ZMP
stat3
Ensembl ID:
ZFIN ID:
Description:
signal transducer and activator of transcription 3 [Source:RefSeq peptide;Acc:NP_571554]
Human Orthologue:
STAT3
Human Description:
signal transducer and activator of transcription 3 (acute-phase response factor) [Source:HGNC Symbol
Mouse Orthologue:
Stat3
Mouse Description:
signal transducer and activator of transcription 3 Gene [Source:MGI Symbol;Acc:MGI:103038]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa15744 | Nonsense | Available for shipment | Available now |
| sa938 | Essential Splice Site | F2 line generated | Not yet available |
| sa10162 | Essential Splice Site | Available for shipment | Available now |
| sa12185 | Essential Splice Site | Available for shipment | Available now |
| sa16856 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa15744
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022006 | Nonsense | 73 | 414 | 3 | 13 |
| ENSDART00000080854 | Nonsense | 73 | 786 | 3 | 23 |
| ENSDART00000104519 | Nonsense | 73 | 806 | 3 | 24 |
Genomic Location (Zv9):
Chromosome 3 (position 16690112)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 16920331 |
| GRCz11 | 3 | 17070131 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TYTTCCACAACCTGCTGGGCGAGATCGATCAGCAGTACAGCCGCTTCCTG[C/T]AGGAGAACAACGWCCTGTACCAGCACAACCTGCGGCGCATCAAGCAGCAC
Long Flanking Sequence:
CCAGTACACAAACCTCTGATTATGTAATGATTACAAACCATTTATCTGCTAATTAAATTGTTTGTGTGCTGTAAGAAAATGCTGGGTTCCACACAATCAATTTGTCTCAGGACAACGTGAAGGAATTAACTTAATAGTTTTTACAAATTTAAGTGGATTGAACATAAAACAATGAACTTTTCCTAAAAAAACCTCAAGAATTGTATTATTTAAGCTCATTTTAAGTAAGTAGTTTGAACAAGCAGAAAATGTAATATTTTAAGTGTCTGAACTTGCTTTTAAAGATGCTTACTATTTTCCCTTTTACTGAAACACATGGATGCTTATTTTTATCGACAATACCTCCTCTGATTATCTCTAATGCATGTATGGAATGAAGAAAACTACATTATTATGCACATGTCCTCCACAGGGCGTATGCGGCCAACAAGGAGTCTCACGCCACGCTGGTCTTCCACAACCTGCTGGGCGAGATCGATCAGCAGTACAGCCGCTTCCTG[C/T]AGGAGAACAACGTCCTGTACCAGCACAACCTGCGGCGCATCAAGCAGCACCTGCAGAGCAAGTATCTGGAGAAGCCCATGGAGATTGCCCGCATCGTGGCCCGCTGCCTGTGGGAAGAGCAGCGTCTACTGCAGACGGCCACCACTGCACAGCAGGTACATCCACAAACACACATTTGATTATTTTATTTGGAATGACTAATGCTGGGTTAAGGCAGCACAGCATTCAAATAATCACAAAGAGACAATTATGTTTCATTGTACAAGCAATGTGCAGAGATAACGTGACTTAATATCTTTTACAGGACATTAATAATAAATACGTGTCAAATGTGCAAAAATATAATATCCACATACAAGGAAAGAGATGTCATCGTCTTTTCCAAGCATGCAAGCTGCAGTTTTATTTATCTTTCACCGTTCTTGTTGGCATTTAAGAGTGGTGTAGATGTAAAATTGATTGTTTATTCACCATGTTGCCTGAGATGCATGTGCACGCAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa938
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022006 | Essential Splice Site | 381 | 414 | 12 | 13 |
| ENSDART00000080854 | Essential Splice Site | 381 | 786 | 12 | 23 |
| ENSDART00000104519 | Essential Splice Site | 381 | 806 | 12 | 24 |
Genomic Location (Zv9):
Chromosome 3 (position 16701207)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 16931426 |
| GRCz11 | 3 | 17081226 |
KASP Assay ID:
554-0843.1 (used for ordering genotyping assays)
KASP Sequence:
TATCTATAAAAGTTGCTGCATTACTTTAGCCCTCTGCTTTTTTTTCTTCA[G/A]TTCACGCAAGTTCAACATCCTTGGCACTAACACTAAGGTGATGAACATGG
Long Flanking Sequence:
GTAGGTCTACTGTTGGTTAAAATGAAACACTTTGTATAGACTTGGAATGGTGGACCTTATTAGGCATAAATATGTCCTGGTCATTAATGCACAGTAAAGTGATGACATCAGAATACAACTATTCATAATTCTGAAGTTGAATTATTGTGTTGAAATTGTGGTTCTCATTTTAGCCAGAATTGTGCAGCCCTAATACTTATAATAATAATAAAATTAATAATCAATAAATTGAAATTTCATTTTGTAAAGTGCCTAAGAAGGTCTGCACTCAATAATTAAGTATATCACAGTAGAAAAGAAAAAGCAACGGGATGAAACGTTTGTTGATCTTCTGTGGTACTTTTCATTTAAAGACATTTGGCCACAGCACCAGATTAGAGGAGTGCTTAGATTTTCTTTTGACTAGGTGTTATTTTTTTAAAAATCCAGTGAAATTGTGTTTCTTGCTTGTATCTATAAAAGTTGCTGCATTACTTTAGCCCTCTGCTTTTTTTTCTTCA[G/A]TTCACGCAAGTTCAACATCCTTGGCACTAACACTAAGGTGATGAACATGGAGGAATCCAACAATGGCAGCCTGTCAGCAGAGTTCAAACATCTGGTAAGCTCAGCCAGTATGCTAGTATGTTTTTCAAAGCTCCAAACCATGTGTTTTCTGGAGTTGTTTGTGTTTCTTTAACTGGGAGCACTGTTATGCTTCTCTGAACAGAAAGGAAAACTCCCTCAACATAATCAAATATATTTGTGCACATCAGTTTCAGCATTGAATATATTTAATTTCGAGCAAGATTTTTGCTTTTAGTAAAGAAAGATATACACTTTATTAGTAGCCACAATTACTGTTGAAGTCAAAAATTGTGTAAGAAACTATCAAATTTTTTTTACACTAGCTTAGTTCATCATAGGCTACAAATATGCTTCAAAATTACTGGGTATATATAATAAATCACAGTTTTTTTATATTCGAATTCCTAAATTCATAGTCACTGTTTCATACTCTGTAACAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa10162
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022006 | None | None | 414 | None | 13 |
| ENSDART00000080854 | Essential Splice Site | 552 | 786 | 17 | 23 |
| ENSDART00000104519 | Essential Splice Site | 552 | 806 | 17 | 24 |
Genomic Location (Zv9):
Chromosome 3 (position 16710533)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 16940752 |
| GRCz11 | 3 | 17090552 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGTGTAAACTACWCCGGTTGCCAGATCACATGGGCTAAGTTCTGCAAAG[T/A]ATGTTTCTGCAATAATCACTTGTTCCTTGTTCTTTATAATTTTAGAGCAA
Long Flanking Sequence:
TTTGAAGGAGATAAGTATTTTGTGAGAAGCCAAAAATGGCAAGATCGGCATCTGGTAGAAAAGATCTGCTATAAACCTTGTGTATCCAGTCAAATATGTTGGTGCAGAATCTATTCAGGAAGGGACAGAGCCAAAAGGCACGAGCAACCGTGTCCTCTGCTGTATTATATGTATCACTTGTTGGTGAGACAGAAGGAAAGATTTTATGTAGCTTGGCTTTAGTGTACTATGTATGTCCATGTGTCTCTAGAGATTTCGATTCTTAGGCAACTTTAAATCTCAGAGGATACTGTAACACAACTTTCAGATAAACACACACACATTTAGAAATAAGATGCCTAGAGTCAACTTGTGATTTTAACTTGCATTATTTATCTATAATAAAATTAACATTAAATGTATGAATCAGTGTCTAATTGTGTGTGTGTGTGTGTGTTTTTGCGCAGGTCCCTGTGTAAACTACTCCGGTTGCCAGATCACATGGGCTAAGTTCTGCAAAG[T/A]ATGTTTCTGCAATAATCACTTGTTCCTTGTTCTTTATAATTTTAGAGCAAATCATTTAGTTTCTATCAAGTTATTCTAAACGTTGTTTCTTCTGCTTTTGCTTTGTGTCTCGCAGGAAAACATGGCAGGAAAAGGTTTCTCATTCTGGGTGTGGCTGGACAACATTATTGACCTGGTGAAGAAATATATTTTGGCCTTATGGAATGAAGGGTGAGAGCTCATGCTGCACTGCGCTGTGTGTGCATTCATGCGGTGTTTATAGTTCATTGCATCAGCTGCTGCATGGGTGGGTGCATCAACCTCTTGTTTGTGTGTGTGTGTGTGTGTGTGTCAGGTATATTATGGGTTTCATCAGTAAAGAAAGAGAGAGAGCAATCCTGAGTCCAAAGCCTCCTGGGACGTTTCTGCTGCGCTTCAGTGAAAGCAGCAAAGAGGGAGGAATCACATTCACGTGGGTCGAGAAGGACATCAATGGTGAATGCATTTCTGTGCACATGATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa12185
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022006 | None | None | 414 | None | 13 |
| ENSDART00000080854 | Essential Splice Site | 718 | 786 | 21 | 23 |
| ENSDART00000104519 | Essential Splice Site | 718 | 806 | 21 | 24 |
| ENSDART00000022006 | None | None | 414 | None | 13 |
