ZMP

map2k4

Ensembl ID:

ENSDARG00000063583

ZFIN IDs:

ZDB-GENE-060512-98, ZDB-GENE-060512-98

Description:

mitogen-activated protein kinase kinase 4 [Source:RefSeq peptide;Acc:NP_991299]

Human Orthologue:

MAP2K4

Human Description:

mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:6844]

Mouse Orthologue:

Map2k4

Mouse Description:

mitogen-activated protein kinase kinase 4 Gene [Source:MGI Symbol;Acc:MGI:1346869]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa1709	Essential Splice Site	Confirmed mutation in F2 line	Not yet available

Mutation Details

Allele Name:

sa1709

Status:

Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000058834	Essential Splice Site	153	229	7	9
ENSDART00000093037	Essential Splice Site	276	404	8	13
ENSDART00000130761	Essential Splice Site	276	404	8	12

Genomic Location (Zv9):

Chromosome 3 (position 11503878)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	10635853
GRCz11	3	10602396

KASP Assay ID:

554-1655.1 (used for ordering genotyping assays)

KASP Sequence:

TGACTCCATCGCCAAAACCAGAGACGCAGGCTGCAGACCGTATATGGCAG[T/A]AAGTTTGTTTATTCGCTTATACTGTATATACAGTACGCACTACTGTTCAC

Long Flanking Sequence:

TTGAAGAGTTCAGACACAAAAAACTTTAAGTGCTGTCTGAAATTTCAGTTGAAAATGAAATTATTTTTCCCCCTCCTTTGTTTATGTTCAGTTATTTCAATATAAAGACCAGAAAAATAACATATTTTTGCCATAAAGGTGTAATTACTGAACTTACAGCAGTCTGAAAAAAATGCTCATTTTGGAAGAGAATTTTTGGATGCATTTAGAGATTTTTGCATCTGAACTCTTCATTTATTGGTGTAATTGTGAGCCCTTTGGCTTTTCATTTAAAGCGAGGCTCAGTTTGTGGATTTCTTGTTTGTAACTGGTTAGATGTGAAGGCAGTGCTGTTTTCCTCTGACTGAAGCTCTTTTTGGTCCTTTCTGCAGACATAAAGCCATCAAATATCCTCCTGGACAGGAAAGGCAACATTAAACTGTGTGATTTTGGCATCAGTGGGCAGCTGGTTGACTCCATCGCCAAAACCAGAGACGCAGGCTGCAGACCGTATATGGCAG[T/A]AAGTTTGTTTATTCGCTTATACTGTATATACAGTACGCACTACTGTTCACGTAGTTGTGGTTTGGATGATTTCTGTAATGTTTTTTTTTTAAGTTTCTTTGCTTTCCAAAGCTGAATTTATTTGATGGAAAATACAGTTGGAAAAGCAATATTGTAATATTTTTTTAAAATGTAATTTATTTTCTTTATGCAAAGCTGATTTTTTTTTTTAGTGCCCTTCAGGTTCCGTAATGATCCTTCAGAAATCAATATAATGTATACAGCTACTGTAAACAAGGGGACACTAATTAAAAATCCTCAGTGTCTCTGGATTTACCTTTATATTCAATTCAATTCATCTTTATTTCTATAGCACTTTTACTATGTAGAGTGTGTCAATTATAGTTTTGTGCAAGTACATTATTTTCTATTATTATTTTATTCTGTAAAGTACTACTGACATTTTTTTAATTAAAAAGAAATATTGTATTTTGTAAACAACATCAACATCTTAATTTTCA

Associated Phenotype:

Not determined