ZMP

ppme1

Ensembl ID:

ENSDARG00000009771

ZFIN ID:

ZDB-GENE-030131-7064

Description:

protein phosphatase methylesterase 1 [Source:RefSeq peptide;Acc:NP_956231]

Human Orthologue:

PPME1

Human Description:

protein phosphatase methylesterase 1 [Source:HGNC Symbol;Acc:30178]

Mouse Orthologue:

Ppme1

Mouse Description:

protein phosphatase methylesterase 1 Gene [Source:MGI Symbol;Acc:MGI:1919840]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa15990	Essential Splice Site	Available for shipment	Available now
sa43649	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa37316	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa15990

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000016219	Essential Splice Site	92	377	3	14

Genomic Location (Zv9):

Chromosome 21 (position 24668991)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	25354665
GRCz11	21	25391270

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GCTTCTGCATGGAGGAGGTCACTCTGCTCTKTCCTGGGCCGTCTTTACTG[T/G]GAGTTTAATATMTCTCTCAAAGYCACACATGAATACAAGCATAATATACA

Long Flanking Sequence:

TTGTATCAAACTCCTGAAAACAACTTGTCATCTTCATGTAGGCTATATTTTGTTTGAAATTGCTTCTCCAATTTGTTCTTCGATTTTGTTGTGCTTTATATCCAGTTGGTCAGACATTTAAACTGCAACGATATAAGGATATACAGTACATATAATATCCACAAGAACACTCAGATGTTAATGACATGATTTTTTTATGCAGACCAGGAAGAAAGCGAGATTTCTCTCCCCTTCCATGGAGTCATTACTTTGAAACTATTGAGGACGTGGAGGTGGAGGTGGAAAATGACAACAGCAAAGACATATCCTTTGTTTTACTGTGGAGCAGACTGTTGGCCAATTATGCTATTTTTTTATTCAGAGGTTTCCATCTTGTTTTGTGAAGCATCCTTTAACTCCTGTGTACACATTCAGAATTTACAGCAGTGGCTCTCATGGTCCCGTCCTGCTGCTTCTGCATGGAGGAGGTCACTCTGCTCTGTCCTGGGCCGTCTTTACTG[T/G]GAGTTTAATATATCTCTCAAAGCCACACATGAATACAAGCATAATATACAGTTGAAGTAAGAAATATTAGCCCTTCTGAATTATTAGCCTACCTGCATATATTTTTCCAAAATTTCTGTTTAATAGTAAGAATTTTTTCAACACTTTTCTAAACATAATAGTTGTAATAGATCATGTCTTATAACTGATTTATTTTATCTTTGTCATGTTGACAGAAAATAATATTTTACTTGATATTTTCCAAAACACTAGTTTTCAGCTTAAAGTGACATTTAAAGGCTTAACTAGGTTAATTAAGTTAACTAGGCAGGTCAGGGTAATTAGACAAATCATTGTATAATTATGTTGACAATCAAAAAATATATATTGCTTAAGGGGCTAATAATAATGACCTTAAAAGGTTTTTAAAAACTAAAAACTGCTTTTACTCTAGCCAAAATATAACAAATTAGACTTTCTCCAGAAGAAAAAATATTATCAGACAAACTATAAATTATATG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa43649

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000016219	Essential Splice Site	355	377	12	14
ENSDART00000016219	Essential Splice Site	355	377	12	14

Genomic Location (Zv9):

Chromosome 21 (position 24661113)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	25346787
GRCz11	21	25383392

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GGTTCTGCCACAATGTGGCCATGCCGTTCATGAAGATGCCCCAGAAAAAG[T/A]GTGTTTATTATCTATGACACTTTCAATAAAGCTTGTACATTATCCAGTAT

Long Flanking Sequence:

TTTTAATACAAAATTCCTTACATTTTCACACACATTTTAAGGAGAACAACTTTTTTATGTACAGATGTTTGTTGATTTTGTTTCATGTGGCAGATAAAGAAGGAATCTCTGTACACCTGGCGTATTGAACTCTCAAAGACAGAGAAATACTGGGAGGGCTGGTTTAAAGGACTGTCTTCCCTCTTTCTCAGCTGTTCTGTGCCAAAACTTCTTCTGCTGGCTGGTATGAATGTTTAGACATTTTGTTTAAAGTCTTATTGTGAAAAACAGCTACTTATATTTAATATATCACCCCATAGGTATTGACAGGCTTGACAAAGATCTTACCATTGGGCAAATGCAAGGTTAGGTGTTGATATTCCTGCTATTCAACGCAGACTTTATAGAGGGTACATCATACATTTATTCATTTATCTCCTTTTATTTCTGTACAGGGAAGTTCCAGATGCAGGTTCTGCCACAATGTGGCCATGCCGTTCATGAAGATGCCCCAGAAAAAG[T/A]GTGTTTATTATCTATGACACTTTCAATAAAGCTTGTACATTATCCAGTATGATGTATTTGTTTCTGATCACCTATATTTACATTTTTTTTCAGGTAGCTGATGCTTTAGCCACTTTCATGGTTCGTCACAGGTTCACTGAATTAAAGGAAGGGTTCCCCTGGTGAGAAATGGACATTTTGGCACATTCAAATAACTTTTAATATTTGGAAACTATTATAACTGATATAGAGGCTGATAAATGCACATTTTGATATGAAATTATCTGAGCCTGATTACAAAAAAAGACAAAAAATATTCCAGTGGAGATCAATTTAATTTAAAAACCCTAAAGGGATATTTCAGGCAGCACAGTGGCGCAGTGAGTAGCGCTGTTGCCTCACAGCTAGAAGATCGCTGGTTCGAGCAATTAATTGAGGAGTTTGCATGTTCTCCCGTGTTTGTGGGGGTTTCCTCCAGGTACTCTGGTTTCCCCCATAGTCCAAAGACTTGAGCTATTGAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa37316

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000016219	Essential Splice Site	355	377	12	14
ENSDART00000016219	Essential Splice Site	355	377	12	14

Genomic Location (Zv9):

Chromosome 21 (position 24661113)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	25346787
GRCz11	21	25383392

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GGTTCTGCCACAATGTGGCCATGCCGTTCATGAAGATGCCCCAGAAAAAG[T/A]GTGTTTATTATCTATGACACTTTCAATAAAGCTTGTACATTATCCAGTAT

Long Flanking Sequence:

TTTTAATACAAAATTCCTTACATTTTCACACACATTTTAAGGAGAACAACTTTTTTATGTACAGATGTTTGTTGATTTTGTTTCATGTGGCAGATAAAGAAGGAATCTCTGTACACCTGGCGTATTGAACTCTCAAAGACAGAGAAATACTGGGAGGGCTGGTTTAAAGGACTGTCTTCCCTCTTTCTCAGCTGTTCTGTGCCAAAACTTCTTCTGCTGGCTGGTATGAATGTTTAGACATTTTGTTTAAAGTCTTATTGTGAAAAACAGCTACTTATATTTAATATATCACCCCATAGGTATTGACAGGCTTGACAAAGATCTTACCATTGGGCAAATGCAAGGTTAGGTGTTGATATTCCTGCTATTCAACGCAGACTTTATAGAGGGTACATCATACATTTATTCATTTATCTCCTTTTATTTCTGTACAGGGAAGTTCCAGATGCAGGTTCTGCCACAATGTGGCCATGCCGTTCATGAAGATGCCCCAGAAAAAG[T/C]GTGTTTATTATCTATGACACTTTCAATAAAGCTTGTACATTATCCAGTATGATGTATTTGTTTCTGATCACCTATATTTACATTTTTTTTCAGGTAGCTGATGCTTTAGCCACTTTCATGGTTCGTCACAGGTTCACTGAATTAAAGGAAGGGTTCCCCTGGTGAGAAATGGACATTTTGGCACATTCAAATAACTTTTAATATTTGGAAACTATTATAACTGATATAGAGGCTGATAAATGCACATTTTGATATGAAATTATCTGAGCCTGATTACAAAAAAAGACAAAAAATATTCCAGTGGAGATCAATTTAATTTAAAAACCCTAAAGGGATATTTCAGGCAGCACAGTGGCGCAGTGAGTAGCGCTGTTGCCTCACAGCTAGAAGATCGCTGGTTCGAGCAATTAATTGAGGAGTTTGCATGTTCTCCCGTGTTTGTGGGGGTTTCCTCCAGGTACTCTGGTTTCCCCCATAGTCCAAAGACTTGAGCTATTGAC

Associated Phenotype:

Not determined