Busch Lab

ZMP

smg5

Ensembl ID:
ENSDARG00000041481
ZFIN ID:
ZDB-GENE-050913-144
Description:
protein SMG5 [Source:RefSeq peptide;Acc:NP_001020094]
Human Orthologue:
SMG5
Human Description:
Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) [Source:HGNC Symbol;Acc:24644]
Mouse Orthologues:
AC101827.1, Smg5
Mouse Description:
Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) Gene [Source:MGI Symbol;Acc:MGI:2447

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa25030 Nonsense Mutation detected in F1 DNA Not yet available
sa42810 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa16480 Nonsense Available for shipment Available now
sa42811 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa25030
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060809 Nonsense 276 1099 8 22
Genomic Location (Zv9):
Chromosome 16 (position 48768760)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 45737981
GRCz11 16 45704697
KASP Assay ID:
554-7312.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTACCACCAGGTGAAGAAACAAGAAATGAAGAAGCTTTCACCATCTCGA[C/T]AGAGGTGTGTTTCCTCTCTTATATACTTATAAAAGACCGGATGAAGGAAT
Long Flanking Sequence:
CGGTACCGTACAAAGTGAGTTTGAACAAATCTTTTGAATGAATAAATCAGTGAATCACTCATTAAGACCTACTGGACATTTAGGGTTACTTTTGATTTTTCTATGACATTCCAAACTCACCCAAGGAGCCATCTTTTAGCATATTGAGAGGCCTTTTTATTAAATATTGCACACTCCTGCTAAGAACACAATCCTATTTATTCATATAAAGTTAAACTATAGACAAAAAATGCATACAAAAGCGTAATAGTAATAATGAATGAGCTACATGACTGATCTTTTCTTTTCCTCCTTATGAACTGTGGTTTTGAGTGATTAGCATTCCAAGAATCTGATAACGCTACATGAACATGAGCATCTGGTTTGTCTTGTTGAACAGTATTCAGTCAGAGACTCCCTTCGACGGTGCGTATGGGAATTTAAAGCGTCTGTTTGACAAGGCATCCAAGATGTACCACCAGGTGAAGAAACAAGAAATGAAGAAGCTTTCACCATCTCGA[C/T]AGAGGTGTGTTTCCTCTCTTATATACTTATAAAAGACCGGATGAAGGAATGTTTTGTTGGCCTGTCCTTTTGTGTTCCCGTGATCCAACCCTGTTTGACTCATTTGCCACCTCCCTTTGTTTAACAGCATATTCAATGGCCCCTCATAAAGGCTTTAATATTACTACCAGTATTTCGACTGTAATAATGACAAAGCCTATATTATATGCAGTGCTCCGCATATATAAGCACACCCCCACGAATTTCTCATTTAAATTAATATTTTCATAGAATGCTGTACAATATAATATTTGTGCATATACATGAGTTTAGTCAGAACTGAAGACAAATTTGGAGCTTATCTAACAAAATAACTTACAATAATGGTTCAAAAATGAGTAGCCTAAATCTATATGCTAGAAAAGTATATTAAATAAAATTTCATAAGTAGCAAAAATCAATATACAATTTTGTCTGTTATCTGTTTTAATTATCTGTTTAGCAAATCTGTTCAAATGCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42810
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060809 Essential Splice Site 371 1099 10 22
Genomic Location (Zv9):
Chromosome 16 (position 48772476)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 45741697
GRCz11 16 45708413
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGATGGTGGTGATTTGTCTGATGGTGGTGCACAGCCTGAAGCGAGGGGG[T/C]GAGCGTGCACTGAAAGAACTGATTATGTTATTCAGTATCTGATGCTTATT
Long Flanking Sequence:
TCAAATATAGAGTGGGCTGCTTTACATTTGATGCTTCTAACAGTACTCTACAGCGCCCTGGAGACAAGGTGGAGACTTGCATGGGCAAATCAGCTGTGATGTTAATCTGGTTGTTCTTGCTGCAGGTCAAAAGACATCAAAAGACTGCTGGTGAGCTTCATGTATTTGCAGAGCCTGTTACAGCCCAAGAACAGGTGAGAGTTTCAGCCTTAGTTCAAAACGTTAAATTATTTTCAAATCGTTAAATCAAATCAGCCTAATTGATTTCCTGTCACTCTTTTTTTCAGTCTGATGGAGACGGAGCTGACGTCGCTGTGCCAGTCTGTGCTGGAAGACTTTAACCTGGTGCTTTTCTACCTGCCTCTTCCTGCTCATGGCAGCCAGTCGGCCAGCGAGGAGGAGGAAGAGCACGACTCTGTTGGTTCTGTGCTTCCAGACAGCCTTATTTTCAAGATGGTGGTGATTTGTCTGATGGTGGTGCACAGCCTGAAGCGAGGGGG[T/C]GAGCGTGCACTGAAAGAACTGATTATGTTATTCAGTATCTGATGCTTATTTGTGCAGTGTTAAGCAAATAGATACTGCGTCAGCAACCTAAAAATAGTGTTGGAATTAATTCTTCAAGCATTTTAAGACATGCTTCATCATGCATAAGGCATATTCATGGTGAATGCTGCATTCTAAACAATTTAACATATTGTAACAGGATGAAAAATACATATTTGATTTATCTTTTTGGTTCAGACCAGCCAATATGTTCCTTTTTTTTCTCATTTCCTTACTTTTTTTAGCTATATAGTTTTATGTATGCTTTTTTAACATGCATATAGAGCCCTGTTATTTCATAATTGTAACCTAAACTGGTTTTCTCTAGTTAGTTTCTTCAATTAATCTAAAATACTTAATATATCCTTTTGTTTCAGCCTTAATTAAGTTAATGAAAAGCTTTTTTAATAGGTTTGATAATACAAATGCCTTCAAACAACAGTTCTAATCTTAATACCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16480
