Busch Lab

ZMP

cdh2

Ensembl ID:
ENSDARG00000018693
ZFIN ID:
ZDB-GENE-990415-171
Description:
Cadherin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q90275]
Human Orthologue:
CDH2
Human Description:
cadherin 2, type 1, N-cadherin (neuronal) [Source:HGNC Symbol;Acc:1759]
Mouse Orthologue:
Cdh2
Mouse Description:
cadherin 2 Gene [Source:MGI Symbol;Acc:MGI:88355]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa206 Nonsense F2 line generated Not yet available
sa16882 Essential Splice Site Available for shipment Available now
sa15918 Nonsense Available for shipment Available now
sa32283 Nonsense Available for shipment Available now
sa11989 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa206
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024627 Nonsense 28 893 2 16

The following transcripts of ENSDARG00000018693 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 17789419)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 17843919
GRCz11 20 17743502
KASP Assay ID:
554-0152.1 (used for ordering genotyping assays)
KASP Sequence:
TTTTGTGTTTTTGGCAGGTGGCGGTCCAGGGCACAGGGGCGATGCCATGT[C/T]AGCCTGGTTTCACCGAGAACGAGTACAACGTCATGACAGCCGACGTCATC
Long Flanking Sequence:
CCTGACCTCATCAGTCTAATTACACCCACCTCAAAATAACAGATGCCCCAGTGCCGGAGGGGGGAGGGGGGCAAACCCTCACCATCCTTGAAGGAAGAATAATTCAAAGCCAAGCCAGCAAATCGTCATGCAATGAACCTTATTTAATTTCGCCGATCTGCTGCAAATTAGCGAGTAATCGTTGAAAAATACAATAGCATAGCTAATTCAAAGAGTTCATTTCGAGCGTGATCAATGGACTTGGCGGCTCTGGAAAGGCTCATCACGGTGCTTTTCTTGAGCGGAGTTCTGCCTCATTTCCTCTGTTTATGGTGAAAGAGCGTGATCGTTATGTCCATCGATTCCTCTTGGGATTCGGGATATTTGGCTCTCGCTGTGGTGTAGGTTGGCCCGCGCTGAGGGGCGATGTGTATTAATCACCATTAATCGGGGGATTAATTTGTCTGGTGCTTTTGTGTTTTTGGCAGGTGGCGGTCCAGGGCACAGGGGCGATGCCATGT[C/T]AGCCTGGTTTCACCGAGAACGAGTACAACGTCATGACAGCCGACGTCATCACCGAGGGACAAGTTCTGCTCAAAGGTAAACAAAGACGTTTTCTTTACATGCATACTTAGAATAAACGGACCAATCCAAGCGGTGAGGCAGAGCGCTCCCTTACCAGGCTTGGGTTTCCAGTGTGAAGAGAAAAAGAGTTGGGGGAAGGGTGGGCTTTATGCTTGTATGTGAAAGAACGAGAGGGGGAGGAGGGTTAAGTGTTAGGGTTGCTTTAGTAGGGGGTGTTTATAGAGGGTGATATGTGTGCGAGAGAAAGAAAGGAGCAGGAGGAGGAGAACAGCTCTGTGTTTTGGTGGAATGTGTTTTGAAGCTTCACAGTGTGAAGTATCTGGGTGCTTGAATCACCCTCCCCCACTGTGGATGAATCCCTGTTGTGATCGATAGCATTGATTAGACCAGCCCATATCCATACAATTAGTCGATGGCACACATCCCAGTCAGCCATCTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16882
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024627 Essential Splice Site 52 893 2 16

