Busch Lab

ZMP

hif1ab

Ensembl ID:
ENSDARG00000034293
ZFIN ID:
ZDB-GENE-040426-706
Description:
hypoxia-inducible factor 1-alpha [Source:RefSeq peptide;Acc:NP_956527]
Human Orthologue:
HIF1A
Human Description:
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Source:HGNC
Mouse Orthologue:
Hif1a
Mouse Description:
hypoxia inducible factor 1, alpha subunit Gene [Source:MGI Symbol;Acc:MGI:106918]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa16125 Nonsense Available for shipment Available now
sa23673 Essential Splice Site Available for shipment Available now
sa29335 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa16125
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018500 Nonsense 137 777 4 15
ENSDART00000047580 Nonsense 137 532 4 15
Genomic Location (Zv9):
Chromosome 20 (position 20410476)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 20438643
GRCz11 20 20338316
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTTTCTCTCTCTTAGTTTGATCTGACCGGKCACAGCATCTTTGAATTTT[C/A]ACACCCATGTGACCATGAAGAGTTGAGAGAGATGCTCGTCCACAGAACAG
Long Flanking Sequence:
GGCCACCAATATTACATGCATTTCTAATATAAGTATTAAAATACACTAAATTGTTTAATAAAATATGTTCTTGCAATATTTTATTTATAGTAATACAAAACAATTAATAGGAATGTACCAAGTTAGCAACATGTGATTGTATTTTTTCTTATACAAACCACTTAGTATCAGGTGTAAACATGACCTTACATTTATTATATTGCTCAGGGATGTTATTCGATTTTGCAGATGAAAAAGAGGAGAAGGAGGAGAATGAGCTGGAAAGTCAGCTGAATGGCTTTTATCTGAAGGCCCTTGAGGGTTTCCTTATGGTCCTGTCTGAGGATGGAGACATGGTTTATCTCTCTGAGAATGTCAGCAAGAGCATGGGCCTCACACAGGTACCTCGACGTCTGCATTTTCTTCTAAGCATTTCGATTAAAAGCTTATGGTGTAGCTAAATATCCTTTCCTTTTCTCTCTCTTAGTTTGATCTGACCGGTCACAGCATCTTTGAATTTT[C/A]ACACCCATGTGACCATGAAGAGTTGAGAGAGATGCTCGTCCACAGAACAGGTGAGCCACACACGACACATTCATACCACTGATAAATCAGTCATTAATAACAAATGCATTAACGTTTGTCTTCATCCTTATCATCCATGTTTAGGATCCAAAAAGACCAAGGAACAAAACACAGAGCGTAGCTTCTTCCTGCGGATGAAGTGCACACTCACTAGCAGAGGACGCACCGTCAATATCAAGTCTGCGACGTGGAAGGTGACATTGTCTTTTCAAACTGTTGCTAATTGTAGTCATAGCTTATATATAGCCTTCCACATATCTATACCTTTTCCTGGTGTATTGTTCAAGAAGAATACAATTCGTAAAGCAGATTTTAGTTAAGGAAGTAGGAAAGAAAATAAGCTTGAGTCATTTTTTGTGAAGGATATTTATTTTGTAGTTTTTATTATGTACAGGGTTCATAAGGGTGCTGGAAATTCTTGAAAATGCGTGAAGTTTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23673
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018500 Essential Splice Site 504 777 10 15
ENSDART00000047580 None None 532 None 15
Genomic Location (Zv9):
Chromosome 20 (position 20404069)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 20432236
GRCz11 20 20331909
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCAGACCCCACAAACACACCCTCCACATCTGGACTCGGCTCTTCGGGGG[T/C]AAACACTTATTAAACGCTTGCTATTCTTGGTCATTTAACAACAATTGCTC