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060809 Nonsense 462 1099 12 22
Genomic Location (Zv9):
Chromosome 16 (position 48774506)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 45743727
GRCz11 16 45710443
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGAAGAGGAGGAGGAAAAGGAGAACGGGGAAGACGAGCCTAAAGGCAAC[G/T]GAAGAACTGTGGCGACAAAGAAAAACCAGGAGAAGAAGAGATCAGCCGAG
Long Flanking Sequence:
ACAATTCTTAAATTAAGAGGAAATTTCTAGACATTTCTAGCCAAATATGTTAAAATAAAGTCAGTTTTTCTTTTTTTAAAACGACAATATTTTTTGCTTGTCTAGAAAATGCTTCTTGATATTTGGATTAGAAACTAGAATATATAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAATTATTATTATTATTATTATTTTATTTTTTTCTCCAGTTAAGCCTGTCGCAGTACTGCATTGTGTGTACTTGGGACATGGTGTAATAAGAATTTTGTAAAGCCTTTGTCTATTTTATTTCTCTTGTAACTCCTCTCTAACCGATGCATTTGTTGGCAGATGACGCTGATGCCAGAGATCACAGTAGTGCTGCTCTCTCAGAGGAGCGAACCCTGCAGAACGGCTCTCTGGAGGAGGATGACGATGAAGAGGAGGAGGAAAAGGAGAACGGGGAAGACGAGCCTAAAGGCAAC[G/T]GAAGAACTGTGGCGACAAAGAAAAACCAGGAGAAGAAGAGATCAGCCGAGGAGAAGCAAAAACAGAAGCGGAAGTTCTCAAGGCTCTCCATGCTTCGCCGAAGACGCTGTGCTCACAAGGAGGATGAGAGCGACCTGAGTGAGGGCTTTGAGAGCGATGAAGAGGAGGAGGAGGAGGAGGAAGGTGGTGGCGGTGGTCTGGTTGATGGTCTGGGAGCCCCCAGGGTCCAGATGAACTCTTTAGGAAGAGACACACGGAAGGGGCCACTGCCGGAGGACGGCGGCTGGGAAAGCGGTTCAGAGGAGGATGAGGGTGGCACGGCTTTTGACGTGGAGACAGACTCTGACATGAACAGTCAGGAATCGCGATCGGATCTGGAAGACATGGAGGATGCTGAAAATGCACCACAACAGCCACAACAAGAGGAAAATGAGCAGCCGCAAACGTCTAGAGAGGAAAACGCCACCCCTCCAGTAACCAATGGGCCGTCTGTGTCTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42811
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060809 Essential Splice Site 1072 1099 21 22
Genomic Location (Zv9):
Chromosome 16 (position 48790775)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 45759996
GRCz11 16 45726712
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACTGGACACTCATTAGAGGAGCTGAGTGAAAGATCGGCTTCCATGAAGG[T/A]CAGTCATGCACAAGACTCCAAGTGAGCTATTATGTAAAACGAGTTTGGTA
Long Flanking Sequence:
TGAAAACCCTTCCTTCAACACTATACCGCTGAAAACACACATCACATGACCACATACACACACTCTGGCATGCGCTTCAGCAGTATATGCGCACGTCTGAGCTCCAGGCAGTCAATATGGGCCGCTTTGAGCACAAAATCCCAGTGAGCAGTGCAGTGTGATAAATGCACAAATGGTCATTTATTCTTACTTTATTGTGCAACAGGTACATCCGCTGTCAGAAAGAGTCAGGAAGAAGCTTTGAGAGGGACAAACTAAAACGTCAGGACACAGAAGCCTGGTAAGTCACCTGATGTTTTAGAGCGTGAAGCTCTGTATAGTTTTCTGCATGCCCTGTATTGACGGTTGACTGTTATACAGGCACCTATATAAGATGGTGGACAGCTGTCGTCAGCTGACGGGATCTCAGAGCAGTGGAGATGAAGACACCGCCGGCATGGTCACCATTCTCACTGGACACTCATTAGAGGAGCTGAGTGAAAGATCGGCTTCCATGAAGG[T/A]CAGTCATGCACAAGACTCCAAGTGAGCTATTATGTAAAACGAGTTTGGTAGGTGCCAGACCATGTGGTTGTTTTTATTGCTTTGGTGGAGTTTCACTTCACTGGATCACCCTTTAGCAGTGACATTCATACTAAACTGATCTGAAGCGGTTTCAATTGATAGAGAACGACACCAGCATTCTACATTACATGTTGTCTCTTTATTTTTCAGTTAGGTTAGGCTGATTTGACACACTCTACATTGTGATAAATGCTATAGAAATAAAGATGATCTGAATTGAAATATTGGAAATGTCATATATTCACTCACTGGTCACTTTTTTAGCTACCTTGCTAGGACAAAGTTGTACTGCATTGTCTTTTCAGAACTGCTTTAATTGTTGATGGCATCGATTTAAATATAGACAGAAAACATTCCTCAGAGTTTTTGGTTGTTGACATGATTGCAACAAACAGTTACTCCAGGTTTTGTCAGATTTCTACAATTGCAGCACATTTCAA
Associated Phenotype:
Not determined