The following transcripts of ENSDARG00000018693 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 17789495)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 17843995
GRCz11 20 17743578
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAACGTCATGACAGCCGAMGTCATCACCGAGGGACAAGTTCTGCTCAAAG[G/A]TAAACAAAGACGTTTTCTTTACATGCATACTTAGAATAAACGGACCAATC
Long Flanking Sequence:
CCTCACCATCCTTGAAGGAAGAATAATTCAAAGCCAAGCCAGCAAATCGTCATGCAATGAACCTTATTTAATTTCGCCGATCTGCTGCAAATTAGCGAGTAATCGTTGAAAAATACAATAGCATAGCTAATTCAAAGAGTTCATTTCGAGCGTGATCAATGGACTTGGCGGCTCTGGAAAGGCTCATCACGGTGCTTTTCTTGAGCGGAGTTCTGCCTCATTTCCTCTGTTTATGGTGAAAGAGCGTGATCGTTATGTCCATCGATTCCTCTTGGGATTCGGGATATTTGGCTCTCGCTGTGGTGTAGGTTGGCCCGCGCTGAGGGGCGATGTGTATTAATCACCATTAATCGGGGGATTAATTTGTCTGGTGCTTTTGTGTTTTTGGCAGGTGGCGGTCCAGGGCACAGGGGCGATGCCATGTCAGCCTGGTTTCACCGAGAACGAGTACAACGTCATGACAGCCGACGTCATCACCGAGGGACAAGTTCTGCTCAAAG[G/A]TAAACAAAGACGTTTTCTTTACATGCATACTTAGAATAAACGGACCAATCCAAGCGGTGAGGCAGAGCGCTCCCTTACCAGGCTTGGGTTTCCAGTGTGAAGAGAAAAAGAGTTGGGGGAAGGGTGGGCTTTATGCTTGTATGTGAAAGAACGAGAGGGGGAGGAGGGTTAAGTGTTAGGGTTGCTTTAGTAGGGGGTGTTTATAGAGGGTGATATGTGTGCGAGAGAAAGAAAGGAGCAGGAGGAGGAGAACAGCTCTGTGTTTTGGTGGAATGTGTTTTGAAGCTTCACAGTGTGAAGTATCTGGGTGCTTGAATCACCCTCCCCCACTGTGGATGAATCCCTGTTGTGATCGATAGCATTGATTAGACCAGCCCATATCCATACAATTAGTCGATGGCACACATCCCAGTCAGCCATCTCAATACGCTCAGTCAATCCGGCAGGGGCCACATTTGTGCTGCGGTTGTAAACTTGGGAGGCCTTATAACATCCCAGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15918
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024627 Nonsense 517 893 10 16

The following transcripts of ENSDARG00000018693 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 17848927)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 17903427
GRCz11 20 17803010
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGTCRATGCTAACGACTTTYACAGCTCATGATCCAGACAGATATATGCAG[C/T]AGACTATTAGGTATTAAAGMAMACACATCTRCATATATACAYATGGTTTC
Long Flanking Sequence:
CCATAGACATGGGTTCAAATGCAGAGCAAAAGACGGTCTCCATGGAAACAGCTTCCACCTGCTGTTCAGCCGAGTTAATGGTTTATATGTCTCTTAATTGAGAATGAGTTATTCATTAATTATTATTCAAACATTTCTCTCCTGTGTATTTAATTGCAACACAATTCATTTATTGTATCGTTTCGATTCTTTCCCCTAACAGATTGTGAAGCGGAGTTAACTTGATTGTGTGTCTGCTTGTGTGTTCTTGTGTACAGCCAGTTGATTTCGAGATGAATCGATCATTCATGCTGACTGTTGTCGCTGACAATGAAGTGCCACTAGCGAGTGGAATCCATCGCACACGCCAGTCTACAGCCACCGTATCCATCCGCGTCATCGATGTGAACGAAAGCCCCAACTTTGACCCCAACCCCAAACAGATCAAACTGGAGGAGGGTCTTCCGCAGTGGTCAATGCTAACGACTTTCACAGCTCATGATCCAGACAGATATATGCAG[C/T]AGACTATTAGGTATTAAAGAAAACACATCTGCATATATACATATGGTTTCTAGCAATGGAAAGCATTTTTGGAAGTGTAATGCATTTTTATAAACTATTTACAGTTTACAAAAATAAAACTAATATGAAATAGTGTTGTCAGGCGATCAAATTATTTTAAAGGTTTTATTTAACAAAGGATTTCCTGTTATAATTATAGACAGATTATTATTGATAAAGTGCATTTTTATAGCACTTAATAATGTTTTTTTTTTTTATTTGTTTGCACCTTTATATTTATATAATATATGTTAAATATAAATGTTAAATGTAAATTCTTAACGCACTGTTCGTTTCATTTTGACAAATATTCTATACAGTCTAAACACAACAGAAGTAGTAGACTAATTTAAAAATTGGCTACTCCACATATAACCATTGTGAAAATGTAAACGAAATGAAAACGTTAACCACATCTTCTTGTGTGTTTGTGTTTTAAAGTTACTCTAAATTATACGACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32283
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024627 Nonsense 558 893 11 16

