ZMP
tgfb1a
Ensembl ID:
ZFIN ID:
Description:
transforming growth factor, beta 1a [Source:RefSeq peptide;Acc:NP_878293]
Human Orthologue:
TGFB1
Human Description:
transforming growth factor, beta 1 [Source:HGNC Symbol;Acc:11766]
Mouse Orthologue:
Tgfb1
Mouse Description:
transforming growth factor, beta 1 Gene [Source:MGI Symbol;Acc:MGI:98725]
Alleles
There are 4 alleles of this gene:
Allele Name | Consequence | Status | Availability |
---|---|---|---|
sa16296 | Essential Splice Site | Available for shipment | Available now |
sa39024 | Nonsense | Mutation detected in F1 DNA | Not yet available |
sa42471 | Nonsense | Mutation detected in F1 DNA | Not yet available |
sa39023 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa16296
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000060839 | Essential Splice Site | 108 | 377 | 1 | 7 |
Genomic Location (Zv9):
Chromosome 15 (position 2794641)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 15 | 2839705 |
GRCz11 | 15 | 2802988 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGATGAGGACTAYTTTGGCAAGGAGGTGCATAAGTTCGTYTTCCAGCAAG[G/T]TTAGACATTTAAAGTACTTTTTTTTNNACTTCTTATTGTAGTATTCGATR
Long Flanking Sequence:
GGTCTTAGGAAATTCCCATATTGACGGACATCATCTGTTCTGCTGAGTCCATTATTCAAGGTGTTTTCCAGACTCCTCAACAGGTAGCATCACCTCTATAATCAGACGCTTTTCGATCCTTTCCATTTCATTTTTTCCTTGCTCGCTGGACAGTTTGGTCGTACATTTCAGCATTATGAGGTTGGTTTGCTTGGTGCTGACCGCCCTGTGTTTGGTCACGGGAACGGGCAGCATGTCCACCTGTAAGACTCTGGATTTGGAGGTGGTGAGGAAGAAGCGGATTGAGGCTATTCGGGGTCAGATCCTCAGTAAACTGCGCATGGCTAAAGAGCCTGAATCCGGAGCGGACGACGACGGACAGAAGATCCCGGATTCCTTGCTTTCGTTATATAATAGCACTGTTGAACTGAGCGAAGAAATGAAGACGAAGATCGTCCCTGTGCAGGATGAGGATGAGGACTATTTTGGCAAGGAGGTGCATAAGTTCGTCTTCCAGCAAG[G/T]TTAGACATTTAAAGTACTTTTTTTTTTACTTCTTATTGTAGTATTCGATGTTTATGTTTATGTCAGCATTCTGTCATCAGATATTATGAACAATAATCATTGTGTAACTGTGTTTGAGTTGCTTTATGATGATAGGAATGTAAAATGGTTGCACAATTCATTTAAAGTCTATCCTAGACAATCAATTCACTACTTGTGTAATTTATTCGAATCTTATTGTACTCGTGTTGATATACCCCACGATGTGATGTTGATGATCACTAGATATTTTTCAACATACTAATATTCAGCTTAAAGTAAGTAGGTAACTACTTAACTAGGTTAACTAGGCAGGTTAGGGTAATTAGGCAAGTGTTTGTATAACGATGGTTTGTTCTGTAGATTATCGAAAAAAAAAGAGGCTAATAATTTTGTCCCTAAAATGGGTTTTTAAAAATGTAAAACTGCTTTTATTCTAGCCGAAATAAAACAAATAAGACTTTCTCCAGAAGAAAAAATAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa39024