| ENSDART00000080854 | Essential Splice Site | 718 | 786 | 21 | 23 |
| ENSDART00000104519 | Essential Splice Site | 718 | 806 | 21 | 24 |
Genomic Location (Zv9):
Chromosome 3 (position 16714800)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 16945019 |
| GRCz11 | 3 | 17094819 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTCAGTAACTCAACCCTACCTGAAGACCAAGTTCATCTGTGTCACCCC[G/A]TAAGTAGCACTTATTTCTTCCTCTCWGAGTGTGTGTGTGTRTRTGTGTGT
Long Flanking Sequence:
TTTGTAATCATCTCAAAAATCATATGGACCTGTGTTAATTTCATCAACAAAAATATTTGACGATGACCTTTTATTCCCCGACAAAGACAGGATGACTCAGATGTCATTAGATACTAAAAGTGACTACATCAATATGCAGTATTGTTGACGAGAAGACTAAAATGTAGTCAGAAGGCTAAGAACAGACCAAAAACCTCTGTTTTCATCAAGGTTAATTCTTTGAATATTTACTATATTATGCTGTTTATTCATTAGATGAGGTGATCAAAACGTGTGCATTTATAGTTTCTGTTTAGTTCAACTTAGACTGTTTCATGACTTTTTTATGATTTTTTTTAAGTTGTGTTTTTTTTGTGTGTAATTTTATTAATTTTTGTATATTTTCCTTTTTATGCCAGCAGCTCAATTTAAAGTCCGAAACTCATTTGACCACATCCATTTCTTGCTTTTTTTTCAGTAACTCAACCCTACCTGAAGACCAAGTTCATCTGTGTCACCCC[G/A]TAAGTAGCACTTATTTCTTCCTCTCTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTATGTGTGTGTTTGAGTTTGCTGGAGTCTCTCTGTCCTCTTGTAAACTCTGAAATCTCTGGTGACTCTTCAGGCAGGAGCATATGCCTCCACTCAGTTCACTTTACACCATGGATCAGGGATGTAGCCACTACTGACTCTCCTGCACGGACCCTTCACATCACATCATCCTAAAAAAAGCACAATCTTGCACAGGAAGAGAGAGAGAGATGCTTTAAAACATAACACACACACACACACACACACACACACACACACACACACACACACACAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16856
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000022006 | None | None | 414 | None | 13 |
| ENSDART00000080854 | Essential Splice Site | 718 | 786 | 21 | 23 |
| ENSDART00000104519 | Essential Splice Site | 718 | 806 | 21 | 24 |
| ENSDART00000022006 | None | None | 414 | None | 13 |
| ENSDART00000080854 | Essential Splice Site | 718 | 786 | 21 | 23 |
| ENSDART00000104519 | Essential Splice Site | 718 | 806 | 21 | 24 |
Genomic Location (Zv9):
Chromosome 3 (position 16714800)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 3 | 16945019 |
| GRCz11 | 3 | 17094819 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTCAGTAACTCAACCCTACCTGAAGACCAAGTTCATCTGTGTCACCCC[G/A]TAAGTAGCACTTATTTCTTCCTCTCWGAGTGTGTGTGTGTRTRTGTGTGT
Long Flanking Sequence:
TTTGTAATCATCTCAAAAATCATATGGACCTGTGTTAATTTCATCAACAAAAATATTTGACGATGACCTTTTATTCCCCGACAAAGACAGGATGACTCAGATGTCATTAGATACTAAAAGTGACTACATCAATATGCAGTATTGTTGACGAGAAGACTAAAATGTAGTCAGAAGGCTAAGAACAGACCAAAAACCTCTGTTTTCATCAAGGTTAATTCTTTGAATATTTACTATATTATGCTGTTTATTCATTAGATGAGGTGATCAAAACGTGTGCATTTATAGTTTCTGTTTAGTTCAACTTAGACTGTTTCATGACTTTTTTATGATTTTTTTTAAGTTGTGTTTTTTTTGTGTGTAATTTTATTAATTTTTGTATATTTTCCTTTTTATGCCAGCAGCTCAATTTAAAGTCCGAAACTCATTTGACCACATCCATTTCTTGCTTTTTTTTCAGTAACTCAACCCTACCTGAAGACCAAGTTCATCTGTGTCACCCC[G/A]TAAGTAGCACTTATTTCTTCCTCTCTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTATGTGTGTGTTTGAGTTTGCTGGAGTCTCTCTGTCCTCTTGTAAACTCTGAAATCTCTGGTGACTCTTCAGGCAGGAGCATATGCCTCCACTCAGTTCACTTTACACCATGGATCAGGGATGTAGCCACTACTGACTCTCCTGCACGGACCCTTCACATCACATCATCCTAAAAAAAGCACAATCTTGCACAGGAAGAGAGAGAGAGATGCTTTAAAACATAACACACACACACACACACACACACACACACACACACACACACACACACAC
Associated Phenotype:
Not determined