Busch Lab

ZMP

arhgap4b

Ensembl ID:
ENSDARG00000015003
ZFIN ID:
ZDB-GENE-090311-38
Human Orthologue:
ARHGAP4
Human Description:
Rho GTPase activating protein 4 [Source:HGNC Symbol;Acc:674]
Mouse Orthologue:
Arhgap4
Mouse Description:
Rho GTPase activating protein 4 Gene [Source:MGI Symbol;Acc:MGI:2159577]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa15978 Nonsense Available for shipment Available now
sa37665 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa3230 Essential Splice Site F2 line generated Not yet available
sa43944 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa15978
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051182 Nonsense 65 943 2 23
ENSDART00000138792 Nonsense 65 957 2 24
Genomic Location (Zv9):
Chromosome 23 (position 18839097)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 18742036
GRCz11 23 18668379
KASP Assay ID:
2261-7537.1 (used for ordering genotyping assays)
KASP Sequence:
ATMTGAGCGARTACCTGCGCAGACGAGGAGAGATTGAGGCTGAATATGCC[C/T]GATCTCTGGAGAAACTSAGTGAGAAGTTCACAGTGAAGACCAAGAGGTAC
Long Flanking Sequence:
GACTGAACAAGTCAACAGGAGCTCTACACCAGCGGAGGAGACCATGACTTCACATGGAAAACTGAGAAAGGAAAAGGGGAGTCTGGCGGAGTATGAGACTCAAATCAAAGGTAAATACTTGATCCCTTGTTCTCATGTTCACTTCATGAGGTAGTGGTAGCAGAATGTGCATTTCTGGATGGAATGTGTGAGATGTGGGCCTGCTCTGTGATGTATTTATAGGCAGGATTAGGGATGCTGTCTTCCCTCATCCAATCAGCTCTCAGCCTCAGGCCAGGGACACTAGTGCGGGGGGATACAAAGTCTTCAGTTTATGCCACTTTTGTGCTAAAAACCACCTAGACATGATCTCTTTGCTTCTGTTTCTTTGCCTAGAGGTGCGTGGTCAGCTCTCAGAGCAGCTTAAGATCCTAGACGCGCAGCTGGAGGTCAAGACACAACAGCTGCAGGATATGAGCGAGTACCTGCGCAGACGAGGAGAGATTGAGGCTGAATATGCC[C/T]GATCTCTGGAGAAACTGAGTGAGAAGTTCACAGTGAAGACCAAGAGGTACCTCTTTTTAGCATTCATGAAGATAAACTGAGATGTGACCTGTTAATGGACTTTGTTGTAAGAATGAATCGGTGAATCGTTCATGCAGCAGAATAGTTCAGTTTAGTAACCAAAAAAGTGACTTTCTCTGTGAGTGAGATATTGAATCATACACTCAATCGATATGTTCAAACACACTGCTTCATTTAGTAAACAAAAAGGTGATTGAGTGAAACAGGTTGTCATTTGACTCCTTTAGACTTAATTTGCCTCAATGAATCATTTAGGCCTCTCTGGTAATCTCCACAACACAGGTAATGTGTTACAATCATACTGTACACATTCATACCATGCAGAAGATATCTTTAGCAGTCACAAAGAAATTTCTTAAAAAGAGTATTTACAATGCAGCTTTTCTCTGTGACCAAATCATTGAATCATTTACTCAACTGATTTGTTTAAACACTCTGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37665
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051182 Essential Splice Site 134 943 3 23