Long Flanking Sequence:
TATAATGGGTGTGACAGACAATGTAGATAACCAAAACATGCAGTGTTGGTGGTCCTCCAGGCACATAGTTGAGAAACACTGCTTTAGAGGATTAAATGCAATCCCCTGGCAGCTTTTTATCTTATGAAGACTAACAACTCTTGTCATTCACTAATCATCTGAGATTACAGGAAATGTGCTTTCATAATTTTACTGAAGTAAATCTAATATTAAATACACACAGTTCCTTGGTGGTCTACCAATAATAATTACCGGTATCCATTTCCCTCCAGATTCTGACATACAGCTGCTGAAGGAGGTGCCCCTCTACAATGATGTCATGCTGCCTTCCAGCAGTGAGAAGCTGCCACTCAGCCTATCTCCTCTCACACCCAGCGACTCCATCCCAGCTCTGACCAAACTAGAGACTGGAGGAGAGGACTTCCCTTTCAGCTCTGCCTCTGATCGTGTGCCAGACCCCACAAACACACCCTCCACATCTGGACTCGGCTCTTCGGGGG[T/C]AAACACTTATTAAACGCTTGCTATTCTTGGTCATTTAACAACAATTGCTCCCTTGTAATGGTTAATGAGATACTGTCACTGACTTTAGGTTGTTTTTTTTTGTCAATCTTAGCCCAACAGCCCCATGGATTACGGTTTCCCAGTGGAACCAGACATCAGTTCTGAATTTAAACTCGACCTGGTTGAGAAACTGTTTGCTATTGATACCGAAGCAAAGACACCTTTTTCCACCCAGGTAACTTTTTATTTAAGATTTTAACTACATATTGTTTGTCTCACTCTCTCCCAAAATCAAATTCTAATTCAAATGAGCTTTATTGGCATGACTTGTCAAGTATTGCTTATATATTGCAAATATGAATATATATACACATGTACATAAAACACAATTACAGATTTGATAAGTACATATGCAAATAAAAAAGACTAAGTTTTTTATTTTATATTATTACAAAGAAAACGAAAGAAAAATAAATTATAAAAAAAACAATATTATAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29335
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000018500 Nonsense 775 777 15 15
ENSDART00000047580 None None 532 15 15
Genomic Location (Zv9):
Chromosome 20 (position 20400266)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 20428433
GRCz11 20 20328106
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGACCGCCACCATCTGCTCCAGGGAGAGGAGCTGCTGCGTGCTCTGGAC[C/T]AAGTCAACTGAGCTCTGCTGCTTTTAGCAACTGCGGACACTCTTCCCCCC
Long Flanking Sequence:
TCTTAATCAAATTATGTGCCAGAACATTTAAAACAGGATCATGAAGGGAACATTAAAAAAGCAACTCATGTAAACACCTTAATCATATTATTTTCTTATTCAGATTAAGGCAAATAATTCAATTACTGATGTCCATATAAAAGCTATTATAAAAACCCAACAAGAAATCCAATGAAAAATGTATTCATTTTTTAAAAAACAACTTTATTCAAGATGTACTTAAATAAAACTGTAAAAAAAATAATAATAATAATTATTTACAGCAGTTTTATTTATAGCTTCAGAGTCATTTTTGTAGCTCTAACTAAATCTGCATGTTTCCAGTTGTGAGTAAATGAGTTTTTTCTCTCTCTGCAGATGTGGCCAGTCGTCTGTTGAGCAGTTCTCTAGAGGGCAGCGGCGGCCTCCCTCAGCTCACACGCTACGACTGCGAAGTCAACGCTCCCGTGCAGGACCGCCACCATCTGCTCCAGGGAGAGGAGCTGCTGCGTGCTCTGGAC[C/T]AAGTCAACTGAGCTCTGCTGCTTTTAGCAACTGCGGACACTCTTCCCCCCTTCTCCCGAACCCCTGAAATCTGCCTCCACTTGTCTCCTTTTATCCCAAGCCCTAATATTCTCTAAAAACCCCAGTGTTTTAAAACGAAATGTACTAGACCTGCACCTTCCATTGATGTGAACAGGAGCCCAGAGGGAGTCAGTCCATCCCATCCCCAGTGTGTGCAGGGCCTGCAGACACAGGAACGTACCGATACTCAACAGTGGCATCAAGAGTTAAGAGCCTTAATGTGAAATGCACAACTCGCCCTGACACACAGATGCAGATGCGTACAATCCACCCCCACCACCCAAAAACTCCCTCTGGATCTCCGACTTTGACCTAAAAAGCCTCCCGCTGTGTTTTATCGCCCCCACTCCCAAAGCGTGTGTATTGTAGCTACAGTCGCACAATAATCTATTTTCTTAAGACAGAATACCAGCAGTCCATGCAATATATACGAAACCATT
Associated Phenotype:
Not determined