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000060839 | Nonsense | 275 | 377 | 4 | 7 |
Genomic Location (Zv9):
Chromosome 15 (position 2778752)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 15 | 2823816 |
GRCz11 | 15 | 2787099 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGCATCCGTTCGCAAGAAACGAGCTGTTGGCACCGATGAAACATGTGAT[G/T]AGTAAGTCTTTTTGCTGTCCTATGCTTTATATACAGCTGAAGTCACAAAT
Long Flanking Sequence:
TATTTACACAATAAGTACATTGTAACGAATTGTTAATTTCAAGTACATATTAGTTAAGGACCCTTATTATAAAGTGGGACCTAGTATTTTAAAGTGCAAAACAAGGTTTATTAAATGCTGTATGTATATTGTGTTTGTGTTTAACAGAAGATGAAGAAACCTTGGAGCTGAGGTTATACTGCGACTGTAAAGCAAACCAGCAGAGCACGGATAAGTTCCTCTTCACTATATCAGGTATGATAATCTCAGTAATCTGAAACAGTGCTGGATGTTTATGATGAAATAAGCTGATATGCTTATTTTTTTATCTTGTTTGTTTTCTTTGTGTGTGTGTGTGTGTGTGTGTGTGTTCAGGGCTAGACAAGCAGAGAGGTGACACCGCTGGTCTGGCAGATATGATGGTGAAGCCGTACATTTTGGCTTTATCTTTGCCTTCAAATGGCAACTCTCTTGCATCCGTTCGCAAGAAACGAGCTGTTGGCACCGATGAAACATGTGAT[G/T]AGTAAGTCTTTTTGCTGTCCTATGCTTTATATACAGCTGAAGTCACAAATGTGGCACAGTGGGTAGCACAATCACCGTACAGCAAGAAGGTCGCTGGTTTGAGCCCCGGCCGGGTCAGTTTCTATGTGGAGTTTGCATGTTCTTGTGGCTGGAAGGGCATCCTCTGCGTAAAAAACTTGCTGGAAAAGTTGTCGGTTCATTGCGCTGTGGTGACCCCGGATTAATAAAGAGACTAAGCTGACAAGAAAATCAATGAATGAATGAATGAATGTTGTTTTGTCATGTTCACCTTTTTGCTGGATTTTTGTCTTCACTTTGTGTAAAATAAATCACGCTTCACCTTCAACAGCGGCTTCTGTGACACTTTTTGCCTCCATCCGCCCGGTCAATCGTAACACTACCTTTCAGAATGGCTTAACACTAGTGCACTAGACTATGTGTGCCTTGGCTACTTTGCCGACCAGTTCAGCTAGATTATGTGTGCCTGGGCTACCTTGCTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42471
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000060839 | Nonsense | 300 | 377 | 5 | 7 |
Genomic Location (Zv9):
Chromosome 15 (position 2776073)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 15 | 2821137 |
GRCz11 | 15 | 2784420 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAAGCTTTACATTGACTTTCGGAAAGATCTGGGTTGGAAGTGGATCCAC[A/T]AGCCCAAGGGGTACTTTGCCAACTACTGCATGGGGTCCTGCACCTACATC
Long Flanking Sequence:
CGTGTCTCCCTCCCGGTCCTCAAATAGGCTACATCACGCACCCTTTTCACCCCTCCCCACCGCATCTCTCCTCACTCTTCAGACACATCGCGCCTCCACCAAACCACCACCTCTCCTGACAGCTGAGCGGGACTCAATAAACCCTGACACTCTGACCAATGTGAGGAGAGTTTACTCGCACGTGACTTGTTTTAGCTCTTTTGGTCCGATTAGAAACTTTGCAGTGTGAAAGCGAACCGCTCCAAGAGCAAAGAGCAACAATGTAACAATTGTAATCTCTGTTTCGGAACAACTGAATCGATTCACAGGTGTGAAAGCAGCCTTATTCATTAACTGCTATAGTTACAAAAGTTGAATACTGCAGCTTTAAGCAAGAACCACTGAATACAGATAATCAAAATCTCTCCTTCCCAATATTCTCTGGCAGAAAAACGGAGACCTGCTGTATGCGCAAGCTTTACATTGACTTTCGGAAAGATCTGGGTTGGAAGTGGATCCAC[A/T]AGCCCAAGGGGTACTTTGCCAACTACTGCATGGGGTCCTGCACCTACATCTGGAATGCTGAGAACAAATACTCACAGGTAGCCTGTTTTGTTTTGTTATTACTGTCCCATTTAACTAACGTGACAAATTATTAAAGATATAAACAAACTAGTCATTAAATCTATTCAATAGTTATTTTATTAGTTCCTAAACTCAAGGTTGCTGTACAAATATAATGTTATAAAAATGTGACAAATTACAGTCATGCACTTTGGATTTTGTTGCCATGTTTTTTTTTTTTGGGGGGGGGTGGGGGGGATTTTGTTGCCTCTAGGGATGGTGCACAACATCCCTGCTGAAAAATCCAGCTTATTCTTAAACCAGCTGGTTTAAGCTGGTTGACCAGGCTGGTTTTAGAGGGGTTTTGGGCATTTCCAGGCTCAATTCCAGCCTGGTTTTAGCTGGTCTGGCTGGAAAATTACCAGCTAAATCCAGCTAAATCCAGCAACCAGCTTGACCAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa39023
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
---|---|---|---|---|---|
ENSDART00000060839 | Nonsense | 320 | 377 | 5 | 7 |
Genomic Location (Zv9):
Chromosome 15 (position 2776013)
Other Location(s):
Assembly | Chromosome | Position |
---|---|---|
GRCz10 | 15 | 2821077 |
GRCz11 | 15 | 2784360 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTACTTTGCCAACTACTGCATGGGGTCCTGCACCTACATCTGGAATGCT[G/T]AGAACAAATACTCACAGGTAGCCTGTTTTGTTTTGTTATTACTGTCCCAT
Long Flanking Sequence:
CGCATCTCTCCTCACTCTTCAGACACATCGCGCCTCCACCAAACCACCACCTCTCCTGACAGCTGAGCGGGACTCAATAAACCCTGACACTCTGACCAATGTGAGGAGAGTTTACTCGCACGTGACTTGTTTTAGCTCTTTTGGTCCGATTAGAAACTTTGCAGTGTGAAAGCGAACCGCTCCAAGAGCAAAGAGCAACAATGTAACAATTGTAATCTCTGTTTCGGAACAACTGAATCGATTCACAGGTGTGAAAGCAGCCTTATTCATTAACTGCTATAGTTACAAAAGTTGAATACTGCAGCTTTAAGCAAGAACCACTGAATACAGATAATCAAAATCTCTCCTTCCCAATATTCTCTGGCAGAAAAACGGAGACCTGCTGTATGCGCAAGCTTTACATTGACTTTCGGAAAGATCTGGGTTGGAAGTGGATCCACAAGCCCAAGGGGTACTTTGCCAACTACTGCATGGGGTCCTGCACCTACATCTGGAATGCT[G/T]AGAACAAATACTCACAGGTAGCCTGTTTTGTTTTGTTATTACTGTCCCATTTAACTAACGTGACAAATTATTAAAGATATAAACAAACTAGTCATTAAATCTATTCAATAGTTATTTTATTAGTTCCTAAACTCAAGGTTGCTGTACAAATATAATGTTATAAAAATGTGACAAATTACAGTCATGCACTTTGGATTTTGTTGCCATGTTTTTTTTTTTTGGGGGGGGGTGGGGGGGATTTTGTTGCCTCTAGGGATGGTGCACAACATCCCTGCTGAAAAATCCAGCTTATTCTTAAACCAGCTGGTTTAAGCTGGTTGACCAGGCTGGTTTTAGAGGGGTTTTGGGCATTTCCAGGCTCAATTCCAGCCTGGTTTTAGCTGGTCTGGCTGGAAAATTACCAGCTAAATCCAGCTAAATCCAGCAACCAGCTTGACCAAAGCTGGACATACAGTAGCTGGTTTTGGCTGGGCTCCCATCCTGGCTAAGCTGGTCAAGCT
Associated Phenotype:
Not determined