The following transcripts of ENSDARG00000018693 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 17849522)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 17904022
GRCz11 20 17803605
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCATTGCTGTTTTGGATCGAGAATCTCCTTACGTGAAAAATAACCTTTA[C/A]AACGCCACATTCATGGCTTCAGACAATGGTAAGAGCAATGTTGTGTGTGT
Long Flanking Sequence:
CTATTTACAGTTTACAAAAATAAAACTAATATGAAATAGTGTTGTCAGGCGATCAAATTATTTTAAAGGTTTTATTTAACAAAGGATTTCCTGTTATAATTATAGACAGATTATTATTGATAAAGTGCATTTTTATAGCACTTAATAATGTTTTTTTTTTTTATTTGTTTGCACCTTTATATTTATATAATATATGTTAAATATAAATGTTAAATGTAAATTCTTAACGCACTGTTCGTTTCATTTTGACAAATATTCTATACAGTCTAAACACAACAGAAGTAGTAGACTAATTTAAAAATTGGCTACTCCACATATAACCATTGTGAAAATGTAAACGAAATGAAAACGTTAACCACATCTTCTTGTGTGTTTGTGTTTTAAAGTTACTCTAAATTATACGACCCCGCCAACTGGTTGGAGATCGACCCAAACAACGGACGAATTTCCACCATTGCTGTTTTGGATCGAGAATCTCCTTACGTGAAAAATAACCTTTA[C/A]AACGCCACATTCATGGCTTCAGACAATGGTAAGAGCAATGTTGTGTGTGTCTGTGTGTGTGTGTGTGTGTATGCATAAGCAGTTAAGATTGAGTGATTGAGTGATTCCATTGATTTTAGCTCTAGGGTGGAACTGCAACCGAACAGACTCAGAAATATACCCATGCCCACACATCCATGCTTAATGATCACACCAATGACAAATGCAAACTCATTCCCAACGTCTGCGTGTTCACTTTCCCTGGGTGGCTCTTTGAAGCAGCTCTTCTTTCTAACACACACATATGCACATACACTACCCGCTGTGTGAAAGAGTCTACAGAAGTCTGCTAGGCCGCTATTCTGCTGCCGTGTTTAACATTCTTGCTGCATCAGAGCTGTGAAACAACCCCCCTCTCTCACACACACACACACACACGCTGTAAATTTGAAAGCTTGTCTCCAGAAACACTCACAAAGCAGTTGTGCCGTTTTCGTATACGGTATTCCAGCACAAAACCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11989
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000024627 Essential Splice Site 568 893 11 16

The following transcripts of ENSDARG00000018693 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 20 (position 17849552)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 17904052
GRCz11 20 17803635
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACGTGAAAAATAACCTTTACAACGCCAYATTCATGGCTTCAGACAATGG[T/A]AAGAGCAATGTTGTGTGTGTCNNNNTGTGTGTGTGTGTGTATGCATAAGC
Long Flanking Sequence:
ATGAAATAGTGTTGTCAGGCGATCAAATTATTTTAAAGGTTTTATTTAACAAAGGATTTCCTGTTATAATTATAGACAGATTATTATTGATAAAGTGCATTTTTATAGCACTTAATAATGTTTTTTTTTTTTATTTGTTTGCACCTTTATATTTATATAATATATGTTAAATATAAATGTTAAATGTAAATTCTTAACGCACTGTTCGTTTCATTTTGACAAATATTCTATACAGTCTAAACACAACAGAAGTAGTAGACTAATTTAAAAATTGGCTACTCCACATATAACCATTGTGAAAATGTAAACGAAATGAAAACGTTAACCACATCTTCTTGTGTGTTTGTGTTTTAAAGTTACTCTAAATTATACGACCCCGCCAACTGGTTGGAGATCGACCCAAACAACGGACGAATTTCCACCATTGCTGTTTTGGATCGAGAATCTCCTTACGTGAAAAATAACCTTTACAACGCCACATTCATGGCTTCAGACAATGG[T/A]AAGAGCAATGTTGTGTGTGTCTGTGTGTGTGTGTGTGTGTATGCATAAGCAGTTAAGATTGAGTGATTGAGTGATTCCATTGATTTTAGCTCTAGGGTGGAACTGCAACCGAACAGACTCAGAAATATACCCATGCCCACACATCCATGCTTAATGATCACACCAATGACAAATGCAAACTCATTCCCAACGTCTGCGTGTTCACTTTCCCTGGGTGGCTCTTTGAAGCAGCTCTTCTTTCTAACACACACATATGCACATACACTACCCGCTGTGTGAAAGAGTCTACAGAAGTCTGCTAGGCCGCTATTCTGCTGCCGTGTTTAACATTCTTGCTGCATCAGAGCTGTGAAACAACCCCCCTCTCTCACACACACACACACACACGCTGTAAATTTGAAAGCTTGTCTCCAGAAACACTCACAAAGCAGTTGTGCCGTTTTCGTATACGGTATTCCAGCACAAAACCCACCTGTAATCCAGTTTCAGCACACACTAAA
Associated Phenotype:
Not determined