Busch Lab

ZMP

NPR1 (2 of 2)

Ensembl ID:
ENSDARG00000018750
Description:
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) [Source:HGN
Human Orthologue:
NPR1
Human Description:
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) [Source:HGN
Mouse Orthologue:
Npr1
Mouse Description:
natriuretic peptide receptor 1 Gene [Source:MGI Symbol;Acc:MGI:97371]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa36166 Nonsense Mutation detected in F1 DNA Not yet available
sa16937 Nonsense Available for shipment Available now
sa12864 Nonsense Available for shipment Available now
sa42742 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa44853 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa36166
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018213 Nonsense 383 1070 4 21
Genomic Location (Zv9):
Chromosome 16 (position 31171408)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 29008597
GRCz11 16 28943220
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGATGCTGTACTGCCATGCTTTAAATGAGAGCCTTTCAGACAGCCATGAA[C/T]GACCTTCAGGAGAGTCTGTCAGCAAACGAATGTGGAACCGGACCTATTAT
Long Flanking Sequence:
AAATTAAATGTGATTTTACTCAAAACAAGAACAAACCTGCCAATGCAGTTAGAAAAATAATCTTCTTTACTTTTGAGTTTTCTGACCACATTGTCATGTTCTGTACTTGTTTTTGTTTTAAAACAAACTCATTTATATTTTAACCAGTTTTTTCAGACAGCAAGACTAAAATAAAAATATAAAATTATTAATTAACAATAAAGTAGTTTTGCTTCTCAAATAAATGTGTGTTGATTTCAGAATGTTTAGATATGTGTGTAGAATGAACAATCATTTTGCCGTCATTTTTATTTATTTTGCTTCTGTAATTATATCTTGATTTAAGAACATTTAGATTATTGTACTATAATACTGAGATAAAACATACATTTTCATTTTCCTGTGTTTTAACTTGTTTGTGTATTTGATTCTTTCAGATGAACATCATCTCTGGGGGTTTCTATGATGGTCTGATGCTGTACTGCCATGCTTTAAATGAGAGCCTTTCAGACAGCCATGAA[C/T]GACCTTCAGGAGAGTCTGTCAGCAAACGAATGTGGAACCGGACCTATTATGGTGAGTACATGATCCAAATGAAATGGATCATTGTCAAATGTGACATTACATTAATATGTTATACAGAGACTTTTTTTATCTTAAAACCTTGACTTAATGGCCCATTTTAACTACAGTATGTGCAAATTTATGGGAGGGATTGATTTAATGTTTGGACCCTCCTGTAGAAAGTCAAAACTACGTGTATGGTGGTCTGGAAAATGTTTTCAGTGATCTGTTAGTGAGATGATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAAAGTTAATATAAATATGAATTTGTATTTTATTCACAATACTATTAAACAATACTATTATAGTTCACAATATTATTAAATATTACAATTGTAACAACATCAACAGCAGCGCACGTGCACAATATGCAGCTGATTCTGTGGTTGACGAGCGACATAAAAAGCGCAGCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16937
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018213 Nonsense 398 1070 4 21
ENSDART00000018213 Nonsense 398 1070 4 21
Genomic Location (Zv9):
Chromosome 16 (position 31171455)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 29008644
GRCz11 16 28943267
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAACGACCTTCAGGAGAGTCTRTCAGCAAACGAATGTGGAACCGGACCTA[T/G]TATGGTGAGTACATGATCCAAATRAAATRGATCATTGTCAAATGTGACWT
Long Flanking Sequence:
GTTAGAAAAATAATCTTCTTTACTTTTGAGTTTTCTGACCACATTGTCATGTTCTGTACTTGTTTTTGTTTTAAAACAAACTCATTTATATTTTAACCAGTTTTTTCAGACAGCAAGACTAAAATAAAAATATAAAATTATTAATTAACAATAAAGTAGTTTTGCTTCTCAAATAAATGTGTGTTGATTTCAGAATGTTTAGATATGTGTGTAGAATGAACAATCATTTTGCCGTCATTTTTATTTATTTTGCTTCTGTAATTATATCTTGATTTAAGAACATTTAGATTATTGTACTATAATACTGAGATAAAACATACATTTTCATTTTCCTGTGTTTTAACTTGTTTGTGTATTTGATTCTTTCAGATGAACATCATCTCTGGGGGTTTCTATGATGGTCTGATGCTGTACTGCCATGCTTTAAATGAGAGCCTTTCAGACAGCCATGAACGACCTTCAGGAGAGTCTGTCAGCAAACGAATGTGGAACCGGACCTA[T/G]TATGGTGAGTACATGATCCAAATGAAATGGATCATTGTCAAATGTGACATTACATTAATATGTTATACAGAGACTTTTTTTATCTTAAAACCTTGACTTAATGGCCCATTTTAACTACAGTATGTGCAAATTTATGGGAGGGATTGATTTAATGTTTGGACCCTCCTGTAGAAAGTCAAAACTACGTGTATGGTGGTCTGGAAAATGTTTTCAGTGATCTGTTAGTGAGATGATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAAAGTTAATATAAATATGAATTTGTATTTTATTCACAATACTATTAAACAATACTATTATAGTTCACAATATTATTAAATATTACAATTGTAACAACATCAACAGCAGCGCACGTGCACAATATGCAGCTGATTCTGTGGTTGACGAGCGACATAAAAAGCGCAGCACCCTTCTTTTTTTTCTTGTTAGAAAAAAGGCAATGTGGCAAATGAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12864
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018213 Nonsense 398 1070 4 21
ENSDART00000018213 Nonsense 398 1070 4 21
Genomic Location (Zv9):
Chromosome 16 (position 31171455)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 29008644
GRCz11 16 28943267
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAACGACCTTCAGGAGAGTCTRTCAGCAAACGAATGTGGAACCGGACCTA[T/G]TATGGTGAGTACATGATCCAAATRAAATRGATCATTGTCAAATGTGACWT
Long Flanking Sequence:
GTTAGAAAAATAATCTTCTTTACTTTTGAGTTTTCTGACCACATTGTCATGTTCTGTACTTGTTTTTGTTTTAAAACAAACTCATTTATATTTTAACCAGTTTTTTCAGACAGCAAGACTAAAATAAAAATATAAAATTATTAATTAACAATAAAGTAGTTTTGCTTCTCAAATAAATGTGTGTTGATTTCAGAATGTTTAGATATGTGTGTAGAATGAACAATCATTTTGCCGTCATTTTTATTTATTTTGCTTCTGTAATTATATCTTGATTTAAGAACATTTAGATTATTGTACTATAATACTGAGATAAAACATACATTTTCATTTTCCTGTGTTTTAACTTGTTTGTGTATTTGATTCTTTCAGATGAACATCATCTCTGGGGGTTTCTATGATGGTCTGATGCTGTACTGCCATGCTTTAAATGAGAGCCTTTCAGACAGCCATGAACGACCTTCAGGAGAGTCTGTCAGCAAACGAATGTGGAACCGGACCTA[T/G]TATGGTGAGTACATGATCCAAATGAAATGGATCATTGTCAAATGTGACATTACATTAATATGTTATACAGAGACTTTTTTTATCTTAAAACCTTGACTTAATGGCCCATTTTAACTACAGTATGTGCAAATTTATGGGAGGGATTGATTTAATGTTTGGACCCTCCTGTAGAAAGTCAAAACTACGTGTATGGTGGTCTGGAAAATGTTTTCAGTGATCTGTTAGTGAGATGATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAATAAAGTTAATATAAATATGAATTTGTATTTTATTCACAATACTATTAAACAATACTATTATAGTTCACAATATTATTAAATATTACAATTGTAACAACATCAACAGCAGCGCACGTGCACAATATGCAGCTGATTCTGTGGTTGACGAGCGACATAAAAAGCGCAGCACCCTTCTTTTTTTTCTTGTTAGAAAAAAGGCAATGTGGCAAATGAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42742
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018213 Essential Splice Site 655 1070 12 21
Genomic Location (Zv9):
Chromosome 16 (position 31199143)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 29036332
GRCz11 16 28970955
