ZMP

si:zfos-367g9.1

Ensembl ID:

ENSDARG00000074816

ZFIN IDs:

ZDB-GENE-030616-172, ZDB-GENE-030616-172, ZDB-GENE-030616-98, ZDB-GENE-030616-98, ZDB-GENE-091204-401

Description:

Novel protein similar to MHC class II alpha chain [Source:UniProtKB/TrEMBL;Acc:Q8MGS6]

Human Orthologues:

HLA-DMA, HLA-DMB, HLA-DOA, HLA-DPA1, HLA-DQA1, HLA-DQA2, HLA-DRA, XXbac-BPG181M17.5

Human Descriptions:

Major histocompatibility complex, class II, DM beta [Source:UniProtKB/TrEMBL;Acc:A2AAT6]
major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:4934]
major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:4935]
major histocompatibility complex, class II, DO alpha [Source:HGNC Symbol;Acc:4936]
major histocompatibility complex, class II, DP alpha 1 [Source:HGNC Symbol;Acc:4938]
major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:4942]
major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:4943]
major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:4947]

Mouse Orthologues:

H2-Aa, H2-DMa, H2-DMb1, H2-DMb2, H2-Oa

Mouse Descriptions:

histocompatibility 2, O region alpha locus Gene [Source:MGI Symbol;Acc:MGI:95924]
histocompatibility 2, class II antigen A, alpha Gene [Source:MGI Symbol;Acc:MGI:95895]
histocompatibility 2, class II, locus DMa Gene [Source:MGI Symbol;Acc:MGI:95921]
histocompatibility 2, class II, locus Mb1 Gene [Source:MGI Symbol;Acc:MGI:95922]
histocompatibility 2, class II, locus Mb2 Gene [Source:MGI Symbol;Acc:MGI:95923]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa17022	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa17022

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
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Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000075833	Essential Splice Site	197	236	4	4
ENSDART00000109439	Essential Splice Site	197	236	4	4

Genomic Location (Zv9):

Chromosome 8 (position 37474037)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	36330084
GRCz11	8	36362518

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

WTCTGATATTYATTTATYTTYAAATATYTAAAGCATGACATTGTTTTCCA[G/A]ATGTTGATGTTGTCCTCCCAAACTWTGGTCCATCAGTGTTCTGTGGAGTG

Long Flanking Sequence:

AATGGGACTGAGAACTTGGGTAGAGATGGAAGGGCATGCGCTGCATAAAACATAAGCAGGACAAGTTGGCAGTTTGCTCCGCTCTGCCGACTCCGGATTAATAAAGGGACTAAGCCTAAAAGAAAATGAATAAACTTGGGTAGACGTTTGACACTAATAAAGTCTAACAGATTAATTATAAGTGAAGCTGCTGATGTTCTTTGTAGAGATCTCTGCTGCGATTTTGAGAGATTTAATGTTTTAGTTGATTTCATCTAAGGCTTTGTCAAAGTCCAAAATGGACATCATAAAAGCGTTCATTCTGCACCCTTAGAGGATGTAATTTCTGCGTCTAATTGTCCAAAAAAACATCTAAAAGATTTCATTTGAACACGATTGTTCTGTAGGACACATCACGAGTCCAGCTGTTTCATTTGTTATAAAACATTCTTATTCTAATTAGCTTCATGCATCTGATATTTATTTATCTTCAAATATCTAAAGCATGACATTGTTTTCCA[G/A]ATGTTGATGTTGTCCTCCCAAACTTTGGTCCATCAGTGTTCTGTGGAGTGGGTCTGACTATTGGACTCTTGAGTGTCGCTATCGAAACTTTCTTTCTTTTTAAAAGAAAAAAGAGCAACTGACAATGGATCAATCGAAGCAAACTTCAGTAATGATCTTTAACTGTATTTCAACCTAATATTCCACTAAACTTTCATTCTTCAAGTACCATAGTTAATAATATATTTATAAAAATGTGTACACATAAATCTGGAATAAAACTTCACTATCGTTGTATTGACTCATAATTCAAACATTGTTTTAAAAAGTATTTGATGTTTTTTATTTACTAAAAATAATTTGATGCATTTTAAAGCAAAATGCCTTTAAATAGTTCTTAAAGGAACACATTTTACACTGTTAAGGTACAAAGTGTCTTGTCACTTTAGTGCTACCTTCATGAACCAGATTAGATTTTTTTTGATGAAGGTACAATATTGTATCTGCAGGTTTTAAAAACT

Associated Phenotype:

Not determined