ZMP
th
Ensembl ID:
ZFIN ID:
Description:
tyrosine 3-monooxygenase [Source:RefSeq peptide;Acc:NP_571224]
Human Orthologue:
TH
Human Description:
tyrosine hydroxylase [Source:HGNC Symbol;Acc:11782]
Mouse Orthologue:
Th
Mouse Description:
tyrosine hydroxylase Gene [Source:MGI Symbol;Acc:MGI:98735]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa38085 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa1635 | Essential Splice Site | F2 line generated | Not yet available |
Mutation Details
Allele Name:
sa38085
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040410 | Essential Splice Site | 97 | 489 | 3 | 13 |
| ENSDART00000044624 | Essential Splice Site | 4 | 110 | 2 | 12 |
Genomic Location (Zv9):
Chromosome 25 (position 24793346)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 25 | 23972459 |
| GRCz11 | 25 | 24070007 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGAGCACTATTTTCATAATATTTATTTTATTATATCAATTGAACACCAC[A/T]GACATTTGAGGCCAAAATCCACCATCTTGAAACCAGACCCAGCCGAAAAC
Long Flanking Sequence:
ATTTTAAAGGAAATTTTTAGATGGCACTTCTTCACTTTGGGACAATGCTTTGAGTTTTTTTACACTCTGTAAGAATTTACTACCTATTTGTTATGTTAGGGATGAAAACATCCACTGAATTAAACTGCTGTAAAAATGCATAAGATATTTTTATCTTAATTTATTTGGCATAAATCTGTTAATCAACCTCAGTACTGATCAAAACTACTTAATTGTTTAAAAAAGTACATGATTTTAACTCTTTAATTGCCAAATTCATAAATTATGTCACTGATTTGATGAAAAAAATGCACAAAATGTTGTATTTTCAATGTAAAATGTGATTGTGGAGTGGATTTTTTTAAACCTTTAACAGTGCACAAGGGTTAAATATATTTTGATTGTGTTTGATGTTAAATCTTGTTATGTATTAATAAGCATTAAATTATATTTTAAGATATTACATTAATTTTGAGCACTATTTTCATAATATTTATTTTATTATATCAATTGAACACCAC[A/T]GACATTTGAGGCCAAAATCCACCATCTTGAAACCAGACCCAGCCGAAAACCAAAGGATGGCTTGGAGGACCTAGAATATTATGTTCAGTGTGAAGTGCACCTGTCGGATGTTAGCACGCTGGTCAGCTCTTTGAAGAGAAGTGCAGAGGATGTCAAAACCACAAAGGAGGTCAAATGTAAGTCTGTTAACCTGTGACCTTGCTTTGTTTTTGATTTTCTGTTGTGCTTGGTTGTTGGACACTGCATTTTATGACTGCAGGTTAACTATGCACAGGTATTTGAAATGTCATTTCAAATTTGTTAGGAAAAACTTCCATATATACATTACATTCATTCATTTTCTTTTCAGCTTAGTCCCTTTATTAATCAGGGAGTACCACAGCGGAATGAATCGCCACATACGCAACAGTTAAATTCAAATGAACAGTCAACATGTGATAAGCATTTCTTTTTGTAGAATAAACTAGGTAAATATGATATATTGCAAATGAATAATAATT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa1635
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040410 | Essential Splice Site | 360 | 489 | 10 | 13 |
| ENSDART00000044624 | Essential Splice Site | None | 110 | 9 | 12 |
Genomic Location (Zv9):
Chromosome 25 (position 24783281)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 25 | 23962394 |
| GRCz11 | 25 | 24059942 |
KASP Assay ID:
554-1575.1 (used for ordering genotyping assays)
KASP Sequence:
TTTGGCATCTCTTGGAGCTTCTGATGAAGATATTGAGAAGCTATCGACAG[T/A]AAGTATAAATCATCTCAAAGCTTATGAAACTCAGTATTTTAYATGTAAAC
Long Flanking Sequence:
TGATCGAACATTTGCACAGTTTTCTCAGGTAAAGGCATCAGCATTAAATGCATATTTTCATTCGGTCACACTTTACAATAAGGTTCATTAGTTAATGTTAATTAATGCATTTACTAACATAAACAAACAATGAACAATACATTTACTACTGTATTTGTTCATGTTATTTAATGTTAGTAAATGAAAATAAAGTTGTTCATTGTTAGTTCATGTTAACTCATGGTGCATTAACTAATGTTAACAAGCATTGACTTGGATGGTAATAAAACATTAGTAAATGTTCAATTACGATTAATAAATGCTGTACATGTGTTGTTCATGATTAGTTCAGGTTAGTAAATGCATAAACTAATGAACCTAATTGTAAAGTGTTACCTTCATTTCTTTTTATTAAGTGCATATTCAATCTTTAATTTATGTCCTTCAATCTCTGTTCTTTCAGAGTATTGGTTTGGCATCTCTTGGAGCTTCTGATGAAGATATTGAGAAGCTATCGACAG[T/A]AAGTATAAATCATCTCAAAGCTTATGAAACTCAGTATTTTACATGTAAACTAACTACTGTATGTGTTGCAGATGTACTGGTTCACTGTGGAGTTTGGACTGTGTAAACAGGGAGGGGTGATTAAAGCGTATGGAGCAGGACTGCTGTCATCCTATGGAGAGCTGGTGGTAGGTGGCCTTAAGTCATTTGTTTACCCTTGTATAAATGACTGAATCTCAAAATGATCTTTTTTTTTAAATACTGCATGTCTTCATAATTTTTTTAGGAACTTTAACATGTACAAAAGAAAACGAAACATACAACATTATTAAAATAAATAATAATAAAAGTATGTAAGAAATAAATCCATGTACATACACATACAATATAAATATGCATTAAAACAATGGCATATTAATAGAAGGTGACGCAAGATAGAAGTTATATAGACAAAAGATTTTTATCACTTTTTTTTAGAAATCCTACAAAGGGTTTTTATATTTTGAAAAACTTTTCAGTTT
Associated Phenotype:
Not determined