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTACACTAGATTGGATGTTCAAATACTCATTAATCAGCGACATAGTAAAG[G/A]TAGAAACCCCTTTCTGTATTTTGTTAATGATGAAATTCACGTTAAAGGCA
Long Flanking Sequence:
TGTTGAAAGCTCAGGTATGTTTAAAGTCACAGTCACAATTGTAAGAAATGTGTTCAAATTGTAAGATGTAAACTTAGAATTGCAAAAAATGCATTCGAATATGTCTCAAATCTGAATTGTACAATTTATTTTGTAGGACTTTTTTCCATATGAACAACTTTGCCAAAGAACTTGCCTAGTGTGTGTTTGGCAGAAGTATTTAGACTGTTTACATTCATTTAGATGGAATCAGGCATTCTTGATATTTTGTAGAATAATATAGAAAGTACATTTTTATTTCTCAAAAAATGTGTCCCCAACTTAAGTTTAAATGTACAAAAAATACACAGACACACACAAAAAGAATTTAATATTTGCATGCTTTAAAAATCATTTAGCAATTTAGCACTGAAATTGTACATCTCCGAATTTCTGCATCTTTTTTACAGAATATTTTGGAGAACGACAGCATTACACTAGATTGGATGTTCAAATACTCATTAATCAGCGACATAGTAAAG[G/A]TAGAAACCCCTTTCTGTATTTTGTTAATGATGAAATTCACGTTAAAGGCATAGTTCACCCAAAATTTCAAAATCTGTCATCATTTTCTCACCCTCCACTTGCTCCAAACTTTCATGAATTTCTTTTTTCTATTCAACAAAAAAGGACAAAATATGAAGAACATAATATATCACATCAATTCTTTTTATTCTACCATGAATTTCAATGGCTGCCATTTTCAACATTCTTCAAAATCCTTTTTTGGATGACAGAAGAAAGAAGCTCATAAAGCTTTGGAATCACTTGAAATTGATTAGACGTTAAATAAATGTTTATTTTTGGGTGAACCATCTCTTTAAATGTTTATTTTCCATTCTCCCTCATTGCACTGCATCCTTATCCTCCTGCTTTCCTTCATACTGCCCAATCTGTCTCTCCCCTCAGGGCATGGCTTTCCTTCATAACAGTGTGATTGTATCCCATGGCAACCTGAAGTCTTCCAACTGTGTGGTTGACAATCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44853
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018213 Essential Splice Site 989 1070 19 21
Genomic Location (Zv9):
Chromosome 16 (position 31215039)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 29052228
GRCz11 16 28986851
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGCCACCGACCCGATGAGCAACTCAAATTACGAATCGGCATTCACAGTGG[T/C]GAGAATGAGCATTTTAAACAGTTTTTTTGACACTAACAGGGAATTTTCTT
Long Flanking Sequence:
GTGATTTTTTCTTTTGTCCTGTGCTTTGTGCTGAAGTAAATCTCCACCTGCTATACTAGTGCTAAACAATGTCTAAAATAATCAGTAAATATTAAAACTTGAAGCCAAGGGTGTTTACACAATGGTGTTTACATCCAAGAACTGAAAACATTTAATGTATTTTGGCTGTTTTCTATAAAGTGCACGAGTTTGAATTTGATGAATTATCTTCTCTACCTATGCATATTACAGTATGTGTTCAGTCTATAGGCATGTTTAATACAACTTTGACAGACTACATATATATATATTTCATATATCATTTTTGTTTTATTGTTCCTTTAGGTGGAGACAATAGGCGATGCTTACATGGTAGTTTCAGGACTGCCGGTACGAAACGGCAAACTGCATGGTCGTGAGATTGCACGGATGTCCCTCGCTCTGTTGGAGGCTGTCAAAACATTTAAGATTCGCCACCGACCCGATGAGCAACTCAAATTACGAATCGGCATTCACAGTGG[T/C]GAGAATGAGCATTTTAAACAGTTTTTTTGACACTAACAGGGAATTTTCTTGTATTGAACTATGTTTATCTAACATAATACTAAACATTACTAAATACTAAATGCTAATAAATATTCATATTTATTAATATTACAAAATATTAGTAATAAAATTGTTCTAACATACTAAACCTGGTTTTAGCATATGAAGTTTTGAGTATTGAGAATTGTGTGTTTTGTTTGTGTCTGTGTGTATGTTCCAGGCCCTGTATGTGCAGGTGTAGTTGGGCTGAAGATGCCTCGGTATTGTCTTTTCGGAGATACTGTAAACACATCTTCTCGTATGGAGTCGAATGGAGAACGTAAGAGAAAAAATTATCTCTATCCCACCAAACACTTTAAAACTTAAAGGTCCCATGAAGTGCTGTGAAATGTGCATTTTTTATTAGCTGTTTGACGTAATCTCAACTGAAAAATTATGGGAGAGTGGGACATAAAATAGCTCCTCAGCTTTTTAAAAAC
Associated Phenotype:
Not determined