ENSDART00000138792 Essential Splice Site 134 957 3 24
Genomic Location (Zv9):
Chromosome 23 (position 18832942)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 18735881
GRCz11 23 18662224
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGCGCCTCTCACACTGCATAGAGGACACACACCGCCTGGCAAAGCGGG[T/G]ATACAAATCTCTCCCACTCTATTACCAGCTCCGACAGTTAATTCTCCCCC
Long Flanking Sequence:
GGCAAAGGCTGTCAATACTGATGTAAATGTGATTTTTCAGCTTTAATTTTTAATAAATTCGCAACAATTAAAAAAAAAATCTTTTTTCACATTGTCATTAGGGGGTATTGTGAGTAGAATTTTGAAGAAATAAATGAATTTAATAAGGCTGTAACAAAAAAAAAAATGCAGAAAAAAGTCAAGCGCTATGAATACTTTCCGGATGCACTGCAAGTGAGAAAGATTAGATAATCTCTTTAACTTGAATGTACATCACAATACAGTAAAGATCTGTCTGTACTTCCTTTTACTTCACATCTTTAACCCAGTTTCTCCTTTACTCTGCTCTATCTTTAGAAAGGAGCAGTTGGACCTGTCGGTGGCTCAGTGCTGGTCTGTTCTTCTGACCCAAACCAGGCAGGAGAGCCGAGATCACAGTTCACTCAGTGAGCTCTGTGGCAACACACTCACGCAGCGCCTCTCACACTGCATAGAGGACACACACCGCCTGGCAAAGCGGG[T/G]ATACAAATCTCTCCCACTCTATTACCAGCTCCGACAGTTAATTCTCCCCCTCCTCCTTCTCTTCCTCTCTTATTTACCGACATAACACACTCCCACACAAAACACAGCCAAACCATCTTCCTCCTTTCAAACTGACTCGTATTCTCTGTTTCAGAGCAAGGAGGTTGGACTCCAGATGCAGGATGAGCTTTTGAAAATCACCACAGAGCTGCAGACGGTAAGTGGAAAGGCTGTCTTGCTGCGAACGTGCTAAATTTACACAGAAGAACACGCTCTAGTGAACTGAAATAGTCCAAATGGCATCAGCTTCGAGTTGCATCATCTCACTGCGGTCAGAGAAAGCATGATTAAACTTGACTAAATACCTCACCATGCACGTATTTGCTCATGCATCCACAGCTGATTGTGTTTGCGTGGCCTTCTATAGAGTCTTAGGTTTCAGAACGTTTTTTGGTCCATCATCTAGCACACAAAATAAGCCTACACGACGCTCCAGCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa3230
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051182 Essential Splice Site 135 943 4 23
ENSDART00000138792 Essential Splice Site 135 957 4 24
Genomic Location (Zv9):
Chromosome 23 (position 18832789)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 18735728
GRCz11 23 18662071
KASP Assay ID:
554-3176.1 (used for ordering genotyping assays)
KASP Sequence:
CACAGCCAAACCATCTTCCTCCTTTCAAACTGACTCGTATTCTCTGTTTC[A/T]GAGCAAGGAGGTTGGACTCCAGATGCAGGATGAGCTTTTGAAAATCACCA
Long Flanking Sequence:
ACAAAAAAAAAAATGCAGAAAAAAGTCAAGCGCTATGAATACTTTCCGGATGCACTGCAAGTGAGAAAGATTAGATAATCTCTTTAACTTGAATGTACATCACAATACAGTAAAGATCTGTCTGTACTTCCTTTTACTTCACATCTTTAACCCAGTTTCTCCTTTACTCTGCTCTATCTTTAGAAAGGAGCAGTTGGACCTGTCGGTGGCTCAGTGCTGGTCTGTTCTTCTGACCCAAACCAGGCAGGAGAGCCGAGATCACAGTTCACTCAGTGAGCTCTGTGGCAACACACTCACGCAGCGCCTCTCACACTGCATAGAGGACACACACCGCCTGGCAAAGCGGGTATACAAATCTCTCCCACTCTATTACCAGCTCCGACAGTTAATTCTCCCCCTCCTCCTTCTCTTCCTCTCTTATTTACCGACATAACACACTCCCACACAAAACACAGCCAAACCATCTTCCTCCTTTCAAACTGACTCGTATTCTCTGTTTC[A/T]GAGCAAGGAGGTTGGACTCCAGATGCAGGATGAGCTTTTGAAAATCACCACAGAGCTGCAGACGGTAAGTGGAAAGGCTGTCTTGCTGCGAACGTGCTAAATTTACACAGAAGAACACGCTCTAGTGAACTGAAATAGTCCAAATGGCATCAGCTTCGAGTTGCATCATCTCACTGCGGTCAGAGAAAGCATGATTAAACTTGACTAAATACCTCACCATGCACGTATTTGCTCATGCATCCACAGCTGATTGTGTTTGCGTGGCCTTCTATAGAGTCTTAGGTTTCAGAACGTTTTTTGGTCCATCATCTAGCACACAAAATAAGCCTACACGACGCTCCAGCTTTGCAGAGCTGTGAGATCAAGCCCACTGACCCTGGCCCACAGCAGCTGCGTGCTCTCTACCCTCCAGTAAACAAACAGCTTGCCTACCGTCTAAGTGTCTTGGCTCAAGCATTTGTGTGTGCGCGTGGGAGTGTGTGGGTGTGTTCTTTAAATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43944
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051182 Nonsense 162 943 5 23
ENSDART00000138792 Nonsense 162 957 5 24
Genomic Location (Zv9):
Chromosome 23 (position 18830005)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 18732944
GRCz11 23 18659287
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCATGTTGTAAAAGTGTTGAATGTTTTGCAGGCTTTGAAAACTTATCAT[C/T]AATACCACATCGACTGTCTGGCTGCAGAAGGCAAGCTCAAAGAAGCCACG
Long Flanking Sequence:
TTTTTTTCTGGAAAAAGTCTTATTTGTTTTATTTCGGCTTGAATAAAAGCAGTTTTTAATTTTTAAAACACCATTTTAGGGACAAAATTATTAGCCCCTTTAAGCTATATTTTTTTCTTGATAACCTACAGAACAAACCATCACTATACAATAACTAATGTTAACTAGTATAACAATCATAATGATGATGATGATGATGTTAATAATAATGACAATAATAAAAGTATTATTGTTATTTTTATCTAATAAGTCATTTTTAATCTAGCAAAATAAGCTATTACATTAAACTACAATGAAATTATTTTACCACAAATCTGTTATATAATGACTAGTATAATAATAATCATAATAATCATTTATATAATCATTTATCTGTTTTTTCTCCCTAGCCAGATAGTTCTGTTGTTTTATAAAAAAGCTTATTTTTAGCATCAAAAAGAATTTTTGCCTTGCATGTTGTAAAAGTGTTGAATGTTTTGCAGGCTTTGAAAACTTATCAT[C/T]AATACCACATCGACTGTCTGGCTGCAGAAGGCAAGCTCAAAGAAGCCACGCGACTAGAAGAGAAGCAGACGGGCAAGTCAGCTGATCTCGGCCTCAGCCAATCAGGAGGGCAAAGACGCAGTTCTGTCAAAAAAATGGAGAGACTGATGGAGAAGGTAAACGCATCAGTTTGCGAGAATGAAAGCTGGTAACATCCGGAGCTCTGCTCTGTGAAGATGGCACAGGAAGAGCAACATCTCACTTTATCTCTGTACGTGTGCTTGCTTCACAGAGACAAGGCAAAGTACAGGAAACCCAGCTGAAGTGCACTAAAGCTCGCAACGACTACTTGCTCAACTTGGCAGCAGCTAATGCCTCCATGAATAAATACTATCTGCAGGACATTTGCACGCTGATTGATGTGAGTCTAAAACAGCACTGTCCCATTAGCATCTGTCTAGACGCTCTCTAGGATGTGCTTATGCTTTAGTTCCCTTTTCATTTTGAATTGACCTCTGACC
Associated Phenotype:
Not determined