ZMP
limk2
Ensembl ID:
ZFIN ID:
Description:
LIM domain kinase 2 [Source:RefSeq peptide;Acc:NP_001002651]
Human Orthologue:
LIMK2
Human Description:
LIM domain kinase 2 [Source:HGNC Symbol;Acc:6614]
Mouse Orthologue:
Limk2
Mouse Description:
LIM motif-containing protein kinase 2 Gene [Source:MGI Symbol;Acc:MGI:1197517]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa33573 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa45196 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa16581 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa33573
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000093185 | Nonsense | 203 | 651 | 6 | 16 |
| ENSDART00000142894 | Nonsense | 213 | 219 | 7 | 7 |
The following transcripts of ENSDARG00000005104 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 22629295)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 20342167 |
| GRCz11 | 5 | 20845967 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGGGATGCATATTAGTCCTGAGGTTCGGAATGCCATCCATGTTGGGGAC[C/T]GAATCCTGGAGATCAATGGACTCCCAGTGACATCCCTGATAGAGGAAGAG
Long Flanking Sequence:
ATGGCAAAAGAGGCTTCTCTGTCAGCGTGATTAGAGACTGCACCAGTGCCATTGCCAGCGTCCAGGTTAAAGAGTAAGTGAAGACATTAAGAATCAACATGAAAACACTTGATGCCTTGCTTAAGATCTTGATTTGAGTCCTGGTTTGGCTAGCAGTCATGTTACTGAAAAAACTCTTGGAATAAATTCTTGCTGAAGTTATTTATCACCTCAAAGATTCACTACAATGCCACCACACCCCATGCCAGAGACACTGTTAATGCCACATGGAATGTGTTGCATAACTGTGGTGATACGACTGCTCGTTTTAGATTGAGGGCCCTAACATGGCACTGTTTTTGTGTTTACTAAAACCGAAATCATAGTAAAAAAGCGATAACATTTATCTCTTCATTCTTGACCAGTCTTCTTACAATGCAAATCTCCCAAAATCTTATCCTTACAGGGTCAGAGGGATGCATATTAGTCCTGAGGTTCGGAATGCCATCCATGTTGGGGAC[C/T]GAATCCTGGAGATCAATGGACTCCCAGTGACATCCCTGATAGAGGAAGAGGTACTTTCCCTTTTAACCACAACTTTAGTTTCTTTTTATGTACGGTGAAATTGTGCTCGTGGGTACGTGTTGAAGCAGTATGATTATACTGAGGAACGGCATGGTAAACGTTTATAAACTATAAACTCATACCATTGCTTGTCCCAGCACATACAGTGACACTCCTTTCATACCGGGGTAATTGCGTTTGGGTCGTGCTCTGACTTTACAATACTCCCTAGAACAGGCTGTGTTTGTTAGATGACTTTGATGTGTTTTTTTTAGTATAAGCCATATGACACGTTGCTAACTTCGTTGACATGCTTCATGTTTTGTCAAATTGAAGTTAGGCGTGTTAAGGCTACGAAAGCAATACATATATAGTTTTAGTATGAATAATATTAAGTAGTCAAGTAGGGATGCTCCGAGCTGATACTTCGATCCGATTTCAGCTTTGATACCACATTTTCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa45196
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000093185 | Nonsense | 511 | 651 | 13 | 16 |
| ENSDART00000142894 | None | None | 219 | None | 7 |
The following transcripts of ENSDARG00000005104 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 22639443)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 20352315 |
| GRCz11 | 5 | 20856115 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAACTAATAAGAAAAGGCTGTTTAGACGCATTGATCGCAAGAAACGCTA[C/A]ACGGTGGTGGGGAACCCTTACTGGATGGCCCCAGAGATGCTCAATGGTGA
