATGGAAGTAAGTTTTACTTTCACATGCCCTTGCACTTCAACCTGAACTTTTGATAAGGGCTGTAATAGTGAGTGAATGAGTGTTGTTCTTGTTGTAGGGAAAATGCAGAATAATATAAACCTGTTTGCTTTTTTTTTTTTTTTTTTTTTTAAGGAAATTTACCCTCCTAAGGTGCATCAGTTTGCTTATGTTACTGATGGGGCCTGCACAGAGGATGACATTCTTAGCATGGAGATTATCATCATGAAGG[T/C]ATATTGTCTTTATATCAGTTAACCTCAGTACCATGCCTAAACCTGCAGCTCCTGTGTAATATGATGAAATGGACTTGACTTTACTCCATTTGTTGTTTAGGAGTTAAACTGGAGTTTGAGTCCTTTAACCCCGGTTGCTTGGCTCAACATCTATATGCAGATGGCCTATCTAAAGGAGACTGCTGAGGTTCTCACGGCCCAGTACCCACAGGCTACATTTGTGCAGATTGCAGAGGTAGGATGGCACAATTAATTGGATTAAATTCGCAATATGGTGTGCGACTATATTTACTGAATAAGGATGCGATTCAATTAAATTTATATTCTGCACATGTCGTATCCTGCCAGTGGCCTGGCAGTGTTCTGTTTTCTTTGGCTTTCTTAAAGCAGTCACAAAACATAATTGGACCCTATGAATTTAGGGTATTGTACCCAAAACAAATCTCACCAATTCTGTTGTGGGTCAACTTTTTATATGGACAGCAAATGAAGCAATTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8454
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000007883 Nonsense 255 410 9 12
ENSDART00000133570 None None 156 None 6
ENSDART00000136158 None None 156 None 5

The following transcripts of ENSDARG00000011133 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 47635463)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 45753574
GRCz11 7 46025940
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTAAACTGGAGTTTGAGTCCTTTAACCCCGGTTGCTTGGCTCAACATCTA[T/A]ATGCAGATGGCCTATCTAAAGGAGACTGCTGAGGTTCTCACGGCCCAGTA
Long Flanking Sequence:
CAGGACTACTTTGATCGGTTCATGGCCACACAAGAAAATGTCCTGAAAACAACGCTACAGCTTATAGGCATCTCCTGTCTCTTTATAGCTGCCAAAATGGAAGTAAGTTTTACTTTCACATGCCCTTGCACTTCAACCTGAACTTTTGATAAGGGCTGTAATAGTGAGTGAATGAGTGTTGTTCTTGTTGTAGGGAAAATGCAGAATAATATAAACCTGTTTGCTTTTTTTTTTTTTTTTTTTTTTAAGGAAATTTACCCTCCTAAGGTGCATCAGTTTGCTTATGTTACTGATGGGGCCTGCACAGAGGATGACATTCTTAGCATGGAGATTATCATCATGAAGGTATATTGTCTTTATATCAGTTAACCTCAGTACCATGCCTAAACCTGCAGCTCCTGTGTAATATGATGAAATGGACTTGACTTTACTCCATTTGTTGTTTAGGAGTTAAACTGGAGTTTGAGTCCTTTAACCCCGGTTGCTTGGCTCAACATCTA[T/A]ATGCAGATGGCCTATCTAAAGGAGACTGCTGAGGTTCTCACGGCCCAGTACCCACAGGCTACATTTGTGCAGATTGCAGAGGTAGGATGGCACAATTAATTGGATTAAATTCGCAATATGGTGTGCGACTATATTTACTGAATAAGGATGCGATTCAATTAAATTTATATTCTGCACATGTCGTATCCTGCCAGTGGCCTGGCAGTGTTCTGTTTTCTTTGGCTTTCTTAAAGCAGTCACAAAACATAATTGGACCCTATGAATTTAGGGTATTGTACCCAAAACAAATCTCACCAATTCTGTTGTGGGTCAACTTTTTATATGGACAGCAAATGAAGCAATTTTGAAAAACACTGTATAGTTTTAGAGGTTTGGAGGAAAATGTATGAATGACATAATTTAGATCTTTGGGGGAACTGTCCCTTTAAAAACCCTTAATGCACGTTAATACAGACATTTTCACTACAAGGTACTAGATATAATTAAGCAAAACCATGCTT
Associated Phenotype:
Not determined