Busch Lab

ZMP

ENSDARG00000088310

Ensembl ID:
ENSDARG00000088310
Human Orthologue:
MLLT4
Human Description:
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 [Sour
Mouse Orthologue:
Mllt4
Mouse Description:
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 Gene

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa10884 Essential Splice Site Available for shipment Available now
sa28787 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13762 Nonsense Available for shipment Available now
sa15870 Nonsense Available for shipment Available now
sa16881 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa10884
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000124888 Essential Splice Site 89 962 4 20
Genomic Location (Zv9):
Chromosome 17 (position 6082065)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 6161001
GRCz11 17 6318231
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TATGCACWTCTCAAGTTCTTAWCATGTGTATGYCATTCATTTCWGTTTTC[A/G]GATGAGGACTCTTTCTTGCTTTCTGTSATAAACGATATTAAMAGCTCCRC
Long Flanking Sequence:
AATATTATAGAGGCTGTATGAGATCACCTGGACAGAAAAAAAATGATGAGACACTCTAAACCTAAAAGAGCTCTGGAAAGTGCTAAAATAGGCGTGATATAACACAGCACATTATTTCTTATATTTTCTGTTTGTTTTTAATGAAGGGACTGATTGATTAGATATTGTGCAAAAGTCCTAAGGCAACAAAGCTGGTCTGGTGCTTAGGACTTTTGCACAGTACTGTATAATTCTAGCTTTTTGCAAGTTTGCTATTTGCTGTACTGTATTTTGATCATTATATGCCTGTTATACTTAACCACAAGTCAACATCCCCCTTAAAATGAACATTTCTTTTTTTTTTTTTTATTGAAGCACTAAACAAGACGACTTAGAAATGAAGTGGACTCTCCCGCTCAGCATTTCTTTAAAGGAAAAAGGTACAATAAAACCACTCAGTTTGCAGGAATATATGCACTTCTCAAGTTCTTAACATGTGTATGTCATTCATTTCTGTTTTC[A/G]GATGAGGACTCTTTCTTGCTTTCTGTGATAAACGATATTAACAGCTCCACCATTCACTTCAAGCTCTCGCCGGCGTACGTGTTTTATCTGGTCGGACGATTCTTAACCAGCAAAACCAGCCAGAGAAATAAATCCCACAAGCAGACTGAGCAGAAAATCTGCCTGGTGTTTGAAAAGATTGTGCGGATGATTCAGGATGTCATTCAGGTAAATAAAAGCCTGTAAGTGTATTGATCACAATTAAATTCCTTAATCTACACTTGAAGTATTATATAGTAAATTATAAACCCCCTGTGATTTTTTTATTTTTATTTTAATTTTTTATGTTTGATGTTGAACAGATCAAGGAGTTATATTCCAAGGATATTATATTTGTCATGATTATATATCATTAATATCAGTGGAACAAACTGTATTTATCTTTTTATTTTATTTTTTACTTTTTATTTAAGATTTTTTCAATATATTGTTTTACAGAACAACCCCTTCCCCAACCATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa28787
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000124888 Essential Splice Site 490 962 11 20
Genomic Location (Zv9):
Chromosome 17 (position 6064639)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 6143575
GRCz11 17 6300805
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TAAAGAAACCTTTGCACAGCGGAATGGGAATAAGCATCGTAGCTGCCAAG[G/A]TAAAATAGAAAAAACTAAACTGTTATTGTCACTGGGAAAATATGCGATAC
Long Flanking Sequence:
ATTCAAAACCAGTTATAATAATTATTTTTATTATTAAAACCAAAAGTTGCATCTGTTAACATTAGTTTGTTCACTACTAGGAACAAGTATCAAAAGTAAACACTGTAAAATATACTGCACATTCTTAGTCTGTTAATAATTATAGAATAATAATAATAATTATACGCCATTAAGAAAGCAGACAGACTTTTACATTTTTTTTGCAAAGATATGATAGTTGTACTAATAGTGTACGTTTTATTTGCAAAGGCAGAACAACAGTAACATGCTAGTTGAATCTTCTATTTTTCCACTAACTATCGGAAATGTCTTAATCTCAATGTTGTAACTTCTTCTCCATCACTGTCTGACTCTGATCATTTTTTTATTAACTAAAAACTGAAACTGTTAATCAACTAAAGTAATGTTTTTATTTTCATTGTTAGAAATCTGAACCAGTGAAGATAACTCTAAAGAAACCTTTGCACAGCGGAATGGGAATAAGCATCGTAGCTGCCAAG[G/A]TAAAATAGAAAAAACTAAACTGTTATTGTCACTGGGAAAATATGCGATACTGTCATTGAGTGTTGAAATTAACGATATTTTAACAATATAACTAACTTGCAAAATGCTGTTTCATTAGCAATTAAAAAAACTTTTATTTATGTAACAATCATACTATTAAAGAGGTAATACAGTATATACTATTCTGAGCTAATTGAATCAAAAAAATGTCAAGGTGCAAATATTTAAACATGATGGGGTCTATTTTGGCGTTCCATGCGCAAATTGCAAAACGCACGGCGCAAACGCATTAGGGGTTATTTTCTTAATGAGTTATGGGTGTGTTTTGAGAATAAACCAATCAGAGTCTCACCTCCCATTCCCTTTAAGAGTCAGTTGCATCGTACCATGGTGCATTAGCTATTTACATGACGACTTTGTAAGTGGAAAAACTAAACACTTCATTAGCGAGAAAACAGTTAAACAGAGGATCTGCAGCGCTGTTGTAGATAGGGAAACCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13762
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000124888 Nonsense 629 962 15 20
Genomic Location (Zv9):
Chromosome 17 (position 6057674)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 6136610
GRCz11 17 6293840
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAAGCAAACCCCAAACAAAACCAGGAGCTGCTCAAGAAGACGCTGGAGTA[T/G]CGCTCAAAYCCYAACCTGACATGTGAGTGWTTGGATTMTTTTGTGTGTGT
Long Flanking Sequence:
TTCGGTTTCCCCTATAGTCCAAATACATGCGATACAGGTGAATTACTTCGGCTAAATTGTCCGTAGTGTGTGAATGTGTGTTTGGATGTTTCCCAGAGATGGGTTGCGGCTGGAAGGGCATCCGCTGCGTAAAAACTTGCTGGATAAGTTGGCGGTTCATTCCGCTGTGGCGACCCCAGATTAATAAAAGGACTAAGCCGACAAGAAAATGAATGAATGAATGTTGTTGTTTTTTTGGGCGAACTATTCCCTTAATACATTAACTGAACCAACAATATTTGTTCTGTTGCAATATTAGTCAAGACATCAGATTATCCATGCATGCTTGTGTCACATTTGTTAGATCCTGATAGCAGTGGAGCATCCAAAGAGAAGATCGGCGCCTTTGATGTCCATGACCGAACTGAAGCATGTGTTTCAGAAACCACCAGAATCCAGAACAGCATCAGCAAAGCAAACCCCAAACAAAACCAGGAGCTGCTCAAGAAGACGCTGGAGTA[T/G]CGCTCAAACCCCAACCTGACATGTGAGTGTTTGGATTCTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTTTGTGTTTGTGTGTGTGTGTGTGTGTGTTTCTTTTTGTTTTGCGGATGTTAACAAGAGCTTAGTGTTGTCGCCTCACAGCTGGTCGCTGGTTCAAGTCCCAGCTGGTCAAGTTGGTATTTCTATCTGGAGTTTACATGTTCTCCTCAGAGGAAACTCACGCCAACACAGGGAGAACATGCAAACTCCCCACAGAATAGCCAACTGACCCAGCCAAGGCTCACACCAGCAACCTTCTTGCTCTGAGGTGGCAGCGCTACCCACTGCGTTACCGCATCGCCCCTGTTCTCTTTAAACCCTATTTAAATTTCCATTAGATAACCAGGAAATGCCTGTGGATTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15870
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000124888 Nonsense 711 962 17 20
Genomic Location (Zv9):