Long Flanking Sequence:
GTTACATTCACAGCACAAACAAATGAAGAGTTCAGATGCAAAAACCGTCTAAAATTCTTCTTACATTTGCATTTCTCAACATCTAGTGTTGATGTTCAGTTATTTCAAATTAAAGGTCATGAAAAGAACGTATTCTTTGCCATAAGTGTGAAAATACTGAAACTACACAGAAGCCTGAAACCCCCCCTCACAGATTTTAGATGAAAATTTTTGAAGGCGTTTAGAGGTGTTAGTATCTGAACTCTTCACATTTTCTTTCTATTATACATTGACAGCCAGTTTAAATGACCAATCTGCACTTATGTCATTGTTAAGCCCTGAATCTGTTCTGTCTGTTCATCTTTGCTCTACTTTTTCTTACCTCTGCAGGACAACACCGTCGTGGTGGCAGATTTTGGTTTATCTCGGTTAATCATGGAGGACAAAGTAAAGCAGCCTCCCCCGGACAAACCAACTAATAAGAAAAGGCTGTTTAGACGCATTGATCGCAAGAAACGCTA[C/A]ACGGTGGTGGGGAACCCTTACTGGATGGCCCCAGAGATGCTCAATGGTGAGAAGTTGGTTCCAAACCTTCTTCAGTTTCTTTATTCTCTTGAACACTAAAGATGTTTTTAAGAAAGCTGAAACCCGGTTACAACTGACATCCATAGTAGGACAAACAAATACTACAGGTCAATAGTTACAGGCTTCCAGCTCTCTTCCGAATATCTGTGTTTAACAGAAGAAAAACACAAACAAGTTAAGGGAAAGTTAAAGATAACAGAACATTTTTTTGGGTGAACTGCTGCTACTGACACATAATAAATGTGCAAATGCTTATGTTTGCAATAATTTATGAAAAAGATGTTTCAATTTCTTTCAACTTTTTATAAGTCTAGAAAAATACAATAATTGGATCCAAAGTCTAATTTTACACTTGTAAATGTATAATTGTCACCATTTTTAATACTGAATTGTTGAATTGTCGCACCAATATGTTTTTTTTTTTTTTTGGCCGATACTAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16581
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000093185 | Nonsense | 579 | 651 | 15 | 16 |
| ENSDART00000142894 | None | None | 219 | None | 7 |
The following transcripts of ENSDARG00000005104 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 22643005)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 20355877 |
| GRCz11 | 5 | 20859677 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTGGGCTGAATGTGCGAACSTTCATYGAGAAGTTTCTTCCTGAGCACTG[T/A]CCTCCTGCTTTCTTTGCATTGGCTGTGGCCTGTTGTGACCTCACTCCTGA
Long Flanking Sequence:
CCAAGTAACTGTCATTATCTGCAATGAAACAAAGGTGTTTTTGGGTTGTGTTCAATAGGCTTGTTTTTCTTGATTTCTTTCATCTCTGTGTAAACAGGTAAACGCTACGACGAGAAGGTGGATATTTTCTCCTTTGGCATTGTACTCTGTGAGGTAAGAGTCCTTTGTTGTTGTAAACATCTCCCTTTTTATAGTACGTCTTTATGAGGACAGCATGTTCTCTAAGAACTGTCATTTATGTAAGCGATTGCATACGAATGTGGGAATGCCAAAAGCAAGCGCTACGCTCAACTGGTTTTAGTCAAAACTGCTACATTTCATTCTTTGTTATATAAGAGGATGCTTGAAAGTTTCATCATCTTTATTTCTTCTTATTCATTCTTCTTCCCTTTGGAATAGATTATTGGTCAGGTTTATGCAGATCCCGAGTGTCTTCCAAGAACACTGGATTTTGGGCTGAATGTGCGAACGTTCATCGAGAAGTTTCTTCCTGAGCACTG[T/A]CCTCCTGCTTTCTTTGCATTGGCTGTGGCCTGTTGTGACCTCACTCCTGACAACCGGTAAGTCACAAATGTGTTTTTTTAACAATAATGTTGAAGGTAAAAATAAAATGCATACAAGATGTTTTAGCTCATCTTTCACTGGCTATAAGTCATAGGTCTCAAACTCAATTCCTGGAGGGCCACAGCTCTGCACAGTTTTGCTCTAACTGTAATGAAACACAACTAAACCAACTAGGCATGCAGTGATTAACTGATTTCACTATTAACCACGCTTTAATTCGTCATGGTTAATTATTTATAAAGGCTTCTCATCAGTGTTTCTGCCTGGAACAAAACTGCTGCAACTAAACAACGTTATGCTAACTGTGCGTTAGTTTAAATTTCTGTACTTGTACACTGAGGCTATTACACACACACACACACACACACACACACACACACTGAATTAACTATGGCTGACTGTGGCTATAAACTAGACCATTCACATATCACGTCTTTTGC
Associated Phenotype:
Not determined