Chromosome 17 (position 6056085)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 6135021
GRCz11 17 6292251
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCAGAACCACTGAACAGCCTCTGCATATTGCTGCATTCTCCAGGGATCAG[C/T]AGAAGATCAACTTCATGGTATTTTGTGTGTCTGTTTTATTGCCCTGTTTG
Long Flanking Sequence:
CAAGTAAGACTTTCTCCAGAAGAAAAAAATACTAGCAGACATACTGTGAAAATTCTCTGCTCTGTTAAACATCATTTGGGAAATATTTAAAACAGATTTTTTTTTACTAATTCTGAATTAAACTGTATATTAGCATTTTTCATATTGATTTTAAAAATATATTTTATTTAATTTTTTTATTAATTGTTTTTAATTTAAATTTTATTTGTTGCTTAATTTTTTTTGTTATGATTTTGGTGTTTGTTTTAGTTCATAATCATAACCCTGGTATACAGATCTTTTTAAGGCATTCATAAACAGTCCCGTTCTTATTCTTTTTATGTTGATATCGTTTGATATATTTCTACATCTCACCCCAGGGGAAACCTTCAAACGCTTCTTTAAACACAGATATTTATCAGAGAGAATATCTGACCCTGCCGTCCTCCAAACTGCACAGCAATAAAGCACCCAGAACCACTGAACAGCCTCTGCATATTGCTGCATTCTCCAGGGATCAG[C/T]AGAAGATCAACTTCATGGTATTTTGTGTGTCTGTTTTATTGCCCTGTTTGATATTTGTGCTTCCAAAAGTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCATCCGTCGATCTGTCTGTTTGTGTCATCCATCCATCTATTATCCATCCATCTATCATTCTTTTTATCTATTGTCCGTCCATTAATCTATCATTCTTTCTATTATTCTATCTATATCCATCCATTCCTCCATCTGTCTCTATTTATTTACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16881
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000124888 Nonsense 819 962 18 20
Genomic Location (Zv9):
Chromosome 17 (position 6054768)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 6133704
GRCz11 17 6290934
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATTCAGCACCTTCCGCCRGCCTGCAGAYAGCAGAAYTACWTCCCAAACR[C/T]AGCATCTGKATCAATGCTTCGGTGCTTCAGCGTCTCAGAGCAAGGTATTW
Long Flanking Sequence:
TAACTTTTGGACTAAACCAACAGCTGGGTTATTTTTTTAAGCCGAATGTTTGGGTTTTTCATATTTTATCCAATTTGGGTCGAACTAACAATACCTTTACTTGTTCCAACACTTTAGTGTTGAGTAAATGATGACAGAATAGTCTTTTTTAATTGAACTATCCTTTTACAGTAATAATGGTTGTATCCACACAGAAACAGGCGCATTCTCATGATGACCTGTGGAGTGCAGAGAAAGGGCACTCTCTAGTGGACAAACAGAAGTACTTGAAGAAACAGCCTGAAGTGAGCAAATGGATCAGTCTTGCAACTATCAGTCCAATAAACTCCAGTTTCTCCAGCATGGGACACAGAAATGAGCTGTGGAAAATCCCGACAGCTGCCCAGTCTGTGCCTCTGTCACAGCCGAAGCGTCTGGACGTCCCGTATTCACCACAAACCAACAAACCTTCATTCAGCACCTTCCGCCAGCCTGCAGACAGCAGAATTACATCCCAAACG[C/T]AGCATCTGTATCAATGCTTCGGTGCTTCAGCGTCTCAGAGCAAGGTATTTATATTAGTTTTGAAGATTTAATTTCAATATTATCTTTTTAAAGGTCCCATGAAATTAAAATAAAGTTTTTTAGATGTTAGTATTGTTTGTTTTTAGGATACCTACAAGCTAAAACAGTGGCAAAAAGCATGTTTGTCACTTCCGCATAAATGGATCAATGTAGGGCTGGGCGATATAGCGAAAAAAAATAAATAAATCACGATATCATGTTTCATATCATTCGATATCGATAATTATCGAATATTTATAGCAATACATTAAGAATATTAGTTTTTTTAACCACTTTATTTGTGTTTACCAACATCAATCAGGCCTTTATTTGTCACATACACTTTCATATAGTGAAATTTAACCCCCCGACCATACACAAACATCACAATTTTCAGGGGAAGACATTTAGAAAAAGGAAGTAAGATACATTTCAGGAGAGGGAGGCGAAGAAAAACTCCC
Associated Phenotype:
Not determined